-
13141
Progress in research on nutrition, neuroinflammation and dopaminergic alterations in Tic disorders
Published 2025-05-01“…Nutritional factors influence the dopaminergic system's functionality by affecting neurotransmitter synthesis and metabolism, modulating gut microbiota and contributing to neuroinflammation. …”
Get full text
Article -
13142
A lightweight and optimized deep learning model for detecting banana bunches and stalks in autonomous harvesting vehicles
Published 2025-08-01“…Developing algorithms to identify fruit cutting locations is important for the functionality of harvesting robots. However, existing studies often rely on multi-stage detection processes. …”
Get full text
Article -
13143
Proline and ROS: A Unified Mechanism in Plant Development and Stress Response?
Published 2024-12-01“…However, the molecular mechanisms and the relative importance of these additional functions of proline remain under study. It is well documented that both stress responses and developmental processes are associated with proline accumulation. …”
Get full text
Article -
13144
Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism
Published 2025-08-01“…Single-cell RNA sequencing (scRNA-seq) identified key cell types and their functions. Biomarkers were validated via reverse transcription quantitative polymerase chain reaction (RT-qPCR). …”
Get full text
Article -
13145
Protein Engineering Strategies to Expand CRISPR-Cas9 Applications
Published 2018-01-01“…Here, recent protein-engineering approaches for expanding the versatility of the Streptococcus pyogenes Cas9 (SpCas9) is reviewed, with an emphasis on studies that improve or develop novel protein functions through domain fusion or splitting, rational design, and directed evolution.…”
Get full text
Article -
13146
Transcriptomic and lipidomic analysis of aging-associated inflammatory signature in mouse liver
Published 2025-05-01“…The gut microbiota crosstalks with the host by providing lipid metabolites and modulating metabolic functions. However, the precise mechanism by which the gut microbiota regulates aging is unknown. …”
Get full text
Article -
13147
TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos.
Published 2013-01-01“…This pathway directly regulates several target genes that mediate its downstream functions, however very few microRNAs (miRNAs) have been identified as targets. miRNAs are modulators of gene expression with essential roles in development and a clear association with diseases including cancer. …”
Get full text
Article -
13148
Expression of genes belonging to the interacting TLR cascades, NADPH-oxidase and mitochondrial oxidative phosphorylation in septic patients.
Published 2017-01-01“…Interferon signaling, marked by changes in JAK-STAT modulation, had prominent changes in both survivors and non-survivors, whereas the redox imbalance (iNOS signaling, oxidative phosphorylation and superoxide radical degradation) affecting mitochondrial functions was prominent in non-surviving patients.…”
Get full text
Article -
13149
Remote Sensing Extraction of Damaged Buildings in the Shigatse Earthquake, 2025: A Hybrid YOLO-E and SAM2 Approach
Published 2025-07-01“…In this hybrid approach, YOLO-E functions as the preliminary segmentation module for initial segmentation. …”
Get full text
Article -
13150
Mitochondrial damage-associated molecular patterns: Neuroimmunomodulators in central nervous system pathophysiology
Published 2026-04-01“…Microglia are the resident immune cells of the central nervous system, while astrocytes are the main support cells for neuronal functions but can also participate in neuroimmune responses. …”
Get full text
Article -
13151
Features of therapy of patients with chronic cerebral ischemia and neurodegenerative diseases during the COVID-19 pandemic
Published 2022-03-01“…Emphasis is placed on the correction of GABA-ergic transmission, which is responsible for a number of functions of the central nervous system (cognition, executive functions, modulation of motor activity), the violation of which is shown both in the acute period of COVID-19 and after its termination in the framework of the postcovid syndrome.…”
Get full text
Article -
13152
Neonatal testosterone exposure alleviates female-specific severity of formalin-induced inflammatory pain in mice
Published 2025-07-01“…The latter effects of gonadal hormones, called organizational effects, are critical for establishing sex-specific reproductive functions and transforming them postnatally. However, it remains unclear whether the organizational effects determine sex-specific pain severity in adulthood. …”
Get full text
Article -
13153
The differential role of aryl hydrocarbon receptor in skin cancers induced by environmental carcinogens, including ultraviolet irradiation, arsenic exposure, and HPV infection
Published 2025-01-01“…The skin functions as the primary barrier organ in humans, safeguarding against environmental insults and challenges. …”
Get full text
Article -
13154
The Role of Exogenously Applied Polyamines to Improve Heat Tolerance in Tomatoes: A Review
Published 2025-05-01“…Among various abiotic stresses, heat stress (HS) can severely impair tomato growth, reproduction, and physiological functions. Polyamines (PAs), such as spermidine (Spd), putrescine (Put), and spermine (Spm), are natural compounds that play vital roles in plant stress tolerance by modulating growth and physiological responses. …”
Get full text
Article -
13155
A Lightweight AI-Based Approach for Drone Jamming Detection
Published 2025-01-01“…However, drone networks are particularly vulnerable to jamming attacks, a type of availability attack that can disrupt network operation and hinder drone functionality. In this paper, we propose a low complexity unsupervised machine learning approach for the detection of constant and periodic jamming attacks, using the Isolation Forest algorithm. …”
Get full text
Article -
13156
Harnessing Ferrocene for Hydrogen and Carbon Dioxide Transformations: From Electrocatalysis to Capture
Published 2025-07-01“…This review critically examines recent advances in Fc-based systems for hydrogen evolution and carbon dioxide (CO<sub>2</sub>) conversion, encompassing electrochemical, photochemical, and thermochemical strategies. Fc serves diverse functions: it operates as a reversible redox mediator, an electron reservoir, a ligand framework, and a structural modulator. …”
Get full text
Article -
13157
In Silico Conotoxin Studies: Progress and Prospects
Published 2024-12-01“…Cone snails of the genus <i>Conus</i> have evolved to produce structurally distinct and functionally diverse venom peptides for defensive and predatory purposes. …”
Get full text
Article -
13158
Role of S-palmitoylation in digestive system diseases
Published 2025-07-01“…By elucidating the regulatory functions of palmitoylation under these conditions, this review aimed to identify new strategies for the diagnosis and treatment of digestive system disorders.…”
Get full text
Article -
13159
The Role of Uncoupling Proteins in Diabetes Mellitus
Published 2013-01-01“…Uncoupling proteins (UCPs) are anion carriers expressed in the mitochondrial inner membrane that uncouple oxygen consumption by the respiratory chain from ATP synthesis. The physiological functions of UCPs have long been debated since the new UCPs (UCP2 to 5) were discovered, and the role of UCPs in the pathogeneses of diabetes mellitus is one of the hottest topics. …”
Get full text
Article -
13160
EEMD Energy Spectrum Decoupling: An Efficient Hilbert–Huang Fusion Approach for Intelligent Bearing Fault Diagnosis
Published 2025-06-01“…Subsequently, the demodulated envelope signal is decomposed by EEMD to extract Intrinsic Mode Functions (IMFs), where each IMF component is calculated layer by layer using a normalization method based on the EEMD decomposition sequence. …”
Get full text
Article