UV-C and Nanomaterial-Based Approaches for Sulfite-Free Wine Preservation: Effects on Polyphenol Profile and Microbiological Quality by Kamila Pachnowska, Jolanta Kochel-Karakulska, Adrian Augustyniak, Valentina Obradović, Ireneusz Ochmian, Sabina Lachowicz-Wiśniewska, Ireneusz Kapusta, Klaudia Maślana, Ewa Mijowska, Krzysztof Cendrowski

“…Therefore, this study aimed to test and implement iron oxide–silica core–shell nanomaterial functionalized with TiO₂ in UV-C treatment of white and red wines. …”
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Exploring lactylation and cancer biology: insights from pathogenesis to clinical applications by Zixuan Gou, Qianchuang Sun, Jiannan Li

“…As a byproduct of glycolysis, lactate functions as a signaling molecule, a substrate for energy metabolism, and a regulator of the tumor microenvironment (TME). …”
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Atomically engineering interlayer symmetry operations of two-dimensional crystals by Ziyi Han, Shengqiang Wu, Chun Huang, Fengyuan Xuan, Xiaocang Han, Yinfeng Long, Qing Zhang, Junxian Li, Yuan Meng, Lin Wang, Jiahuan Zhou, Wenping Hu, Jingsi Qiao, Dechao Geng, Xiaoxu Zhao

“…Abstract Crystal symmetry, which governs the local atomic coordination and bonding environment, is one of the paramount constituents that intrinsically dictate materials’ functionalities. However, engineering crystal symmetry is not straightforward due to the isotropically strong covalent/ionic bonds in crystals. …”
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Modeling the regulatory network of histone acetylation in Saccharomyces cerevisiae by Hung Pham, Roberto Ferrari, Shawn J Cokus, Siavash K Kurdistani, Matteo Pellegrini

“…We have utilized a linear regression of optimized sigmoidal functions to correlate transcription factor binding patterns to the acetylation profiles of 11 lysines in the four core histones measured at all S. cerevisiae promoters. …”
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Solely Light‐Induced Integrate‐and‐Fire 1T‐Neuron Operation and Implementation of the McGurk Effect by Jaehee Lee, Jung Wook Lim, Chohyeon Park

“…Therefore, neuromorphic systems designed to emulate the functionalities of the human brain have emerged as a potential solution to address this issue. …”
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Exogenous Control of the Expression of Group I CD1 Molecules Competent for Presentation of Microbial Nonpeptide Antigens to Human T Lymphocytes by Angelo Aquino, Grazia Graziani, Ornella Franzese, Salvatore P. Prete, Enzo Bonmassar, Laura Bonmassar, Stefania D'Atri

“…This scenario prompted us to perform a detailed analysis of the literature concerning the effect of external agents on Group I CD1 expression in order to obtain valuable information on the possible strategies to be adopted for driving properly CD1-dependent immune functions in human pathology and in particular, in human tuberculosis.…”
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An Ultra‐Fast Rolling Double‐Helical Robot Driven by Constant Humidity by Chuhan Xu, Jiayao Ma, Lei Fu, Xinmeng Liu, Lei Zhang, Yan Chen

“…This work is envisaged, and more generally the structural design and theoretical modeling principle, will open a new avenue for the development of advanced soft robotics with diverse functionalities.…”
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Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review by Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu

“…It is hoped that the insights provided in this review will be a valuable reference for developing nanocarriers with biosafety and precise functions as next‐generation therapies for CVDs.…”
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Long noncoding RNAs in acute myeloid leukemia: biomarkers, prognostic indicators, and treatment potential by Maryam Farajzadeh, Mehrdad Fathi, Pooya Jalali, Armin Mahmoudsalehi Kheshti, Shahla Khodayari, Mohammad Hojjat-Farsangi, Farhad Jadidi

“…Abstract Long noncoding RNAs (lncRNAs) have been recognized as significant modulators of gene expression and are essential for various biological functions, even though they don’t appear to have the ability to encode proteins. …”
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Leprosy patients: neurotrophic factors and axonal markers in skin lesions by Letícia Baccaro Michellin, Jaison Antonio Barreto, Lúcia Helena Soares Camargo Marciano, Flavio Alves Lara, Maria Esther Salles Nogueira, Vânia Nieto Brito de Souza, Maria Renata Sales Nogueira Costa

“…Neurotrophins are growth factors with crucial roles in neural pathophysiology. These mediators functionally modulate nociceptive fibers, and changes in neurotrophins expression have been correlated with early loss of nociception in leprosy. …”
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WTAP participates in the DNA damage response via an m6A-FOXM1-dependent manner in hepatocellular carcinoma by Nan Huang, Zhixuan Bian, Chang Xu, Yue Zhang, Li Liu, Zhongqi Cui, Shasha Zhao, Qiangyuan Fan, Shaobo Xue, Yan Chen, Qiuhui Pan, Fenyong Sun

“…Altogether, our findings demonstrate that WTAP is the dominant m6A -related modulator upon DNA damage and functions by stabilizing FOXM1. …”
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Nanoparticles for Glioblastoma Treatment by Dorota Bartusik-Aebisher, Kacper Rogóż, David Aebisher

“…A wide variety of nanocarriers, including dendrimers, liposomes, metallic nanoparticles, carbon nanotubes, carbon dots, extracellular vesicles, and many more demonstrate the ability to cross the BBB, precisely deliver therapeutic agents, and enhance the effects of radiotherapy and immunotherapy. Surface functionalization, peptide modification, and cell membrane coating improve the targeting capabilities of nanostructures toward GBM cells and enable the exploitation of their photothermal, magnetic, and optical properties. …”
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Bifunctional Memristive Behavior of a Dual‐Layer Structure Depending on the Configuration of Charge Transport by Suji Ha, YoungJu Park, Chanjin Lim, Eunyeong Yang, Taegil Kim, Seon Joon Kim, Junwoo Park

“…Abstract This paper presents a method for integrating neuronal and synaptic functions within a thin dual‐layer featuring distinct dielectric strengths. …”
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MRG15 alternative splicing regulates CDK1 transcriptional activity in mouse cell senescence and myocardial regeneration by Yuan Zhang, Huayu Wang, Fang Li, Hui Dai, Ye Zhang

“…Our research elucidates the distinct functions of MRG15’s splice variants in aging. We find that MRG15L, contrary to the previously assumed MRG15S, accumulates with advancing age. …”
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An Inducible Expression System of the Calcium-Activated Potassium Channel 4 to Study the Differential Impact on Embryonic Stem Cells by Stefan Liebau, Michael Tischendorf, Daniel Ansorge, Leonhard Linta, Marianne Stockmann, Clair Weidgang, Michelina Iacovino, Tobias Boeckers, Götz von Wichert, Michael Kyba, Alexander Kleger

“…The family of calcium-activated potassium channels consists of four members with varying biological functions and conductances. Besides membrane potential modulation, SK channels have been found to be involved in cardiac pacemaker cell development from ES cells and morphological shaping of neural stem cells. …”
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A 40 Gb/s Chip-to-Chip Interconnect for 8-Socket Direct Connectivity Using Integrated Photonics by Stelios Pitris, Miltiadis Moralis-Pegios, Theonitsa Alexoudi, Joris Lambrecht, Xin Yin, Johan Bauwelinck, Yoojin Ban, Peter De Heyn, Marianna Pantouvaki, Joris Van Campenhout, Ronald Broeke, Nikos Pleros

“…We present an O-band any-to-any chip-to-chip (C2C) interconnection at 40 Gb/s suitable for up to 8-socket direct connectivity in multi-socket server boards, utilizing integrated low-energy photonics for the transceiver and routing functions. The C2C interconnect exploits an Si-based ring modulator as its transmitter and a co-packaged photodiode/transimpedance amplifier enabled receiver interconnected over an 8 × 8 Si-based arrayed waveguide grating router, allowing for a single-hop flat-topology interconnection between eight nodes. …”
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A Strategy for Enhanced Post-FRT Active Power Recovery in Expandable Point-to-Point VSC-HVdc Links by Arcadio Perilla, Jose Luis Rueda Torres

“…This paper proposes a non-linear DC power modulation strategy for expandable point-to-point (PtP) high-voltage DC (HVDC) systems. …”
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Structural ubiquitin contributes to K48 linkage specificity of the HECT ligase Tom1 by Katrina Warner, Moritz Hunkeler, Kheewoong Baek, Anna Schmoker, Shourya S. Roy Burman, Daan Overwijn, Cyrus Jin, Katherine A. Donovan, Eric S. Fischer

“…Tom1 is one of five HECT ubiquitin E3 ligases in budding yeast S. cerevisiae and is prototypical for a ligase with pleiotropic functions such as ubiquitin chain amplification, orphan quality control, and DNA damage response. …”
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Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline by Jeremy M Shea, Saul A Villeda

“…Single-cell RNA-Seq and pseudotime analysis revealed age-related transcriptional heterogeneity in hippocampal microglia and identified intermediate states of microglial aging that also emerge following heterochronic parabiosis. We tested the functionality of intermediate stress response states via TGFβ1 and translational states using pharmacological approaches in vitro to reveal their modulation of the progression to an activated state. …”
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From neglect to necessity: the role of innate immunity in cutaneous squamous cell carcinoma therapy by Yong He, Ting Tian, Yuancheng Li, Yong Zeng, Yong Zeng, Yong Zeng, Xiaoke Wang, Leqi Qian, Tian Tian, Mingjun Jiang, Liming Li, Liming Li

“…Therefore, we focused on frequently neglected functions of innate immune cells. Emerging evidence indicates that innate immune cells exhibit considerable heterogeneity and plasticity, fundamentally contributing to tumor initiation and development. …”
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