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13341
Integration of Climate Change and Ecosystem Services into Spatial Plans: A New Approach in the Province of Rimini
Published 2025-04-01“…The results highlight priority areas where climate adaptation and ecological functions converge, enabling targeted interventions. …”
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13342
Bioelectronic Hydrogels: Exemplifying the Synergy Between Biopolymers and Conjugated Polymers
Published 2025-08-01“…Subsequently, recent advancements in biopolymer‐based conductive hydrogels are discussed, with a focus on their fabrication method and ability to modulate specific cell functions. Finally, the advancements in self‐healing hydrogel bioelectronics are summarized, focusing on the variety of self‐healing mechanisms and the corollaries for enhanced bioelectronic longevity.…”
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13343
Elucidating ATP’s role as solubilizer of biomolecular aggregate
Published 2024-10-01“…Proteins occurring in significantly high concentrations in cellular environments (over 100 mg/ml) and functioning in crowded cytoplasm, often face the prodigious challenges of aggregation which are the pathological hallmark of aging and are critically responsible for a wide spectrum of rising human diseases. …”
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13344
Piezoelectric ion gated organic electrochemical transistors for efficient vibration sensing and on-site amplification
Published 2025-05-01“…We validate their functionality in mechanomyography, speech recognition, and mechanocardiography using microscale Piezo-IGTs. …”
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13345
Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association
Published 2025-07-01“…These methods often assume that AF2 relies on evolutionary couplings to predict alternative protein conformations, but they perform poorly on fold-switching proteins, which remodel their secondary structures and modulate their functions in response to cellular stimuli. …”
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13346
Computer Vision as a Tool to Support Quality Control and Robotic Handling of Fruit: A Case Study
Published 2024-10-01“…This system was developed with a Raspberry Pi 5 to capture images of the fruit using a PiCamera module 3. After detecting the object, a command is sent to a Universal Robotics UR3e robotic arm via Ethernet cable, using Python code that integrates company functions and functions developed specifically for this application. …”
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13347
Porcine reproductive and respiratory syndrome virus NSP5 exploited UBE2L6 to promote viral replication via antagonising host RLRs and ISGylation
Published 2025-07-01“…The ubiquitin–proteasome system (UPS) and ISGylation both play roles in modulating host innate immunity. Within this process, ISG15-conjugating enzyme E2L6 (UBE2L6) functions as an E2 ubiquitin/ISG15-conjugating enzyme, which is crucial for the enzymatic cascades of UPS and ISGylation. …”
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13348
A comparative analysis of three pharmacovigilance system assessment tools.
Published 2025-01-01“…These instruments are designed to evaluate the functionality and performance of national regulatory authorities within the context of their respective pharmacovigilance systems.…”
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13349
Monitoring of clinical signs of intravenous infusion patients with ZigBee wireless technology
Published 2022-04-01“…In this article, based on ZigBee module, automatic control of drip rate, abnormal alarm, real-time liquid crystal display of infusion progress, and other functions are realized without manual intervention. …”
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13350
Robust quantitative assessment of collagen fibers with picrosirius red stain and linearly polarized light as demonstrated on atherosclerotic plaque samples.
Published 2021-01-01“…Collagen is an important component in maintaining structural integrity and functionality of tissues and is modulated in various biological processes. …”
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13351
CD8 T cell dynamics and immune cell trafficking in ZIKV infection: implications for neuroinflammation and therapy
Published 2025-07-01“…This review explores the dual roles of CD8 T cells during ZIKV infection, emphasizing both their antiviral functions and their potential to drive neuroinflammation. …”
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13352
Ofd1 controls dorso-ventral patterning and axoneme elongation during embryonic brain development.
Published 2012-01-01“…Thus, the present study identifies Ofd1 as a developmental disease gene that is critical for forebrain development and ciliogenesis in embryonic life, and indicates that Ofd1 functions after docking and before elaboration of the axoneme in vivo.…”
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13353
Ligands for Intestinal Intraepithelial T Lymphocytes in Health and Disease
Published 2025-01-01“…This review provides a detailed examination of the ligands present in the intestinal epithelia and the corresponding receptors expressed on T-IELs, including T cell receptors (TCRs) and non-TCRs, as well as how these ligand-receptor interactions influence T-IEL functions under both steady-state and pathological conditions. …”
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13354
Analysis of the Dynamics of a Cubic Nonlinear Five-Dimensional Memristive Chaotic System and the Study of Reduced-Dimensional Synchronous Masking
Published 2024-01-01“…Based on the above, an image to be transmitted is modulated into a one-dimensional array and then subjected to the fractional and cyclic operations and combined with the linear encryption and decryption functions and the chaotic masking technique, the simple encryption and decryption of the image processes are realized.…”
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13355
Design and Simulation of Single Input Double Output Coupled Inductor Boost Converter with Bisection Method for Independent Home Application
Published 2024-12-01“…This paper proposed a converter design that functions as a voltage booster, increasing the input voltage while supplying two load outputs from a single voltage input using only one switch. …”
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13356
The Role of <i>SLPI</i> Gene-Mediated Inflammation in Osteoarthritis
Published 2025-06-01“…In this work, a comprehensive review of SLPI-mediated inflammation in OA, its biological functions, and its association with OA is described, providing a foundation for future investigations into its potential therapeutic use. …”
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13357
Development and Efficiency Analysis of Dual Active Bridge Converter Employing SiC Devices Using TMS 320F280039
Published 2025-01-01“…This analysis provides substantial perspectives toward the actual functionality of these systems through contrasts of simulation results with hardware-based results from the real world.…”
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13358
The Nuclear Hormone Receptor PPARγ as a Therapeutic Target in Major Diseases
Published 2010-01-01“…The expression of PPARγ in lymphoid organs and its modulation of macrophage inflammatory responses, lymphocyte proliferation, cytokine production, and apoptosis underscore its immune regulating functions. …”
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13359
IL-38 Alleviates Inflammation in Sepsis in Mice by Inhibiting Macrophage Apoptosis and Activation of the NLRP3 Inflammasome
Published 2021-01-01“…Interleukin- (IL-) 38 is an emerging cytokine with multiple functions involved in infection and immunity. However, the potential role of IL-38 in the host immune response during sepsis remains elusive. …”
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13360
Myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment and their targeting in cancer therapy
Published 2025-01-01“…Myeloid-derived suppressor cells (MDSCs), due to their potent immunosuppressive capabilities, emerged as major negative regulators within the TME, facilitating tumor immune evasion by modulating various immune cells. In addition to their immunosuppressive functions, MDSCs also promote tumor growth and metastasis through non-immunological mechanisms, such as angiogenesis and the formation of pre-metastatic niches. …”
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