Multidisciplinary analysis of the prognosis and biological function of NUBPL in gastric cancer by Luqian Liu, Fengyu Zhang, Jiaye Yu, Pingping Dong, Jing Deng, Weiwei Liu, Xinlei Cao, Juanjuan Huang, Xiaoming Lin, Xiangyang Xue

“…Meanwhile, the ESTIMATE algorithm was used for immune infiltration analysis and prediction of immunotherapy response, and the Genomics of Drug Sensitivity in Cancer (GDSC) database was utilized for the drug sensitivity analysis of NUBPL. …”
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A stratified therapeutic model incorporated with studies on regulatory B cells for elderly patients with newly diagnosed multiple myeloma by Wenjiao Tang, Yan Li, Zhongqing Zou, Jian Cui, Fangfang Wang, Yuhuan Zheng, Li Hou, Ling Pan, Bing Xiang, Hong Chang, Li Zhang, Ting Niu

“…Conclusions For the elderly NDMM, the CEMM2021 algorithm in our center might provide a valuable reference for the guidance of therapeutic strategies, with the combination of Bregs resulting in an effective and clinically meaningful prediction in contemporary treatment.…”
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Strategic optimization of engine performance and emissions with bio-hydrogenated diesel and biodiesel: A RVEA-GRNNs framework by Niti Klinkaew, Attasit Wiangkham, Atthaphon Ariyarit, Prasert Aengchuan, Anupap Pumpuang, Sarunporn Sripratum, Atthaphon Maneedaeng, Jiraphon Srisertpol, Ekarong Sukjit

“…The Generalized Regression Neural Networks model demonstrated high accuracy in predicting engine performance and emissions, with coefficient of determination (R2) values exceeding 0.98 and mean absolute percentage errors below 5 %. …”
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Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity by Amy Dashwood, Ntombizodwa Makuyana, Rob van der Kant, Arman Ghodsinia, Alvaro R. Hernandez, Stephanie Lienart, Oliver Burton, James Dooley, Magda Ali, Lubna Kouser, Francisco Naranjo, Matthew G. Holt, Frederic Rousseau, Joost Schymkowitz, Adrian Liston

“…Here we use SolubiS and dTANGO, computational algorithm-based methods, to predict mutations within the IL2 structure to improve protein production yield in muteins with altered cellular selectivity, to generate combined muteins with elevated therapeutic potential. …”
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Heat transfer with magnetic force and slip velocity on non-Newtonian fluid flow through a porous medium by Muhammad Ramzan, Muhammad Shahryar, Shajar Abbas, Muhammad Amir, Shaxnoza Ravshanbekovna Saydaxmetova, Rashid Jan, Afnan Al Agha, Hakim AL Garalleh

“…This model advances previous studies by demonstrating that fractional derivatives significantly enhance the prediction of fluid behavior in porous media, underscoring the effectiveness of fractional modeling for complex convection processes. …”
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Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progression by Yuhui Tang, Aiqi Xu, Zhongbiao Xu, Jindong Xie, Wei Huang, Liulu Zhang, Yitian Chen, Lu Yang, Shasha Du, Kun Wang

“…Particularly, IL32high Treg imparted an essential effect on tumor evasion and predicted a worsened prognosis of TNBC patients. Furthermore, MCI model enabled to notify the inferior prognosis and immunotherapy resistance in TNBC. …”
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Preliminary evaluation of ShallowHRD performance compared to HRDetect in familial breast cancer tumors by Louise Adel Jensen, Caroline Hey Baekgaard, Mie Bohnensack Larsen, Susanne Eriksen Boonen, Anne Marie Bak Jylling, Zainab Hikmat, Qin Hao, Thomas van Overeem Hansen, Inge Søkilde Pedersen, Martin Jakob Larsen, Mads Thomassen

“…Abstract Determining the Homologous Recombination Deficiency (HRD)-status of a malignant tumor is central in predicting patient response to specific treatments. …”
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Serum Lipid Biomarkers for the Diagnosis and Monitoring of Neuromyelitis Optica Spectrum Disorder: Towards Improved Clinical Management by Li R, Wang J, Wang J, Xie W, Song P, Zhang J, Xu Y, Tian D, Wu L, Wang C

“…Subsequently, we validated the candidate biomarkers in the retrospective cohort and developed diagnostic models using a random forest algorithm. The association between these lipid biomarkers and disease activity was further evaluated in longitudinal analysis.Results: Our analysis identified a panel of serum lipid-related biomarkers that demonstrated significant differences between NMOSD patients and controls. …”
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Experimental Study on Compressive Capacity Behavior of Helical Anchors in Aeolian Sand and Optimization of Design Methods by Qingsheng Chen, Wei Liu, Linhe Li, Yijin Wu, Yi Zhang, Songzhao Qu, Yue Zhang, Fei Liu, Yonghua Guo

“…The compressive capacity of helical anchors constitutes a pivotal performance parameter in geotechnical design. To precisely predict the compressive bearing behavior of helical anchors in aeolian sand, this study integrates in situ testing with finite element numerical analysis to systematically elucidate the non-linear evolution of its load-bearing mechanisms. …”
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Immunotyping of thyroid cancer for clinical outcomes and implications by Jin Xu, Zhen Luo, Dayong Xu, Mujing Ke, Cheng Tan

“…Furthermore, the prognostic model’s utility in predicting immunotherapy response was analyzed. The potential therapeutic drugs were obtained. …”
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Simplification of the diagnostic approach and treatment of Hepatitis C Virus. by Clara C. Sanchez-Rodriguez, Ana M. Mendoza-Martínez, Héctor R. Sánchez-Nuncio, Jorge H. Luna-Domínguez

“…Fibrosis was calculated using the APRI algorithm, finding 53/130 with >1.5 and 60/130 with >3.25, which predicted F3-4. …”
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Potential Metabolic Markers in the Tongue Coating of Chronic Gastritis Patients for Distinguishing Between Cold Dampness Pattern and Damp Heat Pattern in Traditional Chinese Medici... by Yuan S, Zhang R, Zhu Z, Zhou X, Zhang H, Li X, Hao Y

“…The model quality was evaluated by 7-fold cross-validation, and the model validity was evaluated based on R²Y (interpretability of categorical variable Y) and Q² (predictability of the model), and the permutation test was used for further verification. …”
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Novel computational One-Health analysis of fibrinogen-binding protein A in Streptococcus agalactiae Isolated from fish and human cases by Rifaldi Iqbal Yadiansyah, Endang Linirin Widiastuti, Wawan Abdullah Setiawan, Favorisen Rosyking Lumbanraja, Rifky Rizkiantino

“…Three-dimensional structures were predicted through ColabFold and validated using Ramachandran plots. …”
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CcpA-mediated regulation of cellular energy metabolism in the ruminal bacterium Streptococcus bovis by Yunan Weng, Yaqian Jin, Wenze Zhang, Lihong Wang, Hongrong Wang

“…Based on the random forest algorithm, glutamine and UDP-GlcNac were identified as biomarkers under varying glucose conditions and in the presence or absence of ccpA. …”
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Comparing and Combining Artificial Intelligence and Spectral/Statistical Approaches for Elevating Prostate Cancer Assessment in a Biparametric MRI: A Pilot Study by Rulon Mayer, Yuan Yuan, Jayaram Udupa, Baris Turkbey, Peter Choyke, Dong Han, Haibo Lin, Charles B. Simone

“…Combining Z-SSMNet with spectral/statistical approaches significantly enhanced tumor grade prediction, possibly providing an alternative to current prostate tumor assessment.…”
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Klasifikasi Kinerja Akademik Siswa Menggunakan Neighbor Weighted K-Nearest Neighbor dengan Seleksi Fitur Information Gain by Rizky Adinda Azizah, Fitra Bachtiar, Sigit Adinugroho

“…Neighbor Weighted K-Nearest Neighbor algorithm with Information Gain method will be applied to this study to help predict student performance. …”
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Biomarkers of microvascularture by ultra Micro-angiography (UMA) assist to identify papillary thyroid carcinoma (PTC) with atypia of undetermined significance by Qingsong Wang, Zhewei Li, Jie Zhang, Sijie Zhang, Lijun Wang, Hongjian Yao, Hong Zhang, Jing Li, Shuo Wang, Jinglai Sun, Wenhui Zhang, Hui Yu

“…Conclusions This study demonstrated the potential value of microvasculature in the prediction of PTC in AUS Cases and improved the performance of ultrasound examination. …”
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Development of policy research-evidence organizer and public health-policy evaluation tool (prophet): a computing paradigm for promoting evidence-informed policymaking in Nigeria by Kingsley Otubo Igboji, Chigozie Jesse Uneke, Fergus U. Onu, Onyedikachi Chukwu

“…It strategically evaluates and assess level of evidence content, and predict implementation prospects of health policy documents.…”
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Loneliness, insomnia symptoms, social jetlag, and vitamin D deficiency in relation to mental health problems in Japanese female university students: a cross-sectional study by Nodoka Yamashita, Shioka Ishii, Yoriko Kotoku, Takuya Shuo, Hiromi Eto, Hideaki Kondo

“…Loneliness was assessed using the Three-Item Loneliness Scale. Factors predicting mental health problems with a K6 score ≥ 5 were explored using the Mann–Whitney U test, Fisher’s exact probability test, and classification and regression tree (CART) analysis. …”
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Clinical portrait of an "ordinary" patient with benign prostatic hyperplasia and the efficacy of treating lower urinary tract symptoms by V. L. Medvedev, M. E. Efremov, P. V. Shornikov, D. S. Isayeva

“…Indicators of IPSS, Q max and PVR after 3 months of therapy allow predicting the effectiveness of therapy, or suspect the need for surgical treatment.…”
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