The role of tRNA-Derived small RNAs (tsRNAs) in pancreatic cancer and acute pancreatitis by Yan Pan, Xiaowei Ying, Xueting Zhang, Hongting Jiang, Junjie Yan, Shiwei Duan

“…tRNA-derived small RNAs (tsRNAs), encompassing tRNA fragments (tRFs) and tRNA-derived stress-induced RNAs (tiRNAs), represent a category of non-coding small RNAs (sncRNAs) that are increasingly recognized for their diverse biological functions. These functions include gene silencing, ribosome biogenesis, retrotransposition, and epigenetics. tsRNAs have been identified as key players in the progression of various tumors, yet their specific roles in pancreatic cancer (PC) and acute pancreatitis (AP) remain largely unexplored. …”
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Astrocytes carrying LRRK2 G2019S exhibit increased levels of clusterin chaperone via miR-22-5p and reduced ability to take up α-synuclein fibrils by Alice Filippini, Giulia Carini, Alessandro Barbon, Massimo Gennarelli, Isabella Russo

“…Leucine-rich repeat kinase 2 (LRRK2), a gene linked to genetic and familial PD, has been reported to affect astrocytic-related functions, including the ingestion of alpha-synuclein (α-syn) aggregates. …”
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Transformer-Based Person Detection in Paired RGB-T Aerial Images With VTSaR Dataset by Xiangqing Zhang, Yan Feng, Nan Wang, Guohua Lu, Shaohui Mei

“…VTSaRNet integrates the instance segmentation for copy–paste mechanism (ISCP) using a Union Transformer Network that functions in both Visible (V) and Thermal (T) bimodalities. …”
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Brake rigging dynamic simulation under braking on a track section with irregularities (the case of a passenger car) by I. A. Yaitskov, V. V. Kosarevskii

“…In addition, under the superposition of the bogie-frame pitching and bouncing oscillations, when moving along an uneven track, the rigging block can move up and down the wheel-working surface within a range of up to 50 mm. The simulation functionality of the dynamic processes of the brake system of a passenger car was expanded in the “UM-Loko” software package.Discussion and Conclusions. …”
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Identification and Experimental Validation of Biomarkers Related to MiR-125a-5p in Chronic Obstructive Pulmonary Disease by Jing X, Li Y

“…Enrichment analysis showed their roles in various cellular functions. In addition, significant associations were identified between 9 distinct cells and biomarkers. …”
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In Silico Evaluation of Terpene Interactions with Inflammatory Enzymes: A Blind Docking Study Targeting Arachidonic Acid Metabolism by Djeni Cherneva, Kaloyan Mihalev, Ivelin Iliev, Nadya Agova, Galina Yaneva, Tsonka Dimitrova, Svetlana Georgieva

“…The focus is on compounds with potential to modulate arachidonic acid metabolism. In this context, β-pinene engages the catalytic site of PLA₂, linalool forms multiple contacts within key regions of 5-LOX, and menthol, α-pinene, and β-pinene align with functionally important regions in both COX isoforms. …”
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Illumination-adaptative granularity progressive multimodal image fusion method by Chuanyun WANG, Dongdong SUN, Mingqi ZHOU, Tian WANG, Qian GAO, Zhaokui LI

“…Homogeneous and heterogeneous loss functions are constructed based on different environmental conditions, enabling adaptive learning. …”
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Development and use of a fully automatic clinical intelligent milk dispenser (一种全自动临床智能配奶机的研制与使用) by ZHANG Rongbang (张榕邦), OUYANG Li (欧阳丽), JIN Mu (金募), LIU Lingzhi (刘羚芷), LIN Yan (林妍), ZHANG Zhiyuan (张秩源)

“…Among them, the control panel includes a main control circuit board, a music sound and light module, a temperature display module, a milk/flush module, a temperature control module, and a wireless receiving module. …”
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Xylooligosaccharide Production From Lignocellulosic Biomass and Their Health Benefits as Prebiotics by Kajal Kumari, Sushil Nagar, Sakshi Goyal, Sonu Maan, Vishal Chugh, Vinod Kumar, Neeraj Kharor

“…Importance of XOS being valuable food ingredient is increasing as they perform a variety of functions, including reduction in cholesterol levels, gastrointestinal health maintenance, anticancer and antioxidant properties, and modulation of immune system. …”
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Impact of Immunosenescence on Vaccine Immune Responses and Countermeasures by Li Chen, Chengwei Shao, Jingxin Li, Fengcai Zhu

“…As individuals grow older, their physiological functions gradually decline, including compromised immune responses, leading to immunosenescence. …”
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Metallothionein-3-mediated intracellular zinc mediates antioxidant and anti-inflammatory responses in the complete Freund’s adjuvant-induced inflammatory pain mouse model by Ngoc Buu Tran, Sook-Jeong Lee

“…This study highlights the critical role of MT3 in coordinating the intracellular interaction with Zn2+, which is vital for the immune systems’s protective functions. These interactions are fundamental for maintaining metal ion homeostasis and regulating the synthesis of various biomolecules in the body.…”
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The role of neutrophils in the pathogenesis of ischemic stroke by I. I. Dolgushin, Z. Z. Zaripova, M. I. Karpova

“…The review showed that the contribution of neutrophils to the pathogenesis of ischemic stroke is associated with implementation of their secretory, regulatory, and phagocytic functions, as well as with NETosis.Conclusion. It was shown that neutrophils are involved in the pathogenesis of ischemic stroke and modulate a response to treatment.…”
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IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPKα to attenuate hypercholesterolemia by Jiaqi Li, Mingchao Wang, Kai Qu, Yuyao Sun, Zequn Yin, Na Dong, Xin Sun, Yitong Xu, Liang Chen, Shuang Zhang, Xunde Xian, Suowen Xu, Likun Ma, Yajun Duan, Haibo Zhu

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Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells by Jetzabel Vidal-Vidal, David Brown-Brown, Nelson Quilaqueo-Millaqueo, Gaspar Peña-Münzenmayer, Carlos Spichiger, Claudia Quezada-Monrás, Flavio Salazar-Onfray, Julio C. Tapia, Ignacio Niechi

“…Treatment also decreased the expression of EMT and stemness markers CD44 and Vimentin. Functionally, rNEP reduced cell migration, invasion, and colony formation, while SM19712 affected migration and colony formation. …”
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MicroRNA‐378a‐3p contributes to ovarian cancer progression through downregulating PDIA4 by Yao Chanjiao, Chen Chunyan, Qiu Xiaoxin, Han Youjian

“…Furthermore, pcDNA3.1‐PDIA4 largely eliminated the functions of miR‐378a‐3p mimic on phosphorylation levels of AKT and PI3K. …”
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Fabrication of hydrogels with steep stiffness gradients for studying cell mechanical response. by Raimon Sunyer, Albert J Jin, Ralph Nossal, Dan L Sackett

“…The hydrogels can be covalently functionalized with uniform coatings of proteins that promote cell adhesion. …”
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Gut microbiota in liver diseases: initiation, development and therapy by Jian-Xiu Yu, Jun Wu, Xin Chen, Su-gang Zang, Xue-bin Li, Li-Pei Wu, Shi-hai Xuan

“…Research indicates that dysbiosis of the gut microbiota can disrupt the integrity of the intestinal barrier and interfere with the immune functions of the gut-liver axis, thereby mediating the progression of liver diseases. …”
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Deletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivo. by Manuel D Díaz-Muñoz, Sarah E Bell, Martin Turner

“…Here we have functionally characterised the importance of the AREs present within the Bcl2 3'UTR in order to maintain Bcl2 expression. …”
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MATLAB Simulation of UPQC for Power Quality Mitigation Using an Ant Colony Based Fuzzy Control Technique by N. Kumarasabapathy, P. S. Manoharan

“…To enable this, a systematic approach for creating the fuzzy membership functions is carried out by using an ant colony optimization technique for optimal fuzzy logic control. …”
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A New QIM-Based Watermarking Method Robust to Gain Attack by Yevhen Zolotavkin, Martti Juhola

“…The proposed method also exploits a new form of distribution of quantized samples where samples that interpret “0” and “1” have differently shaped probability density functions. Compared to well-known watermarking schemes, this provides an increase of capacity under noise attack and introduces a distinctive feature. …”
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