Bacillus vallismortis acts against ginseng root rot by modifying the composition and microecological functions of ginseng root endophytes by Yang Hu, Liu-yang Yang, Meng-yuan Lei, Yi-xin Yang, Zhuo Sun, Wan Wang, Zhong-ming Han, Lin Cheng, Ze-liang Lv, Mei Han, Li-min Yang

“…IntroductionThe endophytic microbiome serves a crucial function as a secondary line of defense against pathogen invasion in plants. …”
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Working memory related functional connectivity in adult ADHD and its amenability to training: A randomized controlled trial by Tuija Tolonen, Sami Leppämäki, Timo Roine, Kimmo Alho, Pekka Tani, Anniina Koski, Matti Laine, Juha Salmi

“…WM training did not modulate functional or structural connectivity compared with the active controls. …”
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Functional Profiling of <i>Enterococcus</i> and <i>Pediococcus</i> Strains: An In Vitro Study on Probiotic and Postbiotic Properties by Mircea-Cosmin Pristavu, Filofteia Camelia Diguță, Alexandru Constantin Aldea, Florentina Badea, Mihaela Dragoi Cudalbeanu, Alina Ortan, Florentina Matei

“…Probiotics and their postbiotic derivatives offer promising health benefits, including pathogen inhibition and immune modulation. These findings highlight several LAB strains with promising probiotic traits and postbiotic efficacy, supporting their potential use in functional foods and therapeutic applications.…”
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Curcumin Mitigates Gut Dysbiosis and Enhances Gut Barrier Function to Alleviate Metabolic Dysfunction in Obese, Aged Mice by Gopal Lamichhane, Femi Olawale, Jing Liu, Da-Yeon Lee, Su-Jeong Lee, Nathan Chaffin, Sanmi Alake, Edralin A. Lucas, Guolong Zhang, Josephine M. Egan, Yoo Kim

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Monochromatic Light Impacts the Growth Performance, Intestinal Morphology, Barrier Function, Antioxidant Status, and Microflora of Yangzhou Geese by Gang Luo, Yiyi Cheng, Yingqing Xu, Jie Liu, Wen Yang, Jiying Liu, Binbin Guo, Huanxi Zhu

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Shenmai injection revives cardiac function in rats with hypertensive heart failure: involvement of microbial-host co-metabolism by Lin Li, Senjie Zhong, Jiahao Ye, Siyuan Hu, Xiajun Xiong, Guangyu Chen, Zhixi Hu

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Genomic and Functional Characterization of Multidrug-Resistant <i>E. coli</i>: Insights into Resistome, Virulome, and Signaling Systems by Vijaya Bharathi Srinivasan, Naveenraj Rajasekar, Karthikeyan Krishnan, Mahesh Kumar, Chankit Giri, Balvinder Singh, Govindan Rajamohan

“…These findings lay the groundwork for future functional studies aimed at targeting stress-response pathways as novel intervention strategies against antimicrobial resistance.…”
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Roughage Sources During Late Gestation and Lactation Alter Metabolism, Immune Function and Rumen Microbiota in Ewes and Their Offsprings by Haidong Du, Kenan Li, Wenliang Guo, Meila Na, Jing Zhang, Renhua Na

“…However, ewes fed AH exhibited significant improvements in immune function and overall health for both them and their lambs.…”
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Microtubule-actin crosslinking factor 1 (Macf1) domain function in Balbiani body dissociation and nuclear positioning. by Matias Escobar-Aguirre, Hong Zhang, Allison Jamieson-Lucy, Mary C Mullins

“…To our knowledge, this is also the first study to use genome editing to unravel the module-dependent function of a cytoskeletal linker.…”
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Integrated multiomics analysis identifies PHLDA1+ fibroblasts as prognostic biomarkers and mediators of biological functions in pancreatic cancer by Rui Wang, Rui Wang, Guan-Hua Qin, Guan-Hua Qin, Yifei Jiang, Fu-Xiang Chen, Fu-Xiang Chen, Zi-Han Wang, Zi-Han Wang, Lin-Ling Ju, Lin Chen, Da Fu, En-Yu Liu, Su-Qing Zhang, Wei-Hua Cai

“…However, the prognostic and functional contributions of distinct CAF subtypes remain inadequately understood. …”
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Effects of Verbena and Polygonum cuspidatum on growth performance, immune functions, cecal microbiota, and brain metabolites in Sansui ducks by Yongcai Zhu, Qiaoqun Wu, Linli Luo, Shenglin Yang

“…Supplementation with Verbena officinalis and Polygonum cuspidatum enhanced growth performance, immunity, and brain neurochemical profiles, potentially through gut microbiota modulation. These herbs show promise as functional feed additives in duck production.…”
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Complex interplay between gene deletions and the environment uncovers cellular roles for genes of unknown function in Escherichia coli by Kaat Sondervorst, Kristina Nesporova, Matthew Herdman, Bart Steemans, Joëlle Rosseels, Sander K. Govers

“…One major confounding factor is the environment and its ability to modulate phenotypic outcomes. Another fact is that a large fraction of protein-coding genes in bacterial genomes remain uncharacterized and have no known function. …”
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Multi-omics dissection of CPNE1 reveals its prognostic value and immune-regulatory function in liver cancer by Liu Liu, He Hong, Weiwei Zhang, Xiang Li, Yuan Yao, Zhengjun Zhang, Guangyao Li

“…Using a series of bioinformatics analyses, including expression, correlation, and survival analyses, we predicted the upstream miRNAs and lncRNAs of CPNE1 and explored its regulatory network through the competitive endogenous RNA (ceRNA) mechanism. Subsequently, functional enrichment analysis was conducted to explore the related functions and signaling pathways of the target genes. …”
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Green tea silver nanoparticles improve physiological motor and cognitive function in BALB/c mice during inflammation by Herbert Izo, Ninsiima, Ejike, Daniel Eze, Kenneth, Ssekatawa, Halima, Nalugo, Caroline, Asekenye, David, Onanyang, Edson Ireeta, Munanura, Moses, Ariong, Kevin, Matama, Gerald, Zirintunda, Ngala Elvis, Mbiydzenyuy, Fred, Ssempijja, Adam Moyosore, Afodun, Ibe Michael, Usman, Oscar Hilary, Asiimwe, Julius, Tibyangye, Keneth Iceland, Kasozi

“…Here, synthesized green tea AgNPs registered anabsorbance band at 460 nm, phytochemicals due to presence of organic functional groups of O––C––O of oxycarbons, of C––C of a conjugate alkene, C––O of a stretching bond of a secondary alcohol. …”
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Combinatorial mutagenesis and fermentation optimization biotechnologies synergistically enhance monacolin K content in functional red yeast rice by Zhengyan Wu, Chan Zhang, Qing Liu, Song Zhang, Qi Yang, Jun Liu, Dong Lu, Xiang Zhou

“…IntroductionRed yeast rice (RYR) is produced through solid-state fermentation by Monascus genus. Its functional component, Monacolin K (MK), has the same structure as lovastatin and can effectively inhibit HMG-CoA reductase, thereby reducing serum cholesterol.MethodsA combinatorial mutagenesis strategy integrating atmospheric room-temperature plasma and heavy-ion radiation was employed to generate mutant strains. …”
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Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA‐Seq Analysis by Fengshuo Zhang, Quyangangmao Su, Zhanhong Gao, Zhenling Wu, Qiurong Ji, Tingli He, Kaina Zhu, Xuan Chen, Yu Zhang, Shengzhen Hou, Linsheng Gui

“…The results indicated that the 1:1 group significantly upregulated the expression of PTGS2, PLA2G12A and PLA2G4 genes, enhancing antioxidant enzyme activity, reducing free radical production and modulating systemic immune responses. COL16A1 and KCNK5 were highly expressed in the protein digestion and absorption pathway, maintaining the structural integrity and function of the rumen epithelium. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…Results Here, we show that enhancer mutation of MEF2C reduces own gene expression and consequently impairs mitochondrial function in motor neurons. MEF2C localizes and binds to the mitochondria DNA, and directly modulates mitochondria-encoded gene expression. …”
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It is not waste if it is therapy: cellular, secretory and functional properties of reamer–irrigator–aspirator (RIA)-derived autologous bone grafts by S. Häusner, A. Kolb, K. Übelmesser, S. Hölscher-Doht, M. C. Jordan, A. Jauković, F. Berberich-Siebelt, D. V. Spasovski, J. Groll, T. Blunk, M. Herrmann

“…Growth factor and cytokine contents were assessed through antibody arrays. Possible functional and immunomodulatory properties of RIA liquid were evaluated in functional in vitro assays. …”
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Evaluation of Curcuma xanthorrhiza Roxb. extract as a functional alternative to antibiotic growth promoters in broiler chicken nutrition by Arnold Parlindungan Sinurat, Tuti Haryati, Maijon Purba, Tiurma Pasaribu, Yan Irawan, Ryan Haryo Setyawan, Ferdy Saputra, Muhammad Ilyas, Nila Miraya, Sumiati Sumiati

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Monitoring of coordinates for modules of unrigged phased antenna array by A. V. Poltavskiy

“…Coherent method for realizing of the device for modules-units start monitoring of phased antenna array is suggested. …”
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