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    In Silico and In Vitro development of novel small interfering RNAs (siRNAs) to inhibit SARS-CoV-2 by Noha Samir Taibe, Sara H. Mahmoud, Maimona A. Kord, Mohamed Ahmed Badawy, Mahmoud Shehata, Mahmoud Elhefnawi

    Published 2025-01-01
    “…Our design strategy for siRNAs differs from existing studies through a step-by-step filtration process utilizing integrative bioinformatics protocols and web tools. …”
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    Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity by Amy Dashwood, Ntombizodwa Makuyana, Rob van der Kant, Arman Ghodsinia, Alvaro R. Hernandez, Stephanie Lienart, Oliver Burton, James Dooley, Magda Ali, Lubna Kouser, Francisco Naranjo, Matthew G. Holt, Frederic Rousseau, Joost Schymkowitz, Adrian Liston

    Published 2025-01-01
    “…Here we use SolubiS and dTANGO, computational algorithm-based methods, to predict mutations within the IL2 structure to improve protein production yield in muteins with altered cellular selectivity, to generate combined muteins with elevated therapeutic potential. …”
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    Predicting student achievement through peer network analysis for timely personalization via generative AI by Ivica Pesovski, Petar Jolakoski, Vladimir Trajkovik, Zuzana Kubincova, Michael A. Herzog

    Published 2025-06-01
    “…Methods: Bi-weekly surveys were conducted throughout the academic year with 45 students enrolled in a computer science program, where students nominated up to five peers they collaborated with the most. …”
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