Gain-of-Function and Loss-of-Function Mutations in the RyR2-Expressing Gene Are Responsible for the CPVT1-Related Arrhythmogenic Activities in the Heart by Roshan Paudel, Mohsin Saleet Jafri, Aman Ullah

“…Four primary mechanisms have been proposed to describe CPVT1 with a RyR2 mutation: (a) gain-of-function, (b) destabilization of binding proteins, (c) store-overload-induced Ca²⁺ release (SOICR), and (d) loss of function. …”
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Systemic Inflammation Impairs Mood Function by Disrupting the Resting-State Functional Network in a Rat Animal Model Induced by Lipopolysaccharide Challenge by Xia Zhu, Mu-Huo Ji, Shu-Ming Li, Bin Li, Li Mei, Jian-Jun Yang

“…The purpose of the current study was to use resting-state functional magnetic resonance imaging (fMRI) to explore changes in the functional connectivity in a lipopolysaccharide- (LPS-) induced systemic inflammation animal model. …”
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Defatted chia (Salvia hispanica L.) flour peptides: Exploring nutritional profiles, techno-functional and bio-functional properties, and future directions by Etty Syarmila Ibrahim Khushairay, Salma Mohamad Yusop, Mohamad Yusof Maskat, Abdul Salam Babji

“…Recent studies have highlighted the techno-functional properties of DCF peptides, showing excellent solubility, water- and oil-absorption capacities, as well as emulsifying, foaming, and gelling abilities. …”
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Enhancing hydrogen evolution reaction using transition metal atoms on 6,6,12-graphyne: A DFT study by Motaghi Fatemeh, Mohammadi-Manesh Hossein

“…In this study, we present a theoretical design of transition metal (TM) anchored 6,6,12- graphyne (GY) based catalysts for the hydrogen evolution reaction (HER) using density functional theory (DFT). Our findings reveal that among all evaluated systems, cobalt single-atom catalyst (SAC) anchored on 6,6,12-graphyne exhibit the highest thermodynamic stability and superior HER catalytic performance, with a remarkably low ΔGH* value of 0.042 eV. …”
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Use of the Glycolipopeptid Biosurfactant Produced by <i>Lactiplantibacillus plantarum</i> Tw226 to Formulate Functional Cinnamon Bark Essential Oil Emulsions by Virginia M. Lara, María F. Gliemmo, Marisol Vallejo, María del Carmen García González, María del Carmen Alfaro Rodríguez, Carmen A. Campos

“…The antifungal activities of the three emulsions against <i>Candida tropicalis</i>, <i>Candida krusei</i>, and <i>Zygosaccharomyces bailii</i> did not change, regardless of the surfactant used, according to MIC values. In conclusion, a mixture of biosurfactant and Tween 80 or biosurfactant alone is an alternative for reducing or substituting synthetic surfactants in essential cinnamon bark oil emulsions, depending on their desired physical and functional properties. …”
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Increasing the smoking cessation success rate by enhancing improvement of self-control through sleep-amplified memory consolidation: protocol of a randomized controlled, functional... by Sarah Gerhardt, Michaela Kroth, Alexandra Seeger, Roland Schmitt, Heiner Fritz, Lorena Diring, Yury Shevchenko, Karen D Ersche, Gordon Feld, Sabine Vollstädt-Klein

“…Abstract Background Tobacco use disorder (TUD) remains a global health crisis characterized by high relapse rates despite extensive cessation efforts. …”
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Analytical solution of non-exponential decay in a simple resistor-capacitor circuit using the Lambert-Tsallis Wq function by L.A.B. Ramos, R.V. Ramos

“…In this work, using the Lambert-Tsallis Wq function, we present the analytical solution for the non-exponential decay in a simple electrical circuit composed by two resistors, two capacitors and a DC power supply. …”
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Comparison of sexual function scale scores in women according to the contraception method used as part of family planning strategy in Turkey by Banuhan Şahin, Görker Sel, Buğra Şahin, Şafak Hatırnaz

“…However, the contraceptive method used by women of reproductive age may affect their sexual function. …”
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Land Use Functions Serve as a Critical Tool for Advancing the Settlements Quality Assessment in Traditional Villages: A Case Study of Guizhou Province by Yan Wang, An Huang, Feier Wang, Zhe Cheng, Min Wang

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Comparing Cognitive Functions and Psychosocial Functioning of Euthymic Patients Having Bipolar Mood Disorder with Healthy Controls: A Cross-sectional Study by Divya Anidharan Rani, Shashwath M. Sathyanath, Ravichandra Karkal, Rohan Dilip Mendonsa, Anil Kakunje

“…Functioning assessment short test was used to assess psychosocial functioning. …”
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The Use of Virtual Reality to Improve Gait and Balance in Patients with Parkinson’s Disease: A Scoping Review by Rachel Surridge, Curt Stilp, Christen Johnson, Jason Brumitt

“…(1) Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that impairs balance and postural control, gait, overall motor function, and mood, and involves the gradual degradation of several physiologic systems. …”
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Altered functional connectivity density in the brains of hemodialysis end-stage renal disease patients: An in vivo resting-state functional MRI study. by Yan Shi, Chaoyang Tong, Minghao Zhang, Xiaoling Gao

“…The purpose of this study was to investigate the changes of global functional connectivity density (gFCD) in brains of ESRD patients undergoing hemodialysis using resting-state functional magnetic resonance imaging (re-fMRI).…”
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Relationship between β1-AA and AT1-AA and Cardiac Function in Patients with Hypertension Complicated with Left Ventricular Diastolic Function Limitation by Liang Wang, Xue-Bai Lv, Yu-Ting Yuan, Ning Wang, Hong-Ying Yao, Wen-Chao Zhang, Peng-Fei Yin, Xiao-Hui Liu

“…To investigate the association between β1 adrenergic receptor autoantibodies (β1-AA) and angiotensin II type-1 receptor autoantibodies (AT1-AA) and cardiac function in patients with hypertension complicated with left ventricular diastolic function limitation. …”
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Association between number of functional teeth and physical function among community-dwelling older adults: Korean Frailty and Aging Cohort Study by Nahyun Lim, Daehyun Lee, Seung-Yun Shin, Chang Won Won, Miji Kim

“…Multivariate linear and logistic regression models were used to evaluate the association between number of functional teeth and physical function. …”
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Sharp Bounds on Hankel Determinant of <i>q</i>-Starlike and <i>q</i>-Convex Functions Subordinate to Secant Hyperbolic Functions by Lifen Zhang, Zhigang Wang, Lei Shi

“…In the present paper, using the <i>q</i>-difference operator, we introduce two classes of <i>q</i>-starlike functions and <i>q</i>-convex functions subordinate to secant hyperbolic functions. …”
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Ciliary Functional Analysis in Chronic Rhinosinusitis with Polyps after Multimodal Intervention: Oral Corticosteroid, Functional Endoscopic Sinus Surgery, and Omalizumab Injection by Lionel Benchimol, Olivier Bouchain, Noemie Bricmont, Romane Bonhiver, Celine Kempeneers, Philippe Lefebvre, Anne-Lise Poirrier

“…Notably, this case report represents the first study investigating ciliary function using DHSV in a patient treated with omalizumab.…”
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The Functional Movement Screen for Injury Prediction in Male Amateur Football / Der Functional Movement Screen zur Verletzungsvorhersage im Männer-Amateurfußball by Schroeder J, Wellmann K, Stein D, BraumannKM

“…This study was aiming at investigating correlations between injuries of amateur male football players and the results of a Functional Movement Screen (FMS). Using an observational design, ten amateur teams of the fifth and sixth division (Deutscher Fuball-Bund) were examined by means of FMS scores prior to a tenweek off- and main- season observation period (July to September 2013). …”
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The changes in brain network functional gradients and dynamic functional connectivity in SeLECTS patients revealing disruptive and compensatory mechanisms in brain networks by Linfeng Song, Guangrong Wu, Jiaren Zhang, Benqing Liu, Xu Chen, Junjun Wang, Xiaoyu Gu, Binlin Tian, Yongzhe Li, Anjie Zhang, Xuejin Ma, Lin Jiang

“…BackgroundSelf-limited epilepsy with centrotemporal spikes (SeLECTS), a common childhood focal epilepsy syndrome, is linked to cognitive impairments and poorly understood neuropathological mechanisms.MethodsThis study explored dynamic functional connectivity (dFC) and functional gradients (FG) alterations in key brain networks using resting-state MRI (rs-MRI) data from 34 SeLECTS patients and 32 healthy controls (HCs).ResultsThe results revealed significant dFC changes between the Default Mode Network (DMN) and Sensorimotor Network (SMN) in SeLECTS patients compared to HCs. …”
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Fluoxetine does not impair motor function in patients with Parkinson's disease: Correlation between mood and motor functions with plasma concentrations of fluoxetine/norfluoxetine by Kostić Vladimir, Džoljić Eleonora, Todorović Zoran, Mijajlović Milija, Svetel Marina, Stefanova Elka, Dragašević Nataša, Petrović Igor, Milošević Milenko, Kovačević Ivan, Miljković Branislava, Pokrajac Milena, Prostran Milica

“…Plasma concentrations of Flu and norfluoxetine (NORFlu) were correlated with the results of selected motor function performance scores: The Unified Parkinsons Disease Rating Score (UPDRS), Finger Tapping Test (FTT) and Purdue Pegboard Test (PPT). …”
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Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level–dependent functional magnetic resonance imaging study in elderly adults by Annchen R. Knodt, James R. Burke, Kathleen A. Welsh‐Bohmer, Brenda L. Plassman, Daniel K. Burns, Stephen K. Brannan, Michael Kukulka, Jingtao Wu, Ahmad R. Hariri

“…Such ongoing clinical research can be advanced by developing a better understanding of how these drugs affect intermediate brain phenotypes associated with both AD risk and pathophysiology. Methods Using a randomized, parallel‐group, placebo‐controlled design in 55 healthy elderly volunteers, we explored the effects of oral, low‐dose pioglitazone, a thiazolidinedione with promitochondrial effects, on hippocampal activity measured with functional magnetic resonance imaging during the encoding of novel face–name pairs. …”
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