Role of Polyphosphate as an Inorganic Chaperone to Prevent Protein Aggregation Under Copper Stress in <i>Saccharolobus solfataricus</i> by José Acevedo-López, Gabriela González-Madrid, Claudio A. Navarro, Carlos A. Jerez

“…In <i>Escherichia coli</i>, polyphosphates also function as inorganic molecular chaperones. The present study aims to investigate whether polyphosphate serves a similar chaperone function in archaea, using <i>Saccharolobus solfataricus</i> as a model organism. …”
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Feature selection using a multi-strategy improved parrot optimization algorithm in software defect prediction by Qi Fei, Guisheng Yin, Zhian Sun

“…Experiments conducted on eight benchmark test functions validate the superior performance of MEPO in terms of convergence speed and solution accuracy. …”
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A survey on the applications of transfer learning to enhance the performance of large language models in healthcare systems by Anmol Rahujo, Daniya Atif, Syed Azeem Inam, Abdullah Ayub Khan, Sajid Ullah

“…This research analyzes different transfer learning methods, including inductive, transductive, and unsupervised techniques, while demonstrating their effectiveness in detecting COVID-19 from chest X-rays and multi-source disease evaluation. …”
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Experimental study on solution possibilities of multiextremal optimization problems through heuristic methods by Rudolf A. Neydorf, Ivan V. Chernogorov, Orkhan Takhir Yarakhmedov, Victor V. Polyakh

“…Each method can provide any desired accuracy of the extremum problem solution, and it utilizes an acceptable time resource.…”
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Species-level enumeration of low-concentration lactic acid bacteria in breast milk by Yue Sun, Qiming Li, Mengling Hu, You Wu, Yunchao Wa, Hai Lu, Shilong Jiang, Hui Wang, Qiaosi Wei, Yujun Huang, Ruixia Gu, Chenchen Zhang

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IGFBP7 promotes the proliferation and differentiation of primary myoblasts and intramuscular preadipocytes in chicken by Wanzhuo Geng, Yulong Guo, Botong Chen, Xi Cheng, Shuohan Li, Mohammed Kamal Challioui, Weihua Tian, Hong Li, Yanhua Zhang, Zhuanjian Li, Ruirui Jiang, Yadong Tian, Xiangtao Kang, Xiaojun Liu

“…We then examined the expression patterns of IGFBP7 across different stages of proliferation and differentiation in CPMs and intramuscular preadipocytes via qPCR, and explored the biological functions of IGFBP7 through gain- and loss-of-function experiments and a range of techniques including qPCR, CCK-8, EdU, flow cytometry, Western blot, immunofluorescence, and Oil Red O staining to detect the proliferation, differentiation, and lipid deposition in CPMs and intramuscular preadipocytes. …”
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Study of the phytotoxicity of margines on Pistia stratiotes L. by Ajdi Mouhcine, Gaga Younes, Assouguem Amine, Kara Mohammed, Benmessaoud Safaa, Ullah Riaz, Ali Essam A., Skender Azra, Singh Jyoti, Bahhou Jamila

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Big data in visual field testing for glaucoma by Alex T. Pham, Annabelle A. Pan, Jithin Yohannan

“…In this study, we review the use of big data for evaluating the reliability of VF tests, gaining insights into real-world clinical practices and outcomes, understanding new disease associations and risk factors, characterizing the patterns of VF loss, defining the structure–function relationship of glaucoma, enhancing early diagnosis or earlier detection of progression, informing clinical decisions, and improving clinical trials. …”
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Attack traffic allocation and load balancing mechanism for SDN by LI Man, ZHOU Huachun, XU Qi, DENG Shuangxing, ZOU Tao, ZHANG Ruyun

“…The traffic allocation problem was modeled as a Markov decision process (MDP), where the reward function included both resource consumption and delay. …”
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Soil pollution and remediation: emerging challenges and innovations by Hao Chen, Bin Gao, Yuncong Li

“…These pollutants pose severe risks to environmental health and agricultural productivity by altering soil functionality and contaminant mobility. This perspective summarizes innovative monitoring and remediation technologies, including advanced sensors and bioremediation strategies, that enable real-time detection and effective management of soil pollutants. …”
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EZSCAN for undiagnosed type 2 diabetes mellitus: A systematic review and meta-analysis. by Antonio Bernabe-Ortiz, Andrea Ruiz-Alejos, J Jaime Miranda, Rohini Mathur, Pablo Perel, Liam Smeeth

“…<h4>Objectives</h4>The EZSCAN is a non-invasive device that, by evaluating sweat gland function, may detect subjects with type 2 diabetes mellitus (T2DM). …”
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Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice by Jun Yao, Nan Chen, Xiaojing Wang, Leisheng Zhang, Jiali Huo, Ying Chi, Zongjin Li, Zhongchao Han

“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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Multiwavelength Constraints on the Local Black Hole Occupation Fraction by Colin J. Burke, Priyamvada Natarajan, Vivienne F. Baldassare, Marla Geha

“…We also constrain the extremely low-luminosity end ( L _bol ≲ 10 ^40 erg s ^−1 ) of the active galactic nucleus (AGN) luminosity functions at z = 0. Our AGN luminosity functions are broadly consistent with an extrapolation of the shallow slope of the AGN luminosity functions from previous work.…”
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Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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Fast-timing spectroscopy with the ν-ball2 spectrometer by Pascu S., Hiver C., Podolyák Zs., Regan P.H., von Tresckow M., Wilson J.N.

“…These observables and their corresponding transition probabilities are key fingerprints for the structure of atomic nuclei, as they are sensitive to small components of the wave function. Neutron-rich nuclei have been populated in a two-step fission-induced experiment. …”
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Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible by Qingge Guo, Xiuxiu Jin, Xiaoyu Xin, Xiaohong Guo, Shuai Ming, Yuxiang Li, Bo Lei

“…Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. This study aims to reveal the multimodal imaging manifestations of DWP in high myopia and to explore its impact on retinal function. …”
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Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes by Ma L, Zheng E, Fang Y, Chen H, Zhou C, Cai S, Luo F, Jiang W, Wang J, Ning X, Tu H, Yin Z

“…IC spans five function domains: Locomotor, psychological, cognitive, vitality, and sensory (including vision and hearing). …”
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BioFire FilmArray Meningitis/Encephalitis Panel Utilised for the Unsolved Cases of Meningitis/Encephalitis: A Cross-sectional Study by Bashir Ahmad Fomda, Sanam Rasool Wani, Irfan Ul Haq, Anjum Ara, Gulnaz Bashir, Shugufta Roohi, Sheikh Imtiyaz, Naseer Ahmad Bhat

“…Introduction: Syndrome-based diagnosis of various infections is increasingly important. Even in resource-limited countries, adopting a syndrome-based method is essential, as Meningitis/Encephalitis (ME) can be caused by a multitude of agents that require detection through a multiplex assay. …”
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Consistent microbial insights across sequencing methods in soil studies: the role of reference taxonomies by Niranjana Rose Edwin, Aoife Duff, Coline Deveautour, Fiona Brennan, Florence Abram, Orla O'Sullivan

“…Our findings reveal that both methods offer moderately similar outcomes, providing consistent detection of major phyla, similar microbial community differentiation patterns, and largely identifying the same relationships between the phyla and nitrogen functions. …”
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