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13761
Long non-coding RNAs and autophagy: dual drivers of Hepatocellular carcinoma progression
Published 2025-08-01“…This review describes how autophagy contributes to HCC at different stages, outlines the dual functions of lncRNAs as oncogenic drivers or tumor suppressors, and illustrates their integration into key signaling networks of autophagy (e.g., PI3K/AKT/mTOR, AMPK, Beclin-1). …”
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13762
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Published 2023-02-01“…Measurements of orthologous coronavirus spike proteins implied the interaction was functionally restricted to SARS-CoV-2 by accessibility. …”
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13763
Chronic unpredictable stress exacerbates surgery-induced sickness behavior and neuroinflammatory responses via glucocorticoids secretion in adult rats.
Published 2017-01-01“…Stress-induced GCs played a pivotal role in enhancing surgery-induced neuroinflammatory processes by modulation of microglia functions.…”
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13764
Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients – A randomized co...
Published 2025-01-01“…Psychomotor and cognitive functions improved with L-theanine and GABA (P = 0.0001) and decreased with alprazolam (P = 0.0001). …”
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13765
Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression
Published 2025-05-01“…Low expression of circ_0000043, lymph node metastasis, and FIGO were all unfavorable factors threatening the prognosis of CC. circ_0000043 overexpression markedly inhibited the proliferation, migration, and invasion of cancer cells. miR-590-5p is a direct target miRNA of circ_0000043. miR-590-5p mimic prominently resisted the altered cellular functions induced by circ_0000043. Conclusion Patients with low circ_0000043 expression have poor prognosis as it fuels CC progression by boosting cancer cell proliferation, migration, and invasion via miR-590-5p. …”
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13766
Fuzzy control system of multioperational machine status
Published 2017-06-01“…The paper presents the key aspects of constructing a management system for the state of multi-operation computer-controlled machines based on the information-control module of e-Mind Machine and the apparatus of fuzzy sets and fuzzy logic. …”
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13767
Homo academicus in Transition
Published 2024-12-01“…The material was then systematized according to the qualitative principle, singling out the most important changes that the interviewees experienced themselves or observed in their surroundings, in respect to two basic functions of university: teaching and research. The theoretical-methodological postulation of this approach is that the members of an academic community share the so-called “academic culture” and that the characteristics of this culture and the ways it changes (or remains the same) may only be approached by focusing on individuals and the modes in which they change their social actions, interpret and modulate the newly acquired culture, due to the pressures of the changing conditions. …”
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13768
The bovine oviductal environment and composition are negatively affected by elevated body energy reserves.
Published 2025-01-01“…Thus, elevated BER may lead to oviductal insulin resistance, affecting normal functioning and, probably, embryo metabolism during early development, thus impacting gestational rates in these animals.…”
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13769
A Digital Controller for Reactivity Monitoring and Power Control
Published 2023-01-01“…Two abovementioned independent functions were combined in an Artix-7 FPGA board for determining reactivity values by solving the point reactor kinetics equations with six delayed neutron groups and for stabilizing the reactor power at preset levels by determining the unbalance voltage signal to control the automatic control rod. …”
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13770
THERMOELECTRIC SYSTEM FOR PROVIDING A HEAT REGIME FOR MODULAR ELECTRONIC EQUIPMENT
Published 2020-01-01“…An important additional point for the functioning of the thermoelectric cooling device is the necessity of ensuring the effective removal of heat from the hot junctions of the thermoelectric module without which it is impossible to use the proposed system.…”
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13771
Effects of cryptotanshinone in treatment of polycystic ovary syndrome in rats: a systematic review and meta-analysis
Published 2025-05-01“…Cryptotanshinone appears to restore both reproductive and metabolic functions, including the regulation of body weight, ovarian morphology, hormone levels, and gene expression. …”
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13772
TRIM55 suppresses inflammatory response after spinal cord injury by accelerating the ubiquitination and degradation of TLR4
Published 2025-05-01“…Results The findings revealed that TRIM55 was downregulated both in vitro and in vivo. Functionally, TRIM55 inhibited apoptosis and reduced the expression of pro-inflammatory cytokines in LPS-stimulated PC12 cells. …”
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13773
Modelling of triplet proximity effects in conically magnetized NbN/Ho/NbN Josephson junctions
Published 2025-07-01“…We use self-consistent solutions of the Usadel equations to investigate the energy-resolved density of states (DOS) and superconducting critical temperature ( $$T_c$$ T c ) as functions of ferromagnetic layer thickness, misorientation angles, interfacial roughness, and phase differences between the superconducting NbN layers. …”
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13774
Distribution of the impact of monetary and fiscal policy instruments by technological modes and sectors of the economy
Published 2023-07-01“…The subject of the study is the impact of monetary and fiscal policy instruments on the functioning of the structural elements of the economy, represented by sectors and technological structures. …”
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13775
YOLO-LSM: A Lightweight UAV Target Detection Algorithm Based on Shallow and Multiscale Information Learning
Published 2025-05-01“…Different from previous work on medical detection, this study tailors YOLO-LSM for UAV-based small object detection by introducing targeted improvements in feature extraction, detection heads, and loss functions, achieving better adaptation to aerial scenarios.…”
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13776
An insulin-sensitive Drosophila insulin-like receptor mutant remodels methionine metabolism to extend lifespan.
Published 2025-06-01“…Type I and II mutants overlap in many pathways but also produce distinct transcriptomic profiles that include differences in innate immune and reproductive functions. In metabolomic analyses, the KID mutant dInr353 reprograms methionine metabolism in a way that phenocopies dietary methionine restriction, in contrast to canonical mutants which are characterized by upregulation of the transsulfuration pathway. …”
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13777
Pancancer analysis of DNA damage repair gene mutations and their impact on immune regulatory gene expression
Published 2025-05-01“…These genes were clustered and categorized using Metascape, an integrative bioinformatics tool that applies enrichment-based analysis to group functionally related genes into clusters. The clustered genes were further validated through a literature review and the GeneCards database. …”
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13778
Switchable and Tunable Terahertz Metamaterial Absorber with Ultra-Broadband and Multi-Band Response for Cancer Detection
Published 2025-02-01“…The proposed metamaterial exhibits dual functionalities depending on the VO<sub>2</sub> phase state. …”
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13779
Improved MViTv2-T model for insulator defect detection
Published 2025-01-01“…Additionally, it introduces the stage query recollection method, which integrates high-level and low-level module queries within each stage, along with various experimentation on integration functions between the two. …”
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13780
Effects of supplemental feeding on the fecal bacterial communities of Rocky Mountain elk in the Greater Yellowstone Ecosystem.
Published 2021-01-01“…Multiple laboratory studies have demonstrated the importance of the gut microbiome for extracting and synthesizing nutrients, modulating host immunity, and many other vital host functions, but these relationships can be disrupted by dietary perturbation. …”
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