Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review by Marc Lecoultre, Valérie Dutoit, Paul R Walker

“…In addition, the engulfment of cancer cells affects TAM functionality, as apoptotic cell uptake (a process termed efferocytosis) promotes macrophage anti-inflammatory functions. …”
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Strigolactones mitigate drought stress in maize by improving chloroplast protection stomatal function and antioxidant defense mechanisms by Shakeel Ahmad, Tayyaba Zulfiqar, Haichang Yang, Muhammad Farooq

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Plant-Derived Exosomes: Carriers and Cargo of Natural Bioactive Compounds: Emerging Functions and Applications in Human Health by Sorur Yazdanpanah, Silvia Romano, Anna Valentino, Umberto Galderisi, Gianfranco Peluso, Anna Calarco

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The Molecular Landscape of Nitric Oxide in Ovarian Function and IVF Success: Bridging Redox Biology and Reproductive Outcomes by Diamandis Athanasiou, Charalampos Voros, Ntilay Soyhan, Georgia Panagou, Maria Sakellariou, Despoina Mavrogianni, Eleni Sivylla Bikouvaraki, George Daskalakis, Kalliopi Pappa

“…The stable metabolites nitrate (NO₃⁻) and nitrite (NO₂⁻) may indicate real-time follicular function during IVF. <b>Methods</b>: In this prospective study, we included 89 women who underwent controlled ovarian stimulation. …”
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Unraveling the role of shrimp hydrolysate as a food supplement in the immune function and fecal microbiota of beagle dogs by Joana Guilherme-Fernandes, Carolina Barroso, Alexandra Correia, Tiago Aires, Timur Yergaliyev, Amélia Camarinha-Silva, Manuel Vilanova, António J. M. Fonseca, Sofia A. C. Lima, Margarida R. G. Maia, Ana R. J. Cabrita

“…Abstract The inclusion of protein hydrolysates from animal by-products in petfood may enhance the industry’s sustainability, while contributing to dogs’ health due to their nutritional and functional properties. However, inconsistent results of protein hydrolysates on gut microbiota, immune responses, among other health parameters, have been observed in dogs. …”
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Multi-function composite data generation and PIMamba model for fault diagnosis in sucker-rod pumping wells by Senhao Ren, Wenqiang Tang, Chao Ma, Li Hou, Xiaodong Chen, Jiashan Lin, Jie Yang, Yun Yang, Xiao Huo, Guoxin Li, Daowei Zhang

“…To overcome these challenges, we propose a multi-function composite data generation paradigm that integrates diverse functional characteristics, generating 11 classes of highly interpretable single-condition images as training data for a prior model. …”
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Hindgut microbiota profiling and functional prediction of sheep (Ovis aries) fed with different dietary calcium levels by Muhammad Khan, Xiaoqi Zhao, Xiaojun Ni, Baiji Danzeng, Sikandar Ali, Maida Mushtaq, Hongyuan Yang, Jiachong Liang, Syed Khurram Fareed, Bai Xue, Guobo Quan

“…This study aimed to investigate the hindgut microbiota profile and functional prediction in sheep fed with different dietary calcium levels. …”
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Broccoli sprouts as an underrated functional food: a rich source of bioactive compounds with prominent anticancer properties by Kamila Smala, Julia Głowacz, Michał Popiel, Dominik Stanibuła, Kamil Dziekoński, Jakub Rybowski, Maksymilian Wiśniowski, Klaudia Kulig

“…Conclusions: Broccoli sprouts offer strong potential as a functional food in cancer prevention, thanks to their SFN content and multifaceted biological effects. …”
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MgATPase Activity is Dispensable for the Pharmacological Regulation of the Functional Effects of the KATP Channels Opening in Brain Mitochondria by Olga V. Akopova, Anton Smirnov

“…Background: The mechanisms underlying the effects of pharmacological mitochondrial ATP-sensitive K+ channel (mKATP) channel openers on the functional effects of the mKATP channels opening remain disputable. …”
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Digitoflavone Ameliorates Acute Lung Injury via Disturbing the Formation of Functional Stimulator of Interferon Genes Signalosome by Jun-Jie Li, Qing Yao, Ming Dong, Yan Wang, Ye Xiu, Zhi-Xin Wu, Xiao-Mei Zhao, Yin-Kang Wang, Xian-Ling Wang, Yu-Xuan Tian, Xiao-He Xiao, Zhao-Fang Bai

“…Thus, the search for modulators of the cGAS-STING signaling pathway is likely to contribute to their therapeutic prevention and treatment. …”
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Functional diversification of oxalate decarboxylases in terms of enzymatic activity, morphosporogenesis, stress regulation and virulence in Colletotrichum siamense by Yanyun Lv, Yu Liu, Yuqing Lin, Huiying Zheng, Jingting Yan, Yu Zhang, Weiguo Miao, Wei Wu, Chunhua Lin

“…However, the biological function of OxdCs in hemibiotropic fungi is still unknown. …”
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An Exploratory Analysis of Rhythmic Auditory Stimulation's Impact on Brain Function in Parkinson's Disease Patients With Freezing of Gait by Chen Liu, Miaomiao Hou, Shuili Yu, Ying Wan, Zhenguo Liu, Jing Gan

“…This study explored the impact of RAS on brain function in PD patients with FOG using functional near‐infrared spectroscopy (fNIRS) during an imagined walking task, with the aim of elucidating the underlying mechanisms involved. …”
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Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function by Longwei Sun, Junpeng Huang, Xiangyang Dou, Zhenyu Dong, Yuan Li, Shujing Tan, Ran Yu, Chengmin Li, Weiguo Zhao

“…Overall, these findings suggested that RES could alleviate NEFA-induced oxidative damage in BMECs by modulating mitochondrial function, thereby contributing to the prevention and treatment of oxidative damage in perinatal dairy cows with a negative energy balance.…”
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Dietary fatty acids promote gut health in weaned piglets by regulating gut microbiota and immune function by Zongze Fan, Lei Lei, Xingyue Wu, Ronghui Xing, Pengfei Du, Ziyang Wang, Huijuan Zhao, Yanqun Huang, Wen Chen, Xuemeng Si

“…Further study showed that the protective effect of MCFA and SCFA were associated with restoring gut barrier, upregulating abundances of Lactobacillus and Roseburia of piglets.InterpretationCollectively, the combination of MCFA and SCFA alleviated oxidative stress, modulated inflammation, and supported gut barrier function in weaned piglets, offering a promising alternative to ZnO, with VSM showing superior effects.…”
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Functional characterization of conserved small open reading frames on the genomic RNA of sonchus yellow net virus by Mengxin Gao, Shuang Ni, Yaqin Wang, Zhenghe Li, Pan Gong, Xueping Zhou, Fangfang Li

“…Using the ORF prediction software ViralORFfinder, we found that SYNV genomic RNA (gRNA) might contain small putative open reading frames (sORFs). However, the functions of these additional sORFs remain largely unexplored. …”
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Cadmium targeting transcription factor EB to inhibit autophagy-lysosome function contributes to acute kidney injury by Peng-Fei Dong, Tian-Bin Liu, Kai Chen, Dan Li, Yue Li, Cai-Yu Lian, Zhen-Yong Wang, Lin Wang

“…Objectives: Transcription factor EB (TFEB) is a critical transcription regulator that modulates autophagy-lysosome function, but its role in Cd-induced AKI is yet to be elucidated. …”
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Ultrasound Improves Gallbladder Contraction Function: A Non-Invasive Experimental Validation Using Small Animals by Run Guo, Tian Chen, Fan Ding, Li-Ping Liu, Fang Chen, Gang Zhao, Bo Zhang

“…Extended ultrasound exposure produced sustained functional improvements without tissue damage. Conclusions: Ultrasound effectively enhances gallbladder contractile function through mechanisms involving smooth muscle structural modification and calcium signaling modulation. …”
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Effects of functional antioxidants on the expansion of gamma delta T-cells and their cellular cytotoxicity against bladder cancer cells by Yueh Pan, Hung-Jen Shih, Shu-Han Chuang, Chin-Pao Chang, Chi-Hao Hsiao, Ya-Hsu Chiu, Pai-Fu Wang, Chi-Chen Lin, Ping-Hsiao Shih

“…However, oxidative stress also causes damage to cellular organelles. Thus, modulating ROS metabolism using antioxidants during naïve T-cell activation may promote the expansion and generation of functional T-cells. …”
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Functional characterization of SIZ1 homologs reveals reduced TSWV susceptibility of mutant Nicotiana benthamiana lines by Jelli Venkatesh, Seo-Young Lee, Ghimire Sunita, Jin-Kyung Kwon, Joung-Ho Lee, Byoung-Cheorl Kang

“…In conclusion, these observations indicate that SIZ1 negatively modulates the SA signaling pathway, and its loss of function can lead to increased immune responses, contributing to reduced disease susceptibility in plants. …”
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Impact of endoplasmic reticulum aminopeptidases 1 (ERAP1) and 2 (ERAP2) on neutrophil cellular functions by Irma Saulle, Irma Saulle, Fiona Limanaqi, Micaela Garziano, Micaela Garziano, Maria Luisa Murno, Valentina Artusa, Valentina Artusa, Sergio Strizzi, Matteo Giovarelli, Carsten Schulte, Jacopo Aiello, Mario Clerici, Mario Clerici, Claudia Vanetti, Mara Biasin

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