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1901
Development of a method for quantitative determination of nitric oxide (NO) in rat tissues based on high-performance liquid chromatography and mass spectrometry
Published 2024-05-01“…The developed bioanalytical HPLC-MS/MS methods fully meets the validation requirements. …”
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1902
The Development and Validation of a Simple HPLC-UV Method for the Determination of Vancomycin Concentration in Human Plasma and Application in Critically Ill Patients
Published 2025-02-01“…The run time was noted to be 10 min. This method was evaluated using different greenness tools, which indicated that the method is environmentally friendly. …”
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1903
Development of the composition and research of the equivalence of suppositories with diclofenac sodium by in vitro method using “Dissolution” test for lipophilic solid dosage forms
Published 2019-04-01“…The aim: Development of the composition and investigation of the equivalence of suppositories with sodium diclofenac by in vitro method on a device with a flow-through cell in accordance with modern requirements of SPhU. …”
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1904
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1905
Development and validation of a stability-indicating HPLC method for the simultaneous determination of anticoccidial drugs in veterinary formulations: greenness and whiteness assessment
Published 2025-02-01“…A new, sensitive, and environmentally friendly HPLC method was developed for determining amprolium (AMP), sulfaquinoxaline (SUL), diaveridine (DIV), and vitamin K3 (VIT K3) in their formulations for the first time. …”
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1906
Development of a method for obtaining a suspension of human corneal endothelial cells and its subsequent transplantation in an ex vivo experiment
Published 2022-12-01“…Purpose. Development of method for obtaining a suspension of native human corneal endothelial cells. …”
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1907
UHPLC/MS-MS Analysis of Six Neonicotinoids in Honey by Modified QuEChERS: Method Development, Validation, and Uncertainty Measurement
Published 2013-01-01“…Rapid and reliable multiresidue analytical methods were developed and validated for the determination of 6 neonicotinoids pesticides (acetamiprid, clothianidin, imidacloprid, nitenpyram, thiacloprid, and thiamethoxam) in honey. …”
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1908
Development of a method for simultaneous analysis of glycosaminoglycan disaccharides and evaluating the quality of chondroitin sulfate and hyaluronic acid in food raw materials
Published 2025-01-01“…We developed a comprehensive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous analysis of 19 glycosaminoglycan disaccharide components. …”
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1909
Green bioanalytical method development and validation for estimation of Imeglimin hydrochloride using human plasma in pure form by LC–MS/MS
Published 2025-06-01“…Abstract Background A bioanalytical method was developed and validated in accordance with US FDA guidelines for estimating Imeglimin hydrochloride levels in human plasma using liquid chromatography with mass spectrometry (LC–MS/MS). …”
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1910
Development and Validation of Method for the Quantitative Determination of Zinc in its Chelate Complexes Using Energy Dispersive X-ray Fluorescence Spectroscopy
Published 2021-11-01“…To synthesize Zn(Met)2 chelate complex, to develop and validate a method for its quantitative analysis using the XRF method.Materials and methods. …”
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1911
Development and Validation of a Rapid RP-HPLC Method for the Determination of Venlafaxine Hydrochloride in Pharmaceutical Dosage forms using Experimental Design
Published 2009-01-01“…The objective of the current study was to develop a simple, accurate, precise and rapid reversed-phase HPLC method and subsequent validation as per ICH guidelines for the determination of venlafaxine hydrochloride in pharmaceutical dosage forms. …”
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1912
Development of a DNA Metabarcoding Method for the Identification of Crustaceans (<i>Malacostraca</i>) and Cephalopods (<i>Coleoidea</i>) in Processed Foods
Published 2025-04-01“…To address this need, we developed and validated a DNA metabarcoding method for the authentication of crustaceans and cephalopods in processed food samples, as both are prone to food fraud, especially in mixed products. …”
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1913
Development of a Dispersive Liquid–Liquid Microextraction Method for Quantification of Volatile Compounds in Wines Using Gas Chromatography–Mass Spectrometry
Published 2025-02-01“…<b>Background/Objectives</b>: This study reports the development of a straightforward, efficient, and cost-effective dispersive liquid–liquid microextraction (DLLME) method for the gas chromatography–mass spectrometry (GC-MS) analysis of volatile compounds present in wine. …”
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1914
Development and validation of a dynamic light scattering-based method for viral quantification: A straightforward protocol for a demanding task.
Published 2025-01-01“…This study aimed to develop a reliable, rapid method for viral particle quantification using Dynamic Light Scattering (DLS) as an alternative to traditional virological techniques. …”
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1915
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1916
HPLC method development/validation and skin diffusion study of caffeine, methyl paraben and butyl paraben as skin-diffusing model drugs.
Published 2021-01-01“…The focus of this research was to develop and validate a suitable HPLC method, which allows simultaneous determination of three proposed skin model penetrants to investigate the percutaneous diffusion behavior of their combination: caffeine, methyl paraben and butyl paraben. …”
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1917
Development of dynamic gas generation system for ultratrace amounts of acetone at parts-per-trillion levels with low temperature permeation method
Published 2025-04-01“…Preparation of known-concentration gases at that level is very important to accurately evaluate and calibrate these sensing devices. We developed an accurate dynamic gas generation system with a permeation method at the ppt level for acetone, a well-known biomarker of diabetes and obese, which consists of an accurately low-temperature controlled tube chamber with a thermostat, mass flow controller, custom-built acetone permeation tube with a low permeability, and nitrogen carrier gas. …”
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1918
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1919
Development of a method for measuring mass concentration of cyanides in soil samples using gas chromatography and tandem mass-selective detection
Published 2020-06-01“…The developed method involves the use of 2,3,4,5,6-pentafluorobenzyl bromide as a derivatizing agent and GC/MS/MS with methane negative ion chemical ionization. …”
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1920