Development and Validation of an HPLC-MS/MS Method for the Simultaneous Quantification of Vitexin and Isovitexin in Rabbit Plasma: Pharmacokinetic Insights on a Microcapsule Formulation by Duc Tuan Nguyen, Trung Nguyen Nguyen Le, Duc Kien Ngo, Hien Minh Khuu, Khang Thien Tran, Hoang Thanh Le, Hung Viet Tran, Truong-Thang Nguyen Phan, Vo Thi Kim Khuyen, Han Hoang Do, Nhu Huynh Mai, Quan Minh Le

“…To overcome this challenge, chitosan-coated alginate microcapsules were prepared for intragastrical administration to rabbits. An LC-MS/MS method was developed and validated for the simultaneous determination of vitexin and isovitexin in the plasma of treated rabbits, using salicylic acid as the internal standard. …”
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Development and validation of an LC-MS/MS method for the simultaneous estimation of tadalafil and macitentan in rat plasma: Greenness assessment and design of experiment approach by Sravanthi Gandu, Kumaraswamy Gandla, Lalitha Repudi

“…This study presents the development and validation of a sensitive LC-MS/MS method for the simultaneous quantification of tadalafil and macitentan in rat plasma, enabling detailed pharmacokinetic profiling following single-dose administration. …”
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Development and Validation of a LC-MS/MS Method for the Determination of Nitrofuran Metabolites in Soft-Shell Turtle Powder Health Food Supplement by EunChae Ryu, Ji Sung Park, Sib Sankar Giri, Se Chang Park

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A novel quality by design approach for developing an HPLC method to analyze herbal extracts: A case study of sugar content analysis. by Jingyuan Shao, Wen Cao, Haibin Qu, Jianyang Pan, Xingchu Gong

“…The aim of this study was to present a novel analytical quality by design (AQbD) approach for developing an HPLC method to analyze herbal extracts. …”
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Developing an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method by Sam Chidi Ibeneme, Eunice Odoh, Nweke Martins, Georgian Chiaka Ibeneme

“…Evidence quality and bias were assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) and the Mixed Method Appraisal Tool (MMAT), respectively. …”
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Development and Validation of the HPLC Method for Quantification of the Innovative Drug DD217, Factor Xa Inhibitor, in Rat Plasma for a Pharmacokinetic Study by N. S. Dubovik, D. F. Guranda, G. V. Ramenskaya, D. G. Tovbin, D. N. Tarasov, A. Yu. Savchenko, V. S. Arnautov

“…The aim of this study was to develop and validate a method for DD217 determination in rat plasma by means of high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) to carry out pharmacokinetic studies.Materials and methods. …”
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Evaluating integrated development environments using the TOPSIS method and Schweizer-Sklar power aggregation operator: implications for university students’ psychological management by Lijun Ma, Fengyu Guo, Zeeshan Ali, Shi Yin

“…Finally, numerical examples are presented to compare the proposed ranking results with existing ones, demonstrating the effectiveness of these methods in optimizing IDE selection and supporting students' psychological well-being.…”
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O-ring-induced transverse aortic constriction (OTAC) is a new simple method to develop cardiac hypertrophy and heart failure in mice by Yasuhisa Nakao, Jun Aono, Mika Hamaguchi, Kayo Takahashi, Tomohisa Sakaue, Katsuji Inoue, Shuntaro Ikeda, Osamu Yamaguchi

“…To optimize and simplify this method, we proposed O-ring-induced transverse aortic constriction (OTAC) in mice. …”
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[225Ac]Ac-PSMA-617 production method: development of an efficient and reproducible radiolabelling process for establish a clinical routine production by Michela Aurilio, Aureliana Esposito, Monica Buonanno, Anna Morisco, Costantina Maisto, Stefania Scala, Secondo Lastoria

“…On this basis, the aim of this study is to develop an [225Ac]Ac-PSMA 617 production method, to assess the efficiency and reliability of the radiosynthesis as a support for establish a clinical routine production for metastatic castration resistant prostate cancer treatment. …”
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Development and Validation of a Segment Fiber Model for Simulating Seismic Collapse in Steel-Reinforced Concrete Structures Using the Discrete Element Method by Qingyu Duan, Qiang Wang, Chunxiao Yang

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The pipB Gene as Target for Development of Detection Method of Pathogenic Bacteria Salmonella typhi Using Real-time Polymerase Chain Reaction by Muktiningsih Nurjayadi, Gusti Angieta Putri, Ananda Indah Putri Sihombing, Puan Aqila Azizah, Anisa Fitriyanti, Royna Rahma Musie, Helzi Angelina, Grace, Agus Setiawan, Dandy Akbar Juliansyah, Jefferson Lynford Declan, Gladys Indira Putri, Siti Fatimah, Adinda Myra Amalia Putri, Vira Saamia, Irma Ratna Kartika, Fera Kurniadewi, Shyi-Tien Chen, Bassam Abomoelak, Hesham A. El Enshasy

“…Based on the results, Salmonella typhi pipB primer successfully detected Salmonella typhi bacteria DNA rapidly, specifically, and sensitively using the real-time polymerase chain reaction method. …”
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Development and application of a core competency evaluation index system for pediatric asthma specialist nurses in China: a mixed-method study by Yi Qin, Xiaoyan Cai, Yelin Ji, Jianing Lu, Caifeng Zhang, Yan Gao, Shujing Yan, Rongshan Chen, Rulin Huang, Lan Ma, Xiao Chun, Fengxia Yan

“…Methods Literature review and semi-structured interviews were performed to developed the initial competencies evaluation index system for pediatric asthma specialist nurses. …”
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Development of a Numerical Prediction Method for the Strain Energy Density of Welded Joints Using Structural Stresses Derived from Nodal Forces by Simone Lucertini, Giulia Morettini, Filippo Cianetti

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Effect of applying six thinking hats teaching method for development through life span course on students opinion and critical thinking skills by Amal Ahmed Elbilgahy, Fadiyah Jadid Alanazi

“…Abstract Background Nursing education plays a critical role in developing students' critical thinking skills. Conventional lecture-based methods struggle to hold the attention of today's students. …”
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HPLC-UV method development and validation for anticancer drug sorafenib and the co-prescribed drug dexamethasone: application to pharmacokinetic evaluation of sorafenib nanoformulations by Abdul Mateen, Abad Khan, Ismail Khan, Saifullah Khan Khalil, Lateef Ahmad, Muhammad Junaid, Saqib Jehan, Muhammad Sohail Anwar, Muhammad Faheem, Abdul Salam

“…A high-performance liquid chromatography (HPLC) method was developed for the simultaneous determination of sorafenib with a commonly co-prescribed drug, dexamethasone, using meloxicam as an internal standard. …”
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Effect of Corona Treatment Method to Carvacrol Nanocoating Process for Carvacrol/Halloysite-Nanotube/Low-Density-Polyethylene Active Packaging Films Development by Aris E. Giannakas, Vassilios K. Karabagias, Amarildo Ndreka, Aikaterini Dimitrakou, Areti A. Leontiou, Katerina Katerinopoulou, Michael A. Karakassides, Charalampos Proestos, Constantinos E. Salmas

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Retraction: Investigating the role of education, foreign investment and economic development for sustainable environment in BRI countries: application of method of movements quantile regression by Frontiers Editorial Office

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Development of a method for determining the structure of mini-grid, taking into account optimal routes of power lines in an area with sharply heterogeneous landscape by V. A. Tkachenko

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Prioritizing image processing and big data analytics factors for software development using DEMATEL-choquet method in bipolar complex fuzzy context by Ruimin Ma

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Evaluation of cannabis product mislabeling: The development of a unified cannabinoid LC-MS/MS method to analyze e-liquids and edible products by Ashleigh E. Outhous, Alaina K. Holt, Justin L. Poklis, Michelle R. Peace

“…A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the separation and quantitation of 21 cannabinoids. …”
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