Mathematical modeling unveils the timeline of CAR-T cell therapy and macrophage-mediated cytokine release syndrome. by Daniela S Santurio, Luciana R C Barros, Ingmar Glauche, Artur C Fassoni

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Bayesian Inference of Pathogen Phylogeography using the Structured Coalescent Model. by Ian Roberts, Richard G Everitt, Jere Koskela, Xavier Didelot

“…The structured coalescent model has a long history of being used as the underlying process for such phylogeographic analysis. However, the computational cost of using this model does not scale well to the large number of genomes frequently analysed in pathogen genomic epidemiology studies. …”
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Research on the application of improved MCMC algorithm in the measurement of high-dimensional financial data by Naijia Liu, Yuchao Su

“…Moreover, it can significantly improve the computational efficiency and save the computational cost when dealing with financial time series containing high-frequency data.…”
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Breathing ferroelectricity induced topological valley states in kagome niobium halide monolayers by Kai-Qi Wang, Jun-Ding Zheng, Wen-Yi Tong, Chun-Gang Duan

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Model guided trait-specific co-expression network estimation as a new perspective for identifying molecular interactions and pathways. by Juho A J Kontio, Tanja Pyhäjärvi, Mikko J Sillanpää

“…Resulting trait-specific co-expression network estimation method 1) serves to enhance the interpretation of biological networks in a parametric sense, and 2) exploits the underlying parametric model itself in the estimation process. To also account for the substantial amount of intrinsic noise and collinearities, often entailed by expression data, a tailored co-expression measure is introduced along with this framework to alleviate related computational problems. …”
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Identification of hateful amharic language memes on facebook using deep learning algorithms by Mequanent Degu Belete, Girma Kassa Alitasb

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Shape-driven deep neural networks for fast acquisition of aortic 3D pressure and velocity flow fields. by Endrit Pajaziti, Javier Montalt-Tordera, Claudio Capelli, Raphaël Sivera, Emilie Sauvage, Michael Quail, Silvia Schievano, Vivek Muthurangu

“…Barriers for CFD include high computational resources, specialist experience needed for designing simulation set-ups, and long processing times. …”
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Blockchain-based inter-operator settlement system by Shifu Zhang, Yulin Pan

“…The framework achieves full-process traceability, automated reconciliation, and enhanced financial governance while reducing reliance on manual intervention. …”
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An artificial ecological system-based optimization to forecast the maximal TPH removal from Nigeria's Niger Delta crude oil-contaminated soil treated with a mix of biochar by Daniel Hogan Itam, Chimeme Martin Ekwueme, Ibiba Taiwo Horsfall

“…It is clear that AEO computed faster than the others in both cases of distinct upper boundaries.…”
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Model supports asymmetric regulation across the intercellular junction for collective cell polarization. by Katherine Levandosky, Calina Copos

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CNN-BiLSTM and DC-IGN fusion model and piecewise exponential attenuation optimization: an innovative approach to improve EEG emotion recognition performance by Shaohua Zhang, Yan Feng, Ruzhen Chen, Song Huang, Qianchu Wang

“…EEG emotion recognition has important applications in human-computer interaction and mental health assessment, but existing models have limitations in capturing the complex spatial and temporal features of EEG signals. …”
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Discovery of new high-pressure phases – integrating high-throughput DFT simulations, graph neural networks, and active learning by Ching-Chien Chen, Robert J. Appleton, Saswat Mishra, Kat Nykiel, Alejandro Strachan

“…Despite its importance, the process of finding new high-pressure phases, either experimentally or computationally, is time-consuming and often driven by intuition. …”
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Multi‐modal fusion attention sentiment analysis for mixed sentiment classification by Zhuanglin Xue, Jiabin Xu

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Bayesian exploration of the composition space of CuZrAl metallic glasses for mechanical properties by Tero Mäkinen, Anshul D. S. Parmar, Silvia Bonfanti, Mikko J. Alava

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Analysis of the effects of digital transformation of enterprise clusters on innovation performance in the context of “Internet+” by Sumei Zeng, Jinding Bao

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Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses. by Andres Kriete, William J Bosl, Glenn Booker

“…Investigating the complex systems dynamics of the aging process requires integration of a broad range of cellular processes describing damage and functional decline co-existing with adaptive and protective regulatory mechanisms. …”
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Application of preoperative registration and automatic tracking technique for image-guided maxillofacial surgery by Wenbin Zhang, Xudong Wang, Jianfei Zhang, Guofang Shen

“…The accuracy of registration process was determined, and the deviation between planning model and postoperative computed tomography (CT) model was detected.Results: In each case, the preoperative registration was successful for navigational surgery. …”
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Prediction of gene expression in embryonic structures of Drosophila melanogaster. by Anastasia A Samsonova, Mahesan Niranjan, Steven Russell, Alvis Brazma

“…The reliability of our predictions is confirmed by literature-derived annotations in FlyBase, by overrepresentation of Gene Ontology biological process annotations, and, in a selected set, by detailed gene-specific studies from the literature. …”
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A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization. by Daipeng Chen, Xinxin Liu, Haijiang Wang, Roeland M H Merks, David A Baker

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Modelling trial-by-trial changes in the mismatch negativity. by Falk Lieder, Jean Daunizeau, Marta I Garrido, Karl J Friston, Klaas E Stephan

“…However, the algorithmic nature of these computations and the underlying neurobiological implementation remain controversial. …”
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