Effect of CYP3A4/5, ABCB1 gene polymorphisms on the residual equilibrium concentration of apixaban and bleeding in patients with non-valvular atrial fibrillation and deep vein thro... by l. V. Fedina, i. N. Sychev, K. V. Mirzaev, A. V. Vardanyan, S. V. Glagolev, A. A. Kachanova, P. O. Bochkov, R. V. Shevchenko, S. N. Tuchkova, I. V. Sychev, S. P. Abdullaev, D A. Sychev

“…Statistical processing was performed in SPSS Statistics 20.0 program.Results. We found that patients with CT ABCB1 (rs4148738) C>T genotype had higher Cmin,ss /D value than patients with TT genotype (6.23 [4;13] vs 5.77 [4;17], p=0.018). …”
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iCogCA to Promote Cognitive Health Through Digital Group Interventions for Individuals Living With a Schizophrenia Spectrum Disorder: Protocol for a Nonrandomized Concurrent Contro... by Christy Au-Yeung, Helen Thai, Michael Best, Christopher R Bowie, Synthia Guimond, Katie M Lavigne, Mahesh Menon, Steffen Moritz, Myra Piat, Geneviève Sauvé, Ana Elisa Sousa, Elisabeth Thibaudeau, Todd S Woodward, Martin Lepage, Delphine Raucher-Chéné

“…Technology did not appear to significantly impede program participation. Therapist-rated levels of engagement were also satisfactory. …”
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Quantitative release assessment for beta-lactamase-producing Escherichia coli of dairy origin into vegetables by Kohei Makita, Dongsheng Zhang, Ayaka Okamura, Akira Fukuda, Natsumi Tokunaga, Tetsuo Asai, Yoko Shimazaki, Masaru Usui

“…Data on the indicated diseases and antimicrobial use in dairy cattle were obtained from the agricultural insurance program in Hokkaido Prefecture between 2016 and 2019. …”
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Effects of photosymbiosis and related processes on planktic foraminifera-bound nitrogen isotopes in South Atlantic sediments by A. Auderset, A. Auderset, S. M. Smart, Y. Ryu, D. Marconi, H. A. Ren, L. Heins, H. Vonhof, R. Schiebel, J. Repschläger, D. M. Sigman, G. H. Haug, A. Martínez-García

“…We report new glacial–interglacial foraminifera-bound <span class="inline-formula"><i>δ</i>¹⁵</span>N (FB-<span class="inline-formula"><i>δ</i>¹⁵</span>N) data from Deep Sea Drilling Program Site 516, located in the subtropical South Atlantic gyre, which contains multiple foraminifera species at adequately high abundance for interspecies comparison of foraminiferal nitrogen, carbon, and oxygen isotopes over a full glacial cycle. …”
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Defining Health Movements and Health Needs Across the Life Course: A Qualitative Study by Alyssa Yenyi Chan, Felicia Jia Hui Chan, Lucas Jia Rong Puah, Muhammad Bin Aman Azamuddin, Priyanka Rajendram, Weng Mooi Tan, Yoek Ling Yong, Zoe Jane‐Lara Hildon

“…Community Movement Champions [CMCs]) and the M4H administrating committee to inform future programming. Future CMCs have taken up the recommendations extracted from stakeholder engagement, where components on sleep, mental health, etc., have been added. …”
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Mesenchymal stem cells derived from hPSC via neural crest attenuate chemotherapy-induced premature ovarian insufficiency by ameliorating apoptosis and oxidative stress in granulosa... by Xinran Li, Jinrong Liao, Youhong Zheng, Wei Cai, Jie Chen, Yu Liang, Yuanmei Chen, Xiaoxuan Li, Jiamao Luo, Jiaxin Xie, Manping Zhou, Lilin Hang, Xiujuan Sun, Xin Yue, Xuefeng Wang, Yifeng Wang, Huiyan Wang

“…Results Our optimized protocol, combining CHIR99021 and SB431542, efficiently induced NCC from both human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC). The programmed hPSC-NCC-MSC, characterized by specific NCC markers (P75, HNK1, SOX10, and AP2α), exhibited typical MSC morphology, trilineage differentiation potential, favorable cell viability, and prominent anti-senescence properties. …”
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Efficacy and safety of neoadjuvant sintilimab, oxaliplatin and capecitabine in patients with locally advanced, resectable gastric or gastroesophageal junction adenocarcinoma: early... by Yan Wang, Ning Li, Jing Zhang, Ying Liu, Zhongqi Li, Nong Xu, Zhimin Ma, Yafei Zhang, Haiping Jiang, Xiongfei Yu, Mei Kong, Donghui Zhou, Weibin Wang, Haohao Wang, Haiyong Wang, Kuifeng He, Yimin Lu, Kui Zhao, Ziran Li, Yisen Wang, Lisong Teng

“…However, the role of anti-programmed cell death protein-1 treatment in the neoadjuvant setting remains unclear. …”
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Balance of CD4⁺IFNγ+ and CD4⁺CD25^hiT cells as early predictor of a 3-month outcome in ischemic stroke patients by S. A. Morozov, M. A. Tikhonova, N. V. Pronkina, A. A. Shtobbe, O. Yu. Leplina, E. Ya. Shevela, A. A. Ostanin, E. R. Chernykh

“…Early prediction for ischemic stroke (IS) outcome is a major challenge since it may help to optimize treatment program and  to make  it more  personalized. Since  T cells with  regulatory activity  are involved  in different  pathophysiological processes  in brain  stroke,  including inflammation, immune suppression, brain damage  and  repair, the  study  of T cells as potential biomarkers has essential  importance. …”
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Life cycle greenhouse gas emissions of conventional and alternative steel production methods in countries dependent on energy import: A South Korean case study by Juha Lee, Gyuna Kwak, Yujin Jung, Wonjae Choi

“…The analysis employed the GREET program developed by the Argonne National Laboratory in the United States, modified and expanded to reflect the Korean context. …”
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Impact of Institutional Monthly Volume of Transcatheter Edge-to-Edge Repair Procedures for Significant Mitral Regurgitation: Evidence from the GIOTTO-VAT Study by Nicola Corcione, Paolo Ferraro, Filippo Finizio, Michele Cimmino, Michele Albanese, Alberto Morello, Giuseppe Biondi-Zoccai, Paolo Denti, Antonio Popolo Rubbio, Francesco Bedogni, Antonio L. Bartorelli, Annalisa Mongiardo, Salvatore Giordano, Francesco De Felice, Marianna Adamo, Matteo Montorfano, Francesco Maisano, Giuseppe Tarantini, Francesco Giannini, Federico Ronco, Emmanuel Villa, Maurizio Ferrario, Luigi Fiocca, Fausto Castriota, Angelo Squeri, Martino Pepe, Corrado Tamburino, Arturo Giordano

“…These findings inform on the importance of operator experience and center expertise in achieving state-of-the-art results with TEER, while confirming the usefulness of the proctoring approach when naïve centers begin a TEER program.…”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…This investigation was conducted within the framework of the interdisciplinary scientific program «Stress factors and mental disorders in rheumatic diseases». …”
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Teleconsultation for infectious disease management in pediatric intensive care by Dr Jacopo Ceradini, MD Daniela Perrotta, MD Elio Tamburello, MD Marcella Aversa, MD Laura Lancella, MD Francesca Ippolita Calò Carducci, MD Maia De Luca, MD Lorenza Romani, Carmen D'amore, Gaetano Ciliento, Leonardo Vallesi, Massimiliano Raponi, MD Marta Luisa Ciofi degli Atti

“…Conclusion: Teleconsultation contributed to reducing antibiotic consumption in PICU suggesting its effectiveness in the multidisciplinary management of PICU patients within an antimicrobial stewardship program.…”
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Efficacy and safety of Tofacitinib in patients with active rheumatoid arthritis resistant to conventional therapy: Preliminary results of an open-label clinical trial by E. L. Luchikhina, D. E. Karateev, N. V. Demidova, A. S. Musiyuk, E. N. Aleksandrova, A. A. Novikov, A. V. Smirnov, E. L. Nasonov

“…This ongoing open-label trial is a part of the scientific program «Russian Investigation of Methotrexate and Biologics in Early Active Inflammatory Arthritis» (REMARCA) that explores the possibility of adapting the «treat-to-target» strategy in real prac-tice in Russia. …”
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Agronomic Performance of Newly Developed Elite Cowpea Mutant Lines in Eswatini by Kwazi A. K. Mkhonta, Hussein Shimelis, Seltene Abady, Asande Ngidi

“…The following traits, NPP, NSP, PDL, GYD, and HSW, offered unique opportunities for genotype selection in the cowpea breeding program in Eswatini.…”
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Effects of maternal blood beta-hydroxybutyrate on brown adipose tissue functions and thermogenic and metabolic health in neonatal calves by Yang Gai, Guiling Ma, Shuyan Yang, Zhiyong Hu, Yulin Ma, Rui He, Yu Zhang, Shilong Huang, Hossam H. Azzaz, Zhaobing Gu, Shengyong Mao, Morteza H. Ghaffari, Yanting Chen

“…Overall, this study demonstrates that calves born from elevated maternal BHB levels (∼0.64 mM) within the normal physiological range in the dry period significantly had impaired perinatal BAT development, thermogenesis, and glucose metabolism, highlighting the roles of maternal metabolic health in programming metabolic and thermoregulatory capacity in offspring.…”
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Colchicine for preventing stroke in patients with and without intracranial atherosclerotic stenosis: a prespecified analysis of a randomized clinical trialResearch in context by Jiejie Li, Jing Jing, Xia Meng, Fu-Dong Shi, Hong-Qiu Gu, Aoming Jin, Yong Jiang, Hao Li, S. Claiborne Johnston, Graeme J. Hankey, J. Donald Easton, Xuewei Xie, Wei-Na Jin, Liguo Chang, Penglai Shi, Lihua Wang, Xianbo Zhuang, Haitao Li, Yingzhuo Zang, Jianling Zhang, Zengqiang Sun, Dongqi Liu, Ying Li, Hongqin Yang, Jinguo Zhao, Weiran Yu, Anxin Wang, Yuesong Pan, Jinxi Lin, Shuya Li, Siying Niu, Yilong Wang, Xingquan Zhao, Zixiao Li, Liping Liu, Huaguang Zheng, Yongjun Wang, Xingquan Zhao, Liguo Chang, Minghua Cao, Yanliang Miao, Dali Li, Xiafeng Yang, Aimei Wu, Penglai Shi, Jianghua Si, Hongqin Yang, Naian Xiao, Na Guo, Ling Ma, Youren Li, Tianming Pan, Yingzhuo Zang, Fangqi Tian, Youjun Liu, Xiaopeng Feng, Dongqi Liu, Xianwen Han, Yi Zhao, Xueling Zhang, Mei Hong, Airen Lu, Haichao Liu, Zhonghai Jia, Kai Li, Xiaosong Li, Ziyan Li, Dongli Chen, Lifeng Lei, Jingwen Jiao, Baohua Zhao, Peiduo Yuan, Xingchi Wang, Qiang Li, Jianmin Guo, Xin Wang, Cunrui Wang, Haifeng Huang, Yanhua Zhang, Yefang Feng, Baojun Wang, Weifeng Lu, Huqing Li, Bojun Han, Jianghuan Zheng, Jianhua Li, Hongtian Zhang, Yu Che, Yuhai Liu, Jianli Cheng, Ni Wang, Yunshu Zhang, Dongyun Li, Dongwei Zhang, Haitao Li, Baolong Wang, Xintong Liu, Tianhui He, Duanling Ye, Ping Sun, Anqiang Chen, Weimin Hong, Hongbin Liang, Yanqiu Du, Jinguo Zhao, Min Zhang, Weifeng Chen, Xiting Zhang, Hongguo Dai, Junfeng Shi, Ke Li, Junfeng Zhao, Qian Wang, Yuqing Zhang, Yajun Liu, Xiangming Wang, Bin Li, Bingqi Zhang, Xiaomin Mei, Mingqing Zhen, Jinhui Qin, Yanling Hu, Cunju Guo, Li Ji, Zengqiang Sun, Yunyi Dai, Yong You, Bo Wang, Changhao Jiang, Rong Zou, Runting Jing, Di Pu, Pida Hao, Defeng Tian, Qian Xue, Zhigang Liang, Aisheng Wu, Jingya Jiao, Wei Wu, Dong Wang, Zhen Jiao, Jianping Niu, Xiangbin Wu, Jing Wang, Ping Shen, Zhao Li, Huihai Du, Liqin He, Xinhui Kou, Jing Chen, Quping Ouyang, Youquan Ren, Chunjie Yang, Hailian Jin, Yongming Chen, Chunlei Li, Qiuwu Liu, Hongliang Wang, Hao Hu, Ying Li, Gongping Zhu, Shaofa Li, Hongyun Chang, Huixiang Tang, Sumin Bai, Weidong Jia, Wensheng Tian, Shuzhen Yang, Zhenhua Xi, Degang Sun, Can Jiang, Yueqiang Gao, Xia Wei, Jianling Zhang, Rongfang Ma, Fujian Chen, Yanan Zhu, Hongjuan Chang, Houqin Chen, Guoyou Zhao, Junyong Zhao, Jing Ding, Shoucheng Zhang, Rui Wang, Panbing Huang, Jingyuan Jiang, Haipeng Li, Wei Zhang, Qingcheng Yang, Chen Niu, Ke Deng, Guoping Zou, Zhongfeng Yu, Yongqian Lei, Yan Wei, Tao Sun, Diwen Zhang, Hongliang Wang, Jiafeng Dong, Xinbo Deng, Dong Chen, Hongyan Ni, Lujun Zhang, Guofeng Li, Shifeng Guo, Dan He, Lie Wu, Guoqiang Yang, Ying Hai, Dongjing Song, Yan Han, Chaoqun Li, Li Wang, Xiue Wei, Runxiu Zhu, Haiyan Xu, Xinsheng Han, Wen Shangguan, Ailian Zhang, Jun Gu, Peng Guo, Hairong Sun, Baoguo Xue, Lihua Wang, Wanyong Yang, Shihao You, Mingjie Liu, Huijuan Sun, Anding Xu, Nengwei Yu, Yafei Shangguan, Lianmei Zhong, Xinqiang Wang, Hejun Chen, Juan Feng, Xiangqing Xu, Xiaoxuan Zhang, Jianguo Ge, Meirong Zhu, Dongbo Li, Jiajun Huang, Xiaoyan Li, Zhihui Duan, Weiying Di, Jianchao Qin, Fang Li, Guangming Kang, De Yang, Wenfeng Cao, Chunsheng Cai, Xiangqing Li, Yi Wang, Shengfu Yang, Xianghong Liu, Hebin Wan, Muhui Lin, Feng Wang, Ying Xing, Qiangyuan Tian, Wanying Li, Honghao Man, Zhihua Hao, Ziran Wang, Yanhua Zhou, Xinyi Li, Hong Chen, Hongyan Li, Junmei Wang, Jinfeng Shi, Dali Li, Juan Tang, Di Zhong, Bin Liu, Chuanzhen Qu, Haiying Wang, Chen Chen, Xiangyu Pu, Yukai Wang, Yangmei Chen, Yang Xu, Fei Wang

“…Funding: National Key R&D Program of China, National Natural Science Foundation of China, the Capital's Funds for Health Improvement and Research and Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences. …”
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The state of the biogeometric profile of the posture of young athletes specializing in hand-to-hand combat as a prerequisite for the development of corrective and preventive measur... by Vitalii Kashuba, Аndrii Radchenko, Yuri Radchenko, Ilia Vako, Vitaly Usychenko

“…The problems identified during the study were solved using generally accepted methods: theoretical analysis of scientific literature on the chosen research topic; the Torso program was used to determine the types of posture, visual screening of the state of the biogeometric profile of the posture of young athletes specializing in hand-to-hand combat included a focus on the tribal system and the use of a method for comparing individual posture on a photogram and methods of mathematical statistics. …”
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Experiences Receiving and Delivering Virtual Health Care For Women: Qualitative Evidence Synthesis by Karen M Goldstein, Sharron Rushton, Allison A Lewinski, Abigail Shapiro, Tiera Lanford-Davey, Jessica N Coleman, Neetu Chawla, Dhara B Patel, Katherine Van Loon, Megan Shepherd-Banigan, Catherine Sims, Sarah Cantrell, Susan Alton Dailey, Jennifer M Gierisch

“…Quality assessment was conducted using the Critical Appraisal Skills Program and certainty of evidence using Confidence in the Evidence from Reviews of Qualitative Research approaches. …”
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Estimating cardiovascular effects of influenza vaccination in older adults: a target trial emulation using proximal causal inferenceResearch in context by Jinxin Guo, Tiansheng Wang, Zhike Liu, Weihong Zeng, Peng Shen, Yexiang Sun, Siyan Zhan, Yang Xu

“…Funding: National Natural Science Foundation of China; Science and Technology Project of Science and Technology Bureau of Yinzhou District, Ningbo City; Zhejiang Provincial Centre for Disease Control and Prevention Science and Technology Program; Bill &amp; Melinda Gates Foundation.…”
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Mapping of quantitative trait loci and mining of candidate genes for seed viability in soybean [Glycine max (L.) Merr.] by Manisha Saini, Raju R. Yadav, Rahul Kumar, Rahul Kumar, Subhash Chandra, N. Krishna Kumar Rathod, Meniari Taku, Manu Yadav, Sudipta Basu, Ambika Rajendran, S. K. Lal, Akshay Talukdar

“…Understanding inheritance and mapping of quantitative trait loci (QTLs) for seed viability would help in designing breeding program for developing varieties with higher viability of the seeds. …”
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