The use of “Acellbia” – a biosimilar of rituximab in systemic sclerosis by L. P. Ananyeva, L. A. Garzanova, O. V. Desinova, R. U. Shayakhmetova, M. N. Starovoytova, O. A. Koneva, O. B. Ovsyannikova, S. I. Glukhova, E. L. Nasonov

“…Indications for the prescribing of ACB were high disease activity and the presence of risk factors for progression. All patients had radiological signs of interstitial lung disease, 13 (65%) were positive for antibodies to topoisomerase 1. …”
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Interferon Gamma and Tumor Necrosis Factor Alpha Are Inflammatory Biomarkers for Major Adverse Cardiovascular Events in Patients with Peripheral Artery Disease by Ben Li, Eva Lindner, Raghad Abuhalimeh, Farah Shaikh, Houssam Younes, Batool Abuhalimeh, Abdelrahman Zamzam, Rawand Abdin, Mohammad Qadura

“…Inflammatory proteins play a key role in the progression of atherosclerosis and may serve as useful prognostic indicators for systemic cardiovascular risk in PAD. …”
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Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease by Nicole Welch, Pugazhendhi Kannan, Saurabh Mishra, Annette Bellar, Vandana Agrawal, Grahame Kidd, Emily Benson, Ryan Musich, Raya Tabbalat, Ling Li, J. Mark Brown, Belinda Willard, Karyn A. Esser, Laura E. Nagy, Srinivasan Dasarathy

“…These findings show the complex molecular interactions leading to mitochondrial dysfunction and progressive sarcopenia in ALD.…”
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Associations of the Neutrophil-to-Lymphocyte Ratio(NLR), Triglyceride-Glucose Index (TyG), and TyG-derived indices with vitality decline in older adults in China: a study within th... by Jiaxiu Zhao, Xueying Ji, Yixin Chen, Jiaofeng Wang, Jie Chen, Yiqin Huang, Zhijun Bao

“…Three logistic regression models constructed with progressive adjustments were used to assess associations between indices (NLR, TyG, TyG-WC, TyG-BMI, and TyG-WHtR) and vitality decline. …”
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Gait parameters and daily physical activity for distinguishing pre-frail, frail, and non-frail older adults: A scoping review by Xin Zhang, Feng Li, Hans SM Hobbelen, Barbara C van Munster, Claudine JC Lamoth

“…Walking variation identified pre-frail status, showing progressive decreases from non-frail to frail states. …”
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Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocard... by Yu-jiao Song, Xiao-ying Zhao, Lu-jing Wang, Ting Ning, Ming-tian Chen, Pei Liu, Si-wen Chen, Xin-xiang Zhao

“…Abstract Background and purpose Epicardial adipose tissue (EAT) comprises three distinct lipid components, each exerting differential effects on cardiovascular diseases. During disease progression, dynamic alterations in lipid composition and spatial distribution contribute to the inherent heterogeneity of EAT. …”
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Comprehensive Analysis of the Expression, Prognosis and Function of TRAF Family Proteins 
in NSCLC by Yixuan WANG, Qiang CHEN, Yaguang FAN, Shuqi TU, Yang ZHANG, Xiuwen ZHANG, Hongli PAN, Xuexia ZHOU, Xuebing LI

“…However, the exact mechanisms underlying lung cancer progression remain unclear. The tumor necrosis factor receptor associated factor (TRAF) family members are cytoplasmic adaptor proteins, which function as both adaptor proteins and ubiquitin ligases to regulate diverse receptor signalings, leading to the activation of nuclear factor kappa-B (NF-κB), mitogen-activated protein kinase (MAPK) and interferon regulatory factor (IRF) signaling. …”
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Acute Care Practice in the United States: The Roles of Occupational Therapy and Physical Therapy in Early Rehabilitation by Suzanne E. Holm, Kelly Nelson, Angela Patterson

“…In PT, the emphasis is on promoting and progressing patients'mobility and movement to increase performance and to enhance function, well-being, overall health and quality of life. …”
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EFFECTS OF SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUGS, BIOLOGICAL AGENTS, AND PSYCHOPHARMACOTHERAPY ON THE MENTAL DISORDERS IN PATIENTS WITH RHEUMATOID ARTHRITIS by A. A. Abramkin, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, E. L. Nasonov

“…Synthetic DMARDs had no effect on the ADS disorders and CI in patients with RA; BAs promoted the regression of ADs and did not affect the progression of depression and CI. A combination of DMARDs and BAs used at the adequate dose of PPDs for the same period led to the regression of ADS disorders and the reduction in the frequency of CI.…”
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Lactato y fuerza muscular como indicadores de eficacia del entrenamiento en población con riesgo cardíaco(Lactate and muscle strength as indicators of training effectiveness in pop... by Mauro Tauda, Eduardo Cruzat Bravo, Felipe Suárez Rojas

“…They performed two strength tests in the average squat, the first progressive to the anaerobic threshold, from which the average load of the results was obtained that was used in the second test, where 15 series of 15 repetitions were performed with 1 minute rests between. each series. …”
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Validación de la prueba de denominación de animales para el diagnóstico de la encefalopatía hepática mínima by A.D. Cano-Contreras, J.A. Velarde-Ruiz Velasco, F. Higuera-de-la-Tijera, C.F. Castillo-Diaz, D. Grajales-Velázquez, I. Méndez-Ruiz, V.A. Jiménez-Hernández, R. Aguirre-Lázaro, J.A. Sánchez-Hernández, H.R. Ordaz-Álvarez, J.M. Remes-Troche

“…In our population, a cutoff point ≤ 15 animals named could be utilized for rapid screening of patients at high risk for progressing to overt HE, who would then require extensive testing.…”
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TyG-BMI as a predictor of ischemic stroke over 10 years in middle-aged and older adults: findings from the China cardiometabolic disease and cancer cohort (4C) study by Ying Miao, Ying Miao, Ying Miao, Ying Miao, Ying Miao, Yu Wang, Yuting He, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan

“…Research has demonstrated that insulin resistance (IR) plays a key role in the development of atherosclerosis, platelet dysfunction, and a hypercoagulable state, all of which contribute to the pathogenesis and progression of IS. The triglyceride-glucose (TyG) index serves as a practical tool for assessing insulin sensitivity, with previous studies exploring its correlation with IS. …”
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A survey of knowledge about health education and self-management behavior in 118 patients with early diabetic nephropathy (118例早期糖尿病肾病患者健康教育知识水平及自我管理行为现状调查)... by CHEN Furong (陈芙蓉), ZHOU Jianping (周建平), MAO Dandan (毛丹旦), BO Jing (薄静), ZHUANG Ji (庄姬)

“…In addition, the poor self-management behavior among patients with early diabetic nephropathy may indicate poor diabetes self-management as a negative influencing factor of progression of early diabetic nephropathy. (目的 探讨早期糖尿病肾病患者健康教育知识水平及自我管理行为现状, 为制定针对性的健康教育及护理方案提供依据。…”
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Modified Сomplex Treatment of the Cirhotic Patients with the Hepatopulmonary Syndrome of the Different Severity Degrees: Pathogenetic Reasoning and Efficiency by Abrahamovych M., Abrahamovych O., Tolopko S., Ferko M.

“…During the study of some pathogenetic mechanisms of the HPS it was found the inverse correlative connection between the values of carbon dioxide partial pressure, bicarbonate, standard bicarbonate, bases excess in the blood and in the extracellular fluid and the severity of the HPS, which was manifested by the progressive metabolic acidosis that required the medical correction. …”
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Validation of the animal naming test for diagnosing minimal hepatic encephalopathy by A.D. Cano-Contreras, J.A. Velarde-Ruiz Velasco, F. Higuera-de-la-Tijera, C.F. Castillo-Diaz, D. Grajales-Velázquez, I. Méndez-Ruiz, V.A. Jiménez-Hernández, R. Aguirre-Lázaro, J.A. Sánchez-Hernández, H.R. Ordaz-Álvarez, J.M. Remes-Troche

“…In our population, a cutoff point ≤15 animals named could be utilized for rapid screening of patients at high risk for progressing to overt HE, who would then require extensive testing. …”
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Variability of CO₂ and CH₄ in a coastal peatland rewetted with brackish water from the Baltic Sea derived from autonomous high-resolution measurements by D. L. Pönisch, D. L. Pönisch, H. C. Bittig, M. Kolbe, I. Schuffenhauer, S. Otto, P. Holtermann, K. Premaratne, G. Rehder

“…This was potentially due to a progressive consumption of organic material, a suppression of CH<span class="inline-formula">₄</span> production, and aerobic and anaerobic oxidation of CH<span class="inline-formula">₄</span>, indicating a positive evolution of the rewetted peatland into a site with moderate GHG emissions within the next years.…”
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Coastal Storm – Surge Combination Risk Identification and Resilience Planning Based on Supply and Demand Assessment of Flood Regulation Ecosystem Services: A Case Study of Fujian D... by Jian TIAN, Tianyu XIU, Suiping ZENG

“…Benefiting from the region’s favorable ecological conditions, inland zones generally exhibit a stronger capacity for flood regulation, with service provision increasing progressively from the coastal fringes to the interior. …”
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Damage Strength Model of Soil–Structure Interface Based on Equivalent Damage by Huaixin LI, Changgen YAN, Jiale XIE, Weifeng SUN, Yuling SHI, Zhuolong JIA

“…This model effectively fits the nonlinear relationship at the soil-structure interface under different soil shear area ratios, making it suitable for programmed calculations in finite element software.…”
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Epidemiological evidence for a hereditary contribution to myasthenia gravis: a retrospective cohort study of patients from North America by Joel Oger, Joshua D Green, Bryan J Traynor, Richard J Barohn, Michael Benatar, Emanuela Bartoccion, Derrick Blackmore, Vinay Chaudhry, Manisha Chopra, Andrea Corse, Mazen M Dimachkie, Amelia Evoli, Julaine Florence, Miriam Freimer, James F Howard, Theresa Jiwa, Henry J Kaminski, John T Kissel, Wilma J Koopman, Bernadette Lipscomb, Michelanglo Maestri, Mariapaola Marino, Janice M Massey, April McVey, Michelle M Mezei, Srikanth Muppidi, Michael W Nicolle, Robert M Pascuzzi, Mamatha Pasnoor, Alan Pestronk, Carlo Provenzano, Roberta Ricciardi, David P Richman, Julie Rowin, Donald B Sanders, Zaeem Siddiqi, Aimee Soloway, Gil I Wolfe, Charlie Wulf, Daniel B Drachman

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Leveraging infant visit PrEP screening INtegration & tasK shifting to improve post-partum HIV prevention in Malawi (LINK): a cluster-randomized trial evaluation of a postpartum HIV... by Sarah E. Rutstein, Valerie A. Lucas, Mina C. Hosseinipour, Michael E. Herce, Jessie Edwards, Caitlin Cassidy, Jimmy Villiera, Funny Kamanga, Maganizo Chagomerana, Joep J. van Oosterhout, Elijah Chikuse, Ethel Rambiki, Agness Thawani, Bridget Malewezi, Lazola Makhupula, Clement Udedi, Patrick Mbulaje, Mitch Matoga, Wiza Kumwenda, Tisungane Mvalo, Agatha Bula, Lovemore Nkhalamba, Innocent Mofolo, Lameck Chinula, Virginia Thonyiwa, Owen Kumwenda, Mike Nenani Chisema, Irving F. Hoffman, William C. Miller, Vivian F. Go, Brian Pence, Madeleine A. Squibb, Friday Saidi

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