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Inhibiting CD36 palmitoylation improves cardiac function post-infarction by regulating lipid metabolic homeostasis and autophagy
Published 2025-07-01“…Mechanistically, the inhibition of CD36 palmitoylation enhances cardiac function through a dual mechanism: first, by alleviating fatty acid overload mediated by plasma membrane CD36, thereby restoring lipid metabolic balance; second, by augmenting the activity of the mitochondrial CD36-PGAM5 signaling axis and modulating Fundc1 and Drp1 Dephosphorylation, which subsequently improves mitophagy efficiency. …”
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The innexin 7 gap junction protein contributes to synchronized activity in the Drosophila antennal lobe and regulates olfactory function
Published 2025-04-01“…These results demonstrate that Inx7-encoded gap junctions functionally coordinate PN activity and modulate olfactory information processing in the adult Drosophila AL.…”
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The Gut–Brain Axis and Probiotics in Beverages and Liquid Preparations: A PRISMA Systematic Review on Cognitive Function Enhancement
Published 2025-06-01“…The gut–brain axis links the health of the gut microbiota to cognitive function and mental well-being. Numerous studies suggest that probiotics, particularly strains belonging to <i>Lactobacillus</i> spp. and <i>Bifidobacterium</i> spp., can positively modulate memory, attention, and executive functions, contributing to the prevention of cognitive decline. …”
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The Role of Milk Oligosaccharides in Enhancing Intestinal Microbiota, Intestinal Integrity, and Immune Function in Pigs: A Comparative Review
Published 2024-08-01“…The consumption of milk oligosaccharides during suckling and through the nursery phase can provide benefits to young pigs by encouraging the proliferation of beneficial microbial populations, preventing pathogen adhesion to enterocytes, and through directly modulating immune responses. Therefore, this review aims to summarize the specific functional components of milk oligosaccharides from human, bovine, and porcine sources, and identify potential strategies to utilize milk oligosaccharides to benefit young pigs through the suckling and nursery periods.…”
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SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function.
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1250
Cigarette Smoke Exposure Leads to Organic and Mineral Bone Component Changes: The Importance of Rho Kinase Function in These Events
Published 2025-03-01“…Aberrant Rho-associated kinase function could be associated with increased bone fragility. …”
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Context-dependent PSIICOS: A novel framework for functional connectivity estimation accounting for task-related power leakage
Published 2025-08-01“…Functional connectivity (FC) analysis using non-invasive neuroimaging methods, such as MEG and EEG, is often confounded by artifacts from spatial leakage and task-related power modulations. …”
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HSV-1 alters lipid metabolism and induces lipid droplet accumulation in functionally impaired mouse dendritic cells
Published 2025-05-01“…Summary: Herpes simplex virus type 1 (HSV-1) significantly impairs dendritic cell (DC) function, ultimately eliciting the death of these cells. …”
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Evenly Distributed Microporous Structure and E7 Peptide Functionalization Synergistically Accelerate Osteogenesis and Angiogenesis in Engineered Periosteum
Published 2025-03-01“…The E7 peptide (EPLQLKM), which exhibits a specific affinity for mesenchymal stem cells (MSCs), is beneficial for modulating cellular functions. In this study, a unique microporous structured carboxymethyl chitosan/sodium alginate membrane with a proper mass ratio is developed by the addition of Poloxam 407 (P407), which is then functionalized with the E7 affinitive peptide. …”
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Evaluation of autonomic nervous system functions in frame of heart rate variability in children with inflammatory bowel disease in remission
Published 2018-08-01“…The aim of our study was to assess autonomic function in pediatric patients with inflammatory bowel disease (IBD) in remission using Power Spectral Analysis of HRV. …”
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Exploring the potential of anthocyanin-infused fermented beverages for sustainable health solutions: A pathway to functional food development
Published 2025-12-01“…This review particularly highlights the health promoting potential of anthocyanin-rich fermented dairy and non-dairy fermented beverages such as kefir, kombucha, and kvass focusing on their health benefits such as cognitive function, type 2 diabetes (T2DM) and cancer. And also, emphasizes the functional roles of beverages in gut microbiota modulation, metabolic and neurotransmitter regulation, oxidative stress reduction and signaling pathways (e.g., NF-κB, PI3K/AKT). …”
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Using Postbiotics from Functional Foods for Managing Colorectal Cancer: Mechanisms, Sources, Therapeutic Potential, and Clinical Perspectives
Published 2025-06-01“…This systematic review investigates the therapeutic potential of postbiotics derived from functional foods in the context of colorectal cancer (CRC), a leading cause of cancer-related mortality worldwide. …”
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ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice
Published 2024-12-01“…However, its functional role within mesoaccumbens circuitry critical for motivated behaviour and considerably modulated by endocannabinoids was unknown. …”
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