Targeting mitochondrial transfer: a new horizon in cardiovascular disease treatment by Baile Zuo, Xiaoyan Li, Dawei Xu, Liping Zhao, Yang Yang, Yi Luan, Bi Zhang

“…This review offers a comprehensive examination of the relevance of mitochondrial transfer to cardiovascular health and disease, emphasizing the critical functions of mitochondria in energy metabolism and signal transduction within the cardiovascular system. …”
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Investigating Advanced Approaches Based on Iso-Absorptivity Coefficient in Unresolved Spectral Signals of Binary Mixtures by Hayam M. Lotfy, Sarah S. Saleh

“…Several spectrophotometric approaches utilize different functions of the iso-absorptivity coefficient in zero-order absorption signals and its manipulated spectra. …”
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The central signaling pathways related to metabolism-regulating hormones of the gut-brain axis: a review by Jiyuan Liu, Changqing Jing, Ying Guo, Zhou Shang, Baolin Zhang, Xinxiu Zhou, Jizhun Zhang, Guodong Lian, Feng Tian, Leping Li, Yuezhi Chen

“…The present research systematically evaluates the impact of bariatric surgery on appetite modulation and certain metabolic functions through key signaling pathways, including GLP-1R, GHS-R1a, and FXR/TGR5.…”
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Biosynthesis and bioactivity of anti-inflammatory triterpenoids in Calendula officinalis by D. Golubova, M. Salmon, H. Su, C. Tansley, GG Kaithakottil, G. Linsmith, C. Schudoma, D. Swarbreck, MA O’Connell, NJ Patron

“…Further, we functionally characterise cytochrome P450s and acyltransferases responsible for downstream modifications. …”
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Revealing the impact of Pseudomonas aeruginosa quorum sensing molecule 2’-aminoacetophenone on the human bronchial-airway epithelium and pulmonary endothelium using a human airway-... by Shifu Aggarwal, Shifu Aggarwal, Arijit Chakraborty, Arijit Chakraborty, Arijit Chakraborty, Vijay K. Singh, Stephen Lory, Katia Karalis, Laurence G. Rahme, Laurence G. Rahme, Laurence G. Rahme

“…BackgroundPseudomonas aeruginosa (PA) causes severe respiratory infections utilizing multiple virulence functions. Previous findings on the PA secreted quorum sensing (QS)-regulated small molecule, 2’-aminoacetophenone (2-AA), revealed its impact on immune and metabolic functions, favouring a long-term presence of PA in the host. …”
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Assessment of health-related quality of life of children with idiopathic nephrotic syndrome and their caregivers in China by Xia Wang, Danny Junyi Tan, Lejing Guan, Yifei Shao, Jingjing Wang, Chunyue Feng, Haidong Fu, Huijun Shen, Xiujuan Zhu, Abdul Rafay, Jianhua Mao, Guannan Bai

“…Results HRQoL of Children with INS declines with increasing age, and children aged 5-18 had lower scores in physical functioning, emotional functioning, school functioning, psychosocial health summary score, and total PedsQL™ 4.0 GCM score compared to healthy children. …”
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Fecal microbiota transplantation alters the proteomic landscape of inflammation in HIV: identifying bacterial drivers by Claudio Díaz-García, Elena Moreno, Alba Talavera-Rodríguez, Lucía Martín-Fernández, Sara González-Bodí, Laura Martín-Pedraza, José A. Pérez-Molina, Fernando Dronda, María José Gosalbes, Laura Luna, María Jesús Vivancos, Jaime Huerta-Cepas, Santiago Moreno, Sergio Serrano-Villar

“…Concurrently, we characterized shifts in the gut microbiota composition and annotated functions through shotgun metagenomics. We fitted generalized additive models to evaluate the dynamics of protein expression. …”
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Long Non-Coding RNA lncTAF15:1-1 Promotes CCL5 Secretion and Cell Migration of Monocyte-Derived Dendritic Cells via PI3K/AKT/mTOR Pathway in Systemic Lupus Erythematosus by Xiang M, Sun Z, Ge Y, Zhang Z, Zheng C, Gao Z, Wang J, Xu J, Liang J, Wang Y

“…Hence, this study tried to reveal the underlying roles of one lncRNA, lncTAF15:1– 1, in modulating DC functions and its involvement with CCL5 secretion in SLE pathogenesis.Methods: The expression levels of lncTAF15:1– 1 were measured using qPCR in cultivated monocyte-derived dendritic cells (moDCs). …”
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Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV by Stephanie M. Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A. Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C. M. Schlachetzki, Howard S. Fox, Peter J. Gaskill

“…Abstract The catecholamine neurotransmitter dopamine is classically known for regulation of central nervous system (CNS) functions such as reward, movement, and cognition. …”
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Prototype Development and Experimental Validation for Wind Energy Harvesting from HVAC System for A Charging Station by Siti Marwangi Mohamad Maharum, Muhammad Aliff Azim Hamzah, Muhammad Ridzwan Ahmad Yusri, Izanoordina Ahmad

“…This connection would efficiently convert wind energy into electrical power. An energy storage module is also incorporated to ensure uninterrupted functionality for the developed charging station prototype. …”
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Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells. by James Pritchett, Varinder S Athwal, Emma Harvey, Katherine Martin, Jessica Llewellyn, Philip Ireland, Alexander Nicolaides, Martin J Humphries, Nicoletta Bobola, Neil A Hanley, Karen Piper Hanley

“…<h4>Conclusion</h4>These data provide evidence for EPIM and SOX9 functioning by mutual negative feedback to regulate attributes of the quiescent or activated state of HSCs. …”
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DEVELOPMENT OF THE APPLICATION FOR THE INFORMATION SUPPORT OF LOGISTIC BUSINESS PROCESSES OF THE CONSTRUCTION SERVICES ON BUILDINGS INSULATION by Andrei Popov, Alina Yelizyeva, Sergey Gubka, Sergey Kryivulia

“…The following problems were solved: analysis of functionality the sites of the companies providing insulation services; formation of business process diagrams; database development; web application development for business processes informational support for buildings facades insulation. …”
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The Hydrodynamic Performance of a Vertical-Axis Hydro Turbine with an Airfoil Designed Based on the Outline of a Sailfish by Aiping Wu, Shiming Wang, Chenglin Ding

“…The centrifugal rotor component harnessed tidal current kinetic energy while the axial-flow rotor module captured wave-induced potential energy. Transient numerical simulations employing dynamic mesh techniques and user-defined functions within the Fluent environment were conducted to analyze rotor interactions. …”
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Identification of Biomarkers Associated with Heart Failure Caused by Idiopathic Dilated Cardiomyopathy Using WGCNA and Machine Learning Algorithms by Mengyi Sun, Linping Li

“…We then identified the differentially expressed genes (DEGs) and analyzed their functions and related pathways by using “Metascape”. …”
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Ethanolic Extract of Papaya (Carica papaya) Leaves Improves Blood Cholesterol Profiles and Bone Density in Ovariectomized Rats by Raisatun Nisa Sugiyanto, Rahmi Khamsita, Ratna Asmah Susidarti

“…Bone loss and disturbance in the blood cholesterol profiles modulation are two effects caused by menopauses syndromes. …”
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Rho-GTPases subfamily: cellular defectors orchestrating viral infection by Beibei Zhang, Shuli Li, Juntao Ding, Jingxia Guo, Zhenghai Ma, Hong Duan

“…Furthermore, Rho-GTPases modulate immune responses, often suppressing antiviral defenses to favor viral replication. …”
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Systemic inflammation as a central player in the initiation and development of Alzheimer’s disease by Irem Bayraktaroglu, Natalia Ortí-Casañ, Debby Van Dam, Peter P. De Deyn, Ulrich L. M. Eisel

“…Furthermore, we highlight key immune signaling pathways involved in both central and peripheral immune responses, such as the NLRP3 inflammasome and TREM2, which represent promising therapeutic targets for modulating inflammation while preserving protective immune functions. …”
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Mathematical model for predicting the performance of photovoltaic system with delayed solar irradiance by Siti Nurashiken Md Sabudin, Norazaliza Mohd Jamil

“…The output current and power for the solar photovoltaic panel were treated as time-dependent functions. As the solar irradiance increases, the output current and power of the solar panel will increase. …”
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Novel Delivery of Cyclic-Diguanylate Monophosphate Utilizing Amyloid Depots by Maytham Ismail, Benjamin Beluzo, Sergei Chuikov, Venkateshwar G. Keshamouni, Mathumai Kanapathipillai

“…Both RIP3 and lysozyme proteins have intrinsic physiological functions. This is the first time intrinsic peptides/protein-based amyloids have been explored for c-di-GMP delivery. …”
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A Comprehensive Review of the Brain–Gut Microbiota System in Traumatic Brain Injury: Mechanisms, Outcomes, and Emerging Interventions by Venencia Albert, Shweta Kedia, Arulselvi Subramanian

“…The gut microbiome, a diverse community of commensal microorganisms, is integral to gut physiology, performing key functions such as metabolic regulation, maintaining the intestinal barrier, and modulating immune responses. …”
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