Quinolin-4-ones: Methods of Synthesis and Application in Medicine by Katarzyna Gach-Janczak, Justyna Piekielna-Ciesielska, Jakub Waśkiewicz, Kamil Krakowiak, Karol Wtorek, Anna Janecka

“…The first synthesis of quinolinones took place at the end of the 19th century, and the most recent methods were published just a few years ago. They allow for obtaining an unlimited number of analogs differing in biological properties. …”
Get full text

Assessing computational methods of cis-regulatory module prediction. by Jing Su, Sarah A Teichmann, Thomas A Down

“…We also propose key considerations for the development and evaluation of future CRM-prediction methods.…”
Get full text

Methods for Detection and Mapping of Methylated and Hydroxymethylated Cytosine in DNA by Olga Kisil, Alexander Sergeev, Anna Bacheva, Maria Zvereva

“…The growing importance of 5hmC has prompted the development of a multitude of methods for the qualitative and quantitative analysis of 5hmC in recent years, thereby facilitating researchers’ understanding of the mechanisms underlying the onset and progression of numerous diseases. …”
Get full text

Modern (rational) methods for detecting genetic features of athletes by A. V. Zholinsky, A. I. Kadykova, V. S. Feshchenko, M. G. Hovhannisyan, A. V. Zorenko, R. V. Deev

“…Molecular genetic methods are an integral part of recent medicine. Polymerase chain reaction, Sanger sequencing, next-generation sequencing are widely used in many areas: diagnostics of infectious, inherited, oncological diseases, prenatal screening, study of polymorphisms that increase the risk of developing multifactorial diseases or promoting development physical qualities necessary to achieve success in sports and competitive activity. …”
Get full text

Modern Capacities, Methods, and Means of Forensic Construction Investigations by A. Yu. Butyrin, E. B. Stativa

“…It is shown that a timely replenishment of a construction-expert’s instrumental arsenal with modern methods and techniques of examination based on the latest scientific and technological advances guarantees sustainable development of forensic construction examinations as one of the most demanded areas of expert activity in Russian legal proceedings.…”
Get full text

Analysis of modern types of cyberterrorism and methods of countering them by Kakimzhan Bishmanov, Zarina Muratzhan, Zhanat Dilbarkhanova, Viktoriya Lyutsik

“…Methods such as experimentation, comparison, analysis, and synthesis were employed to achieve this purpose. …”
Get full text

CRITICAL REVIEW OF METHODS FOR EVALUATING ACOUSTIC CHARACTERISTICS OR PREMISES by R. S. Fediuk, A. V. Baranov, R. A. Timokhin

“…Considering the variety of international building standards for acoustic insulation and soundproofing of buildings, it is essential to systematize the modern methods of studying these characteristics. The purpose of the study was a comprehensive review of methods for determining acoustic characteristics in construction, as well as an analysis of literature and international standards to improve the health and comfort of the urban population.Main part: Due to the variety and complication of the study of the acoustic characteristics of buildings, premises and individual walling, the article provides an analysis of methods for evaluating these characteristics. …”
Get full text

Methods for obtaining liposomal systems to be used in the food industry by E. V. Lisovaya, V. V. Lisovoy, E. P. Victorova

“…It should be noted that development of methods for producing liposomal systems that could be implemented on an industrial scale for the intensive introduction of these systems in food technology is now becoming increasingly important.…”
Get full text

Load Forecasting in Electrical Grids: Analysis of Methods and their Trends by Kyryk V.V., Shatalov Y.O.

“…This analysis evaluates various forecasting approaches, including statistical methods, artificial intelligence, fuzzy logic, ensemble methods, and hybrid systems, to understand their evolution and current state. …”
Get full text

PROACTIVE MANAGEMENT AND METHODS OF THE TEAM WORKING EFFICIENCY IMPROVEMENT by Г. І. Ємельянова

“…In the article characteristic of moderation as method of the group approach (group work) in respect of solving problems is given. …”
Get full text

Current Treatment Methods for Charcot–Marie–Tooth Diseases by Hongxian Dong, Boquan Qin, Hui Zhang, Lei Lei, Shizhou Wu

“…These methods have brought new options for CMT reclassification and led to an exciting era of treatment target discovery for this incurable disease. …”
Get full text

Methods for forming skills of solving “rule of three” problems by Lyubov Leonidovna Burkova, Lyana Levovna Bagova

“…As a result, an alternative hypothesis has been confirmed: the quality of training in solving problems of finding the fourth proportional one will increase if creative exercises on compiling and transforming tasks are offered at all stages of work on tasks. Research methods: pedagogical experiment, methods of mathematical statistics (“Sign Criterion”).…”
Get full text

Information Content Methods for Semantic Similarity: An Experimental Assessment by Antonio de Nicola, Anna Formica, Ida Mele, Francesco Taglino

Get full text

Deep Reinforcement Learning: A Chronological Overview and Methods by Juan Terven

“…It aims to serve both as an introduction for newcomers to the field and as a practical guide for those seeking to select the most appropriate methods for specific problem domains. Methods: We begin by outlining fundamental reinforcement learning principles, followed by an exploration of early tabular Q-learning methods. …”
Get full text

Methods and effective algorithms for solving multidimensional integral equations by A. B. Samokhin

“…Recently, due to the development of computer technology and methods of computational mathematics, integral equations have been used for the numerical solution of specific problems. …”
Get full text

Foresight in the diagnosis of trematodiasis: innovations versus routine methods by E. A. Perina, E. S. Khmelevskaya, O. S. Fedorova, V. V. Ivanov

“…Therefore, development of modern and effective non-invasive methods for detection of trematode infections with high sensitivity and specificity, including screening in endemic regions, is relevant.The present review analyzes the results of 90 clinical trials and experimental studies on the diagnosis of trematode infections using the PubMed search engine and the eLibrary database. …”
Get full text

Methods for Domain Specification of Verification-Oriented Process Ontology by Natalia O. Garanina, Igor S. Anureev, Olesya I. Borovikova, Vladimir E. Zyubin

“…In this paper, we present methods for the development of verification-oriented domain-specific process ontologies which are used to describe parallel and distributed systems of subject fields. …”
Get full text

Modern methods of studying of human gastro-intestinal microflora by Ye. A. Poluektova, O. S. Lyashenko, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin

“…To discuss modern concepts on the structure and functions of intestinal microflora and its possible effect on development of certain diseases, as well as the basic methods of diagnostics of disorders of its qualitative and quantitative structure.Key points. …”
Get full text

Ensembling methods for protein-ligand binding affinity prediction by Jiffriya Mohamed Abdul Cader, M. A. Hakim Newton, Julia Rahman, Akmal Jahan Mohamed Abdul Cader, Abdul Sattar

“…Most of the existing deep learning methods for protein-ligand binding affinity prediction utilize single models and suffer from low accuracy and generalization capability. …”
Get full text

Challenges of using tissue engineering methods in the treatment of hypospadias by P. Wilczek, P. Wilczek, D. Bociaga, M. Krakos, M. Krakos, A. Wierzbicka

Get full text