FUNCTIONS OF THE mTOR SIGNALING PATHWAY IN NORMAL ARTICULAR CARTILAGE CHONDROCYTES AND IN OSTEOARTHRITIS by E. V. Chetina, N. G. Kashevarova, E. P. Sharapova

“…This suggests that chondrocyte  metabolism undergoes the profound changes during cartilage resorption,  which are due to dysregulation of cell function. One of the major cellular metabolic regulators is the protein mTOR (mechanistic target of rapamycin) that controls cell growth, proliferation, protein biosynthesis and integrates extracellular signals from growth factors and hormones with amino acid availability and intracellular energy status. …”
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Fine-tuning protein language models to understand the functional impact of missense variants by Ali Saadat, Jacques Fellay

“…Elucidating the functional effects of missense variants is crucial yet challenging. …”
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Speaker differences in volitional voice modulation reflected in empathy and functional activation patterns. by Stella Guldner, Frauke Nees, Herta Flor, Carolyn McGettigan

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Protein post-translational modifications in serine synthetic pathway: functions and molecular mechanisms by Mincong Shu, Yuhan Liu, Jianbin Wang

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Digital Video Compression Using DCT-Based Iterated Function System (IFS) by Nevart A. Minas, Faten H. Al-Qadhee

“…The codec, storage systems and network needs resource utilization, so it becomes important to minimize the used memory space and time to distribute these videos over the Internet using compression techniques. …”
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Physical-Unclonable-Function-Based Secure and Anonymous User Authentication for Smart Homes by Hakjun Lee, Jihyeon Ryu

“…The proposed solution integrates bio-hash techniques for protecting user identity and physical unclonable functions to mitigate device capture attacks. Our scheme establishes a secure session key between the user, gateway, and sensor, providing protection against various known attacks from both internal and external adversaries. …”
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Modeling of Basic Processes of Labor Market Functioning and Development: Methodological and Practical Aspects by Zh. B. Kenzhin, Kh. U. Nursapina, Zh. Abzhanova, Zh. M. Bulakbay, T. K. Kuangaliyeva

“…Research methods: generalization, comparison, analysis and synthesis, induction and deduction, structural-logical analysis, monographic method, statistical modeling methods, machine learning methods, neural network modeling, fuzzy logic. The purpose of the article is to develop a methodological approach to the study of basic processes of functioning and development of the labor market under the conditions of digitalization. …”
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Dogs’ olfactory resting-state functional connectivity is modulated by age and brain shape by Asami Nakaimuki, Bernadett Paska, Laura V. Cuaya, Raúl Hernández-Pérez, Kalman Czeibert, Dóra Szabó, Eniko Kubinyi, Attila Andics

“…Dog olfactory brain networks have recently been mapped by anatomical measures, but functional connections remain unexplored. …”
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MRI-based insights into brain structural and functional alterations in schizophrenia treated with risperidone by Hangyu Li, Xinyue Chen, Shiji Peng, Ying Li, Rui Yu, Kaike Liao, Nian Liu

“…In addition, more potential methods such as DKI, DSI and brain covariance network have the opportunity to be used in the study of brain structure and function in the treatment of schizophrenia with risperidone in the future.…”
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Intrinsic Functional Connectivity Alterations of the Fusiform Face Area in Autism Spectrum Disorder by Natalia Kleinhans, Sarah F. Larsen, Annette Estes, Elizabeth Aylward

“…The FFA seed region was delineated in each participant using a functional localizer task. Whole brain analyses of FFA connectivity revealed increased connectivity between the right FFA and the vermis, sensorimotor cortex, and extended face-processing network in individuals with ASD compared to TD participants; the TD group did not demonstrate increased functional connectivity. …”
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Morphological, vascular, and functional changes in macular telangiectasia type 2 in Egyptian patients by Shaimaa Ibrahim Gafar, Hany Hamza, Ihab Abdelaziz, Rania G. Estawro, Shaymaa Hassan Salah

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The Effect of Transobturator Tape Surgery on Female Sexual Functions: A Systematic Review by Engin Yildirim, Nuriye Buyukkayaci Duman, Umit Gorkem, Ozgur Kan

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Ultralong Carbon Nanotube Yarns Integrated as Electronic Functional Elements in Smart Textiles by Ayelet Karmon, Ori Topaz, Raman Tandon, Andy Weck, Ortal Tiurin, Sheizaf Rafaeli, Zeev Weissman

“…These yarns enable the manufacturing of stable, workable structures, composed of a network of twisted fibers (tows), which are suitable for fabric integration. …”
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Metagenomic sequencing reveals the taxonomic and functional characteristics of rumen microorganisms in Dongliu buffalo by Wenwen Lu, Jinling Hua, Min Zhang, Longfei Yan, Huwei Zhao, Xiaokang Lv

“…Network analysis revealed Prevotella’s dominance in CAZymeme contributions and functional specialization in lignocellulose degradation pathways, suggesting sex-driven microbial adaptation to dietary fiber utilization.…”
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Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy. by James J Dowling, Andrew P Vreede, Sean E Low, Elizabeth M Gibbs, John Y Kuwada, Carsten G Bonnemann, Eva L Feldman

“…Myotubularin is a lipid phosphatase implicated in endosomal trafficking in vitro, but with an unknown function in vivo. Mutations in myotubularin cause myotubular myopathy, a devastating congenital myopathy with unclear pathogenesis and no current therapies. …”
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Altered cortical swallowing processing in patients with functional dysphagia: a preliminary study. by Sonja Suntrup, Inga Teismann, Andreas Wollbrink, Tobias Warnecke, Martin Winkels, Christo Pantev, Rainer Dziewas

“…Functional dysphagia is such a rare condition, whose pathogenetic mechanism is largely unknown. …”
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Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain by Minseok Kim, Sehwan Park, Haeyun Lee, Jimin Lee, Namsun Chou, Hyogeun Shin

“…In vivo experiments produce successful recordings from the motor cortex, somatosensory cortex, and deep structures such as the substantia nigra. Functional connectivity analysis also reveals strong correlations between the substantia nigra and motor cortex, confirming that the developed array can be used to accurately assess neural network dynamics in 3D space. …”
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Differences in the functional use of two migratory stopovers by humpback whales (Megaptera novaeangliae). by Raphael Mayaud, Joshua N Smith, David Peel, Craig Wilson, Wally Franklin, Tim Stevens, Susan Bengtson Nash

“…Therefore, contextualising the significance of Moreton Bay relative to a well-established stopover like Hervey Bay, can provide valuable insights into their functional roles within the broader migratory network, helping to inform targeted conservation efforts. …”
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Angle Estimation Based on Wave Path Difference Rate of Change Ambiguity Function by Jianye Xu, Maozhong Fu, Zhenmiao Deng

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PINK1 Loss of Function Selectively Alters the Mitochondrial‐Derived Vesicle Pathway by Charlotte L. Collier, Colleen Ruedi, Naomi J. Thorne, David A. Tumbarello

“…ABSTRACT Cell homeostasis and metabolic control require the efficient function of mitochondria and implementation of quality control pathways following damage. …”
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