Unraveling the Molecular Mechanisms of Synthetic Acetyl Hexapeptide in E-Cadherin Activation for Tissue Rejuvenation by Nikoleta Topouzidou, Androulla N. Miliotou, Danai Nodaraki, Eleftheria Galatou, Christos Petrou, Yiannis Sarigiannis

“…Specifically, the glycoprotein E-cadherin plays a crucial role in cellular adhesion and has shown promise in wound healing studies, although its broader cellular functions remain underexplored. Despite their widespread use, many cosmetic peptides lack genetic validation of their effects. …”
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The effects of kappa opioid agonist RU-1205 on local field potentials and behavior in the discriminative stimulus paradigm by K. Yu. Kalitin, O. Yu. Mukha, A. A. Spasov

“…The overall data suggest that RU-1205 is a functionally selective agonist of kappa-opioid receptors.…”
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Research on the Characteristics of Electrolytes in Integrated Carbon Capture and Utilization Systems: The Key to Promoting the Development of Green and Low-Carbon Technologies by Guoqing You, Yunzhi Li, Lihan Dong, Yichun Li, Yu Zhang

“…Ionic liquids (ILs) demonstrate unique advantages due to their tunability: imidazolium-based ILs improve formate selectivity to 85% via carboxylate intermediate formation, while amino-functionalized task-specific ILs (TSILs) achieve a 1:1 stoichiometric CO₂ absorption ratio. …”
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Illuminating <i>Cannabis sativa</i> L.: The Power of Light in Enhancing <i>C. sativa</i> Growth and Secondary Metabolite Production by S.M. Ahsan, Md. Injamum-Ul-Hoque, Shifa Shaffique, Akhtar Ayoobi, Md Atikur Rahman, Md. Mezanur Rahman, Hyong Woo Choi

“…Light is crucial for higher plants, driving photosynthesis and serving as a powerful sensory signal that profoundly modulates growth, development, physiological functions, hormone activation, and biochemical pathways. …”
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Disentangling the Immunomodulatory Effects of Vitamin D on the SARS-CoV-2 Virus by In Vitro Approaches by Ángela Alcalá-Santiago, Noelia M. Rodríguez-Martin, Justo Pedroche, Esther Molina-Montes

“…Vitamin D is a fat-soluble vitamin with multiple functions, including the modulation of the immune response, amongst others. …”
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HGF Aggravated Periodontitis-Associated Gut Barrier and Microbial Dysfunction: Implications for Oral–Gut Axis Regulation by Zhen Chen, Yang Zhong, Lu Chen, Weijia Liu, Chuyin Lin, Yannan Chen, Xinhong Wang

“…Notably, HGF also increased the enrichment of the periodontitis-associated pathogens (e.g., <i>Desulfovibrio</i> and <i>Streptococcus</i>) in the gut. Microbial functions, particularly metabolic pathways, were significantly altered by HGF when periodontitis occurred. …”
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Identification of signature genes and subtypes for heart failure diagnosis based on machine learning by Yanlong Zhang, Yanming Fan, Fei Cheng, Dan Chen, Hualong Zhang

“…In addition, we assessed the different subtypes of heart failure through unsupervised clustering, and investigations were conducted on the differences in the immunological microenvironment, improved functions, and pathways among these subtypes. Finally, a comprehensive analysis of the expression profile, prognostic value, and genetic and epigenetic alterations of four potential diagnostic candidate genes was performed based on The Cancer Genome Atlas pan-cancer database.ResultsA total of 295 differential genes were identified in the HF dataset, and intersected with the blue module gene with the highest correlation to HF identified by weighted correlation network analysis (r = 0.72, p = 1.3 × 10−43), resulting in a total of 114 key HF genes. …”
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LncRNA FLG-AS1 inhibits esophageal squamous cell carcinoma by regulating the miR-23a-3p/HOXD10 axis by Zhigao Zhang, Fucheng Zhang, Chuan Xue, Xiaoling Song, Yaojun Wang

“…Long non-coding RNAs (lncRNAs) have been proven to be severely dysregulated in EC, but the functions of more lncRNAs still need to be explored. …”
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Energy-Efficient Aggressive Duty-Cycling of V-Band Power Amplifiers by Maximilian Gottfried Becker, Marco Gunia, Diego Mendez, Frank Ellinger

“…In addition to implementing the core functionality, a design goal for modern circuits is reduced energy consumption. …”
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Neutrophil extracellular traps-related genes contribute to sepsis-associated acute kidney injury by Tang Shaoqun, Yu Xi, Wang Wei, Luo Yaru, Lei Shaoqing, Qiu Zhen, Yang Yanlin, Sun Qian, Xia Zhongyuan

“…Additionally, the biological functions of the hub genes were analyzed with single sample gene set enrichment analysis. …”
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Altered IgG <i>N</i>-Glycosylation at Onset of Type 1 Diabetes in Children Is Predominantly Driven by Changes in the Fab <i>N</i>-Glycans by Branimir Plavša, Najda Rudman, Flemming Pociot, Olga Gornik

“…<b>Background</b>: <i>N</i>-glycosylation is a post-translational modification involving the attachment of oligosaccharides to proteins and is known to influence immunoglobulin G (IgG) effector functions and even antigen binding. IgG contains an evolutionarily conserved <i>N</i>-glycosylation site in its fragment crystallizable (Fc) region, while during V-D-J recombination and somatic hypermutation processes it can also obtain <i>N</i>-glycosylation sites in its antigen binding fragment (Fab). …”
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Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. by Jun Ikari, Amy J Nelson, Jannah Obaid, Alvaro Giron-Martinez, Kumiko Ikari, Fumihiko Makino, Shunichiro Iwasawa, Yoko Gunji, Maha Farid, Xingqi Wang, Hesham Basma, Dawn Demeo, Carol Feghali-Bostwick, Olaf Holz, Klaus Rabe, Xiangde Liu, Stephen I Rennard

“…In COPD, lung fibroblast repair functions are altered in multiple ways, including extracellular mediator release. …”
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On the Control of the Technical Condition of Elevator Ropes Based on Artificial Intelligence and Computer Vision Technology by A. V. Panfilov, A. R. Yusupov, A. A. Korotkiy, B. F. Ivanov

“…The developed PAC VIC laboratory sample consisted of a hardware part, a video stream processing module, communicator for the server connectivity, specially designed software, and a client mobile application. …”
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Regulation of mesenchymal stem cell-derived exosomes on helper T cells in periodontitis by WEN Yuqi, GUO Shujuan, DING Yi

“…In addition, microRNAs exhibit immunoregulatory functions: periodontal ligament stem cell-derived exosomes contain miRNA-155-5p, which targets sirtuin-1 to suppress Th17 cell differentiation. …”
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First Report on Microbial-Derived Polydeoxyribonucleotide: A Sustainable and Enhanced Alternative to Salmon-Based Polydeoxyribonucleotide by Doobyeong Chae, Sae-Woong Oh, Yoon-Seo Choi, Dae-Jung Kang, Chun-Woong Park, Jongsung Lee, Won-Sang Seo

“…The novel approach of utilizing microbial-derived PDRN opens new avenues for therapeutic applications in oxidative stress management, tissue regeneration, and immune modulation, paving the way for a paradigm shift in PDRN sourcing and functionality.…”
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Whole-Body Cryotherapy Reduces Systemic Inflammation in Healthy Adults: Pilot Cohort Study by Elizabeth Chun, Richard Joseph, Rachele Pojednic

“…Biomarkers were modeled as linear functions of W-BC sessions received in the month prior to blood draw. …”
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Exploring the Role of N-WASP in Breast Cancer Metastasis through Mass Spectrometry and Potential Signalling Pathway Analysis by Rhiannon Yannan Yu, Wenguo Jiang, Tracey Martin

“…In cancer biology, the role of N-WASP in cell motility and metastasis is of particular interest, yet its specific functions in breast cancer remain to be fully understood. …”
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Potential targets of heparin during progression and metastasis of malignant neoplasms by V. V. Malashchenko, I. A. Khlusov, K. A. Yurova, O. G. Khaziakhmatova, N. M. Todosenko, L. S. Litvinova

“…To prevent its consequences, the direct and indirect anticoagulants, especially heparin and its derivatives, are actively used. Biological functions and structural features of heparin make it a potential universal platform of a drug development for broad application, including oncology. …”
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Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis by Iranna Kotturshetti, Basavaraj Vastrad, Veena Kori, Chanabasayya Vastrad, Shivakumar Kotrashetti

“…Gene ontology (GO) enrichment analysis and REACTOME pathway enrichment analysis were carried out to identify potential biological functions and pathways of the DEGs. Protein-protein interaction network, module, micro-RNA (miRNA)-hub gene regulatory network, transcription factor (TF)-hub gene regulatory network, and drug-hub gene interaction network analysis were performed to identify the hub genes, miRNA, TFs, and drug molecules. …”
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Information and measuring system for geometric and motion parameters determination of industrial products by their video images by Yurii Podchashynskyi, Oksana Luhovykh, Anna Polianska, Volodymyr Nevmerzhytskyi

“…In addition, in the automatic mode, the software is supplied with video image normalisation and segmentation thresholding functions for more accurate measurements. A series of measurements have been made in manual and automatic modes. …”
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