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13681
Evaluation of nonlinear optical properties of neutron irradiated polymethyl methacrylate and their recovery over time
Published 2025-12-01“…The structural and optical properties of PMMA change due to neutron irradiation, which may have adverse effects on its functionality in these applications. In this study, the effect of reactor neutron irradiation on structural and nonlinear optical properties of PMMA has been experimentally investigated. …”
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13682
Nuclear basket nucleoporin MoNup50 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae
Published 2025-05-01“…In this study, we functionally characterized MoNup50, a nuclear pore-associated protein. …”
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13683
Post-Translational Modifications of Proteins Orchestrate All Hallmarks of Cancer
Published 2025-01-01“…Post-translational modifications (PTMs) of proteins dynamically build the buffering and adapting interface between oncogenic mutations and environmental stressors, on the one hand, and cancer cell structure, functioning, and behavior. Aberrant PTMs can be considered as enabling characteristics of cancer as long as they orchestrate all malignant modifications and variability in the proteome of cancer cells, cancer-associated cells, and tumor microenvironment (TME). …”
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13684
Molecular insights into the interaction between cytochrome c and carbon nanomaterials
Published 2024-12-01“…However, the consequences of this interaction on the cyt c functions are controversial. Here the mechanism of interaction of carbon nanoparticles (CNPs), chosen as model of redox-active CNMs, with cyt c has been studied with the aim to shed light into these discrepancies. …”
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13685
VSMCs in atherosclerosis: Implications on the role of inflammation and extracellular matrix remodelling
Published 2025-08-01“…Therefore, the main functions of VSMCs in atherosclerosis will be influenced, including the production of extracellular matrix (ECM) proteins and the maintenance of atherosclerotic plaque stability. …”
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13686
Direct extraction of respiratory information from pulse waves using a finger-inspired flexible pressure sensor system
Published 2025-05-01“…Specifically, we fabricated a highly sensitive (11,847.24 kPa−1) flexible pressure sensor using a screen printing process, which is capable of functioning beyond 70,000 cycles. Additionally, we engineered a bidirectional long short-term memory (BiLSTM) neural network, enhanced with a residual module, to classify various respiratory states including slow, normal, fast, and simulated breathing. …”
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13687
Photoacclimation and Photoadaptation Sensitivity in a Global Ocean Ecosystem Model
Published 2025-06-01“…A series of global ocean ecosystem simulations were conducted to assess these latter sensitivities: alternative photoacclimation schemes implicitly modulated investments in light harvesting versus photodamage avoidance and other cellular functions. …”
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13688
Bisphenol A Does Not Mimic Estrogen in the Promotion of the In Vitro Response of Murine Dendritic Cells to Toll-Like Receptor Ligands
Published 2017-01-01“…Our results suggest that estrogen promotes immune responses by increasing DC activation, with a preferential effect on TLR9 over TLR4 stimulation, and highlight the influence of estrogens in DC cultures, while BPA does not mimic estrogen in the DC functions that we tested.…”
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13689
Synbiotic combination of Bifidobacterium longum BB536 and lactulose improves the presenteeism of healthy adults associated with aromatic lactic acids - A single-arm, open-label stu...
Published 2025-12-01“…Gut microbiota and their metabolites are crucial for metabolic regulation, immunomodulation, and brain and mental functions via the brain-gut axis. Synbiotics offer an effective strategy for improving gut health by modulating gut microbiota, leading to improved physical and mental health. …”
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13690
Small Modular AUV Based on 3D Printing Technology: Design, Implementation and Experimental Validation
Published 2024-01-01“…The composition and functions of key units are described in detail, and an autonomous depth-tracking control strategy is formulated. …”
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13691
Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence
Published 2025-05-01“…Abstract Cerebral asymmetry, fundamental to various cognitive functions, is often disrupted in neuropsychiatric disorders. …”
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13692
The solute carrier family 11 transporters: a bridge between iron homeostasis and tumor biology
Published 2025-07-01“…In this review, we provide an overview of the physiological functions of SLC11 transporters in iron metabolism and their pathological roles in cancer biology. …”
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13693
Transcription factors containing both C2H2 and homeobox domains play different roles in Verticillium dahliae
Published 2024-09-01“…In this study, we systematically characterized the functions of seven C2H2-homeobox transcription factors in V. dahliae. …”
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13694
Bovine PMN responses to extracellular vesicles released by Besnoitia besnoiti tachyzoites and B. besnoiti-infected host cells
Published 2024-12-01“…Emerging evidence indicates that extracellular vesicles (EVs) modulate PMN effector functions, such as ROS production or NET formation. …”
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13695
Association between the attentional network efficiency and change of direction speed ability in young male Indian footballers
Published 2025-01-01“…These findings attempted to fill the knowledge gap by highlighting the importance of the attentional network functions in modulating CODS ability. The outcomes can benefit football training by implementing ANT-I test in sports-specific settings and for screening purposes. …”
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13696
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate
Published 2024-12-01“…Background: COVID-19 reduces lung functionality causing a decrease of blood oxygen levels (hypoxemia) often related to a decreased cellular oxygenation (hypoxia). …”
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13697
Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice
Published 2024-12-01“…Resveratrol (RES), a natural compound with anti-inflammatory and cholesterol metabolism regulatory properties, has been shown to influence the maturation and inflammatory functions of DCs. However, its relationship with cholesterol metabolism remains unclear. …”
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13698
Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer
Published 2025-08-01“…Furthermore, using transcriptome data from 23 CRC patients, we constructed an immune cell infiltration matrix to deeply explore the biological functions associated with LNM. Eventually, using the characteristics of the gut microbiota associated with LNM, we developed random forest (RF) and multilayer perceptron (MLP) machine learning models to predict the LNM status of CRC patients. …”
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13699
Single-Cell RNA Transcriptomics and Multi-omics Analyses Reveal the Clinical Effects of Acupuncture on Methadone Reduction
Published 2025-01-01“…Our findings revealed that acupuncture may activate the defense response to viruses, with altered immune cell functions in classical monocytes correlating with clinical responses to reduced methadone doses. …”
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13700
Salidroside inhibits melanin synthesis and melanoma growth via mTOR and PI3K/Akt pathways
Published 2025-07-01“…This study aimed to explore the effect of salidroside on PI3K/Akt/mTOR in melanoma, which plays a role in regulating melanogenesis.MethodsNetwork pharmacology was predicted that salidroside may exert an anti-melanoma effect through modulating melanin synthesis functions and signaling pathways. …”
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