Biomarker identification associated with M2 tumor-associated macrophage infiltration in glioblastoma by Xue-yuan Li, Zhi-yun Yu, Hong-jiang Li, Dong-ming Yan, Chao Yang, Xian-zhi Liu

“…The immune landscape of patients with GBM was examined by evaluating immune cells, functions, evasion scores, and checkpoint genes.ResultsAnalysis of scRNA-seq and bulk-seq data revealed 107 genes linked to M2 TAMs. …”
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Off-targets effects of CNO on somatosensory and anxiety-related behaviors in rats by Xuan Li, Juan Yao, Lian-lin Zeng, Jia Huang, Xiao-qian Jiang, Jin-he Xu, Bing Wu, Hong-li Li, Ke-hui Hu

“…Designer receptors exclusively activated by designer drugs (DREADDs) are a powerful chemogenetic tool for controlling targeted cell populations and manipulating brain functions. As a typical chemogenetic actuator in DREADD systems, clozapine-N-oxide (CNO) is widely utilized in neurobiological and pharmacological research. …”
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Enhanced motivated behavior mediated by pharmacological targeting of the FGF14/Nav1.6 complex in nucleus accumbens neurons by Nolan M. Dvorak, Paul A. Wadsworth, Guillermo Aquino-Miranda, Pingyuan Wang, Douglas S. Engelke, Jingheng Zhou, Nghi Nguyen, Aditya K. Singh, Giuseppe Aceto, Zahra Haghighijoo, Isabella I. Smith, Nana Goode, Mingxiang Zhou, Yosef Avchalumov, Evan P. Troendle, Cynthia M. Tapia, Haiying Chen, Reid T. Powell, Timothy J. Baumgartner, Jully Singh, Leandra Koff, Jessica Di Re, Ann E. Wadsworth, Mate Marosi, Marc R. Azar, Kristina Elias, Paul Lehmann, Yorkiris M. Mármol Contreras, Poonam Shah, Hector Gutierrez, Thomas A. Green, Martin B. Ulmschneider, Marcello D’Ascenzo, Clifford Stephan, Guohong Cui, Fabricio H. Do Monte, Jia Zhou, Fernanda Laezza

“…Abstract Protein/protein interactions (PPI) play crucial roles in neuronal functions. Yet, their potential as drug targets for brain disorders remains underexplored. …”
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Does transcutaneous auricular vagus nerve stimulation alter pupil dilation? A living Bayesian meta-analysis by Ipek Pervaz, Lilly Thurn, Cecilia Vezzani, Luisa Kaluza, Anne Kühnel, Nils B. Kroemer

“…Background: Transcutaneous vagus nerve stimulation (tVNS) has emerged as a promising technique to modulate autonomic functions, and pupil dilation has been recognized as a promising biomarker for tVNS-induced monoaminergic release. …”
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The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study by Zhihan Fang, Zhihan Fang, Liyao Xie, Jing Wang, Junyi Li, Yirui Pan, Lei Chen, Shuyi Cao, Qi Zhou, Shaobin Li, Chao Zhang, Li Li

“…Dual luciferase assays indicated that FEV functions as a transcriptional repressor of SLC7A11; BS treatment altered FEV expression, thereby promoting SLC7A11 expression and facilitating the nuclear import of reduced glutathione. …”
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Research on a machine vision-based electro-killing pheromone-baited intelligent agricultural pest monitoring method by Guozhi Li, Zhengbo Liu, Zhengbo Liu, Zelin Feng, Jun Lyu, Bin Li, Guo Chen, Qing Yao

“…This system incorporates automated functions for pest trapping, killing, counting, and clearing, thereby achieving complete automation in the monitoring of pests attracted by sex pheromones.…”
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COMPARATIVE ASSESSMENT OF PAIN AND LIFE QUALITY IN THE PATIENTS AFTER OPEN AND VIDEO-ASSISTED LOBECTOMY FOR LUNG CANCER by R. I. Yurin, E. V. Levchenko, V. A. Gluscheko, A. E. Mikhnin, S. M. Ergnyan, L. V. Gorokhov, N. E. Levchenko, N. V. Khandogin

“…When using the questionnaires of SF-36 (U = 8,742.50; p < 0.05) and EORTC QLQ-C30 (U = 3,759.00; p < 0.05) and the special module of QLQ-LC13 for lung cancer (U = 4,243.00; p < 0.05), the obtained data also indicated the better life quality and functions, reduction of pathologic manifestations versus open surgical access. …”
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Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma by Jing Yang, Xiuxia Lu, Qiyan Cai, Mengmeng Liu, Tianliang Xia, Dongchun Hong, Liyuan Le, Xinke Zhang, Xing Zhang

“…Conclusions In conclusion, TACC2 is an important regulator of the immune response in STS, functioning as a tumor suppressor and a modulator of response to PD-1 blockade. …”
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CME Velocity Field Calculation Model Based on an Unsupervised Transformer Optical Flow Network by Qingyang Chen, Hong Lin, Zhenping Qiang, Hui Liu, Kaifan Ji, Zhenhong Shang

“…The network comprises a multiscale feature extraction module and a coarse-to-fine global optical flow calculation module. …”
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Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota by Cheng Wang, Siyu Wei, Bojing Liu, Fengqin Wang, Zeqing Lu, Mingliang Jin, Yizhen Wang

“…In addition, the MFD significantly accelerated the maturation of the gut microbiota of neonates and increased the abundance of gut Lactobacillus and the microbial functions of amino acid-related enzymes and glucose metabolism on the weaning day. …”
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Mitochondrial Transplantation: A Novel Therapeutic Approach for Treating Diseases by Xinglu Miao, Pei Jiang, Zhaoping Wang, Weihua Kong, Lei Feng

“…This review provides a comprehensive analysis of the multifaceted roles of mitochondria in health and disease, highlighting their central functions in energy production, antioxidant defense, calcium signaling, apoptosis regulation, and mitochondrial homeostasis maintenance. …”
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An Extremely Pseudo‐Plastic, Organic Crystal‐Based Concentric‐Ring‐Resonator Coupled Optical Waveguide by Avulu Vinod Kumar, Deepak Manoharan, Ankur Khapre, Soumyajit Ghosh, Rajadurai Chandrasekar

“…Subsequently, an HDBP optical waveguide is integrated with the CRR, resulting in the development of the organic crystal‐based optical filter. The modulation observed in optical modes’ wavelengths and their intensities in the waveguide when coupled with CRR shows optical filter functionality. …”
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Volume electron microscopy for genetically and molecularly defined neural circuits by Nobuhiko Ohno, Fuyuki Karube, Fumino Fujiyama

“…These advancements are expected to reveal mechanisms for processing adaptive changes in specific neural circuits that modulate brain functions.…”
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Ashwagandha and stress by Weronika Sobota, Przemysław Piskorz, Katarzyna Zemsta, Michał Zwoliński, Mateusz Tyniec, Kamal Morshed

“…Numerous studies conducted on both animals and humans confirm its beneficial effects on mental and physical health, including improvement of cognitive functions, sleep quality and emotional well-being. …”
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LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition by Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub

“…Functionally, LKB1 loss enhances proliferation and survival through SIK2 inhibition and upregulation of the sodium/calcium (Na+/Ca2+) exchanger SLC8A1. …”
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A Neural Device Inspired by Neuronal Oscillatory Activity with Intrinsic Perception and Decision‐Making by Congtian Gu, Guoliang Ma, Mengze Zhang, Hu Shen, Liaoyuan Pu, Yanhe Song, Shilong Yan, Dakai Wang, Kaixian Ba, Bin Yu, Zhiwu Han, Luquan Ren

“…This is accomplished using a single interface, which reduces data transmission, simplifies functionality, and eliminates the need for an external power supply. …”
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Trifunctional Sialylation‐Based SF‐ZIF@NA Hydrogel for Selective Osteoclast Inhibition and Enhanced Bone‐Vessel Regeneration in Osteoporotic Bone Defects by Zhengrong Chen, Wenxin Yang, Yong Tang, Qianqian Dong, Kui Huang, Jiulin Tan, Jie Zhang, Juan Cai, Qixiu Yu, Qijie Dai, Jianzhong Xu, Shuquan Guo, Ce Dou, Fei Luo

“…By enzymatically removing sialic acid, SF‐ZIF@NA prevents precursor osteoclasts (pOCs) from fusing into bone‐resorbing mature osteoclasts (mOCs), thereby preserving pOCs and their anabolic functions. Additionally, the hydrogel releases Zinc ion (Zn2⁺) in response to acidic conditions, promoting osteogenesis and angiogenesis. …”
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Flexible Glass Hybridized Colloidal Quantum Dots for Gb/s Visible Light Communications by Caroline Foucher, Mohamed Islim Sufyan, Benoit Jack Eloi Guilhabert, Stefan Videv, Sujan Rajbhandari, Ariel Gomez Diaz, Hyunchae Chun, Dimali A. Vithanage, Graham A. Turnbull, Ifor D. W. Samuel, Grahame Faulkner, Dominic C. O'Brien, Harald Haas, Nicolas Laurand, Martin D. Dawson

“…VLC is an emerging technology that uses white and/or colored light from LEDs to combine illumination and display functions with the transmission of data. The flexible glass/CQD format addresses the issue of limited modulation speed of typical phosphor-converted LEDs while enhancing the photostability of the color converters and facilitating their integration with the μLEDs. …”
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Eveningness and distinctness of the circadian rhythm in men are related to altered neural responses to gain and loss by Patrycja Scislewska, Michal Rafal Zareba, Julia Lengier, Aaron E. Schirmer, Piotr Bebas, Iwona Szatkowska

“…Abstract Circadian rhythmicity is considered to be one of the factors modulating the functions of the brain’s motivational system. …”
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Baicalein inhibits NLRP3 inflammasome activation and mitigates placental inflammation and oxidative stress in gestational diabetes mellitus by Yao Jun, Pan Jiaying, Jiang Qiaoying, Wang Hui, Zhao Yiqi

“…Baicalein, a flavonoid derived from the roots of Scutellaria baicalensis Georgi, exhibits various biological functions and has been implicated in the modulation of several diseases. …”
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