Cancer-associated fibroblasts: dual roles from senescence sentinels to death regulators and new dimensions in therapy by Guixiang Ruan, Xiang Wang, Huiyi Ou, Huiyi Ou, Duancheng Guo, Duancheng Guo, Duancheng Guo

“…This review provides a comprehensive analysis of CAFs functions and their potential as therapeutic targets, offering valuable insights into the development of novel anti-cancer strategies.…”
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Natural killer cell cytokine response to M. bovis BCG Is associated with inhibited proliferation, increased apoptosis and ultimate depletion of NKp44(+)CD56(bright) cells. by Damien Portevin, Douglas Young

“…In summary, we observed that M. bovis BCG is modulating the functions of CD56(bright) NK cells to drive this subset to produce IFN-γ before subsequent programmed cell death. …”
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Mitochondrial inhibitors reveal roles of specific respiratory chain complexes in CRY-dependent degradation of TIM by Xiangzhong Zheng, Dechun Chen, Brian Zoltowski, Amita Sehgal

“…Interestingly, we found that transcriptional repressor functions of Drosophila and mammalian CRY proteins are not affected by mitochondrial inhibitors. …”
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Cellular and molecular roles of reactive oxygen species in wound healing by Matthew Hunt, Monica Torres, Etty Bachar-Wikstrom, Jakob D. Wikstrom

“…Whilst advances in targeting ROS and oxidative stress have led to the development of novel pre-clinical therapeutic methods, due to the complex nature of ROS in wound healing, gaps in knowledge remain concerning the specific cellular and molecular functions of ROS in wound healing. In this review, we highlight current knowledge of these functions, and discuss the potential future direction of new studies, and how these pathways may be targeted in future pre-clinical studies.…”
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Brain-Computer Interface: A Revolutionary Technology Expanding the Frontiers of the Human Brain and the Future of Neurosurgery by ZHAO Jizong

“…From repairing neural damage to modulating brain functions, from enhancing human intelligence to shaping the future of human-machine integration, BCI offers unprecedented possibilities for neurosurgery. …”
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The role of calmodulin and calmodulin-dependent protein kinases in the pathogenesis of atherosclerosis by Mei-Fang Chen

“…Calmodulin (CaM), as a versatile Ca2+ sensor in diverse cell types, regulates a broad spectrum of Ca2+-dependent cell functions through the actions of downstream protein kinases. …”
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Targeted Sensory System Neuromodulation Improves Sensorimotor and Cognitive Deficits After Brain Injury: Bridging Mechanisms to Practice by Qin Zhang, Zhen Pang, Rongrong Lu, Hua He, Ulf Ziemann, Zhengrun Gao

“…Preclinical and clinical trails have demonstrated that sensory modulation strategies can restore sensorimotor and cognitive functions after brain injury. …”
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Geometry of concircular curvature tensor of Nearly Kahler manifold by Taha H. Jasim, Ali A. Shihab, Rawaa A. Zabin

“…Let M - smooth manifold of dimension 2n;  - algebra of smooth functions on M;  - the module of smooth vector fields on manifold of M; g = <·, > - Riemannian metrics; Ñ – Riemannian connection of the metrics g on M; d - the operator of exterior differentiation. …”
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Sonogenetics in the Treatment of Chronic Diseases: A New Method for Cell Regulation by Mingrui Zhu, Yan Fang, Yikang Sun, Shaoyue Li, Jifeng Yu, Bing Xiong, Congjian Wen, Boyang Zhou, Bin Huang, Haohao Yin, Huixiong Xu

“…Abstract Sonogenetics is an innovative technology that integrates ultrasound with genetic editing to precisely modulate cellular activities in a non‐invasive manner. …”
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Roles of hypoxia inducible factors in viral infection: Are they a potential therapeutic target? by Sikai Jia, Shuo Pan, Zhiyun Gao, Hongxiu Qiao, Yan Zhao, Xia Chuai, Jian Li

“…As a crucial nuclear transcription factor, hypoxia-inducible factor (HIF) serves essential functions in mediating cellular responses to hypoxic stress. …”
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Amelioration of gut dysbiosis-induced cognitive deterioration by repeated administration of human clostridium butyricum: targeting intestinal and blood–brain barrier by Dalia Azmy Elberry, Maha Gamal, Zeinab Gawish, Esraa A. Hegazy, Sara Adel Hosny, Laila Ahmed Rashed, Marwa Nagi Mehesen, Asmaa Mohammed ShamsEldeen

“…Intake of a high-fat diet (HFD) leads to an imbalance of gut microbiota and regression of bacteria producing “short-chain fatty acids (SCFAs)”. These SCFAs can modulate brain functions. Therefore, we investigated the therapeutic effect of Clostridium Butyricum (CB) bacteria extracted from human faeces on intestinal and neurological impairments induced by HFD and explored their modulation of tight junction protein expression. …”
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Proteomic Profile Regulated by the Immunomodulatory Jusvinza Drug in Neutrophils Isolated from Rheumatoid Arthritis Patients by Mabel Hernández-Cedeño, Arielis Rodríguez-Ulloa, Yassel Ramos, Luis J. González, Anabel Serrano-Díaz, Katharina Zettl, Jacek R. Wiśniewski, Gillian Martinez-Donato, Gerardo Guillen-Nieto, Vladimir Besada, María del Carmen Domínguez-Horta

“…A total of 149 proteins were found to be differentially modulated in neutrophils treated with Jusvinza. The proteomic profile regulated by Jusvinza is characterized by the presence of proteins related to RNA splicing, phagocytosis, endocytosis, and immune functions. …”
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The small RNA complement of adult Schistosoma haematobium. by Andreas J Stroehlein, Neil D Young, Pasi K Korhonen, Ross S Hall, Aaron R Jex, Bonnie L Webster, David Rollinson, Paul J Brindley, Robin B Gasser

“…Of the sncRNAs that were not miRNAs, some related to the spliceosome (n = 21), biogenesis of other RNAs (n = 3) or ribozyme functions (n = 16), whereas most others (n = 3798) were novel ('orphans') with unknown functions.…”
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Amantadine produces analgesia through a unique mechanism and pharmacokinetics in chickens by Faisal F. Idris, Yaareb J. Mousa

“…The study concluded the safety of AMN (liver and kidney functions besides its pharmacokinetics) with its unique capability to modulate the activity of brain COX-2 which makes it a good analgesic, and probably anti-inflammatory drug to be used in chickens.…”
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Ring-finger protein RNF126 promotes prostate cancer progression via regulation of MBNL1 by Xin Jiang, Ji Li, Jiali Zhang, Yulei Zhao, Guoqin He, Xiaohui Yao

“…However, although some functions of RNF126 in prostate cancer (PCa) cell lines has been reported, more biological functions and in-depth mechanisms should be further clarified in PCa. …”
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Glycine betaine in plant responses and tolerance to abiotic stresses by Afsana Jarin, Uttam Kumar Ghosh, Md. Saddam Hossain, Apple Mahmud, Md. Arifur Rahman Khan

“…It explores the morpho-physiological, biochemical, and molecular factors associated with GB's role in mitigating the impact on the structure and functionality of photosystem II (PSII). Furthermore, this review examines GB's modulation of chaperone functions within plant cells, preventing misfolded protein formation and safeguarding crucial complexes like PSII from structural damage, as well as its interaction with other molecules whose functions are impaired during abiotic stress conditions.…”
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Optimization Method of High-Speed Train Composite Material Workshop Planning and Scheduling by Yanliang Jie, Lei Hao, Shujun Yan, Xueli Zhang

“…The interface parameters of each module are checked, and the boundary values of some functions are also analyzed and tested. …”
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Synergistic effect of vermicompost and calcium for improving salinity tolerance in Yunnanopilia longistaminea by Jiangshan Xie, Liu Yang, Shirui Tan, Chigui Xiao, Zhiyuan Liu, Likai Xu, Qamar uz Zaman, Khawar Sultan, Shah Fahad, Shikang Shen, Gang Deng

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The role of laminins in cancer pathobiology: a comprehensive review by Elena Nonnast, Emilia Mira, Santos Mañes

“…In this article, we review the diverse functions of LMs in promoting cancer cell proliferation, adhesion, and migration—critical steps in cancer metastasis. …”
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Deep Learning-Based Gain Estimation for Multi-User Software-Defined Radios in Aircraft Communications by Viraj K. Gajjar, Kurt L. Kosbar

“…It may be helpful to integrate multiple aircraft communication and navigation functions into a single software-defined radio (SDR) platform. …”
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