A Stability-Indicating HPLC-DAD Method for Determination of Ferulic Acid into Microparticles: Development, Validation, Forced Degradation, and Encapsulation Efficiency by Jessica Mendes Nadal, Maria da Graça Toledo, Yasmine Mendes Pupo, Josiane Padilha de Paula, Paulo Vitor Farago, Sandra Maria Warumby Zanin

“…Chromatographic conditions consisted of a RP C18 column (250 mm × 4.60 mm, 5 μm, 110 Å) using a mixture of methanol and water pH 3.0 (48 : 52 v/v) as mobile phase at a flow rate of 1.0 mL/min with UV detection at 320 nm. The developed method was validated as per ICH guidelines with respect to specificity, linearity, limit of quantification, limit of detection, accuracy, precision, and robustness provided suitable results regarding all parameters investigated. …”
Get full text

The development of a body weight prediction method for Ongole Crossbred cattle using a meta-analysis and field experiment approach by Frediansyah Firdaus, Bayu Andri Atmoko, Panjono ., Yudi Adinata, Tanda Sahat Panjaitan, Noor Hudhia Krishna, Retno Widiyawati, Malik Makmur, Fajar Ariadi

Get full text

Development of a Heuristic Machine Analogy Method for Model Simplification With an Application to a Large‐Scale Model of Gi/Gs Signaling by Liang Yang, David Finlay, Michelle Glass, Stephen Duffull

“…A novel heuristic machine analogy method of model simplification was developed and applied to a motivating example of a model for cAMP signaling switch induced by Gi/Gs pathway competition for the CB1 receptor (consisting of 31 species and 76 parameters) to enable its use in estimation. …”
Get full text

Adapting High-Resolution Respirometry to Glucose-Limited Steady State Mycelium of the Filamentous Fungus Penicillium ochrochloron: Method Development and Standardisation. by Christoph W Schinagl, Pamela Vrabl, Wolfgang Burgstaller

Get full text

A bioanalytical method development and validation for quantification of glycopyrrolate and neostigmine in rat plasma by LC-MS and its application to pharmacokinetic study by P. Vasu Babu, D. Akiladevi

“…Using the LC/MS approach, this work develops a bioanalytical method for quantifying both drugs in rat plasma and applies it to pharmacokinetic studies. …”
Get full text

The results of the development of a personalized method of mandibular foramen searching in the aspect of mproving the efficiency and safety of inferior alveolar nerve block

“…The ideas of different anatomic schools about the positions of mandibular foramen are based on their own research of native, clinical, radiological materials and on the averaged common tendencies. Aim. It was the development, anatomical and clinical evaluation of the effectiveness of the individual method of finding the projection of the mandibular foramen on the ramus of mandible.Materials and methods. …”
Get full text

METHOD OF LIFECYCLE MODELS OF A CORPORATE INFORMATION SYSTEMS SELECTION BASED ON QUANTITATIVE ESTIMATION OF REQUIREMENTS TO SYSTEMS CHARACTERISTICS AND DEVELOPMENT PROCESSES by Maxim I. Petrenko

Subjects: Get full text

Development of a rapid on-site detection method for largemouth bass virus based on RPA-CRISPR/Cas12a system by Na Li, Chunmei Dai, Yuelin Mao, Yimeng Zhang, Huiyuan Yan, Huijiao Wang, Yinghui Qin, Baicheng Huang, Xinjie Wang, Lunguang Yao

“…Rapid, simple, and reliable detection methods are essential for the timely identification of LMBV infections, enabling effective prevention and control measures.MethodsIn this study, a detection platform utilizing the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 12a (Cas12a) system was developed for LMBV. …”
Get full text

Development and Validation of Inductively Coupled Plasma Mass Spectrometry Method for Quantification of Lithium in Whole Blood from Forensic Postmortem Cases by Cherrie Cheuk Yiu Chang, Sys Stybe Johansen, Brian Schou Rasmussen, Kristian Linnet, Ragnar Thomsen

“…In this study, an inductively coupled plasma mass spectrometry (ICP-MS) method was developed and validated for the quantification of lithium in postmortem whole blood. …”
Get full text

Dynamic Effect of Renewable and Non-Renewable Energy Consumption on Ecological Footprint in Selected Developing Countries (Generalized Method of Moments Approach) by Azam Esfahani, Sara Ghobadi, Karim Azarbaiejani

“…To analyze the dynamic effects of energy consumption on the ecological footprint, the Generalized Dynamic Method of Moments (GMM) panel method has been applied. …”
Get full text

Developing a confidence interval-based fuzzy testing method using the small bias estimator of the six sigma quality index by Kuen-Suan Chen, Kuei-Kuei Lai, Chun-Min Yu, Yu-Jin Hsu

Get full text

Substantiation and development of an optimal method of minimally invasive posterior interbody stabilization of vertebrae using distraction cages in patients with lumbar spondylolisthesis by Artem V. Stognii, Volodymyr O. Piatykop, Iurii O. Babalian

“… Objective to improve the effectiveness of treatment of patients with lumbar spondylolisthesis, the authors substantiated and developed a novel method of minimally invasive posterior interbody vertebral stabilization (MIPIVS) using distraction cages. …”
Get full text

Efficient intelligent fault diagnosis method and graphical user interface development based on fusion of convolutional networks and vision transformers characteristics by Chaoquan Mo, Ke Huang, Houxin Ji, Wenhan Li, Kaibo Xu

“…Finally, a graphical user interface (GUI)-based mechanical equipment fault detection system was developed using this method, which holds positive implications for advancing the practical application of intelligent fault diagnosis in mechanical equipment.…”
Get full text

Development and validation of a LC-MS/MS method for the simultaneous determination of simnotrelvir and ritonavir in human serum and bronchoalveolar lavage fluid by Xiaoyu Yang, Wanling Lin, Yushang Zhao, Chaoyue Zhao, Fei Zhou, Dong Wang, Zhihong Yue, Lin Pei, Mei Jia, Bin Cao, Lin-Lin Cao, Hui Wang

“…In this study, we developed a liquid chromatography tandem mass spectrophotometry (LC-MS/MS) method for the simultaneous determination of simnotrelvir, ritonavir and urea concentrations in human serum and BALF samples. …”
Get full text

Development of a numerical method for solving optimization problems approximation of the function given approximately and its derivatives based on the variational approach by Igor Naats, Victoria Igorevna Naats, Elena Yartseva

“…The problem of "recovery" of the function from approximate data is formulated, the basic concepts, definitions and approaches to its solution are briefly described. A numerical method for solving optimization problems of function approximation from approximate data is developed. …”
Get full text

Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer by Norihiro Maeda, Hiromi Nishiyori, Mari Nakamura, Chika Kawazu, Mitsuyoshi Murata, Hiromi Sano, Kengo Hayashida, Shiro Fukuda, Michihira Tagami, Akira Hasegawa, Kayoko Murakami, Kate Schroder, Katharine Irvine, David A. Hume, Yoshihide Hayashizaki, Piero Carninci, Harukazu Suzuki

Get full text

Development of a LC-MS/MS Method for the Simultaneous Detection of Tricarboxylic Acid Cycle Intermediates in a Range of Biological Matrices by Omar Al Kadhi, Antonietta Melchini, Richard Mithen, Shikha Saha

“…It is now well-established that perturbations in the tricarboxylic acid (TCA) cycle play an important role in the metabolic transformation occurring in cancer including that of the prostate. A method for simultaneous qualitative and quantitative analysis of TCA cycle intermediates in body fluids, tissues, and cultured cell lines of human origin was developed using a common C18 reversed-phase column by LC-MS/MS technique. …”
Get full text

PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) by Олег Иванович Бондарев, Мария Сергеевна Бугаева, Евгения Викторовна Уланова

Get full text

Using artificial neural networks to predict indoor particulate matter and TVOC concentration in an office building: Model selection and method development by Saren Gaowa, Zhen Zhang, Jianchun Nie, Linxiao Li, Han A-ru, Zhili Yu

Get full text

Establishment of a framework based on sustainable development for key incident-causing factors in urban excavation incidents using Delphi method by Keivan Zandieh, Amirhossein Hajibabaei

“…In this article, the factors and risks involved in excavation-related incidents have been identified using the Delphi method. In this method, first in the first round, a group of experienced experts is formed who are fully familiar with the technical issues of excavation and its incidents, and then by identifying the factors and risks in the existing literature, a Delphi method questionnaire is prepared and distributed in the second round. …”
Get full text