A deep learning-based detection model and illumination-adaptive behavioral analysis for soldier crabs in the intertidal zone by Liangjun Li, Zhihao Ren, Cheng Tang, Shengning Lu, Yong Liang

“…The model integrates an SPD-Conv module for efficient downsampling, a fine-grained channel attention mechanism for enhanced feature representation, and a robust SIoU loss function to improve the localization of small targets. …”
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MIF-YOLO: An Enhanced YOLO with Multi-Source Image Fusion for Autonomous Dead Chicken Detection by Jiapan Li, Yan Zhang, Yong Zhang, Hongwei Shi, Xianfang Song, Chao Peng

“…Additionally, an exponential moving average (EMA) attention mechanism is strategically embedded within the YOLO algorithm architecture's neck region to bolster the model's ability to discern targets under low-light scenarios, enhancing both its accuracy rates and adaptability. The loss function of the model is refined through the implementation of Modified Partial Distance-IoU (MPDIoU), facilitating a more nuanced evaluation of the overlap of objects. …”
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Dipeptides in CSF and plasma: diagnostic and therapeutic potential in neurological diseases by Katharina Küper, Gernot Poschet, Julia Rossmann, Sven F. Garbade, Alexander Spiegelhalter, Dan Wen, Georg F. Hoffmann, Claus P. Schmitt, Thomas Opladen, Verena Peters

“…Given the crucial role of AAs in central nervous system (CNS) function, this study investigated the presence of DPs in cerebrospinal fluid (CSF) and their correlation with corresponding AAs, potentially indicating their role as AA donors. …”
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Dynamic alterations of depressive-like behaviors, gut microbiome, and fecal metabolome in social defeat stress mice by Hongrui Li, Ping Liu, Tingfang Sun, Yifan Li, Jing Wu, Yu Huang, Jie Yang, Minghao Yuan, Jianping Zhang, Jian Yang, Ma-Li Wong, Julio Licinio, Peng Zheng

“…The microbial composition, function, and fecal metabolites exhibited distinct separations across the different social defeat stress groups. …”
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Protein interactions, network pharmacology, and machine learning work together to predict genes linked to mitochondrial dysfunction in hypertrophic cardiomyopathy by Jia-lin Chen, Di Xiao, Yi-jiang Liu, Zhan Wang, Zhi-huang Chen, Rui Li, Li Li, Rong-hai He, Shu-yan Jiang, Xin Chen, Lin-xi Xu, Feng-chun Lu, Jia-mao Wang, Zhong-gui Shan

“…We found a new target gene for HCM called CEBPD, which is probably going to function by mitochondrial dysfunction. An innovative aim for the management or avoidance of HCM is offered by this analysis. …”
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Modeling and Simulation of Automotive FMCW RADAR Sensor for Environmental Perception by Arsalan Haider, Abdulkadir Eryildirim, Marcell Pigniczki, Lukas Haas, Birgit Schlager, Thomas Zeh, David Nickel, Alexander W. Koch

“…The RADAR sensor model is developed using the standardized functional mock-up interface (FMI) and open simulation interface (OSI) and is integrated into the co-simulation environment of commercial software to demonstrate its exchangeability. …”
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Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer by Eleni Skourti, Kotryna Seip, Nadia Mensali, Shakila Jabeen, Siri Juell, Inger Øynebråten, Solveig Pettersen, Olav Engebraaten, Alexandre Corthay, Else Marit Inderberg, Helmut Dolznig, Gunhild Mari Mælandsmo, Eivind Valen Egeland, Lina Prasmickaite

“…How tumor cells that acquire resistance may subsequently modulate the immune microenvironment it is still not well described. …”
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Revealing the prognostic potential of natural killer cell-related genes in hepatocellular carcinoma: the key role of NRAS by Ruixi Li, Guangquan Zhang, Qiang Tao, Ziyun Wu, Xiaoping Liu, Rongrong Wang, Lei Liu, Yiran Niu, Kaile Du, Runpeng Wu, Fei Du, Xiyan Zheng, Yingliang Li, Xianjie Shi

“…In this study, we identified 24 differentially expressed NKCRGs in HCC specimens from the TCGA dataset, including 22 upregulated genes and 2 downregulated genes. Functional enrichment analysis revealed that these genes were mainly involved in immune response pathways and various cancer-related pathways. …”
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Photonics-Aided THz Integrated Sensing and Communication System Based on a Subcarrier-Chirp Inter-Embedded Waveform by Junhao Zhang, Mingzheng Lei, Min Zhu, Qingzhi Zhou, Bingchang Hua, Yuancheng Cai, Hao Li, Jiao Zhang, Zhengyi Liang, Yang Li, Xingyu Chen, Junjie Ding, Qing Zhong, Sha Zhu, Jianjun Yu

“…Here, we propose and experimentally demonstrate a photonics-assisted THz ISAC system based on a time-frequency efficient dual-function waveform. The key to designing the ISAC waveform is embedding the subcarrier communication signals in the idle time-frequency dimension of a linear frequency-modulated continuous wave (LFMCW). …”
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Perilla Seed Oil: A Review of Health Effects, Encapsulation Strategies and Applications in Food by Min Li, Nanjie Jiang, Guangqi Guo, Shuaijun Lu, Ziliang Li, Yujie Mu, Xiaoyang Xia, Zhenxia Xu, Yong Hu, Xia Xiang

“…Future investigations should also explore the synergistic effects of combining perilla seed oil with other functional components and its role in modulating gut microbiota to achieve comprehensive health benefits.…”
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USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma by Jiabing Li, Xiaorong Feng, Zhaohui Liu, Yunfang Deng, Zhiming Sun, Bei Chen, Lihui Wu, Xiaolong Wang, Lin Miao, Liyuan Zeng, Lei Hu, Yuming He, Ying Sheng, Yue Liu, Yu Zhao

“…USP7 binds directly to MGMT via its UBL domain, counteracts K48-linked ubiquitin chains, and prevents MGMT proteasomal degradation. This functional relationship is further supported by their nuclear colocalization. …”
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Physiological and transcriptomic-based analysis reveal the common and specific pathways of clove basil (Ocimum gratissimum) organs in response to cadmium stress by Bin Wang, Yanhui Xiao, Xiao Yuan, Yukun Wang, Dengyue Jiang, Zhaoxia Zhan, Jinming He

“…A total of 2,930, 594, and 2193 differentially expressed genes (DEGs) were identified in the roots, shoots, and leaves, respectively. Functional enrichment analysis revealed significant variations in the unique DEGs among each organ. …”
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Denervation of rectus capitis posterior minor as neglected factor in Chiari malformation type I revealed by double blinded prospective study by Yunsen He, Qinjiang Huang, Mingbin Bao, Mengjun Zhang, Xiaolin Hou, Ping Liu, Ye Tao, Hongliang Li, Kun Li, Li Liu, Lili Guo, Hao Wang, Zhou Zhang, Bo Wu

“…This study aims to explore RCPmi functionality in CMI patients compared to healthy controls using needle electromyography (nEMG). …”
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Discovery of an ApoE4-targeted small-molecule SirT1 enhancer for the treatment of Alzheimer’s disease by Jesus Campagna, Sujyoti Chandra, Bruce Teter, Whitaker Cohn, Johnny Pham, Young-Sug Kim, Barbara Jagodzinska, Kanagasabai Vadivel, Parvez Alam, Tina Bilousova, Malaney Young, Chris Elias, Juan Marcucci, Ilinca Flacau, Ainsley Jackman, Samar Padder, Dongwook Wi, Chunni Zhu, Patricia Spilman, Michael E Jung, Dale E Bredesen, Varghese John

“…DDL-218 treatment elicited improvement in memory in the AD model, suggesting that DDL-218 enhancement of neurotrophic SirT1 in the brain has potential to modulate neuronal activity that may clinically provide an improvement in cognitive function and complement the current anti-Aβ antibody monotherapy. …”
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Decoding the epigenetic-immune nexus in hepatocellular carcinoma: a Mendelian randomization study reveals BTN3A2, S100A12 and TRIM27 as white blood cell regulators by Yang Qiu, Haiyan Zhang, Xiao Yu, Jielu Pan, Dinghong Xiao, Hongyu Miao, Ruiqing Wang, Nan Shen, Peimin Pu, Yinling Zhou, Zhidong Liu, Lin He, Lianjun Xing

“…The robustness of our findings was established through stringent criteria, comprehensive sensitivity analyses, and Bayesian colocalization, followed by functional validation with TCGA data and a transcriptome-wide association study (TWAS). …”
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Melatonin Enhances the Low-Calcium Stress Tolerance by Regulating Brassinosteroids and Auxin Signals in Wax Gourd by Jingjing Chang, Xuemei Zhu, Yixuan Lian, Jing Li, Xiao Chen, Zhao Song, Lei Chen, Dasen Xie, Baige Zhang

“…Melatonin is a biologically active and multi-functional hormone that plays an important role in improving nutrient use efficiency. …”
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Small molecules direct the generation of ameloblast-like cells from human embryonic stem cells by Ximei Zhu, YiMeng Zhao, Xiaofan Bai, Qiannan Dong, Chunli Tian, Ruilin Sun, Congjuan Yan, Jianping Ruan, Zhongbo Liu, Jianghong Gao

“…Methods We developed a three-step strategy entailing the progression of hESCs through non-neural ectoderm (NNE) and DE to generate functional ameloblasts in vitro. Initially, the NNE fate was induced from hESCs using a 6-day differentiation protocol with 1 µmol/L Retinoic acid (RA). …”
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Transcriptome and DNA methylation analyses provide insight into the heterosis of growth-related traits in hybrid yellow croaker by Dan-Dan Guo, Feng Liu, Qing-Ping Xie, Ting Ye, Fu-Liang Wei, Bao-Long Niu, Bao Lou

“…A total of 1288 DMEGs were identified through correlation analysis between DNA methylation and transcriptional activity. Functional enrichment analysis revealed that most of the DMEGs were significantly enriched in pathways related to the protein export pathway, proteasome, terpenoid backbone biosynthesis, ubiquitin-mediated proteolysis, autophagy-other pathway. …”
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Modulatory role of Spirulina platensis in oxidative stress, apoptosis, and gene expression in a rat model of dexamethasone-induced hepatotoxicity by Amina Zedan, Amira M. El-Moslemany, Rasha M. Bahnasy, Hanan Salah Eldeen Eldamaty, Suzan S. Ibraheim, Badriyah S. Alotaibi, Mohamed Abdelmegeid, Mohamed Abdelmegeid, Mustafa Shukry, Ahmed A. Elolimy

“…The rising prevalence of hyperlipidemia and hepatic disorders has intensified interest in the therapeutic use of functional foods and botanical drugs. Spirulina platensis, a blue-green microalga, is known for its antioxidant, anti-inflammatory, and lipid-lowering properties. …”
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Dietary Supplementation of an Organic Acid-Based Feed Attractant in Juvenile Largemouth Bass (<i>Micropterus salmoides</i>): Effects on Growth, Morphohistology, and Oxidative Stres... by Guohe Cai, Zhizhong Li, Miao Yu, Mingya Huang, Pengao Liu, Xiudan Tang, Qizhe Huang, Zhixue Guo, Yunzhang Sun

“…These results suggest the attractant has practical value in improving fish welfare and nutrient utilization efficiency, providing a functional dietary strategy for sustainable largemouth bass farming.…”
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