A HYPOTHESIS ABOUT THE FUNCTION OF NEUROMELANIN AS A BASIC INFORMATION CARRIER IN THE DEVELOPED HUMAN BRAIN (COMPL., COR.LAST) by Vasil Hadzhiiliev, Dimcho Dimov, Diana Kiselova

“…The most common vision about the function of neuromelanin is correlated withits neuroprotective properties at present. …”
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Neuroprotective Effects of Functionalized Hydrophilic Carbon Clusters: Targeted Therapy of Traumatic Brain Injury in an Open Blast Rat Model by Parasuraman Padmanabhan, Jia Lu, Kian Chye Ng, Dinesh Kumar Srinivasan, Kumar Sundramurthy, Lizanne Greer Nilewski, William K. A. Sikkema, James M. Tour, Thomas A. Kent, Balázs Gulyás, Jan Carlstedt-Duke

“…The application of a newly developed biologically compatible catalytic superoxide dismutase mimetic carbon-based nanocluster, a poly-ethylene-glycol-functionalized hydrophilic carbon cluster (PEG-HCC), was tested post-blast to modulate the components of the TBI process. …”
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A single-cell atlas of bladder cancer unveils dynamic cellular composition and endothelial functional shifts during progression by Hongjian Song, Guixiang Xie, Yaowei Li, Xiaowei Hu, Zongzheng Yang, Yubo Zhao, Qing Shi, Haonan Li, Ziyi Liu, Zhihao Yin, Ziqi Wang, Zhichao Tong, Wanhai Xu

“…Methods Public single-cell RNA sequencing (scRNA-seq) datasets from 47 BC patients were analyzed to characterize endothelial cell heterogeneity and functional states across NMIBC and MIBC. Computational tools such as CellChat were applied to reconstruct cell–cell communication networks, focusing on pathways related to angiogenesis, immune crosstalk, and ECM remodeling. …”
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Functional and Therapeutic Roles of Plant-Derived Antioxidants in Type 2 Diabetes Mellitus: Mechanisms, Challenges, and Considerations for Special Populations by Vicente Javier Clemente-Suárez, Alexandra Martín-Rodríguez, Ana Isabel Beltrán-Velasco, Alejandro Rubio-Zarapuz, Ismael Martínez-Guardado, Roberto Valcárcel-Martín, José Francisco Tornero-Aguilera

“…Recent developments, such as nanoencapsulation, synergistic functional food formulations, and microbiome-targeted strategies, have shown promise in enhancing efficacy. …”
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Effects of 3D-printed exosome-functionalized brain acellular matrix hydrogel on neuroinflammation in rats following cerebral hemorrhage by Aobo Zhang, Boyu Sun, Chengrui Nan, Lulu Cong, Zongmao Zhao, Liqiang Liu

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Effects of probiotics and synbiotics oral supplementation on thyroid function in adults: a grade-assessed systematic review and meta-analysis by Mehdi Karimi, Reyhane Rabiei, Kimia Kazemi, Reyhaneh Bagheri Motlagh, Omid Asbaghi

“…Abstract Background and aim Evidence suggests that the gut microbiota may have a potential impact on thyroid function, given the gut-thyroid axis and the microbiome’s involvement in nutrient absorption, immune modulation, and hormone metabolism. …”
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Functional T cell response to COVID-19 vaccination with or without natural infection with SARS-CoV-2 in adults and children by Evana Akhtar, Rakib Ullah Kuddusi, Md. Tanvir Talukder, Md. Jakarea, Md. Ahsanul Haq, Md. Shamim Hossain, Maya Vandenent, Mohammad Zahirul Islam, Rashid U. Zaman, Abdur Razzaque, Protim Sarker, Rubhana Raqib

“…Here, we aimed to compare COVID-19 vaccine-induced functional T cell response between adults and children with and without previous SARS-CoV-2 infection. …”
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Application of the Multiple Exp-Function, Cross-Kink, Periodic-Kink, Solitary Wave Methods, and Stability Analysis for the CDG Equation by Haifa Bin Jebreen, Yurilev Chalco-Cano

“…It is investigated that the equation exhibits the trigonometric, hyperbolic, and exponential function solutions. We first construct a combination of the general exponential function, periodic function, and hyperbolic function in order to derive the general periodic-kink solution for this equation. …”
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A study on the function of methionine in growth, immunity, antioxidant, endoplasmic reticulum stress and apoptosis of largemouth bass (Micropterus salmoides) by Hualiang Liang, Dongyu Huang, Mingchun Ren, Lu Zhang, Haifeng Mi, Ahmed Mohamed Aboseif, Chunyu Xue, Jiaze Gu

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Hidden features: CD36/SR-B2, a master regulator of macrophage phenotype/function through metabolism by Yuge Chen, Xuejia Zhang, Xuejia Zhang, Shengbin Huang, Shengbin Huang, Maria Febbraio

“…Emerging data show that alterations in the microenvironment can recast metabolic pathways and modulate macrophage function, with the potential to be leveraged for therapeutic means. …”
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Finite Difference Analysis of 2D Stress Wave Propagation in Two Dimensional Functionally Graded Ceramics-Metals Composites by Ali Amiri, Hossein Rahmani

“…Firstly, the governing equations of wave propagation in the functionally graded plane strain media were derived in Cartesian coordinate. …”
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Mechanistic and therapeutic insights into the function of different cell death modalities in rheumatoid arthritis: emphasis on the crosstalk with non-coding RNAs by Jianting Wen, Jianting Wen, Jianting Wen, Jian Liu, Jian Liu, Jian Liu, Lei Wan, Lei Wan, Lei Wan, Fanfan Wang, Fanfan Wang

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Functional induction of the cystine-glutamate exchanger system Xc(-) activity in SH-SY5Y cells by unconjugated bilirubin. by Pablo J Giraudi, Cristina Bellarosa, Carlos D Coda-Zabetta, Paolo Peruzzo, Claudio Tiribelli

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Cloning and characterization of apolipoprotein A-IV (ApoA-IV) from Oreochromis niloticus involved in immune defense functions by Yongxiong Huang, Xuyan Tan, Jiamin Feng, Zhiqiang Zhang, Kwaku Amoaha, Berchie Asiedu, Yu Huang, Jichang Jian

“…Apolipoprotein A-IV (ApoA-IV) is a multifunctional protein that participates in a broad spectrum of biological processes, including the modulation of immune function. Nevertheless, the specific roles of ApoA-IV in the immune response to acute bacterial infections in Nile tilapia (Oreochromis niloticus) are yet to be fully elucidated. …”
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Functional products fortified with probiotic LAB isolated from Egyptian dairy sources showed hypolipidemic effects in Albino rats. by Amira M G Darwish, Marwa G Allam, Enaam S Shokery, Eman H E Ayad

“…Biological food industry has increased economic importance of new Lactic Acid Bacteria (LAB) with functional aspects such as health promoting and enhanced sensorial traits. …”
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Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression by Efrat Oron, Tamir Tuller, Ling Li, Nina Rozovsky, Daniel Yekutieli, Sigal Rencus‐Lazar, Daniel Segal, Benny Chor, Bruce A Edgar, Daniel A Chamovitz

“…We are using Drosophila as a model system to elucidate the function of this important complex. Transcriptome data were generated for four csn mutants, sampled at three developmental time points. …”
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Regulatory T Cell Function Is Not Affected by Antisense Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer (PPMO)-Mediated TMPRSS2 Truncation by Sandra Gunne, Fiona K. Sailer, Lucas Keutmann, Marie Schwerdtner, Hong M. Moulton, Eva Böttcher-Friebertshäuser, Susanne Schiffmann

“…<b>Methods:</b> TMPRSS2 was truncated in human Tregs using a splice-modulating PPMO. Effects on Treg function were analyzed by evaluation of surface marker and transcription factor expression, cytokine secretion, and effector cell suppression capability. …”
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Deciphering the multifaceted role of double-stranded RNA sensor protein kinase R: pathophysiological function beyond the antiviral response by Jiyoon Chung, Yerim Lee, Jimin Yoon, Yoosik Kim

“…This review explores PKR function in various pathological and physiological contexts in the absence of viral stimuli. …”
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Merging π-molecular functions achieved through homogeneous liquid-liquid blending of solvent-free alkyl-π liquids by Zhenfeng Guo, Chengjun Pan, Akira Shinohara, Takashi Nakanishi

“…When modulating function by adding solid dopants, the dopant molecules have poor solubility, leading to insoluble aggregates and inconsistencies in properties such as luminescent color. …”
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The regulatory functions of G protein-coupled receptors signaling pathways in B cell differentiation and development contributing to autoimmune diseases by Yongqi Shao, Yang Mei, Yixin Tan, Ming Yang, Haijing Wu

“…All of this is inextricably linked to the differentiation, development, migration, and functional regulation of B cells in the human immune response. …”
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