Dynamics of specialization in neural modules under resource constraints by Gabriel Béna, Dan F. M. Goodman

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DESIGN AND FEM STATIC ANALYSIS OF AN INSTRUMENT FOR SURFACE PLASTIC DEFORMATION OF NON-PLANAR FUNCTIONAL SURFACES OF MACHINE PARTS by STOYAN SLAVOV, ILIYAN ILIEV

“…The paper presents the design of a specialized instrument for formation different types of regular microshape roughness on functional surfaces of parts with non-planar macroshape by using the process, called “surface plastic deformation”. …”
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DESIGN AND FEM STATIC ANALYSIS OF AN INSTRUMENT FOR SURFACE PLASTIC DEFORMATION OF NON-PLANAR FUNCTIONAL SURFACES OF MACHINE PARTS by STOYAN SLAVOV, ILIYAN ILIEV

“…The paper presents the design of a specialized instrument for formation different types of regular microshape roughness on functional surfaces of parts with non-planar macroshape by using the process, called “surface plastic deformation”. …”
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Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. by Chris McDermott-Roe, Marion Leleu, Glenn C Rowe, Oleg Palygin, John D Bukowy, Judy Kuo, Monika Rech, Steffie Hermans-Beijnsberger, Sebastian Schaefer, Eleonora Adami, Esther E Creemers, Matthias Heinig, Blanche Schroen, Zoltan Arany, Enrico Petretto, Aron M Geurts

“…To understand the underlying mechanisms, it is essential to define the full complement of proteins that modulate mitochondrial function. To identify such proteins, we performed a meta-analysis of publicly available gene expression data. …”
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Bioinformatics analysis to investigate the potential relationship between mitochondrial structure and function-related genes and the immune microenvironment in atherosclerosis by Hanning Yang, Yue Sun, Shumin Li, Yueyue Tang, Yuxue Wang, Yunyan Li, Yongping Lu

“…ObjectiveThis study aims to elucidate the interactions between genes associated with mitochondrial structure and function and the immune microenvironment in atherosclerosis.MethodsDifferentially expressed mitochondria-related genes (DE-MRGs) were identified through the analysis of two gene expression datasets, GSE100927 and GSE159677, in conjunction with a list of mitochondria-related genes sourced from the MitoCarta3.0 database. …”
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Enhancing bioactive profiles of elderberry juice through yeast fermentation: a pathway to low-sugar functional beverages by Amir Shazad, Ali Zein Alabiden Tlais, Davide Gottardi, Pasquale Filannino, Francesca Patrignani, Rosalba Lanciotti, Marco Gobbetti, Raffaella Di Cagno

“…In response to the growing need for functional beverages, this study aimed to harness yeast metabolism to optimize elderberry juice fermentation, targeting sugar reduction and enrichment of bioactive compounds with enhanced functional properties. …”
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In-depth insight into tumor-infiltrating stromal cells linked to tertiary lymphoid structures and their prospective function in cancer immunotherapy by Maedeh Radandish, Niloofar Mashhadi, Amir Hossein Aghayan, Motahareh Taghizadeh, Sara Salehianfard, Sheida Yahyazadeh, Omid Vakili, Somayeh Igder

“…Furthermore, it highlights the dual functional roles of TLSs as sites of both anti-tumor immune activation and immunosuppression, notably via the enrichment of regulatory T cells. …”
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Antioxidant functionalized double-net/TA dynamic hydrogel promotes cartilage regeneration through stabilization of chondrocyte phenotype by Xu Wu, Honglei Wang, Chenlong Li, Yaying Zhu, Qixuan Wang, Tianyu Zhang, Yaoyao Fu, Aijuan He

“…Collectively, our study demonstrates that reducing aerobic metabolism helps stabilize the chondrocyte phenotype and promotes functional cartilage regeneration. These findings offer novel insights for optimizing cartilage tissue engineering strategies through metabolic modulation.…”
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Differential neuronal functions of LNX1 and LNX2 revealed by behavioural analysis in single and double knockout mice by Laura Cioccarelli, Joan A. Lenihan, Leah G. Erwin, Paul W. Young

“…Despite the identification of many LNX interacting proteins and substrates, our understanding of the distinct in vivo functions of LNX1 and LNX2 remains very incomplete. …”
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Arterial hypertension: interrelation between heart, arterial and venous structure and function, their prognostic role in antihypertensive treatment optimization by A. V. Tuev, O. V. Khlynova, V. V. Shchekotov, A. V. Agafonov

“…The study included 184 patients with primary AH. CVS structure and function were assessed at baseline and after treatment with antihypertensive medications (AHM).Results. …”
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Characterization of Prejunctional Muscarinic Receptors: Effects on the Release of VIP and Functional Responses and Receptor Expression in the Ovine Submandibular Gland by Anders T. Ryberg, Ondrej Soukup, Gunnar Tobin

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Soluble Siglec-9 Improves Intestinal Barrier Function in a Mouse Model of Metabolic Dysfunction-Associated Steatohepatitis by Hisanori Muto, Fumitaka Mizuno, Takashi Honda, Shinya Yokoyama, Taku Tanaka, Kenta Yamamoto, Takanori Ito, Norihiro Imai, Yoji Ishizu, Kiyoshi Sakai, Hideharu Hibi, Masatoshi Ishigami, Hiroki Kawashima

“…<b>Conclusions</b>: sSiglec-9 may protect intestinal barrier function by mitigating mucosal inflammation. sSiglec-9 treatment may represent a novel therapeutic approach for MASH via gut–liver axis modulation.…”
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Cardiac function of colorectal cancer mice is remotely controlled by gut microbiota: regulating serum metabolites and myocardial cytokines by Zhan-Kui Gao, Chao-Yuan Fan, Bo-Wen Zhang, Jia-Xin Geng, Xing Han, Dan-Qi Xu, Muhammad Arshad, Hao-Xuan Sun, Jiong-Yi Li, Xiangyuan Jin, Xiao-Qin Mu

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Genomic diversity in functionally relevant genes modifies neurodevelopmental versus neoplastic risks in individuals with germline PTEN variants by Adriel Y. Kim, Lamis Yehia, Charis Eng

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Function analysis of LIPI-4 in Listeria monocytogenes reveals a key role of flagella formation in the regulation of virulence by Caixia Liu, Xun Ma, Bin Jia, Ruixuan Qian, Shengjie Gao, Lu Liu, Yatao Qi, Zhongke Yin, Guangdong Hu, Jing Wang

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From surface design to cellular Response: Insights into aryl-functionalized iron oxide nanoparticles with and without protein corona by Solange Mailen Selzer, Laura Vanesa Bonnet, María Belén Piccoli, Santiago Daniel Salas, Mauricio Galiano, Raquel Viviana Vico, Nancy Fabiana Ferreyra

“…The results demonstrate that surface functionalization significantly alters protein corona composition, which in turn modulates nanoparticle stability, cellular uptake, and biological responses. …”
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AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep by Hui Xu, Yu Cai, Hua Yang, Chong Zhang, Wanru Liu, Binru Zhao, Feng Wang, Yanli Zhang

“…These findings demonstrate AMH regulates GCs function through multiple pathways, offering insights into sheep fertility and potential targets to enhance reproductive efficiency.…”
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Candida albicans aspartyl protease (Sap6) inhibits neutrophil function via a “Trojan horse” mechanism by Marcin Zawrotniak, Dorota Satala, Magdalena Juszczak, Grażyna Bras, Maria Rapala-Kozik

“…This disruption in neutrophil functions by Sap6 suggested the presence of a ‘Trojan horse’ mechanism by C. albicans. …”
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Progress of the Target Selection and Localization of Repetitive Transcranial Magnetic Stimulation to Improve Upper Limb Function after Stroke by LIU Canhuan, SHEN Ying, DAI Wenjun, GUO Chuan, CHENG Yihui, ZHU Yi, WANG Tong

“…Currently, rehabilitation techniques for improving post-stroke upper limb motor function, both domestically and internationally, primarily involve motor function training.Repetitive transcranial magnetic stimulation (rTMS), because it can enhance upper limb motor function recovery by modulating cortical excitability and promoting neuroplasticity, has been increasingly used in stroke rehabilitation and has been included in the guideline as a grade A recommendation.However, there is still large heterogeneity in the relevant clinical studies, and the therapeutic effect is affected by factors such as different target selection and target localization accuracy. …”
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Layered Double Hydroxides as Systems for Capturing Small-Molecule Air Pollutants: A Density Functional Theory Study by Elaheh Mohebbi, Cristina Minnelli, Eleonora Pavoni, Laura Sisti, Emiliano Laudadio, Pierluigi Stipa

“…For this purpose, a Density Functional Theory (DFT) approach has been used to study the role of the elemental composition of LDHs, the type of counterion, and the ability of these systems to intercalate NO₂ and SO₂ between the LDH layers. …”
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