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13421
Emergence of a synergistic scaffold in the brains of human infants
Published 2025-05-01“…Previously it has been shown that synergy is crucial for many complex brain functions and cognition, however, it remains unknown how and when the large number of discrete neurons evolve into the unified system able to support synergistic interactions. …”
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13422
The Potential of Red Blood Cells in Regenerative Medicine: A Paradigm Shift in Cellular Therapy
Published 2025-05-01“…This review explores the biological functions of RBCs in regenerative medicine, their potential contributions to PRP and BMAC, and the challenges associated with their inclusion. …”
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13423
Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses
Published 2025-04-01“…This review provides comprehensive insights into the recent advances in understanding the functions of SMs in plant defense against abiotic and biotic stresses, emphasizing their regulatory networks and biosynthetic pathways. …”
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13424
The Hallmarks of Ageing in Human Immunodeficiency Virus Infection and the Impact of Antiretroviral Therapy on Telomeres: A Molecular Perspective
Published 2025-04-01“…Ageing is a complex and unavoidable physiological process which, in simple terms, consists of a progressive deterioration in the functionality of cells, tissues and organs, culminating in an increased risk of developing chronic pathologies. …”
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13425
Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis
Published 2025-07-01“…However, the precise types of neurons involved and whether they possess additional metabolic regulatory functions remain to be elucidated. The study reveals that corticotropin‐releasing hormone (CRH) neurons in the APC (APCCRH neurons) are activated by a leucine‐deficient diet to modulate brown adipose tissue thermogenesis and that they regulate body temperature in response to leucine deprivation. …”
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13426
Transient cortical beta-frequency oscillations associated with contextual novelty in high density mouse EEG
Published 2025-01-01“…However, it was also found that the cortex in general, is highly modulated by environmental novelty. This data further suggests the retrosplenial cortex is an important hub for distinguishing environmental context and highlights the diversity of functions for beta oscillations across the brain, which can be observed using high-density EEG.…”
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13427
A Testing Framework for Joint Communication and Sensing in Synthetic Aperture Radars
Published 2025-01-01“…This paper introduces a novel testing framework that enables comprehensive evaluation of ISAC functionalities without the operational constraints of real-time tests. …”
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13428
A Novel Fractional Slot Concentrated Winding Yokeless Counter-Rotating Dual-Rotor Permanent Magnet Machine
Published 2025-01-01“…The proposed machine shows counter-rotating functionality and flexibility in rotational speed and torque. …”
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13429
CPK28-mediated Ca2+ signaling regulates STOP1 localization and accumulation to facilitate plant aluminum resistance
Published 2025-06-01“…Abstract The transcription factor SENSITIVE TO PROTON RHIZOTOXICITY 1 (STOP1) functions as a crucial integrator of plant responses to various stresses, including aluminum (Al) stress. …”
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13430
Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies
Published 2025-02-01“…It also highlights the biological functions of PARdU in DNA damage repair, signaling pathways, and metabolic regulation, with a focus on its therapeutic potential in cancer treatment. …”
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13431
Fe-deficiency-induced chlorosis 1 is essential for chloroplast iron transport and homeostasis under continuous light conditions in Arabidopsis
Published 2025-07-01“…Iron supplementation alleviates these phenotypes. FIC1 functionally complements iron transport defects in fet3fet4 yeast and enhances iron uptake in Xenopus oocytes. …”
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13432
NLRP3 activation induces BBB disruption and neutrophil infiltration via CXCR2 signaling in the mouse brain
Published 2025-05-01“…Abstract NLRP3 is an intracellular sensor molecule that affects neutrophil functionality and infiltration in brain disorders such as experimental autoimmune encephalomyelitis (EAE). …”
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13433
Exploring the cancerous nexus: the pivotal and diverse roles of USP39 in cancer development
Published 2025-05-01“…This review comprehensively summarizes the structural characteristics and molecular functions of USP39, emphasizing its pivotal role in the regulation of cellular processes. …”
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13434
Characterization of Holmium-Doped Fiber Using AOM and Considering Pair-Induced Quenching and Fiber Length
Published 2024-11-01“…A standard acousto-optic modulator controls the output power of the ytterbium-doped fiber laser operating at 1134.5 nm and serving as a pump source of the holmium-doped fiber under test. …”
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13435
How Do Glycine‐Induced Bent Structures Influence Hierarchical Nanostructuring and Suprastructural Handedness in Short Peptide Assembly?
Published 2025-04-01“…Abstract Despite the multiple roles of flexible and achiral Gly in regulating protein architectures and functions, its high flexibility is seldom exploited as a structural modulator in the design of self‐assembling peptides. …”
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13436
Emerging mechanisms and implications of m6A in CVDs: potential applications of natural products
Published 2025-06-01“…In this review, we summarized the biological functions of m6A modification and discussed the potential mechanisms and processes of m6A modification in various CVDs; we also summarized the research progress of natural products modulating m6A modification in the treatment of CVDs. …”
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13437
Lactic acid bacteria act as potent interventions in improving hyperuricemia: a review
Published 2025-04-01“…Lactic acid bacteria (LAB), generally recognized as safe (GRAS) probiotics, have been shown to alleviate symptoms associated with gastrointestinal disorders such as irritable bowel syndrome and inflammatory bowel disease while supporting overall bodily functions and health. Recently, LAB has emerged as a potentially safe, cost-effective and efficient treatment for HUA. …”
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13438
A Sub‐Diffraction‐Limit Dimension All‐Plasmonic Optical Memory Using Non‐Linear Photochromism
Published 2025-07-01“…By utilizing SPPs, reversible Write/Erase functions are achieved through multiphoton excitation, modulating the photostationary state of DAE. …”
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13439
Comparison of short-term and long-term effects of peroral L-carnitine intake: clinical implications of elevated TMAO levels in cardiovascular complications
Published 2025-02-01“…Also, it can be recruited with the aim of improving physical and cognitive functions in athletes and the elderly. Despite these benefits, long-term LC administration has been associated to cardiovascular risks due its conversion to trimethylamine-N-oxide (TMAO) by the gut microbiota. …”
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13440
Faecalibacterium prausnitzii enhances intestinal IgA response by host-microbe derived inecalcitol in colitis
Published 2025-07-01“…Results F. prausnitzii markedly ameliorated colitis by alleviating intestinal inflammation and barrier dysfunction, with significantly decreased abundance of pro-inflammatory taxa (Enterococcus, Desulfovibrio, Escherichia-Shigella, and Enterorhabdus) and increased abundance of Lachnospiraceae NK4A136_group. Functions related to intestinal immune network for IgA production pathway were up-regulated shown by transcriptomics and KEGG pathway analysis. …”
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