Effects of <i>Tithonia diversifolia</i> Extract as a Feed Additive on Digestibility and Performance of Hair Lambs by Olga Teresa Barreto-Cruz, Juan Carlos Henao Zambrano, Maria Alejandra Ospina Barrero, Román David Castañeda-Serrano

“…The TDE were safe at 5 g and 10 g/day for liver function and exhibited lower BUN levels suggesting an improvement in protein metabolism. …”
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Stable microbial community promotes aerobic methanotrophy in a large river-reservoir system by Qiong Tang, Zhe Li, Lunhui Lu, Yan Xiao, Xinghua Wu, Dianchang Wang

“…In addition, the more pronounced niche differentiation also contributes to community stability in the lacustrine zone, which in turn facilitates the function of aerobic methanotrophy. In the riverine and lacustrine zones, the keystone species shift from the Alphaproteobacteria class (Alpha-MOB) to the Gammaproteobacteria class (Gamma-MOB), indicating distinct mechanisms for maintaining community stability in these zones. …”
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Triolein alleviates ischemic stroke brain injury by regulating autophagy and inflammation through the AKT/mTOR signaling pathway by Chaoqun Wang, Yuntao Li, Yonggang Zhang, Daniel Smerin, Lijuan Gu, Shuting Jiang, Xiaoxing Xiong

“…Methods We evaluated the impact of triolein using both in vitro oxygen-glucose deprivation/reoxygenation (OGD/R) and in vivo middle cerebral artery occlusion (MCAO/R) models. Neurological function and cerebral infarct volume were assessed 72 h post-reperfusion. …”
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SREBF1 mediates immunoparalysis of dendritic cells in sepsis by regulating lipid metabolism and endoplasmic reticulum stress by Yaolu Zhang, Fangfang Wu, Yan Li, Jiaxin Liu, Liuyan Zhu, Min Zhang, Zhongqiu Lu

“…SREBF1 silencing attenuated the lipid-induced ER stress and restored DC function, whereas tunicamycin treatment partially reversed these protective effects. …”
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miR-379-5p affects breast cancer cell behavior by targeting UBE2E3 ubiquitin conjugating enzyme. by Araya K Schroder, Conor J Loy, Fernanda Aiala, Jazmyn Rafique, Arnob Ghosh, Lina I Yoo

“…MicroRNAs (miRNAs) play an increasingly recognized role in modulating cancer development. Due to their function in regulating gene expression, miRNAs can suppress or promote tumorigenesis. miR-379-5p expression is downregulated in multiple human cancers, including breast and bladder cancers. …”
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The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…Results: The results showed that JQ1 administration reduces fat mass, preserving skeletal muscle mass and function. A direct JQ1 lipolytic effect was demonstrated on mature adipocyte cultures. …”
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Association between ultra-short-term heart rate variability and atrial fibrillation in heart failure population: a protocol for a prospective observational cohort study by Ping Zhang, Xiaodi Tang, Rong He

“…Introduction Patients with heart failure with reduced ejection fraction (HFrEF) and heart failure with mildly reduced ejection fraction (HFmrEF) are at high risk for developing atrial fibrillation (AF) due to significantly impaired cardiac pump function, heightened sympathetic nervous system activity and the frequent coexistence of cardiovascular comorbidities such as hypertension and coronary artery disease. …”
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Wheatgrass ameliorates glycerol-induced nephrotoxicity via regulation of NF-kB p65/KIM-1/NGAL signaling pathway by Nahed A. Raslan, Hend Helal, Amany Balah, Ahmed M. El-Dessouki, Azza A. Ali

“…WG was administered daily at 75 mg/kg for 7 days prior to glycerol administration in the WG-pretreated groups. Renal function, OS, inflammatory, and tubular injury markers were assessed using Enzyme-Linked Immunosorbent Assay. …”
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Microbial diversification is maintained in an experimentally evolved synthetic community by Zahraa Al-Tameemi, Alejandra Rodríguez-Verdugo

“…We further observed loss-of-function mutations in flagellar genes that were fixed in monocultures but not in co-cultures. …”
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The ArcAB two-component system is associated with the susceptibility of Aggregatibacter actinomycetemcomitans to superoxide and hydrogen peroxide by Mohammad Farid Ratman, Yuichi Oogai, Airi Matsumoto, Masanobu Nakata

“…It is also known to provide adaptation to ROS stress; however, its function in A. actinomycetemcomitans remains unclear. …”
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WRKY11 up-regulated dirigent expression to enhance lignin/lignans accumulation in Lilium regale Wilson during response to Fusarium wilt by Jie Deng, Zi’e Wang, Wenyun Li, Xiaohua Chen, Diqiu Liu

“…In this study, a WRKY transcription factor, WRKY11, was isolated from L. regale, and its function during the interaction between L. regale and F. oxysporum was characterized. …”
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Systematic review and meta-analysis of microbiota-gut-astrocyte axis perturbation in neurodegeneration, brain injury, and mood disorders by Daniel E. Radford-Smith, Katharine Oke, Carolina F.F.A. Costa, Daniel C. Anthony

“…Future studies must adopt new, multi-dimensional studies of astrocyte function and dysfunction, to elucidate their role in disease and explore the therapeutic potential of gut microbiota modulation.…”
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Lactiplantibacillus plantarum IOB602 Postbiotic Ameliorates Depression-like Behaviors by Regulating Neuroendocrine Factors and Gut Microbiota in Mice by JING Zhaoxuan, LIANG Peixin, HAN Xuemei, ZHANG Yihua, DENG Langni, JIA Longgang, WANG Yanping, GENG Weitao

“…Finally, 16S rDNA sequencing was utilized to analyze gut microbiota composition, gas chromatography (GC) was used to measure short-chain fatty acids (SCFAs), and hematoxylin-eosin (H&E) staining and immunofluorescence techniques were employed to assess the function of the intestinal barrier. The results showed that postbiotic LP602 significantly increased the sucrose preference of CUMS mice and the time spent in the central area, while significantly reducing the immobility time in the forced swimming test (FST) and the tail suspension test (TST). …”
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Optimization Design and Test Analysis of Rice Electric Binder Knotter Based on ADAMS by Difa Bao, Jufei Wang, Zhi Liang, Chongcheng Chen, Wuxiong Weng, Shuhe Zheng, Jinbo Ren

“…The knotter, as a core module for the knotting function of a rice electric binder, has structural parameters and spatial configurations that significantly impact the efficiency and quality of rice collection, making the in-depth analysis and optimization of these parameters, and their spatial relationships, crucial for enhancing the operational quality of the rice electric binder. …”
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Unravelling the Erythropoietin Heterodimeric Complex: In Silico Analysis of Complex Assembly and Binding Interface by Atiya Habib, Urooj Qureshi, Mohammad Nur-e-Alam, Aftab Ahmed, Zaheer Ul-Haq

“…This function of Epo is linked with its heterodimeric form, i.e. …”
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A novel lightweight YOLOv8-PSS model for obstacle detection on the path of unmanned agricultural vehicles by Zhijian Chen, Yijun Fang, Jianjun Yin, Shiyu Lv, Farhan Sheikh Muhammad, Lu Liu

“…After optimization, the bounding box loss function is finally upgraded to Shape-IoU (Shape Intersection over Union), which improves both model accuracy and generalization.ResultsThe experimental results demonstrate that the improved YOLOv8_PSS model achieves a precision of 85.3%, a recall of 88.4%, and an average accuracy of 90.6%. …”
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Ray Visualization and Through-Focus Optical Quality of Diffractive Enhanced Monofocal and Extended-Depth-of-Focus Intraocular Lenses by Baur ID, Khoramnia R, Son HS, Auffarth GU, Łabuz G

“…Isabella Diana Baur,1,2 Ramin Khoramnia,1 Hyeck-Soo Son,1 Gerd Uwe Auffarth,1 Grzegorz &amp;Lstrok;abuz1 1David J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany; 2Augsburg University Hospital, Department of Ophthalmology, Augsburg, GermanyCorrespondence: Isabella Diana Baur, Augsburg University Hospital, Department of Ophthalmology, Stenglinstraße 2, Augsburg, 86156, Germany, Email Isabella.Baur@uk-augsburg.dePurpose: We compared two hybrid refractive-diffractive IOLs with enhanced depth of focus in an in vitro study with regard to optical quality in monochromatic and polychromatic light as well as their ray-propagation behavior.Methods: The Mono-EDoF ME4 IOL (Santen Pharmaceutical, Osaka, Japan) and the Tecnis Symfony IOL (Johnson &amp; Johnson Vision, USA) were assessed using the OptiSpheric IOL PRO 2 (Trioptics GmbH, Germany) to measure the through focus (TF) modulation transfer function (MTF) using monochromatic green (546 nm) and polychromatic light at different spatial frequencies. …”
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Long-term effects of a double hit murine model for schizophrenia on parvalbumin expressing cells and plasticity-related molecules in the thalamic reticular nucleus and the habenula by Patrycja Klimczak, Julia Alcaide, Yaiza Gramuntell, Esther Castillo-Gómez, Emilio Varea, Marta Perez-Rando, Juan Nacher

“…Plasticity molecules associated to inhibitory neurons, such as PSA-NCAM, or NMDA receptors (NMDAR) can also influence the structure and function of these cells. Growing evidence also indicates that glial cells regulate the physiology of PV+ neurons by influencing their maturation and modulating their synaptic connectivity. …”
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GINS1 facilitates the development of lung adenocarcinoma via Wnt/β-catenin activation by Luyuan Ma, Rongyang Li, Pengyong Li, Wenhao Yu, Zhanpeng Tang, Libo Si, Hui Tian

“…GINS1 has a significant regulatory function in DNA replication. It is overexpressed in various malignant tumors, but the specific molecular mechanisms of GINS1 in LUAD pathogenesis are not fully elucidated. …”
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Application of an improved ant colony algorithm based on unevenly distributed pheromone and multi-objective optimization in path planning for unmanned surface vehicles by Guobing XIE, Wei HE, Wangwen HU, Yixin Su, Binghua SHI

“…Meanwhile, to optimize efficiency improvement, an adaptive adjustment strategy of heuristic matrix coefficient is established, incorporating cosine modulation factors pertaining to iteration numbers. …”
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