The Lyme disease bacterium, Borrelia burgdorferi, stimulates an inflammatory response in human choroid plexus epithelial cells. by Derick Thompson, Jordyn Sorenson, Jacob Greenmyer, Catherine A Brissette, John A Watt

“…The main functions of the choroid plexus (CP) are the production of cerebral spinal fluid (CSF), the formation of the blood-CSF barrier, and regulation of immune response. …”
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THERMOELECTRIC SEMICONDUCTOR DEVICES FOR THERMAL STABILISATION OF REA POWERFUL TRANSISTORS by T. A. Ismailov, A. R. Shakhmaeva, A. M. Ibragimova

“…The developed devices have the following functions: the thermoelectric battery sections of the thermoelectric battery will be sequentially disconnected depending on the electrical signals from the temperature sensors to which the solid phase of the working substance has moved. …”
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Hepatocyte‐derived extracellular vesicles regulate liver regeneration through a negative feedback mechanism by Mina McGinn, Christopher Rabender, Ross Mikkelsen, Vasily Yakovlev

“…Upon uptake by the recipient cells, EVs can significantly modulate their biological functions. In the present study, using in vivo and in vitro models, we demonstrate that hepatocyte proliferation and liver regeneration are regulated by EVs secreted by hepatocytes into the bloodstream. …”
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The Switching of the Type of a ROS Signal from Mitochondria: The Role of Respiratory Substrates and Permeability Transition by Alexey G. Kruglov, Anna B. Nikiforova

“…Under certain conditions, O₂⁻ can leave the mitochondrial matrix and perform signaling functions beyond mitochondria. In this work, we studied the kinetics of the release of O₂⁻ and H₂O₂ from isolated mitochondria upon mPTP opening and the modulation of the metabolic state of mitochondria by the substrates of respiration and oxidative phosphorylation. …”
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Adaptive Ensemble Learning Model-Based Binary White Shark Optimizer for Software Defect Classification by Jameel Saraireh, Mary Agoyi, Sofian Kassaymeh

“…Abstract Software dominates modern enterprises, affecting numerous functions. Software firms constantly experiment with new methodologies to define and assess software quality to stay competitive and ensure excellence. …”
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GPR139 agonist and antagonist differentially regulate retrieval and consolidation of fear memory in the zebrafish by Nisa Roy, Satoshi Ogawa, Sachiko Tsuda, Ishwar S. Parhar

“…However, how GPR139 signaling in the habenula modulates such adaptive behavioral responses remains unsolved. …”
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Effects of input modality and second-language vocabulary proficiency on processing of Japanese compound verbs by Qichao Song, Xiaodong Fei, Norio Matsumi

“…Third, upon visual presentation, the processing of different types of compound verbs tended to shift from decomposed to holistic processing depending on the absence of grammatical and semantic functions in the first or second verbs; conversely, upon auditory presentation, a tendency toward decomposed processing prevailed across all types of compound verbs. …”
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COL11A1 is Downregulated by miR-339-5p and Promotes Colon Carcinoma Progression by Weizhi Liu, Ke Meng

“…COL11A1 upregulation promoted colon carcinoma cell functions, while overexpressing miR-339-5p evidently attenuated the promotion. …”
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Contributions of Pathobiological and Translational Science to Understanding and Managing Ischemic Heart Disease: Progress, Impediments, and Future Directions by L. Maximilian Buja, MD

“…Nevertheless, opportunities for further progress against ischemic heart disease have come from new perspectives and approaches, including (1) recognition that functionally significant ischemic heart disease can result from microvascular dysfunction or epicardial coronary atherosclerosis; (2) rapid diagnosis of AMI subtypes through application of the Universal Definition of Myocardial Infarction based on high-sensitivity cardiac troponin measurements; (3) the Canadian Cardiovascular Society classification of AMI based on stages of tissue injury severity, as detected by advanced imaging; (4) implementation of the occlusion vs nonocclusion MI paradigm to prompt aggressive management of all ST-segment elevation MI and the one-third of non–ST-segment elevation MI with total occlusion; and (5) implementation of the Early Heart Attack Care program, which emphasizes prodromal symptom recognition to prevent AMI progression.…”
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Development of an efficient mid-field wireless power transmission system for biotelemetric IoT medical devices by Naeem Abbas, Abdul Basir, Izaz Ali Shah, Usman Rizqi Iman, Hyoungsuk Yoo

“…In this demonstration, the rectenna’s output was used to power an IoT-based temperature sensor-integrated communication module, showcasing the real-time functionality and capability of the proposed WPT system for wirelessly powering IoTMDs.…”
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PERFORMANCE ANALYSIS FOR DIRECTION-FINDING CIRCULAR ANTENNA ARRAY by Svyatoslav V. Ballandovich, Grigory A. Kostikov, Liubov M. Liubina, Mikhail I. Sugak

“…The solution to the coupled integral equations is obtained using the Galerkin method with piecewise sinusoidal current distribution and with an arbitrary number of basis functions for eight- and four-element circular antenna array. …”
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miR‐32533 Reduces Cognitive Impairment and Amyloid‐β Overload by Targeting CREB5‐Mediated Signaling Pathways in Alzheimer's Disease by Li Zeng, Zhongdi Cai, Jianghong Liu, Kaiyue Zhao, Furu Liang, Ting Sun, Zhuorong Li, Rui Liu

“…Bioinformatics and confirmatory experiments revealed that miR‐32533 had a novel 23‐base sequence with minimal coding potential, functioning within the Drosha ribonuclease III (Drosha)/Dicer 1, ribonuclease III (Dicer)‐dependent canonical pathway and identifiable via northern blot. miR‐32533 was abundantly brain‐distributed and downregulated in diverse AD‐related models, including APP/PS1 and five familial AD (5×FAD) mouse brains and AD patient plasma. …”
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Structural brain network organization in children with prenatal alcohol exposure by Xiaoyun Liang, Claire E. Kelly, Chun-Hung Yeh, Thijs Dhollander, Stephen Hearps, Peter J. Anderson, Deanne K. Thompson

“…Complex structural network analyses can provide insight into the neurobiological underpinnings of these functions, as they may be sensitive for characterizing the effects of PAE on the brain. …”
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Early secretory antigen target of 6-kDa of Mycobacterium tuberculosis inhibits macrophage apoptosis and host defense via TLR2 by Lin Zhang, Fang Fang, Danrui Liu, Geman Xia, Tong Feng, Jingzhu Lv, Jinying Qi, Tengteng Li, Hui Liu, Tao Xu, Fengjiao Wu, Chuanwang Song, Wei Li, Xiaojing Wang, Xianyou Chang, Hongtao Wang, Ting Wang, Zhongqing Qian

“…In parallel, our in silico analysis of differentially expressed genes in dendritic cells (DCs) infected with Bacille Calmette-Guérin (BCG) strains, with or without the region of difference-1 (RD1) gene, strongly suggests that ESAT-6, located within the RD1 region, modulates host defense functions and apoptosis in DCs during BCG infection. …”
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Immunomodulatory and anticancer effects of moringa polyherbal infusions: potentials for preventive and therapeutic use by Wamidh H. Talib, Wamidh H. Talib, Hadeel Shaher Al Junaidi, Heba K. Alshaeri, Moudi M. Alasmari, Moudi M. Alasmari, Rawan W. Hadi, Ahmad Riyad Alsayed, Douglas Law

“…The Nitro Blue Tetrazolium Assay and Neutral Red Method were used to assess the effects of each extract on macrophage phagocytic and pinocytosis functions. Lymphocyte proliferation was also tested.ResultsThe anti-proliferative activity of Moringa-saffron showed the strongest anti-proliferative effect on T47-D and EMT6/P, with IC50 values of 1.14 ± 0.05 and 1.65 ± 0.27 mg/ml, respectively. …”
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Acousto-Electric Conversion Fiber Networks via Regional Activation of Schwann Cell-Derived Exosomes for Neurogenic Bone Regeneration by Weiwei Yi, Xiaoyu Han, Fan Wang, Qiuyu Tang, Huzhe Liu, Bo Liao, Jieliang Shen, Juan Wang, Wenguo Cui, Dingqun Bai

“…Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, with exosomes derived from Schwann cells regionalized in bone injury tissue playing a crucial role in this process. …”
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A splice‐switching antisense oligonucleotide targeting APP reduces accumulation of α‐synuclein in a mouse model of Parkinson's disease by Rijwan U. Ahammad, Brian Spencer, Bao Quach, Sahar Salehi, Robert A. Rissman

“…Findings support APP modulation as a potential strategy for synucleinopathies.…”
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Integrating multi-omics and experimental techniques to decode ubiquitinated protein modifications in hepatocellular carcinoma by Haikun Yang, Yuan Chen, Yuan Chen, Zheng Zhou, Yanjing Wang, Peng Li, Yang Li

“…Ubiquitination not only supports proliferation and anti-apoptotic functions within tumor cells but also promotes tumor progression by modulating the activity of immune and stromal cells. …”
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The role of autophagy in cancer: from molecular mechanism to therapeutic window by Pooya Jalali, Arvin Shahmoradi, Amir Samii, Radman Mazloomnejad, Mohammad Reza Hatamnejad, Anwaar Saeed, Afshin Namdar, Zahra Salehi

“…To this end, interventions aimed at modulating the fate of tumor cells by controlling or inducing autophagy substrates necessitate meticulous monitoring of these mediators’ functions within the tumor microenvironment to make informed decisions regarding their activation or inactivation. …”
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Colder environments are associated with a greater cancer incidence in the female population of the United States by Ankit Sharma, Tanu Sharma, Mahaveer S Panwar, Devesh Sharma, Rashmi Bundel, Ryan T Hamilton, James A Radosevich, Chandi C Mandal

“…Similarly, environmental temperature modulates many biological functions. To study the effect of environment temperature on cancer incidence, the US population was selected. …”
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