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13241
Uncovering bifurcation behaviors of biochemical reaction systems from network topology
Published 2025-07-01“…Abstract The regulation of biological functions is achieved through the modulation of biochemical reaction network dynamics. …”
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13242
Fetuin-A – Alpha2-Heremans-Schmid Glycoprotein: From Structure to a Novel Marker of Chronic Diseases Part 2. Fetuin-A – A Marker of Insulin Resistance and Related Chronic Diseases...
Published 2018-06-01“…Fetuin-A is a secretory liver glycoprotein with multiple physiological functions such as regulation of insulin resistance, tissue calcification, bone metabolism, cellular proteolytic activity, and self-proliferative signaling.Fetuin-A is a unique molecule which binds to the insulin receptor, modulating its sensitivity, and transducing “the physiological conditions” (serum levels of the metabolites like glucose, free fatty acids, inflammatory signals) from outside into inside the cells. …”
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13243
The quest for democratic bliss: Which dimensions hold the key?
Published 2025-01-01“…It is argued that the evaluation of democracy and satisfaction with it are pivotal for ensuring its functioning and sustainability. When asked about the importance of specific indicators of democracy, such as free and fair elections, equality before the courts, and freedom of the press, most respondents assign a high and comparable level of importance to each. …”
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13244
Decoding biomolecular condensate dynamics: an energy landscape approach.
Published 2025-02-01“…Understanding how the molecular sequence grammar of LCDs governs condensate dynamics is essential for uncovering their biological functions and the evolutionary forces that shape these sequences. …”
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13245
Growth cone MKK7 mRNA targeting regulates MAP1b-dependent microtubule bundling to control neurite elongation.
Published 2012-01-01“…At the same time, this uncouples activated JNK from its functions relevant to nuclear translocation and transcriptional activation.…”
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13246
Circadian Regulation of Hippocampal-Dependent Memory: Circuits, Synapses, and Molecular Mechanisms
Published 2018-01-01“…While the suprachiasmatic nucleus (SCN) of the hypothalamus functions as the master mammalian pacemaker, recent evidence suggests that forebrain regions, including the hippocampus, exhibit oscillatory capacity. …”
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13247
Biosynthetic Machinery to Abiotic Stress-Driven Emission: Decoding Multilayer Regulation of Volatile Terpenoids in Plants
Published 2025-05-01“…This review synthesizes current knowledge of VT biosynthesis and emission under abiotic stress, highlights their antioxidant functions and regulatory architecture, and underscores their protective roles in redox homeostasis and stress signal transduction. …”
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13248
Provision of essential resources as a persistence strategy in food webs
Published 2023-09-01“…Pairwise interactions in food webs, including those between predator and prey are often modulated by a third species. Such higher-order interactions are important structural components of natural food webs that can increase the stability of communities against perturbations and ensure continued ecosystem functioning. …”
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13249
Design of a SMS Based Voting System.
Published 2023“…It was a well written code using the Arduino IDE was simulated, measured the output voltage, current and the output wave form displayed using the oscilloscope. Lastly a well-functioning system was obtained.…”
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13250
Transcriptome sequencing and Mendelian randomization analysis identified biomarkers related to neutrophil extracellular traps in diabetic retinopathy
Published 2024-10-01“…Additional analysis, including nomogram construction, gene set enrichment analysis, drug prediction and molecular docking, were performed to investigate the functions and molecular mechanisms of the key genes. …”
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13251
Wetland restoration suppresses microbial carbon metabolism by altering keystone species interactions
Published 2025-04-01“…Soil bacteria play a pivotal role in regulating multifaceted functions of terrestrial ecosystems. Unraveling the succession of bacterial communities and the feedback mechanism on soil organic carbon (SOC) dynamics help embed the ecology of microbiome into C cycling model. …”
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13252
Cell-targeted PD-1 agonists are potent NK-cell inhibitors
Published 2025-08-01“…Of note, NK cells can upregulate PD-1 expression upon activation and their effector functions can be modulated by the PD-1 signalling pathway.MethodsWe have generated a novel bispecific inhibitory molecule, comprised of a targeting domain highly specific for a pre-pro-insulin peptide presented by the HLA-A*02 molecules on the cell surface of pancreatic β-cells and a PD-1 agonist effector domain. …”
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13253
Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study
Published 2025-02-01“…Consumption of BRBs improved cognitive functions (p < 0.00001), compared to the placebo group (p > 0.05). …”
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13254
Comprehensive transcriptomic analysis integrating bulk and single-cell RNA-seq with machine learning to identify and validate mitochondrial unfolded protein response biomarkers in...
Published 2025-04-01“…Next, the mechanisms and functions related to the biomarkers were explored by enrichment analysis and immune infiltration. …”
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13255
Effect of altitude on the spatiotemporal signal characteristics of inversion face recognition
Published 2025-07-01“…Abstract High-altitude environments, can significantly impact cognitive functions, yet the neural mechanisms underlying altitude-induced changes in face recognition remain largely unexplored. …”
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13256
A hybrid encryption framework leveraging quantum and classical cryptography for secure transmission of medical images in IoT-based telemedicine networks
Published 2024-12-01“…After the confusion phase, a combination of affine transformations with non-linear functions, Discrete Cosine Transform (DCT) with complex modulation, Discrete Wavelet Transform (DWT) with random phase modulation, bilinear transformation, and nonlinear polynomial mapping are employed to create diffusion in the scrambled components. …”
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13257
Developing the data management component of an academic discipline program for an educational management information system
Published 2023-02-01“…An analysis of links between the ADP and key entities of the educational process is presented. The functionality of the self-developed ADP module for implementing at RTU MIREA is aimed at providing interconnection, transparency, and availability of links between academic discipline parameters and its sections.Conclusions. …”
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13258
Idiopathic epilepsy in dogs is associated with dysbiotic faecal microbiota
Published 2025-03-01“…Abstract Background The gut microbiota plays a crucial role in modulating various physiological and pathological processes through its metabolites, including short-chain fatty acids (SCFA), which impact immune system development, gastrointestinal health, and brain functions via the gut-brain axis. …”
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13259
Female Anopheles Mosquito Gut Microbiota: Description and Impact on Transmission of Plasmodium Parasite
Published 2025-06-01“…Key focus areas include the structure and diversity of Anopheles gut microbiota, their immunomodulatory functions, interactions with P. falciparum, and potential applications in paratransgenesis and biological vector control. …”
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13260
Improved YOLOv8 Algorithm was Used to Segment Cucumber Seedlings Under Complex Artificial Light Conditions
Published 2025-01-01“…With the widespread application and rapid proliferation of agricultural solutions in plant factories, “intelligent environmental control technology” has become an important research topic as one of the core functions of plant factories. Accurately obtaining the growth status of plants is the core of intelligent control technology and has been capturing more and more researchers’ attention. …”
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