TREM2 signaling pathway in sepsis-induced acute lung injury: physiology, pathology, and therapeutic applications by Hong-Lei Shen, Jing He, Fei Lin

“…This article endeavors to elucidate the intricate interplay between sepsis, lung injury, and TREM2's role in immune modulation. It will furnish an overview of the TREM2 signaling pathway's functions and mechanisms in both physiological and septic lung injury scenarios, while also evaluating the current status and advancements in TREM2-targeted therapies.…”
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Glycans on death receptors as sweet markers and signaling checkpoints by Kamil Seyrek, Johannes Espe, Corinna König, Fabian Wohlfromm, Inna N. Lavrik

“…Due to the tremendous structural diversity of glycans attached to DRs, little is known about the role of specific glycosylation subtypes influencing functions of DRs. Deciphering the role of specific glycan signatures, so-called “glyco-code”, on DRs is important to understand how glycans are involved in signal transduction. …”
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Galectin-12 in the Regulation of Sebocyte Proliferation, Lipid Metabolism, and Immune Responses by Ching-Han Tsao, Wei-Chen Hsieh, Feng-Jen Lin, Fu-Tong Liu, Ri-Yao Yang

“…Galectin-12, a member of the galectin family of glycan-binding proteins, exhibits restricted tissue distribution, primarily in adipocytes and sebocytes. In sebocytes, it modulates the cell cycle, influences lipid metabolism through interactions with peroxisome proliferator-activated receptor γ (PPARγ), and exerts immunomodulatory functions by activating immune signaling pathways. …”
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Cytokine Interactions with Epithelium by Kim E Barrett

“…Topics include epithelial functions subject to modulation by cytokines; effects of cytokines on epithelial damage, restitution and proliferation; effects of cytokines on the ability of the epithelium to express immune accessory and adhesion molecules; and effects of cytokines on the production of inflammatory mediators by the epithelium.…”
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Light Combining for Interferometric Switching by Marco Masi, Mattia Mancinelli, Paolo Bettotti, Lorenzo Pavesi

“…The two bus interferometric switching functions of SCISSOR and CROW resonant structures are investigated. …”
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Gut microbiota and the “gut-liver-kidney axis” theory: from mechanisms to therapeutics by Dai-Liang Fei, Ying Liu, Jia Liu, Ze Yu, Jin-Liang Dong

“…In this research, we aim to examine how the gut microbiota affects metabolic and immune responses via influencing the functions of the liver and kidneys. It will also analyze potential pathological mechanisms involved in this interaction and discuss therapeutic strategies that focus on modulating the gut microbiota. …”
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Transcranial Magnetic stimulation in Neurodegenerative Diseases: Basics and Clinical Applications by Burak Yuluğ, Ahmet Aslan

“…Transcranial Magnetic Stimulation (rTMS) non-invasively modulates brain networks via stimulating relevant brain regions responsible for motor and cognitive functions. …”
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The Role of Magnesium in Liver Cirrhosis by Weiye Zeng, Xudan Wang, He Qi, Hongtao Tang, Xun Qi

“…This is integral to numerous physiological functions. Disruptions in magnesium homeostasis are prevalent under various conditions, and a multitude of physiological processes are compromised when magnesium levels are insufficient. …”
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THE MOTION LAWSSYNTHESIS IN THE POSITIONING MECHANISM MOTOR COUPLES 3R by Elisabeta NICULAE (BANICA), Andrei DIMITRESCU, Ana-Maria ALECUSAN, Claudiu BABIS, Loredana DASCALU

“…With the cinematically modulations you can calculate command functions (position, velocity and acceleration in motor couple) from the condition that tracer point make a movement after a law named movement law. …”
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Following the robot’s lead: Predicting human and robot movement from EEG in a motor learning HRI task by Tanaya Chatterjee, Adrien Guzzo, Alejandro Tlaie, Ahmad Kaddour, Charalambos Papaxanthis, Jeremie Gaveau, Peter Ford Dominey

“…Learning new behavioral sequences recruits cognitive functions with their neural underpinnings. Here, we characterize how neurophysiological activity revealed in the EEG signal can reflect these behavioral processes. …”
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Aberrant histone modifications in pediatric brain tumors by Erin T. Hamanishi, Erin T. Hamanishi, Erin T. Hamanishi, Erin T. Hamanishi, Derek Dang, Derek Dang, Derek Dang, Sriram Venneti, Sriram Venneti, Sriram Venneti, Sriram Venneti

“…Key enzymes, including histone methyltransferases and demethylases, and associated proteins exemplify the functions of writers, readers, and erasers in maintaining histone modification balance. …”
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Zinc-doped curcumin carbon dots promote infected wound healing with photodynamic via the VEGF signaling pathway by Yifan Zhao, Jia Liu, Lingxiang Sun, Haiyan Liu, Xi Chen, Xuedong Deng, Yilin Ping, Wenze Han, Jing Wang, Feng Tian, Jingyu Yan, Xiuping Wu, Bing Li

“…Here, we describe zinc-doped curcumin carbon dots (CCDs) as a novel nanoscale photosensitizer, which was applied in photodynamic therapy (PDT) to promote infected wound healing by modulating various cellular functions. The PDT generation of reactive oxygen species (ROS) effectively inactivates the source of infection without drug resistance, effectively inhibiting the propagation of bacteria and the spread of inflammation in the wound. …”
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Gut–Adipose Tissue Axis and Metabolic Health by Sanja Borozan, Cornelius J. Fernandez, Adnan Samee, Joseph M. Pappachan

“…This article highlights the need for integrative approaches that consider both gastrointestinal and adipose functions in metabolic health management.…”
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The Role of Rho GTPases in VEGF Signaling in Cancer Cells by Nada El Baba, Mohammad Farran, Elie Abi Khalil, Leila Jaafar, Isabelle Fakhoury, Mirvat El-Sibai

“…Vascular endothelial growth factors (VEGFs) consist of five molecules (VEGFA through D as well as placental growth factor) which are crucial for regulating key cellular and tissue functions. The role of VEGF and its intracellular signaling and downstream molecular pathways have been thoroughly studied. …”
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The Role of Cyclooxygenase-2 in Cell Proliferation and Cell Death in Human Malignancies by Cyril Sobolewski, Claudia Cerella, Mario Dicato, Lina Ghibelli, Marc Diederich

“…This family contains three members: ubiquitously expressed COX-1, which is involved in homeostasis; the inducible COX-2 isoform, which is upregulated during both inflammation and cancer; and COX-3, expressed in brain and spinal cord, whose functions remain to be elucidated. COX-2 was described to modulate cell proliferation and apoptosis mainly in solid tumors, that is, colorectal, breast, and prostate cancers, and, more recently, in hematological malignancies. …”
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Bitter Taste Receptors in Bacterial Infections and Innate Immunity by Erin Rudolph, Hannah Dychtenberg, Austin Pozniak, Priyanka Pundir

“…ABSTRACT Background Bitter taste receptors (TAS2Rs), originally identified for their role in gustation, are now recognized for their functions in extraoral tissues, particularly in innate immune responses. …”
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Microbiome, immune system and cancer: three sides of the one medal by V. A. Belyavskaya, N. V. Cherdyntseva, J. G. Kzhyshkovska, N. V. Litvyakov

“…The microbiome is an important factor in cancer pathogenesis due to its involvement in the basic physiological functions of the host, such as digestion, development of the immune system, and modulation of endocrine functions. …”
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miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin. by Tianhao Sun, Chen-Tian Li, Lifeng Xiong, Ziyu Ning, Frankie Leung, Songlin Peng, William W Lu, William W Lu

“…The mRNA levels of important negative modulators relating to osteogenesis increased after the functions of LRP5 were blocked in mice. …”
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The role of type I interferon signaling in myeloid anti-tumor immunity by Sofie Patrizia Meyer, Rebekka Bauer, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Tobias Schmid, Tobias Schmid

“…Type I interferons (IFNs) are well established modulators of inflammatory reactions. While they have been shown to directly inhibit tumor growth, there is accumulating evidence that they also play an important role in altering immune cell functions within the TME. …”
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Anti-Inflammatory and Antimicrobial Effects of Estradiol in Bovine Mammary Epithelial Cells during Staphylococcus aureus Internalization by Ivan Medina-Estrada, Joel E. López-Meza, Alejandra Ochoa-Zarzosa

“…In bovine mammary epithelial cells (bMECs), E2 regulates differentiation and proliferation, but its immunomodulatory functions have not been explored. Staphylococcus aureus is the predominant pathogen causing mastitis, which can persist intracellularly in bMECs. …”
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