Smart CAR-T Nanosymbionts: archetypes and proto-models by Juan C. Baena, Juan C. Baena, Juan Sebastián Victoria, Juan Sebastián Victoria, Alejandro Toro-Pedroza, Alejandro Toro-Pedroza, Cristian C. Aragón, Cristian C. Aragón, Joshua Ortiz-Guzman, Joshua Ortiz-Guzman, Joshua Ortiz-Guzman, Juan Esteban Garcia-Robledo, Juan Esteban Garcia-Robledo, David Torres, Lady J. Rios-Serna, Lady J. Rios-Serna, Ludwig Albornoz, Joaquin D. Rosales, Joaquin D. Rosales, Carlos A. Cañas, Carlos A. Cañas, Carlos A. Cañas, Gustavo Adolfo Cruz-Suarez, Gustavo Adolfo Cruz-Suarez, Gustavo Adolfo Cruz-Suarez, Gustavo Adolfo Cruz-Suarez, Felipe Ocampo Osorio, Felipe Ocampo Osorio, Felipe Ocampo Osorio, Tania Fleitas, Ivan Laponogov, Alexandre Loukanov, Alexandre Loukanov, Alexandre Loukanov, Kirill Veselkov, Kirill Veselkov

“…However, despite this promise, translation into clinical settings remains difficult due to regulatory hurdles, scalability issues, and inconsistent reproducibility in human models. At the same time, artificial intelligence (AI), with its powerful algorithms for data analysis and predictive modeling, is transforming how we design, evaluate, and monitor advanced therapies, including the optimization of manufacturing processes. …”
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Development of compact mechanism for lithium-ion battery venting gas fires using Cantera ordinary differential equation neural network algorithm by Mengjie Li, Hao Hu, Li Lu, Huangwei Zhang

“…This integration allows for the optimization of a wide range of chemical reactions, improving both the precision and versatility of reaction mechanism development. …”
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A binary gridding path-planning method for plant-protecting UAVs on irregular fields by Wang-ying XU, Xiao-bing YU, Xin-yu XUE

“…In this study, we proposed a binarization multi-objective model for the irregular field area, specifically an improved non-dominated sorting genetic algorithm–II based on the knee point and plane measurement (KPPM-NSGA-ii). …”
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Research and Optimization of White Blood Cell Classification Methods Based on Deep Learning and Fourier Ptychographic Microscopy by Mingjing Li, Junshuai Wang, Shu Fang, Le Yang, Xinyang Liu, Haijiao Yun, Xiaoli Wang, Qingyu Du, Ziqing Han

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Multi-objective design optimization of a transonic axial fan stage using sparse active subspaces by Richard Amankwa Adjei, Chengwei Fan

“…Active subspace was used to compute the active variables via singular value decomposition and a hybrid polynomial correlated function expansion was used to construct a surrogate model on the active subspace. Coupled with freeform method and multi-objective genetic algorithm, an automated optimization loop was run at a single operating condition. …”
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Optimizing a Dynamic Vehicle Routing Problem with Deep Reinforcement Learning: Analyzing State-Space Components by Anna Konovalenko, Lars Magnus Hvattum

“…<i>Results:</i> Our findings demonstrate that a carefully designed state space in the formulation of the DVRP significantly improves RL performance. Notably, incorporating derived features and selectively applying feature transformation enhanced the model’s decision-making capabilities. …”
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HiGMA-DADCN: Hirudinaria granulosa multitropic algorithm optimised double attention enabled deep convolutional neural network for psoriasis classification by Soumya C S, Jayanna H S

“…This model integrates two key components the HiGMA algorithm and a double attention module designed to enhance segmentation and boost overall classification performance. …”
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Deep Reinforcement Learning-Based Two-Phase Hybrid Optimization for Scheduling Agile Earth Observation Satellites by Guanghui Zhou, Zhicheng Jin, Dongning Liu

“…To balance solution quality and computational efficiency, a deep reinforcement learning (DRL)-based algorithmic framework is proposed. A Markov decision process (MDP) is formulated as the foundational model for the DRL architecture. …”
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Min3GISG: A Synergistic Feature Selection Framework for Industrial Control System Security with the Integrating Genetic Algorithm and Filter Methods by Saiprasad Potharaju, Swapnali N. Tambe, G. Madhukar Rao, M. V. V. Prasad Kantipudi, Kalyan Devappa Bamane, Mininath Bendre

“…This study aims to enhance ICS security by improving attack detection through an optimized feature selection framework that balances dimensionality reduction and classification accuracy. …”
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An Intelligent Crow Search Optimization and Bi-GRU for Forest Fire Detection System Using Internet of Things by Syed Abdul Moeed, Bellam Surendra Babu, M. Sreevani, B. V. Devendra Rao, R. Raja Kumar and Gouse Baig Mohammed

“…CSO is inspired by the intelligent foraging behavior of crows, and when combined with fractional calculus, it provides a robust optimization framework that improves the accuracy and efficiency of the AI model. …”
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A novel method for optimizing epilepsy detection features through multi-domain feature fusion and selection by Guanqing Kong, Guanqing Kong, Shuang Ma, Shuang Ma, Wei Zhao, Wei Zhao, Haifeng Wang, Haifeng Wang, Qingxi Fu, Qingxi Fu, Jiuru Wang

“…To extract features strongly correlated with epileptic classification detection, an improved particle swarm optimization (PSO) algorithm and Pearson correlation analysis are combined. …”
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Optimizing radiomics for prostate cancer diagnosis: feature selection strategies, machine learning classifiers, and MRI sequences by Eugenia Mylona, Dimitrios I. Zaridis, Charalampos Ν. Kalantzopoulos, Nikolaos S. Tachos, Daniele Regge, Nikolaos Papanikolaou, Manolis Tsiknakis, Kostas Marias, ProCAncer-I Consortium, Dimitrios I. Fotiadis

“…Key Points Radiomics is a growing field that can still be optimized. Feature selection method impacts radiomics models’ performance more than ML algorithms. …”
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Optimizing blood glucose predictions in type 1 diabetes patients using a stacking ensemble approach by Vincent B. Liu, Laura Y. Sue, Oscar Madrid Padilla, Yingnian Wu

“…GRU had the best predictive accuracy of the initial models. Grey Wolf optimization contributed to achieving optimal baseline model results. …”
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A Practical Method for Red-Edge Band Reconstruction for Landsat Image by Synergizing Sentinel-2 Data with Machine Learning Regression Algorithms by Yuan Zhang, Zhekui Fan, Wenjia Yan, Chentian Ge, Huasheng Sun

“…With the optimal model, three red-edge bands of Landsat OLI were subsequently obtained in alignment with their derived vegetation indices. …”
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Optimizing Stroke Risk Prediction: A Primary Dataset‐Driven Ensemble Classifier With Explainable Artificial Intelligence by Md. Maruf Hossain, Md. Mahfuz Ahmed, Md. Rakibul Hasan Rakib, Mohammad Osama Zia, Rakib Hasan, Md. Rakibul Islam, Md. Shohidul Islam, Md Shahariar Alam, Md. Khairul Islam

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A Robust Gaze Estimation Approach via Exploring Relevant Electrooculogram Features and Optimal Electrodes Placements by Zheng Zeng, Linkai Tao, Hangyu Zhu, Yunfeng Zhu, Long Meng, Jiahao Fan, Chen Chen, Wei Chen

“…The MAE and RMSE can be improved to 2.80&#x00B0; and 3.74&#x00B0; ultimately, while only using 10 features extracted from 2 channels. …”
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Deep learning algorithm on H&E whole slide images to characterize TP53 alterations frequency and spatial distribution in breast cancer by Chiara Frascarelli, Konstantinos Venetis, Antonio Marra, Eltjona Mane, Mariia Ivanova, Giulia Cursano, Francesca Maria Porta, Alberto Concardi, Arnaud Gerard Michel Ceol, Annarosa Farina, Carmen Criscitiello, Giuseppe Curigliano, Elena Guerini-Rocco, Nicola Fusco

“…DL-based histopathological analysis represents a valuable tool for improving patient management and tailoring treatment approaches based on molecular biomarker status.…”
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Optimized Tile Quality Selection in Multi-User 360&#x00B0; Video Streaming by Moatasim Mahmoud, Stamatia Rizou, Andreas S. Panayides, Nikolaos V. Kantartzis, George K. Karagiannidis, Pavlos I. Lazaridis, Zaharias D. Zaharis

“…In this paper, we propose an optimized multi-user tiled 360&#x00B0; video streaming framework. …”
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Optimized CNN-Bi-LSTM–Based BCI System for Imagined Speech Recognition Using FOA-DWT by Meenakshi Bisla, Radhey Shyam Anand

“…EEG signal is enhanced using firefly optimization algorithm (FOA)–based optimized soft thresholding of high-frequency detail components obtained by DWT decomposition. …”
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Compatible matching and synergy operation optimization of hydrogen-electric hybrid energy storage system in DC microgrid by Banghua Du, Yanyu Peng, Yang Li, Changjun Xie, Shihao Zhu, Wenchao Zhu, Yang Yang, Li You, Leiqi Zhang, Bo Zhao

“…A multi-objective optimization model is then developed to balance efficiency and lifespan, which is solved by the NSGA-III algorithm. …”
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