Structure-guided design of partial agonists at an opioid receptor by Balazs R. Varga, Sarah M. Bernhard, Amal El Daibani, Saheem A. Zaidi, Jordy H. Lam, Jhoan Aguilar, Kevin Appourchaux, Antonina L. Nazarova, Alexa Kouvelis, Ryosuke Shinouchi, Haylee R. Hammond, Shainnel O. Eans, Violetta Weinreb, Elyssa B. Margolis, Jonathan F. Fay, Xi-Ping Huang, Amynah Pradhan, Vsevolod Katritch, Jay P. McLaughlin, Susruta Majumdar, Tao Che

“…Here we show that C6-Quino, a bitopic ligand developed through structure-based design, acts as a selective δOR partial agonist. …”
Get full text

An Optimized Position Control via Reinforcement-Learning-Based Hybrid Structure Strategy by Nebiyeleul Daniel Amare, Sun Jick Yang, Young Ik Son

“…Most control system implementations rely on single structures optimized for specific performance criteria through rigorous derivation. …”
Get full text

Visualization of structural and textural changes in the newly formed snow layer during prolonged snowfall by M. P. Tentyukov

“…It is assumed that the structural and textural post-sedimentation transformations of solid precipitation in the upper part of the snow thickness are more controlled by the depth of penetration of the air temperature gradient. …”
Get full text

On the relation between promoter divergence and gene expression evolution by Itay Tirosh, Adina Weinberger, Dana Bezalel, Mark Kaganovich, Naama Barkai

“…The remaining unexplained differences are correlated with the increased divergence of the sequences that flank the binding sites and an apparent modulation of chromatin structure. Our analysis emphasizes the flexibility of promoter structure, and highlights the interplay between specific binding sites and general chromatin structure in the control of gene expression.…”
Get full text

Epitaxial Growth of BaBiO₃ Thin Films on SrTiO₃(001) and MgO(001) Substrates Using Molecular Beam Epitaxy: Controlling the Competition Between Crystal Orienta... by Islam Ahmed, Stefan De Gendt, Clement Merckling

“…In order to grow a variety of structures, a versatile deposition tool such as molecular beam epitaxy must be employed. …”
Get full text

Enhanced Force Systems for Efficient Maxillary Anterior Diastema Closure Using Clear Aligners: Evaluation of Attachments and Enhanced Structural Modifications by Min-Jeong Jee, Yong-Il Kim, Sung-Hun Kim, Seong-Sik Kim, Soo-Byung Park, Youn-Kyung Choi

“…The combination of both modifications provided the most controlled and efficient tooth movement. These results suggest that modifying clear aligners with localized structural enhancements can improve treatment predictability and efficiency. …”
Get full text

DEEP STRUCTURE, TECTONIC EVOLUTION AND HYDROCARBON POTENTIAL OF THE KALAMIT SWELL (NORTHWESTERN SHELF OF THE BLACK SEA) ACCORDING TO DENSITY MODELING DATA by M.V. Kozlenko, Yu.V. Kozlenko

“…The deep structure, tectonic evolution and hydrocarbon potential of the Kalamitsky swell (КS) were determined using the density modeling method. …”
Get full text

Providing a customer satisfaction model of non-attendance services in the social security organization by Hossein Barzgar, Vahid Sanavi Garoosiyan, ali hossein zadeh

“…The variable of customer satisfaction with non-attendance services includes 4 dimensions of infrastructures, culture building, reforming structures, and creativity and innovation. The reliability of the research was checked and confirmed by Cronbach's alpha criterion in SPSS software. …”
Get full text

Health coaching for people with long-term conditions and multimorbidity: a mixed methods prospective service evaluation of Structured Agenda-free Coaching Conversations (StACC) in... by Kate Henry, Austen El-Osta, Kathleen Leedham-Green

“…Abstract Background Enhanced patient engagement has been linked to health service sustainability. The Structured Agenda-free Coaching Conversation (StACC) model aims to support people with one or more long-term conditions through a strengths-based approach: emphasising patient ownership and engagement rather than specific health-related knowledge, skills or lifestyle-related goals. …”
Get full text

A Comprehensive Approach to Synthetic Distribution Grid Generation: Erdős–Rényi to Barabási-Albert by Mohammad Shahraeini

“…To address these limitations and push the research forward, the new algorithm utilizes the Barabási-Albert model to provide more control over the structural features of the generated graphs through the introduction of a novel tuning parameter known as the “richness index”. …”
Get full text

Organizações partidárias e seleção de candidatos no estado de São Paulo by Maria do Socorro Sousa Braga

“…In order to do that, two internal party processes will be examined: the setting and maintaining of the party's organizational structure and the candidate selection for the Camara dos Deputados in the state of Sao Paulo for the PFL, PP, PMDB, PSDB and PT parties. …”
Get full text

Marital power play in patriarchal society, a qualitative study of Ghanaian religious wives' perspectives by Simon Kyei, Bright Agorkpa, Beatrice Benewaa, Nora Shamira Narveh Sadique

“…This study was designed under the phenomenological structure within the qualitative approach framework to examine how women scramble for power in marriage. …”
Get full text

Harnessing Switchgrass for Sustainable Energy: Bioethanol Production Processes and Pretreatment Technologies by Hilal Unyay, Nuriye Altınay Perendeci, Piotr Piersa, Szymon Szufa, Agata Skwarczynska-Wojsa

“…Physical, chemical, and biological pretreatment processes are applied to enhance the breakdown of switchgrass’s lignocellulosic structure. Effects of pretreatments, enzymatic hydrolysis, and fermentation on ethanol yield are discussed in detail. …”
Get full text

Surgical Treatment Results of Osteoporotic Bimalleolar Ankle Fractures in the Elderly by Nadir Özkayın, Kemal Aktuğlu

“…However the insufficiency of the bone structure makes it hard to obtain this purpose. Possible complications enforce having more control on surgical rehabilitation. …”
Get full text

Fully Developed Open Channel Flow Over Clusters of Freshwater Mussels Partially Buried in a Gravel Bed by T. Lazzarin, G. Constantinescu, H. Wu, D. P. Viero

“…The density of the mussels forming the array varies from 26 to 500 mussels/m2. The flow structure is analyzed at large distances from the leading edge of the mussel bed, where the flow can be considered fully developed. …”
Get full text

Electro-Active continuous flax fiber-reinforced epoxy shape memory biocomposites with enhanced mechanical strength for self-shaping multifunctional architectural applications by Asmaa Hassan, Yağmur Bulut, Seyedehgelareh Sanei, Hanaa Dahy

“…Electro-active shape memory composites have recently gained interest for their ability to return to predefined shapes through Joule heating, offering more controllable alternatives to conventional thermal activation. …”
Get full text

Flow Boiling Heat Transfer Enhancement via Femtosecond Laser-Textured Inclined Microfeatures by Frederik Mertens, Thomas Ponnet, Balasubramanian Nagarajan, Senthil Kumar Parimalanathan, Johan Steelant, Sylvie Castagne, Maria Rosaria Vetrano

“…Among the tested surfaces, submicron-scale LIPSSs contribute to the rewetting of the surface but only show a slight improvement when not combined with bigger microscale structures. The inclined grooves result in the most gradual onset, showing almost no incipient overshoot. …”
Get full text

PROPERTIES OF MICELLAR CASEIN AND APPLICATION IN FOOD INDUSTRY by N. A. Dzhangiryan, V. I. Shipulin.

“…Milk casein has important properties that ensure the widespread use of this protein in industry and increased interest in its study by researchers. Studies of the structure of casein in its native state have revealed its micellar structure. …”
Get full text

Active Vibration Control of Plate Partly Treated with ACLD Using Hybrid Control by Dongdong Zhang, Ling Zheng

“…Therefore, its application in structural engineering can be highly appreciated.…”
Get full text

The effect of technology stress on knowledge concealment with the mediating role of job fatigue and moderating work autonomy by Hossein Jamali, Mehdi Kabirinaeini, Zeynab Elahi

“…These programs can include creating flexible work structures that allow employees to choose how to perform their tasks according to their work style and personal abilities. …”
Get full text