Heptad green metrics and quality by design tool evaluated chromatography method for content determination of Bexagliflozin in formulation product by Satyajit Raj Nethekar, Phani Raja Kanuparthy, Leela Prasad Kowtharapu, Vishnuvardhana Kishore Polisetti, Pankaj Kumar Lahoti, Sreekantha B Jonnalagadda, Naresh Kumar Katari

“…The study created an eco-friendly, rapid, sensitive, cost-efficient, stability-assessing method for analyzing Bexagliflozin in pharmaceuticals using a RP-UPLC approach. …”
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Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein Association to Extracellular Vesicles Using Lipid Anchors Enables High Loading and Effective Int... by Antonin Marquant, Jade Berthelot, Claudia Bich, Zeineb Ibn Elfekih, Laurianne Simon, Baptiste Robin, Joël Chopineau, David Tianpei Wang, Samuel Jay Emerson, Aijun Wang, Clément Benedetti, Simon Langlois, Laurence Guglielmi, Pierre Martineau, Anne Aubert‐Pouëssel, Marie Morille

“…By thoroughly characterising Lipid‐PEG‐protein anchorage, this study evidences the interest of this tunable and controllable approach for efficient EV protein delivery.…”
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Triple-E Principle: Leveraging Occam’s Razor for Dance Energy Expenditure Estimation by Kuan Tao, Kun Meng, Bingcan Gao, Junchao Yang, Junqiang Qiu

“…Conclusion: This study introduces a pioneering quantitative and unified model assessment system. Thoroughly analyzed and validated in the context of dance, the research offers detailed explanations of the most effective, efficient, and extensive models.…”
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Correlations between expression levels of genes encoding multifunctional YB-1 protein, inflammatory cytokines and multidrug resistance P-gp protein in surgical material from patien... by M. V. Erokhina, E. N. Pavlova, E. A. Scherbakova, E. Yu. Rybalkina, L. N. Lepekha, R. V. Tarasov, E. K. Tarasova

“…Gene expression was determined by quantitative PCR in the samples obtained at surgery from 35 patients. …”
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Anomaly Field Extraction Based on Layered-Earth Model and Equivalent Eddy Current Inversion: A Case Study of Borehole zk506 in Baishiquan, Xinjiang by Yi Yang, Jie Zhang, Qingquan Zhi, Yang Ou, Xingchun Wang, Lei Wang, Junjie Wu, Xiaohong Deng

“…Based on the concept of an equivalent eddy current, anomaly field inversion provides an efficient and rapid inversion method for borehole transient electromagnetic (BHTEM) measurements. …”
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Poly-ε-caprolactone/chitosan/whitlockite electrospun bionic membrane conjugated with an E7 peptide for bone regeneration by Guangzi Chen, Tao Xu, Ran Gao, Wenbin Liu, Weigang Li, Delu Zeng, Jian Li, Xuan Fang, Gaohong Sheng, Hongqi Zhao, Chaoxu Liu

“…The expression of osteogenesis related genes and angiogenesis associated genes were detected using quantitative real-time polymerase chain reaction (qRT-PCR). …”
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Exploration of plasma exosomal miR-122-5p and its related targets KNG1 and C3 in the diagnosis of drug-resistant tuberculosis by Xinyi Yao, Lahong Zhang

“…The RNA level of the miR-122-5p gene in plasma exosomes was detected by real-time fluorescence quantitative PCR (qRT-PCR). The KNG1 level in the plasma of the subjects was measured by ELISA, and the clinical indicators of the patients were also collected. …”
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Enhanced membrane protein production in HEK293T cells via ATF4 gene knockout: A CRISPR-Cas9 mediated approach by Byung-Jo Choi, Ba Reum Kim, Ho Joong Choi, Ok-Hee Kim, Say-June Kim

“…Compared to wild-type cells, ATF4-KO cells exhibited a significant increase in membrane protein production, with a 52.2 ± 19.0% improvement. Gene editing efficiency was compared between the two delivery systems, with the two-vector system demonstrating higher efficiency based on T7E1 assays. …”
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Applications of machine learning in potentially toxic elemental contamination in soils: A review by Yan Li, Bao Xiang, Tianyang Wang, Yinhai He, Xiaoyang Liu, Yancheng Li, Shichang Ren, Erdan Wang, Guanlin Guo

“…From these findings, ML techniques, through their powerful data processing capabilities, provide new perspectives and tools for the efficient assessment and management of soil PTEs contamination.…”
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A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions by Wataru Kitagawa, Wataru Kitagawa, Kensuke Igarashi, Ryo Nagasawa, Shigeyuki Kakizawa, Mizuki Horino, Kosuke Fujishima, Kosuke Fujishima, Toshiaki Fukui, Souichiro Kato, Souichiro Kato, Souichiro Kato

“…This advancement lays the groundwork for more efficient CO2-based biomanufacturing platforms, contributing to the development of sustainable bioprocesses.…”
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AlphaBind, a domain-specific model to predict and optimize antibody–antigen binding affinity by Aditya A. Agarwal, James Harrang, David Noble, Kerry L. McGowan, Adrian W. Lange, Emily Engelhart, Miranda C. Lahman, Jeffrey Adamo, Xin Yu, Oliver Serang, Kyle J. Minch, Kimberly Y. Wellman, David A. Younger, Randolph M. Lopez, Ryan O. Emerson

“…These models enable efficient in silico prescreening and optimization of antibody candidates. …”
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CC-Former: Urban Flood Mapping from InSAR Coherence with Vision Transformer: Libya and Storm Daniel as Test Case by T. Saleh, T. Saleh, T. Saleh, S. Holail, M. Al-Saad, F. Xu, M. Zahran, G.-S. Xia, G.-S. Xia

“…We conclude that the CC-Former model offers a promising solution for accurate and efficient urban flood mapping from InSAR coherence, with the potential for rapid generalization to other affected areas. …”
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Closing Gaps in Chronic Kidney Disease Detection: Evaluating At-Home Targeted Testing in a Safety-Net Population by Megan Schultz, Katelyn Laue, Nicole Bryer, Andrew Bzowyckyj, Anuja Java, Leslie Lake, Elizabeth Talbot-Montgomery, Brit Sovic, Bri’Anna Watson, Joseph A. Vassalotti

“…Methods: Through electronic health record (EHR) data analysis, eligible patients were identified to receive an at-home, semi-quantitative urine albumin-creatine ratio (uACR) testing kit. …”
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The value of using patient‐reported outcomes for health screening during long‐term follow‐up after paediatric stem cell transplantation for nonmalignant diseases by Joëll E. Bense, Nicole Guilonard, Femke Zwaginga, Anne M. Stiggelbout, Marloes Louwerens, Hilda Mekelenkamp, Arjan C. Lankester, Arwen H. Pieterse, Anne P. J. dePagter

“…Additionally, an explorative quantitative approach with patient‐reported experience measures (PREMS) was used, with a pretest–posttest design, to assess whether the use of PROs was accompanied by more patient‐centred care. …”
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Transfer learning and single-polarized SAR image preprocessing for oil spill detection by Nataliia Kussul, Yevhenii Salii, Volodymyr Kuzin, Bohdan Yailymov, Andrii Shelestov

“…The preprocessing technique normalizes SAR intensity values and encodes extracted features into RGB channels.Through an experiment, we have shown that a combination of the LinkNet with an EfficientNet-B4 is superior to pairs of other well-known architectures and encoders.Quantitative evaluation revealed a significant improvement in F1-score of 0.064 compared to traditional dB-scale preprocessing methods. …”
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Acceptability of self-administered acupressure for knee osteoarthritis in middle-aged and older adults: A mixed-method secondary analysis by Shu-Cheng Chen, Nicole Nok Leung, Hui-Lin Cheng, Min-Ru Wu, Denise Shuk-Ting Cheung, Jia-Yin Ruan, Jing Qin, Ge Ren, Wing-Fai Yeung

“…Future research should focus on optimizing intervention implementation by providing professional support and efficient monitoring to address identified challenges.…”
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Additive Manufacturing and Chemical Engineering: Looking for Synergies from a Bibliometric Study by Rodrigo Estévez, Esteban Quijada-Maldonado, Julio Romero, Ricardo Abejón

“…Despite its significant potential, research compiling and evaluating the specific contributions of additive manufacturing in the field of chemical engineering was scarce in both quantitative and qualitative terms. Similarly, the application of chemical engineering tools to additive manufacturing has not been specifically reviewed. …”
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CRISPR-Cas12a/Aurora Deoxyribozyme Cascade: A Label-Free Ultrasensitive Platform for Rapid <i>Salmonella</i> Detection by Cong Shi, Huimin Tan, Zhou Yu, Weilin Li, Yan Man, Qinghai Zhang

“…This cascade ultimately enables quantitative target analysis through fluorescence signal attenuation. …”
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Developing an Operational Approach to Educational Quality Assurance in Colleges under the Office of the Vocational Education Commission in Thailand by Ch. Chianchana, S. Na Wichian

“…This method of analysis can be used to respond to educational quality assurance policy that requires that the demonstrated approach is to be easily applied in practice and requires the use of both quantitative and qualitative methods, thus creating innovations in the field of productivity-enhancing and their application in vocational education. …”
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Sustainable science or business as usual? Exploring awareness and actions in German University Laboratories by Caterina Baars, Patrycja Karwasiecka, João Henrique Paulino Pires Eustachio, Andrea Dobri, Jelena Barbir, Sven Kannenberg, Walter Leal Filho

“…For this purpose, a mixed-method approach was applied, consisting of a quantitative survey answered by 81 laboratories, and a qualitative interview conducted within 9 different universities. …”
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