-
12921
Near‐Field Optical Nanopatterning of Graphene
Published 2025-08-01“…Importantly, nano‐ Fourier transform infrared spectroscopy reveals selective oxidative functionalization at the periphery of the nanopunch holes, highlighting a controlled surface modification of graphene. …”
Get full text
Article -
12922
Memory T Cell Subsets Expressing Tissue Homing Receptors and Chemokine Levels in Human Tegumentary Leishmaniasis
Published 2025-04-01“…Finally, we demonstrated the ability of <i>Leishmania</i> spp. to modulate chemokine production (CCL17) in vitro. This work highlights the effector T cell response directed to skin and mucosal tissues in TL, emphasizing the role of cytotoxic functions in ML. …”
Get full text
Article -
12923
Treatment of Chronic Neck Pain with Transcranial Direct Current Stimulation: A Single-Blinded Randomized Clinical Trial
Published 2025-07-01“…The aim of this study was to analyze the effects of tDCS on functionality, pain, mobility, and pressure pain threshold in patients with chronic nonspecific neck pain. …”
Get full text
Article -
12924
HIV-1 matrix protein p17: a key factor in HIV-associated cancers
Published 2025-05-01“…The sustained detection of p17 in clinical specimens—particularly lymph node biopsies and plasma samples from HIV/AIDS patients—points to its possible involvement in tumor microenvironment modulation. Here, we present a brief overview of the roles played by p17 in the regulation of cellular functions, promotion of lymphoma occurrence, and formation of the tumor microenvironment, as well as the potential molecular mechanisms which are fundamental to the functionality of p17. …”
Get full text
Article -
12925
Repositioning Canagliflozin for Mitigation of Aluminium Chloride-Induced Alzheimer’s Disease: Involvement of TXNIP/NLRP3 Inflammasome Axis, Mitochondrial Dysfunction, and SIRT1/HMG...
Published 2024-11-01“…<i>Results:</i> Canagliflozin administered to aluminium chloride-treated animals induced dose-dependent normalisation in the behavioural tests, augmentation of the antioxidant defence mechanisms, inhibition of TXNIP/NLRP3 inflammasome signalling, modulation of the SIRT1/HMGB1 axis, interference with the pro-inflammatory and the pro-apoptotic mechanisms, and restoration of the mitochondrial functions and autophagy in the hippocampal tissues to approximately baseline values. …”
Get full text
Article -
12926
KSRP Deficiency Attenuates the Course of Pulmonary Aspergillosis and Is Associated with the Elevated Pathogen-Killing Activity of Innate Myeloid Immune Cells
Published 2024-12-01“…The mRNA-binding protein KSRP (KH-type splicing regulatory protein) is known to modulate immune cell functions post-transcriptionally, e.g., by reducing the mRNA stability of cytokines. …”
Get full text
Article -
12927
PKM2-driven metabolic reprogramming in digestive system tumors: mechanisms, therapeutic advances, and clinical challenges
Published 2025-08-01“…These functions contribute to tumor adaptation within the microenvironment and promote immune evasion. …”
Get full text
Article -
12928
Electric-stimulated controllable synaptic GaN nanodevice for neuromorphic computing
Published 2025-12-01“…Due to a range of distinctive advantages, synaptic nanodevices hold substantial promise in the fields of neuromorphic computing systems that parallel the functionality of the human brain. In this work, we have demonstrated a cost-efficient method for preparing the artificial synaptic nanodevice based on gallium nitride (GaN) nanowire successfully. …”
Get full text
Article -
12929
Comprehensive review of macrophage models: primary cells and immortalized lines across species
Published 2025-08-01“…Because of their flexibility and diversity, macrophages participate in a variety of physiological and pathological processes by changing phenotypically and functionally in response to microenvironmental stimuli. …”
Get full text
Article -
12930
Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy
Published 2025-05-01“…Although numerous reviews exist on purinoceptors that modulate these functions, there is an apparent gap relating to the involvement of astrocyte‐derived extracellular ATP. …”
Get full text
Article -
12931
Activation of <i>BmToll9-1</i> in Silkworm (<i>Bombyx mori</i>) Larval Midgut by <i>Escherichia coli</i> and Regulation of Growth
Published 2025-06-01“…Our previous studies have shown that <i>BmToll9-1</i> functions as a positive regulator in the Toll pathway. …”
Get full text
Article -
12932
The dual role of extracellular vesicles derived from animal and human immune cells: A systematic review
Published 2025-04-01“…This review aims to examine the functions of extracellular vesicles (EVs) originating from animal and human immune cells, with a focus on their roles in immunomodulation and therapeutic potential. …”
Get full text
Article -
12933
Advanced smart assistance with enhancing social interaction and daily activities for visually impaired individuals using deep learning with modified seagull optimization
Published 2025-05-01“…The ADD-MSGOEL method is designed to enhance the social life and daily functioning of visually impaired people by accurately detecting damage and potential hazards in their surroundings. …”
Get full text
Article -
12934
Epigenetic Regulation of Neutrophils in ARDS
Published 2025-07-01“…Beyond their classical antimicrobial functions, neutrophils contribute to pulmonary injury via the release of reactive oxygen species, proteolytic enzymes, and neutrophil extracellular traps (NETs). …”
Get full text
Article -
12935
Glycosylation in T2 high and Th17 Asthma: A Narrative Review
Published 2025-04-01“…We examined glycosylation’s involvement in regulating airway inflammation, encompassing the modulation of pro-inflammatory cytokine release such as IL-4, IL-5, and IL-13, key components of T2 inflammation, as well as its significance in modulating immune cell functionality, notably T cells and dendritic cells. …”
Get full text
Article -
12936
Advanced DFE, MLD, and RDE Equalization Techniques for Enhanced 5G mm-Wave A-RoF Performance at 60 GHz
Published 2025-05-01“…The enhanced functionalities of DFE, RDE, and MLD in managing greater modulation orders and expanding transmission range highlight their efficacy in improving the performance and dependability of our system.…”
Get full text
Article -
12937
Intelligent Prediction Platform for Sepsis Risk Based on Real-Time Dynamic Temporal Features: Design Study
Published 2025-05-01“…MethodsWithin a retrospective analysis framework, the model comprises a real-time prediction module and an interpretability module. The real-time prediction module leverages 3-hour dynamic temporal features derived from 8 noninvasive, real-time physiological indicators: heart rate, respiratory rate, blood oxygen saturation, mean arterial pressure, systolic blood pressure, diastolic blood pressure, body temperature, and blood glucose. …”
Get full text
Article -
12938
Ceramide signaling in immunity: a molecular perspective
Published 2025-07-01“…In recent years, ceramides have garnered attention for their role in modulating a range of cellular and organismal functions. …”
Get full text
Article -
12939
1,8-Cineole inhibits platelet-leukocyte aggregate formation by reducing P-selectin expression
Published 2025-06-01“…Beyond releasing growth factors and chemokines, platelets modulate leukocyte-mediated proinflammatory responses and effector functions through direct or indirect contact. …”
Get full text
Article -
12940
Molecular and Cellular Aspects of Socket Healing in the Absence and Presence of Graft Materials and Autologous Platelet Concentrates: a Focused Review
Published 2019-09-01“…Objectives: The present manuscript aims to critically detail the physiologic process of socket healing, in the absence or presence of grafting materials or platelet concentrates, addressing the associated molecular and cellular events that culminate in the restoration of the lost tissue architecture and functionality. Material and Methods: An electronic search in the National Library of Medicine database MEDLINE through its online site PubMed and Web of Science from inception until May 2019 was conducted to identify articles concerning physiologic process of socket healing, in the absence or presence of grafting materials or platelet concentrates. …”
Get full text
Article