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12401
Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance
Published 2025-06-01“…IntroductionEmerging evidence suggests a complex interplay among cardiovascular health, gut microbiome composition, and cognitive function. Life’s Essential 8 (LE8), developed by the American Heart Association, includes vital metrics of cardiovascular health, such as diet, physical activity, nicotine exposure, sleep health, body mass index (BMI), blood glucose, blood lipids, and blood pressure. …”
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12402
Neural correlates of human fear conditioning and sources of variability in 2199 individuals
Published 2025-08-01“…We investigate its neural correlates and sources of variability using harmonized functional magnetic resonance imaging data from 2199 individuals across nine countries, including 1888 healthy individuals and 311 with anxiety-related or depressive disorders. …”
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12403
Inhibition of Ferroptosis by Adipose Stem Cell-Derived Apoptotic Vesicles Enhances Angiogenesis and Accelerates Diabetic Wound Healing
Published 2025-08-01“…ApoVs represent a promising cell-free therapeutic approach to mitigate ferroptosis, restore endothelial function and promote angiogenesis, offering a potential strategy for diabetic wound management.Keywords: apoptotic vesicles, wound healing, vascularization, adipose stem cells, ferroptosis, endothelial cells…”
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12404
B-lymphocyte subpopulations in patients with rheumatoid arthritis and the effect of an interleukin-6 receptor inhibitor on them.
Published 2019-01-01“…Preliminary reports have shown that B cell function and a humoral immune response may be modulated by an IL-6 receptor inhibitor.Objective: to assess the effect of 12-month tocilizumab (TCZ) therapy on B-cell phenotype and gene expression in RA and to analyze the association between B-cell subsets and RA activity.Subjects and methods. …”
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12405
Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury
Published 2025-04-01“…In this study, we explored the roles of S100A8/A9 in modulating neuroinflammation and influencing TBI outcomes, delving into the underlying mechanisms. …”
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12406
Effect of the Foliar Application of Copper Nanoparticles on the Growth and Yield of Persian Leek (Allium ampeloprasum subsp. Persicum) under Salinity Stress
Published 2024-11-01“…Copper, serving as a cofactor and essential element for numerous enzymes involved in photosynthesis and respiration processes, plays a crucial role in sustaining natural plant growth and metabolism. Copper ions function as cofactors in enzymes like superoxide dismutase (Cu/Zn SOD) and polyphenol oxidase, contributing to the removal of reactive oxygen species. …”
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12407
Myo-inositol affects the health, metabolome, and lactation performance of peripartum dairy cows
Published 2025-06-01“…However, a trend indicating a decrease in immune function was observed in the IN65 group compared to the CON group. …”
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12408
LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype
Published 2024-12-01“…BL001‐target gene expression levels were confirmed by quantitative PCR. Mitochondrial function was evaluated through the measurement of oxygen consumption rate using a Seahorse XF analyser. …”
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12409
Advance of DAM-like genes in bud dormancy of deciduous fruit trees in Rosaceae family
Published 2025-04-01“…Transgenic poplar and apple suggested the growth inhibitory functions of DAM6. The expression profile of these genes during the dormancy period indicated that DAMs served as dose-dependent inhibitors of bud break. …”
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12410
從工具示能性與關係行動主體之觀點 探討偏鄉教育系統賦能策略之研究 Investigating the Construction of Empowerment Action Models in Remote Educational Systems Through the Lenses of Tool Affordance and Relational Age...
Published 2025-03-01“…However, users’ behaviors can also exceed the original intentions of tool designers; that is, the flexible use of tools depends on users’ cognition of tool properties, the use of the tool’s own prompts, and the judgment of problems or environments to modify the use or function of the tool to achieve goals (Hammond, 2010). …”
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12411
Phase coded waveforms for integrated sensing and communication systems
Published 2024-12-01“…In studies where radar signals are utilised for communication functions, continuous wave frequency modulation or intra‐pulse frequency modulation is generally employed to transmit communication signals. …”
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12412
Low-Power Indoor Positioning Algorithm Based on iBeacon Network
Published 2021-01-01“…We analyze the platform and environment for software development, design the general framework of the positioning system, and analyze the logical structure of the whole system, the structure of data flow, and the communication protocols between each module of the positioning system. Then, we analyze the functions of the server module and the client module of the system, implement the functions of each module separately, and debug the functions of each module separately after each module is implemented. …”
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12413
T cell metabolism in kidney immune homeostasis
Published 2024-12-01“…The key enzymes and metabolites involved in T cell metabolism metabolically and epigenetically modulate T cells' differentiation, activation, and effector functions, thereby being capable of modulating kidney immune homeostasis. …”
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12414
Carbon Monoxide Targeting Mitochondria
Published 2012-01-01“…Mitochondria present two key roles on cellular functioning: (i) cell metabolism, being the main cellular source of energy and (ii) modulation of cell death, by mitochondrial membrane permeabilization. …”
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12415
Metabolism Plays a Key Role during Macrophage Activation
Published 2018-01-01“…Recently, it became clear that the main macrophage functions are under metabolic control. Modulation of glucose, fatty acid, and amino acid metabolism is associated with various macrophage activations in response to external stimuli. …”
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12416
Photonic Digitization With Differential Encoding Based on Orthogonal Vector Superposition
Published 2019-01-01“…By adjusting and combining the intensity of two orthogonal signals with an OVS module, the desired phase shifts among different transfer functions can be obtained. …”
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12417
A reconfigurable arbitrary retarder array as complex structured matter
Published 2025-05-01“…Our approach offers unprecedented functionality that is user-defined and possesses high flexibility, allowing our modulator to act as a new beam generator, analyser, and corrector, opening an exciting path to tuneable topologies of light and matter.…”
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12418
USE OF PARALLEL AND FACET ASSIGNMENTS IN THE SYSTEM OF DISTANT LEARNING “MOODLE”
Published 2016-05-01“…The paper describes features and advantages of parallel and facet tests and tasks, their implementation in various popular learning management systems. Principles of functioning and advantages of developed module for LMS Moodle are described. …”
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12419
Multifaceted Role of Notch Signaling in Vascular Health and Diseases
Published 2025-03-01“…Notch signaling is evolutionarily conserved from <i>Drosophila</i> to mammals and it functions as an essential modulator of vascular growth and development by directing endothelial cell specification, proliferation, migration, arteriovenous differentiation, inflammation, and apoptosis. …”
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12420
Sensory stimulation enhances visual working memory capacity
Published 2024-11-01“…Follow-up experiments using the Attention Network Test (ANT) and pupillometry measures did not find evidence that this effect could be directly attributed to modulation of phasic or tonic arousal. We speculate that our results differed from those obtained with tACS due to targeting functionally different theta oscillations, or the modulation of participants’ temporal expectations.…”
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