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Identification of Important Modules and Hub Gene in Chronic Kidney Disease Based on WGCNA
Published 2022-01-01“…Chronic kidney disease (CKD) is an ongoing deterioration of renal function that often progresses to end-stage renal disease. …”
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Strandless rolling based on four-high modules in stands of continuous section mills
Published 2025-03-01“…Non-driven rolls are deforming and at the same time perform the function of the outlet mating reinforcement, ensuring the stability of the roll in the rolls. …”
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Least Squares Method and Least Modules Method for Finding Defects in Regular Images
Published 2025-03-01“…The first and second problems correspond to finding the best according to the criterion of least squares of regular and basic regular structures, and the third and fourth - the best according to the criterion of smallest modules of regular and basic regular structures. Methods of calculating gradients of smooth functions (LSM) and subgradients of non-smooth functions (LMM) for all four problems are described. …”
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Pan-genomic analysis of Cation/H+ exchanger (CAX) family variation in soybean reveals structural and functional insights into heavy metal stress response
Published 2025-10-01“…Our findings propose a TF-CAX regulatory module fine-tuning heavy metal stress adaptation, providing a foundational resource for soybean functional genomics and stress-resilient crop design.…”
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Functional activity and connectivity signatures of ketamine and lamotrigine during negative emotional processing: a double-blind randomized controlled fMRI study
Published 2024-10-01“…Investigating this modulation in relation to both the acute and sustained effects of ketamine on functional activity and connectivity during negative emotional processing should therefore provide novel insights. 75 healthy subjects were investigated in a double-blind, single-dose, randomized, placebo-controlled, parallel-group study with three treatment conditions (ketamine, lamotrigine pre-treatment, placebo). …”
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Doping the Buckminsterfullerene by Substitution: Density Functional Theory Studies of C59X (X = B, N, Al, Si, P, Ga, Ge, and As)
Published 2013-01-01“…The heterofullerenes C59X (X = B, N, Al, Si, P, Ga, Ge, and As) were investigated by quantum chemistry calculations based on density functional theory. These hybrid cages can be seen as doping the buckminsterfullerene by heteroatom substitution. …”
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Functional Annotation of Small Noncoding RNAs Target Genes Provides Evidence for a Deregulated Ubiquitin-Proteasome Pathway in Spinocerebellar Ataxia Type 1
Published 2012-01-01“…Thus, we identified and functionally annotated a plausible regulatory pathway that may serve as a potential target to modulate the outcome of neurodegenerative diseases.…”
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HEP14-activated PKC-ERK1/2 pathway boosts HEP14-empowered hADSCs for ovarian regeneration and functional restoration
Published 2025-08-01“…Transcriptome analysis reveals that HEP14 modulates gene expression profile in hADSCs, enhancing their regenerative capacity. …”
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A Multi-Functional Grid-Tied PV System Using a Split Source Inverter With Energy Management and Power Quality Improvement Features
Published 2025-01-01“…In this paper, split-source inverter (SSI) is proposed for multi-functional grid-connected (MFGC) application because it offers the better boosting capability with fewer components. …”
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1653
PKCα Phosphorylates FACI to Switch Its Function in Clathrin-mediated Endocytosis to a Presumed Role in Macropinocytosis in Intestinal and Hepatic CellsSummary
Published 2025-01-01“…Background & Aims: We previously identified a fasting- and CREB-H-induced (FACI) protein and defined its adaptor function in clathrin-mediated endocytosis. Both CREB-H and FACI are specifically expressed in the liver and intestine. …”
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Protective effects of polysaccharide of Atractylodes macrocephala Koidz and Jiawei Si-jun-zi Decoction on gut health and immune function in cyclophosphamide-treated chicks
Published 2025-07-01“…This study utilized a Cyclophosphamide (CTX)-induced gut injury model to explore the effects of Polysaccharide of Atractylodes macrocephala Koidz (PAMK) and the Jiawei Si-jun-zi Decoction (JSD) on alleviating gut injury and modulating immune function. The experimental results demonstrated that CTX significantly reduced the average daily gain (ADG) and antioxidant capacity of broiler chicks, disrupted intestinal barrier function, and induced gut microbiota dysbiosis. …”
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Evolution of the Soil Bacterial Community as a Function of Crop Management: A Metagenomic Study in Orange Tree (<i>Citrus sinensis</i>) Plantations
Published 2025-06-01“…These findings suggest that anti-weed netting not only influences the taxonomic composition of soil bacterial communities but also modulates their functional potential, with implications for sustainable agriculture in semi-arid environments. …”
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PIWI‐interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation
Published 2025-03-01“…However, the precise molecular pathways through which MIA disrupts neurovascular function remain largely unexplored. Here, we identify a novel MIA‐associated brain endothelial piRNA (MIABEPIR) involved in regulating BMEC function and BBB integrity. …”
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