Efficacy of alpelisib with rational use of metformin in HR+/HER2- advanced breast cancer patients with <i>PIK3CA</i> mutations (m): retrospective analysis in routine practice of se... by D. A. Filonenko, R. V. Orlova, M. I. Gluzman, A. A. Vakhitova, A. Yu. Goryainova, K. S. Grechukhina, I. I. Bykonya, L. G. Zhukova

“…Pts were stratified to risk groups of HG based on the algorithm before starting ALP and received MET for prevention of HG. …”
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Are Electromyography Data a Fingerprint for Patients with Cerebral Palsy (CP)? by Mehrdad Davoudi, Firooz Salami, Robert Reisig, Dimitrios A. Patikas, Nicholas A. Beckmann, Katharina S. Gather, Sebastian I. Wolf

“…Regarding EMG, a significant reduction was only observed in the ND of the rectus femoris (<i>p</i>-value < 0.001) and soleus (<i>p</i>-value = 0.006). …”
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Risk-based Approach in Obtaining and Analysing the Characteristics of Baikal Skullcap Suspension Cultures by A. A. Shmarova, N. S. Pivovarova, O. N. Abrosimova

“…The plant's value becomes the cause of overexploitation of the skullcap subterranean parts, which leads to the reduction of the population distribution range and inappropriate conditions of collection and harvesting. …”
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THE USE OF INTERACTIVE STUDYING METHODS IN TEACHING OPERATIVE SURGERY AND TOPOGRAPHIC ANATOMY by V.M. Fedorak

“…However, they are guided by the instruction, which consists of algorithm of performing certain surgical techniques or operations. …”
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Towards quantitative assessment of cerebrovascular autoregulation in human neonates using ultrafast ultrasound imaging by Nikan Fakhari, Julien Aguet, Alison Howell, Minh Nguyen, Luc Mertens, Lynn Crawford, Maelys Venet, Christoph Haller, David Barron, John G. Sled, Jérôme Baranger, Olivier Villemain

“…This study aims to use UPD combined with an algorithm for the discrimination of arteries and veins to monitor CAR during DH-CPB in neonates. …”
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Determining optimal strategies for primary prevention of cardiovascular disease: a synopsis of an evidence synthesis study by Olalekan A Uthman, Lena Al-Khudairy, Chidozie Nduka, Rachel Court, Jodie Enderby, Seun Anjorin, Hema Mistry, G J Melendez-Torres, Sian Taylor-Phillips, Aileen Clarke

“…A machine learning study developed a parallel Convolutional Neural Network algorithm with 96.4% recall and 99.1% precision for study screening. …”
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Spatial analysis of air pollutant exposure and its association with metabolic diseases using machine learning by Jingjing Liu, Chang Liu, Zhangdaihong Liu, Yibin Zhou, Xiaoguang Li, Yang Yang

“…By adjusting for demographic and lifestyle confounders, APs effectively predicted the risk of developing MDs (AUROC=0.890, 0.877, 0.710 for diabetes, dyslipidemia, and hypertension, respectively). …”
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Aβ status assessment in a hypothetical scenario prior to treatment with disease‐modifying therapies: Evidence from 10‐year real‐world experience at university memory clinics by Matthias Brendel, Tandis Parvizi, Johannes Gnörich, Christof Elias Topfstedt, Katharina Buerger, Daniel Janowitz, Boris‐Stephan Rauchmann, Robert Perneczky, Carolin Kurz, Dirk Mehrens, Wolfgang G. Kunz, Julia Kusche‐Palenga, Agnes Bernadette Kling, Antonia Buchal, Elizabet Nestorova, Sara Silvaieh, Raphael Wurm, Tatjana Traub‐Weidinger, Sigrid Klotz, Günther Regelsberger, Axel Rominger, Alexander Drzezga, Johannes Levin, Elisabeth Stögmann, Nicolai Franzmeier, Günter U. Höglinger

“…RESULTS In both cohorts, a CSF Aβ42/40 ratio ≥ 7.1% was associated with a low risk of a positive Aβ PET scan (negative predictive value: 94.3%). Implementing two cutoffs revealed 14% to 16% of patients with intermediate results (CSF Aβ42/40 ratio: 5.5%–7.1%), which had a strong benefit from Aβ PET imaging (44%–52% Aβ PET positivity). …”
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A Vision-Based End-to-End Reinforcement Learning Framework for Drone Target Tracking by Xun Zhao, Xinjian Huang, Jianheng Cheng, Zhendong Xia, Zhiheng Tu

“…Across various target trajectories, the VTD3 algorithm demonstrates a significant reduction in average tracking errors along the X-axis and Y-axis of up to <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>34.35</mn><mo>%</mo></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>45.36</mn><mo>%</mo></mrow></semantics></math></inline-formula>, respectively. …”
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Prognostic value of EMT-related genes and immune cell infiltration in thyroid carcinoma by Shuping Wu, Shuping Wu, Yu Liu, Yu Zeng, Xianhui Ruan, Mei Tao, Wenrong Lin, Chang Liu, Hongbin Chen, Hui Liu, Yu Wu

“…Finally, based on the findings from the Weighted Gene Co-Expression Network Analysis (WGCNA) algorithm, LASSO regression analysis, and Kaplan−Meier plotter, we selected five genes (CTSK, C3ORF80, FBLN2, PRELP and SRPX2) associated with patient prognosis. …”
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Development and evaluation of a sensor enabled smart herbicide applicator for inter row crops by Pankaj Malkani, Indra Mani, Pramod Kumar Sahoo, Roaf Ahmad Parray, Sidhartha Sekhar Swain, Asha K．R．, Dharmender, Manojit Chowdhury, Sunil Kumar Rathod, Wahidah H․ Al-Qahtani, Ali Salem, Ahmed Elbeltagi, Abdallah Elshawadfy Elwakeel

“…The microcontroller regulates herbicide flow by controlling the flow control valve with a servo motor, following an algorithm based on green area percentage. Field tests demonstrated a 40 % reduction in herbicide use, 91.26 % weeding efficiency, and 63.4 % field efficiency. …”
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Association of white matter hyperintensity burden and infarct volume in the anterior choroidal artery territory with early neurological progression: a dual-center retrospective stu... by Weiwei Gao, Weiwei Gao, Lixue Wang, Junyi Huang, Yitao Yu, Jingjing She, Jingjing She, Jingjing She, Mingyang Wang, Lijuan Cai, Lijuan Cai, Taishan Kang, Xingyu Chen, Xingyu Chen, Jianzhong Lin, Renjing Zhu, Renjing Zhu, Renjing Zhu

“…WMH burden and infarct volume were assessed using the Fazekas visual rating scale and an automated volumetric quantification method based on lesion prediction algorithm, respectively. The primary outcome was early neurological progression. …”
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Epidemiological, molecular, and evolutionary characteristics of G1P[8] rotavirus in China on the eve of RotaTeq application by Rui Peng, Rui Peng, Mengxuan Wang, Saleha Shahar, Guangping Xiong, Qing Zhang, Lili Pang, Hong Wang, Xiangyu Kong, Dandi Li, Zhaojun Duan

“…Neutralizing epitope, amino acid selection pressure, and evolution dynamics analyses on VP7 and VP4 were performed using BioEdit v.7.0.9.0 and PyMOL v.2.5.2, four algorithms (MEME, SLAC, FEL, and FUBAR) in the Datamonkey online software, and the MCMC model in BEAST v. 1.10.4, respectively. …”
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Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms by Jing Mao, Jianping Lan, Zheyu Zhuang, Ying Chen, Ying Chen, Yushan Ou, Xinhong Su, Xueting Zeng, Fuchen Huang, Zequn Tong, Xiaoqing Lv, Xiaoqing Lv, Xiaoqing Lv, Hui Ke, Zhenlan Wu, Ying Zou, Bo Cheng, Bo Cheng, Bo Cheng, Chao Ji, Chao Ji, Chao Ji, Ting Gong

“…Finally, experimental validation was conducted through real-time quantitative PCR, transmission electron microscopy, and drug prediction.ResultsOur results identified 1,840 DEGs in pemphigus patients compared to controls, with significant enrichment in pathways such as PI3K-Akt signaling and fatty acid metabolism. …”
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Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE) Study by Bernard A Fox, Chichung Wang, Kristin Roman, Carla Coltharp, Carmen Ballesteros-Merino, Shawn M Jensen, Janis M Taube, David L Rimm, Cliff Hoyt, Mei Jiang, Edwin R Parra, Ignacio Wistuba, Elizabeth L Engle, John McGuire, Bethany Remeniuk, Darren Locke

“…Background Emerging data suggest predictive biomarkers based on the spatial arrangement of cells or coexpression patterns in tissue sections will play an important role in precision immuno-oncology. …”
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Optimization study of dynamic emergency feeder bus paths with the sudden interruption of urban railway traffic by Dejie Xu, Huilin Geng, Changwu Hui, Liang Gong, Hang Yuan, Qian Liu

“…Results indicate a 1.7-hour reduction in total passenger travel time and an 84.7% decrease in computation time compared to the Gurobi exact algorithm. …”
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Circulating biomarkers associated with pediatric sickle cell disease by Cecilia Elorm Lekpor, Cecilia Elorm Lekpor, Cecilia Elorm Lekpor, Felix Abekah Botchway, Adel Driss, Alaijah Bashi, Afua D. Abrahams, Kwadwo Asamoah Kusi, Godfred Futagbi, Ernest Alema-Mensah, William Agbozo, Wesley Solomon, Adriana Harbuzariu, Andrew A. Adjei, Jonathan K. Stiles

“…We conclude that a predictive algorithm based on these biomarkers could be developed and validated through longitudinal assessment of within-genotype differences and correlation of the data with disease severity or outcomes. …”
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Uso de inteligencia artificial para predecir complicaciones en cirugías de columna toracolumbar degenerativa: revisión sistemática by G. Ricciardi, J.I. Cirillo Totera, R. Pons Belmonte, L. Romero Valverde, F. López Muñoz, A. Manríquez Díaz

“…Abstract: Objective: We aim to conduct a systematic review of the literature to evaluate the effectiveness of artificial intelligence prediction models in predicting complications in adult patients undergoing surgery for degenerative thoracolumbar pathology compared with other commonly used prediction techniques. …”
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To reveal biomarkers related to macrophage and lactic acid metabolism in renal fibrosis and explore their mechanisms by Chen Yong, Chen Yong, Yongfei Yu, Yongfei Yu, Yuan Wei, Yuan Wei, Guoshun Huang, Guoshun Huang, Lianghui Shu, Lianghui Shu, Kun Gao, Kun Gao, Kun Gao, Enchao Zhou, Enchao Zhou, Enchao Zhou, Enchao Zhou

“…Subsequently, candidate genes were incorporated into machine learning algorithms to identify key feature genes associated with RF. …”
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Demethylase FTO mediates m6A modification of ENST00000619282 to promote apoptosis escape in rheumatoid arthritis and the intervention effect of Xinfeng Capsule by Fanfan Wang, Fanfan Wang, Jianting Wen, Jianting Wen, Jian Liu, Jian Liu, Ling Xin, Yanyan Fang, Yanyan Fang, Yue Sun, Mingyu He, Mingyu He

“…Bioinformatics prediction, MeRIP-qPCR, RIP, and RNA pull-down assays were employed to identify the m6A modification sites of ENST00000619282 and their interactions with FTO/YTHDF1. …”
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