SLAMF receptors: key regulators of tumor progression and emerging targets for cancer immunotherapy by Jia Li, Tao Fan, Di Wang, Chu Xiao, Ziqin Deng, Wenpeng Cai, Yu Ji, Chunxiang Li, Jie He

“…Abstract The signaling lymphocytic activation molecule family (SLAMF) consists of nine distinct cell surface receptors predominantly expressed on immune cells, each characterized by unique structural features, expression patterns, downstream signaling pathways, and biological functions. These receptors play critical roles in modulating various immune cell activities within the tumor microenvironment, thereby shaping immune responses in cancer. …”
Get full text

An Assistant Decision-making System for Black-Start Path Generation and System Restoration by Yinxing XIANG, Xiaojian TANG, Jikeng LIN

“…Firstly, The overall framework architecture of the system is introduced; And then, the module functions and its implementation methods of the system are further described in detail, including data base, graph platform, and algorithm library that is composed of initial path generation, path check and assessment, and system restoration; Finally, an actual power system is used to verify the effectiveness and correctness of the designed system. …”
Get full text

Miha: An Affordable Humanoid Platform for Research and Development by Alexandru Sonea, Nicolae Goga, Ramona Cristina Popa, Iuliana Marin, Ioana Petre, Cristian Gheorghe, George Suciu, Victor Suciu

“…We demonstrate several control functions, including walking. The vast majority of hardware and software components are either off-the-shelf or provided as open-source.…”
Get full text

Osteocalcin and metabolic syndrome by Consolim-Colombo Fernanda M., Lopes Heno Ferreira

“…This mini-review examines the multifaceted roles of osteocalcin, a bone-derived protein that functions as a critical mediator between skeletal biology and systemic metabolism. …”
Get full text

Dual Role of Lysosome in Cancer Development and Progression by Xiao-Qiong Chen, Quan Yang, Wei-Min Chen, Zi-Wei Chen, Guang-Hui Guo, Xuan Zhang, Xiao-Ming Sun, Tao Shen, Fu-Hui Xiao, Yun-Feng Li

“…However, what is noteworthy is that the modulation of lysosome-based signaling and degradation has both the cancer-suppressive and cancer-promotive functions in diverse cancers depending on stage, biology, or tumor microenvironment. …”
Get full text

Design of a wireless intelligent monitoring and control system for adjustable voltage DC-DC power supply by Si Ming, Wang Xusheng, Wang Jingjing

“…To solve the above problems and combined with the characteristics of this system itself, a design scheme for a wireless intelligent measurement and control system of an adjustable voltage DC-DC power supply based on "5G module + STM32 + PC" is proposed. The measurement and control functions for remote devices are achieved through the intelligent measurement and control software on the upper computer at the user end. …”
Get full text

Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration by Vanlalrinchhani Varte, Diego E. Rincon-Limas, Diego E. Rincon-Limas, Diego E. Rincon-Limas

“…Comprising eight distinct subunits (CCT1 - CCT8), TRiC assists in the folding of a wide range of client proteins, ensuring their proper conformation and functionality. This mini review explores the assembly, structure, and cellular functions of TRiC and discusses its involvement in protein aggregation and neurodegenerative diseases. …”
Get full text

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds by Rodrigo Arreola, Saray Quintero-Fabián, Rocío Ivette López-Roa, Enrique Octavio Flores-Gutiérrez, Juan Pablo Reyes-Grajeda, Lucrecia Carrera-Quintanar, Daniel Ortuño-Sahagún

“…In this review, we assess the most recent experimental results, which indicate that garlic appears to enhance the functioning of the immune system by stimulating certain cell types, such as macrophages, lymphocytes, natural killer (NK) cells, dendritic cells, and eosinophils, by mechanisms including modulation of cytokine secretion, immunoglobulin production, phagocytosis, and macrophage activation. …”
Get full text

Interactions Between Iron Metabolism and the Endocannabinoid System in Bacterial Infections by Kayle Brenna Dickson, Juan Zhou, Christian Lehmann

“…Iron is a key nutritional requirement for a variety of physiological functions, and its metabolism is tightly controlled under homeostatic conditions. …”
Get full text

AozC, a zn(II)2Cys6 transcription factor, negatively regulates salt tolerance in Aspergillus oryzae by controlling fatty acid biosynthesis by Wenbin Yu, Zeying Zhao, Yufei Zhang, Yayi Tu, Bin He

“…The Zn(II)2Cys6 family of transcription factors, known for their zinc binuclear cluster-containing proteins, are key regulators in fungi, modulating various cellular functions such as stress adaptation and metabolic pathways. …”
Get full text

Canonical and non-canonical roles of oligodendrocyte precursor cells in mental disorders by Giulia Poggi, Giulia Treccani, Martina von der Bey, Arnaud Tanti, Michael J. Schmeisser, Marianne Müller

“…Oligodendrocyte precursor cells (OPCs)— actively involved in the modulation of neuronal functions – are altered in psychiatric patients, but the extent and related consequences are unclear. …”
Get full text

A multi-omics approach to unravel the interaction between heat and drought stress in the Arabidopsis thaliana holobiont by Biancamaria Senizza, Fabrizio Araniti, Simon Lewin, Sonja Wende, Steffen Kolb, Steffen Kolb, Luigi Lucini

Get full text

Development of a decellularized extracellular matrix-derived wet adhesive for sustained drug delivery and enhanced wound healing by Xinming Wang, Haonan Zhang, Weichang Xie, Bei Qian, Shixing Huang, Qiang Zhao, Xiaofeng Ye

“…ECM-dopamine loaded with insulin-like growth factor-1 promotes skeletal muscle regeneration in a mouse volumetric muscle loss model, likely through the modulation of M2-like macrophage polarization. The dual functionality of ECM-dopamine as both a wet adhesive and a drug delivery platform offers significant potential for regenerative medicine applications.…”
Get full text

F-box proteins at the crossroads of ubiquitination and tumor immunity: regulatory networks and immunotherapy strategies by Mingzheng Dai, Mingzheng Dai, Mingzheng Dai, Shimin Chen, Shimin Chen, Shimin Chen, Yuanjing Wang, Yuanjing Wang, Yuanjing Wang, Jinxuan Fan, Jinxuan Fan, Jinxuan Fan, Xin Pan, Chenhui Sang, Yuchen Liu, Ming Hu, Leina Ma, Leina Ma, Shasha Wang, Shasha Wang

“…On the other hand, F-box proteins directly regulate tumor immune microenvironments by targeting immune-related molecules for degradation, thereby modulating T-cell activation, macrophage polarization, and immune checkpoint functionality (specifically PD-1/PD-L1 axis and CTLA-4 signaling). …”
Get full text

Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of myocardial infarction by Maryam Zolfaghari Dehkharghani, Safa Mousavi, Nazanin Kianifard, Amin Fazlzadeh, Hamid Parsa, Ali Tavakoli Pirzaman, Andarz Fazlollahpour-Naghibi

“…Notably, lncRNAs act as crucial modulators of gene expression and signaling cascades, functioning as decoys, regulators, and scaffolds. …”
Get full text

Regulating the regulators: long non-coding RNAs as autophagic controllers in chronic disease management by Aviral Kumar, Kenneth Chun-Hong Yap, Bandari BharathwajChetty, Juncheng Lyu, Mangala Hegde, Mohamed Abbas, Mohammed S. Alqahtani, Soham Khadlikar, Ali Zarrabi, Arezoo Khosravi, Alan Prem Kumar, Ajaikumar B. Kunnumakkara

“…Moreover, lncRNAs are known to sequester autophagy related microRNAs by functioning as competing endogenous RNAs (ceRNAs), thereby regulating this vital process. …”
Get full text

The crosstalk between glutathione metabolism and non-coding RNAs in cancer progression and treatment resistance by Lu Chang, Chao Qin, Jianbo Wu, Haoqin Jiang, Qianqian Xu, Jian Chen, Xiao Xu, Xinju Zhang, Ming Guan, Xuan Deng

“…In this review, we summarize the functions of GSH metabolism and highlight the significance of ncRNA-mediated regulation of GSH in cancer progression, drug resistance, and clinical applications.…”
Get full text

The Role of Bacteriophage-Derived Small RNA Molecules in Bacterial and Phage Interactions by Natalia Lewandowska, Sylwia Bloch, Aleksandra Łukasiak, Wojciech Wesołowski, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk

“…This review explores the diverse functions of phage-encoded sRNAs, highlighting recent discoveries and their impact on bacterial physiology and phage-host interactions.…”
Get full text

Harnessing theta waves: tACS as a breakthrough in alleviating post-stroke chronic pain by Ningjing Song, Ningjing Song, Ningjing Song, Ningjing Song, Ling Long, Ling Long, Ling Long, Ling Long, Nianquan Liu, Nianquan Liu, Nianquan Liu, Nianquan Liu, Yujun Luo, Yujun Luo, Yujun Luo, Yujun Luo, Meng Wei, Meng Wei, Meng Wei, Meng Wei, Hai Huang, Hai Huang, Hai Huang, Hai Huang, Wan Liu, Wan Liu, Wan Liu, Wan Liu

“…Neural oscillations play a critical role in the regulation of brain functions, with theta waves (4–8 Hz) in the sensorimotor cortex significantly influencing pain perception and modulation. …”
Get full text

The Role of Protein Arginine Methyltransferases in Inflammatory Responses by Ji Hye Kim, Byong Chul Yoo, Woo Seok Yang, Eunji Kim, Sungyoul Hong, Jae Youl Cho

“…Protein arginine methyltransferases (PRMTs) mediate the methylation of a number of protein substrates of arginine residues and serve critical functions in many cellular responses, including cancer development, progression, and aggressiveness, T-lymphocyte activation, and hepatic gluconeogenesis. …”
Get full text