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15341
Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, a...
Published 2025-08-01“…Hub genes were screened using the least absolute shrinkage and selection operator (LASSO) and random forest (RF) algorithms. A cellular model of AMI was established using oxygen- and glucose-deprived AC16 cells. …”
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15342
Characteristics of gut and lung microbiota in patients with lung masses and their relationship with clinical features
Published 2025-08-01“…The diagnostic models were constructed using microbial features identified through two approaches: random forest algorithm with five-fold cross-validation and comparative analysis of significantly differential taxa. …”
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15343
In vitro machine learning-based CAR T immunological synapse quality measurements correlate with patient clinical outcomes.
Published 2022-03-01“…The ML-based automated algorithm quantified CAR-T IS data correlates with the clinical responder and non-responder treated with Kappa-CAR-T cells directly from patients. …”
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15344
Integrative analysis of epigenetic subtypes in acute myeloid Leukemia: A multi-center study combining machine learning for prognostic and therapeutic insights.
Published 2025-01-01“…Drug sensitivity was predicted using the pRRophetic algorithm with GDSC database reference.…”
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15345
Cross-talk of m6A methylation modification and the tumor microenvironment composition in esophageal cancer
Published 2025-07-01“…Single-cell RNA sequencing (scRNA-seq) and a consensus clustering algorithm was employed to classify m6A modification patterns and analyze their relationships with immune cell infiltration and clinical outcomes. …”
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15346
Comprehensive Analysis of the Role of Metabolic Features in Osteoporosis: A Multi-Omics Analysis
Published 2025-05-01“…Finally, three MRGs and one plasma metabolite were selected based on the machine learning algorithm, with AUC of 0.782, 0.714, 0.772 and 0.836, respectively. …”
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15347
Identification of lipid metabolism related immune markers in atherosclerosis through machine learning and experimental analysis
Published 2025-02-01“…Additionally, the ssGSEA algorithm further validated the association of these diagnostic genes with various immune cells. …”
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15348
Machine learning-based radiomics for differentiating lung cancer subtypes in brain metastases using CE-T1WI
Published 2025-06-01“…Among the ten models tested, the LightGBM algorithm exhibited superior performance, with an AUC of 0.853 in the test cohort. …”
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15349
Predictors of community-based health insurance enrollment among reproductive-age women in Ethiopia based on the EDHS 2019 dataset: a study using SHAP analysis technique, 2024
Published 2025-03-01“…Eight machine learning algorithm classifiers were applied to a total weighted sample of 9,013 reproductive-age women and evaluated using performance metrics to predict community-based health insurance enrollment with Python 3.12.2 software, utilizing the Anaconda extension. …”
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15350
Data fusion-based improvements in empirical regression and machine learning for global daily ∼ 8 km resolution sea surface nitrate estimation and interpretation
Published 2025-09-01“…While various global-scale SSN regression and machine learning algorithms based on SSN-environment variable relationships have been developed, the prediction accuracy and spatiotemporal resolution of their applications continue to face limitations. …”
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15351
Control of multi-level quadratic DC-DC boost converter for photovoltaic systems using type-2 fuzzy logic technique-based MPPT approaches
Published 2025-02-01“…By incorporating type-reduction and interval type-2 fuzzy logic principles, the T2FLC enhances robustness, precision, and adaptability to rapidly changing irradiance and temperature levels. …”
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15352
Urban Expansion and Land Use Transformations in Midnapore City (2003–2024): Implications for Sustainable Development
Published 2025-06-01“…These factors led to the reduction of LULC classes possessing substantial ecological value like forests and scrub lands which are becoming more accessible due to the increasing population. …”
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15353
Recovering Pulsar Periodicity from Time-of-arrival Data by Finding the Shortest Vector in a Lattice
Published 2025-01-01“…Identifying such a periodicity from a discrete set of arrival times is a difficult algorithmic problem, In particular when the pulsar is in a binary system. …”
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15354
Single-cell multiomics reveals simvastatin inhibits pan-cancer epithelial-mesenchymal transition via the MEK/ERK pathway in XBP1+ mast cells
Published 2024-11-01“…A prognostic model was established using WGCNA and 12 machine learning algorithms to identify potential mast cell targets. …”
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15355
A prognostic glycolysis-related gene signature in osteosarcoma: implications for metabolic programming, immune microenvironment, and drug response
Published 2025-04-01“…Using the non-negative matrix factorization (NMF) algorithm, patients with OS were stratified into distinct subgroups based on 288 GRGs identified through univariable Cox analysis. …”
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15356
Advancements in Hyperspectral Imaging and Computer-Aided Diagnostic Methods for the Enhanced Detection and Diagnosis of Head and Neck Cancer
Published 2024-10-01“…<b>Results:</b> The meta-analysis findings indicate that LDA surpasses other algorithms, achieving an accuracy of 92%, sensitivity of 91%, and specificity of 93%. …”
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15357
Ethical Foundations of AI-Driven Avatars in the Metaverse for Innovation and User Privacy
Published 2025-01-01“…However, these advances also introduce critical ethical and legal dilemmas surrounding privacy, identity theft, algorithmic bias, and data governance. This study employs a comprehensive multimethodological approach combining systematic literature review, regulatory gap analysis, and ethical framework synthesis. …”
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15358
Exploring the potential of antifungal-loaded proniosomes to consolidate corneal permeation in fungal keratitis: A comprehensive investigation from laboratory characterization to mi...
Published 2025-06-01“…Numerical desirability algorithms selected an optimum TCZ-PNS which boasted plausible %EE (89.51 % ± 0.94 %), nanoscale vesicles consistent with TEM measurements (247.9 ± 0.42 nm), a sufficiently high ZP (−43.42 ± 0.85 mV), and an in-vitro biphasic release profile that remained stable even after Gamma irradiation and short-term storage. …”
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15359
Trading off Iodine and Radiation Dose in Coronary Computed Tomography
Published 2025-05-01“…This review explores the balance between radiation and CM volumes, emphasizing patient-specific protocol optimization to improve diagnostic accuracy while minimizing risks. Radiation dose reduction strategies, such as low tube voltage protocols, prospective ECG-gating, and modern reconstruction algorithms, have significantly decreased radiation exposure, with some studies achieving sub-millisievert doses. …”
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15360
Integrated phenotypic and transcriptomic characterization of desmin-related cardiomyopathy in hiPSC-derived cardiomyocytes and machine learning-based classification of disease feat...
Published 2025-09-01“…Using advanced technologies, including transcriptomics and phenotypic machine learning algorithms, we analyzed how this mutation disrupts cellular function and contributes to disease phenotypes. …”
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