Do Statins Affect Viral Infections Encountered by International Travelers? by Chinmay T. Jani, Christian Mouchati, Nour Abdallah, Ruchi Jani, Loukas Kakoullis, Lin H. Chen

“…In addition to their well-established effectiveness in lowering total cholesterol, LDL, and triglycerides, statins have been described to have immunomodulatory and anti-inflammatory properties and have been associated with improved endothelial functions. Given the common use of statins, we sought to evaluate the effect of statins on some viral infections encountered by residents in tropical areas or by international travelers. …”
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Lipid-based nano-carriers for the delivery of anti-obesity natural compounds: advances in targeted delivery and precision therapeutics by Daniel Ejim Uti, Esther Ugo Alum, Item Justin Atangwho, Okechukwu Paul-Chima Ugwu, Godwin Eneji Egbung, Patrick M. Aja

“…These advanced delivery systems improve bioactive retention, enable controlled release, and enhance therapeutic action on adipose tissue and metabolic pathways. Additionally, functionalized and stimulus-responsive nanocarriers present innovative approaches for precision obesity treatment. …”
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Bioinformatic prediction, annotation and experimental validation of conserved microRNAs in Lactuca sativa Linn by Shehnaz Shair Qambrani, Muhammad Naeem Shahwani, Iftekhar Ahmed Baloch, Shahjahan Shabir Ahmed Rana, Asma Abro

“…The presence of three precursor miRNA clusters suggested coordinated regulatory functions. The identification of conserved miRNAs and their associated protein targets opens avenues for understanding the molecular mechanisms underlying regulatory processes in this economically significant leafy vegetable and the knowledge gained from this research lays the groundwork for potential applications in modulating miRNAs to control desired features in lettuce, thereby contributing to the improvement of this essential crop.…”
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Development and research of uninterruptible power supply system for networks with supply voltage up to 24 V by I. M. Sharov, O. A. Demin, A. A. Sudakov, A. D. Yarlykov

“…Dual redundancy of the module monitoring the built-in battery parameters is used to ensure the reliability and safety of system functioning. …”
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Production of [18F]DPA-714, [18F]fallypride and [18F]LBT-999 using iMiDEV, a fully automated microfluidic platform: towards clinical radiopharmaceutical production by Salla Lahdenpohja, Camille Piatkowski, Laurent Tanguy, Bertrand Kuhnast

“…Abstract Background Positron emission tomography is widely used to study biological processes without disrupting normal physiological functions. Traditional radiotracer synthesis and industrial market is focused on producing large batches of 18F-labelled tracers, especially [18F]FDG. …”
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The role of surfactant proteins SP-A and SP-D in viral infection: a focus on COVID-19 by O. S. Kharlamovа, K. Yu. Nikolaev, Yu. I. Ragino

“…An immune response to invasion of viral pathogens is an integral part of maintaining the physiological functioning of the bronchopulmonary system and effective gas exchange. …”
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Bioinformatics analysis and preliminary validation of autophagy-related genes in asthma disease by Bo Sun, Huiman Huang, Ran An, Bing Wei, Xiaozhe Yue

“…Five hub genes were identified by PPI network analysis and key module construction. These genes showed good diagnostic value for asthma. …”
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OPTIMIZATION STRATEGIES AND COMPUTATIONAL MODELING IN THE DESIGN AND PERFORMANCE EVALUATION OF GREEN POROUS OIL ADSORBENT MATERIALS by Haoran Zhang, Sagdat Mederbekovna Tazhibayeva

“…The surface area, pore size, surface functionalization, and hydrophobicity index of green porous adsorbents were examined. …”
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Single-cell transcriptome atlas reveals mitophagy dynamics in acute chemical injury model and the role of MSCs transplantation by Sang Luo, Fang Wu, Xiaojun Yang

“…Abstract Background and purpose Mitochondrial autophagy, also referred to as mitophagy, clears damaged mitochondria and has dual functions in disease development and liver homeostasis in response to liver pathologies. …”
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Managing Arsenic Pollution from Soil–Plant Systems: Insights into the Role of Biochar by Qitao Su, Zhixuan Du, Xinyi Huang, Muhammad Umair Hassan, Faizah Amer Altihani

“…Arsenic toxicity negatively affects plant morph-physiological and biochemical functioning and upsurges the generation of reactive oxygen species (ROS), which negatively affect cellular structures. …”
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Optimum Conditions for Pyomelanin Production and Characterization from Local Isolates of Pseudomonas aeruginosa by Naz Fuad H. Khorshid, Nisreen Hadi Odaa

“…Background: Nowadays, there is increased interest in the biosynthesis of microbial melanin related to their numerous biological functions and applications in many fields, especially in medical fields, including immune-modulating, antimicrobial antibiotic, antiviral antivenin, anticancer, antitumor activity, and anti-biofilm activity. …”
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Large overlap in neutrophil transcriptome between lupus and COVID-19 with limited lupus-specific gene expression by Tomas Mustelin, Alison Bays, Rayan Najjar, Noga Rogel, Jose Mario Bello Pineda, Xiaoxing Wang, Megan Tran

“…In contrast, 118 genes demonstrated statistically significant alterations exclusive to SLE, including 28 genes that were differentially expressed in opposite directions in the two diseases.Conclusions The substantial overlap between neutrophil responses in SLE and COVID-19 suggests that the unknown cause of SLE is functionally similar to a viral infection and drives a similar immune activation and type I interferon response. …”
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The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner. by S S Antipov, M N Tutukina, E V Preobrazhenskaya, F A Kondrashov, M V Patrushev, S V Toshchakov, I Dominova, U S Shvyreva, V V Vrublevskaya, O S Morenkov, N A Sukharicheva, V V Panyukov, O N Ozoline

“…Dps is a multifunctional homododecameric protein that oxidizes Fe2+ ions accumulating them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing bacterial nucleoid upon starvation and performs some other functions. During the last two decades from discovery of this protein, its ferroxidase activity became rather well studied, but the mechanism of Dps interaction with DNA still remains enigmatic. …”
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Effect of ratio Pluronic P123 and gelatin on titania as a catalyst in methylene blue degradation by Maria Ulfa, Indriyani Pangestuti

“…Gelatin, employed as a biotemplate alongside Pluronic P123, effectively modulates the physicochemical characteristics of titania. …”
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Drug hypersensitivity: Mechanisms and opportunities of laboratory diagnostics by N. V. Bychkova

“…Due to dysregulation which is a key factor of allergic inflammation, the mechanisms of normalization for impaired immune regulation should be understood, thus offering new strategies for personalized treatment, e.c., modulating the regulatory cell functions, aiming for control of the drug hypersensitivity reactions.…”
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THE MODEL OF DETECTING LEGISLATION VIOLATORS AT THE STATE BORDER USING FUZZY LOGIC INFERENCE by Oleksandr S. Androshchuk, Oleksandr V. Mikhaylenko

“…Construction of membership functions of terms "low", "medium", "high", used to assess linguistic variables, by using the method of statistical analysis expert information. …”
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Self-supervised multi-stage deep learning network for seismic data denoising by Omar M. Saad, Matteo Ravasi, Tariq Alkhalifah

“…The first sub-network serves as a strong denoiser with a small number of neurons, effectively attenuating seismic noise; in contrast, the second sub-network functions as a signal-add-back model, using a larger number of neurons to retrieve some of the signal that was not preserved in the output of the first sub-network. …”
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Evidence for a pro-proliferative feedback loop in prostate cancer: the role of Epac1 and COX-2-dependent pathways. by Uma Kant Misra, Salvatore Vincent Pizzo

“…<h4>Conclusion</h4>We show that Epac1, a downstream effector of cAMP, functions as a pro-inflammatory modulator in prostate cancer cells and promotes cell proliferation and survival by upregulating Ras-MAPK, and PI 3-kinase-Akt-mTOR signaling.…”
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Depression and anxiety in childhood-onset systemic lupus erythematosus: prevalence, associated factors, and impact on quality of life and family by Pitsamai Duangmala, Watchareewan Sontichai

“…Providing psychological counseling and prompt referral to psychiatrists could enhance HRQOL and family functioning.…”
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Adaptation responses to salt stress in the gut of Poecilia reticulata by Hyerim Lee, Hyunjae Yeo, Jihye Park, Keunsoo Kang, Sun-Ju Yi, Kyunghwan Kim

“…In contrast, many genes related to the innate immune system (such as Tnfaip6) were downregulated, suggesting a shift toward the prioritization of osmoregulatory functions over immune responses. Interestingly, the differential expression of adaptation genes was linked to variations in epigenetic modifications and transcription factor activity. …”
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