ADMET evaluation in drug discovery: 21. Application and industrial validation of machine learning algorithms for Caco-2 permeability prediction by Dong Wang, Jieyu Jin, Guqin Shi, Jingxiao Bao, Zheng Wang, Shimeng Li, Peichen Pan, Dan Li, Yu Kang, Tingjun Hou

“…We believe that the model developed in this study could represent a reliable tool for assessing Caco-2 permeability during early-stage drug discovery and the chemical transformation rules derived here could provide insights for optimizing Caco-2 permeability. Scientific contribution A comprehensive validation of various machine learning algorithms combined with diverse molecular representations on a large dataset for predicting Caco-2 permeability was reported. …”
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A novel trajectory learning method for robotic arms based on Gaussian Mixture Model and k-value selection algorithm. by Jingnan Yan, Yue Wu, Kexin Ji, Cheng Cheng, Yili Zheng

“…Experimental results demonstrate that, compared to the traditional Gaussian Mixture Model approach, the proposed method improves trajectory accuracy by more than 15%, as shown by reductions in both the Mean Absolute Error and the Root Mean Square Error. …”
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Robust Optimization for Microgrid Management With Compensator, EV, Storage, Demand Response, and Renewable Integration by Hamid Hematian, Mohamad Tolou Askari, Meysam Amir Ahmadi, Mahmood Sameemoqadam, Majid Babaei Nik

“…To efficiently solve this optimization problem, the C&CG algorithm is utilized. …”
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Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

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Optimizing electric vehicle energy consumption prediction through machine learning and ensemble approaches by Izhar Hussain, Kok Boon Ching, Chessda Uttraphan, Kim Gaik Tay, Adeeb Noor, Sufyan Ali Memon

“…The K-Nearest Neighbors (KNN) algorithm is employed as the base model, with hyperparameter optimization performed using GridSearchCV, RandomizedSearchCV, Optuna, and Particle Swarm Optimization (PSO). …”
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Data enhanced iterative few-sample learning algorithm-based inverse design of 2D programmable chiral metamaterials by Zhao Zeyu, You Jie, Zhang Jun, Du Shiyin, Tao Zilong, Tang Yuhua, Jiang Tian

“…In this way, the DEIFS algorithm replaces the time-consuming iterative optimization process with a faster and simpler approach that achieves accurate inverse design with dataset whose amount is at least one to two orders of magnitude less than most previous deep learning methods, reducing the dependence on simulated spectra. …”
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An Intelligent Optimization System Using Neural Networks and Soft Computing for the FMM Etching Process by Wen-Chin Chen, An-Xuan Ngo, Jun-Fu Zhong

“…Experimental results demonstrate a marked improvement in product yield and process stability while reducing manufacturing costs. …”
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Optimizing prediction of metastasis among colorectal cancer patients using machine learning technology by Raoof Nopour

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Data-Driven Robust Optimization for Solving the Heterogeneous Vehicle Routing Problem with Customer Demand Uncertainty by Jingling Zhang, Mengfan Yu, Qinbing Feng, Longlong Leng, Yanwei Zhao

“…Through test experiments, it is proved that the robust optimization model can effectively reduce the number of customers affected by the uncertainty, greatly improve customer satisfaction, and effectively reduce total cost and demonstrate that the improved algorithm also exhibits good performance.…”
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A Clustering-Guided Integer Brain Storm Optimizer for Feature Selection in High-Dimensional Data by Jia Yun-Tao, Zhang Wan-Qiu, He Chun-Lin

“…Since the number of feature clusters is far smaller than the size of original features, IBSO-C can find an optimal feature subset fast. Compared with several existing algorithms on some real-world datasets, experimental results show that IBSO-C can find feature subset with high classification accuracy at less computation cost.…”
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Multi-Objective Optimization of Machinability and Energy Consumption of Cast Iron Depending on Cooling Rate by Burak Öztürk, Fuat Kara

“…Energy efficiency has become a critical focus in sustainable production techniques and cost-effective machining processes. This variation directly influences machinability, with higher hardness generally improving surface quality. …”
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A Comparative Analysis of Hyper-Parameter Optimization Methods for Predicting Heart Failure Outcomes by Qisthi Alhazmi Hidayaturrohman, Eisuke Hanada

“…The XGBoost models exhibited moderate improvement (+0.01683) post-validation. Bayesian Search had the best computational efficiency, consistently requiring less processing time than the Grid and Random Search methods. …”
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Cognitive FDA-MIMO Radar Network’s Transmit Element Selection Algorithm for Target Tracking in a Complex Interference Scenario by Yingfei Yan, Haihong Tao, Jingjing Guo, Biao Yang

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Modeling and optimization of culture media for recombinant Helicobacter pylori vaccine antigen HpaA by Runqing Tan, Song Zhou, Min Sun, Yu Liu, Xiumei Ni, Jin He, Gang Guo, Kaiyun Liu

“…The H. pylori adhesin protein HpaA has demonstrated strong immunogenicity across various adjuvants and dosage forms, positioning it as a key candidate antigen for recombinant subunit vaccines against H. pylori. Optimizing fermentation culture conditions is an effective strategy to enhance product yield and lower production costs. …”
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An intelligent stochastic optimization approach for air cargo order allocation under carbon emission constraints. by Zhenzhong Zhang, Ling Zhang, Deqiang Fu, Weichun Li

“…The method finds the optimal solution through an improved adaptive large-scale neighborhood search algorithm and uses a scenario generation technique to generate the scenarios required for evaluating candidate solutions to the high-dimensional stochastic optimization problem. …”
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User Experience Optimization Researcb on Personalized Pusb Approacb of IPTV Service Based on Label of Contents by Yingbo Zhu, Jianwei Diao, Bo Kang, Shengqiang Liu

“…It is needed to introduce active personalized push approach of content in order to improve user experience, due to higher cost of remote controller than PC and mobile phone. …”
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Multi‐objective multi‐period optimal site and size of distributed generation along with network reconfiguration by Ghulam Abbas, Zhi Wu, Aamir Ali

“…To address the pointed‐out challenge of multiperiod optimal DG allocation and reconfiguration while simultaneously decreasing the cost of energy supplied, the cost of energy lost, and the voltage deviation, a novel Multi‐objective Bidirectional co‐evolutionary algorithm (BiCo) is implemented. …”
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Reinforcement Learning for Optimizing Renewable Energy Utilization in Buildings: A Review on Applications and Innovations by Panagiotis Michailidis, Iakovos Michailidis, Elias Kosmatopoulos

“…The current review systematically examines RL-based control strategies applied in BEMS frameworks integrating RES technologies between 2015 and 2025, classifying them by algorithmic approach and evaluating the role of multi-agent and hybrid methods in improving real-time adaptability and occupant comfort. …”
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Application of artificial intelligence and red-tailed hawk optimization for boosting biohydrogen production from microalgae by Hegazy Rezk, Ali Alahmer, Abdul Ghani Olabi, Enas Taha Sayed

“…Subsequently, the red-tailed hawk algorithm (RTH) is used to determine the optimal values for the process parameters, corresponding to maximum hydrogen yield. …”
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An Optimal Charging Strategy for PV-Based Battery Swapping Stations in a DC Distribution System by Shengjun Wu, Qingshan Xu, Qun Li, Xiaodong Yuan, Bing Chen

“…Then, a particle swarm optimization (PSO) algorithm is developed to calculate the optimal charging power and to minimize the charging cost for each time slot. …”
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