Ion Intercalation‐Mediated MoS2 Conductance Switching for Highly Energy‐Efficient Memristor Synapse by Bin Zhao, Xuan Zhao, Xiaochen Xun, Fangfang Gao, Qi Li, Jiayi Sun, Tian Ouyang, Qingliang Liao, Yue Zhang

“…Here, ion intercalation‐mediated conductance switching in MoS2 is introduced for a highly energy‐efficient memristor synapse (HEMS) to accurately emulate the bio‐synaptic function. Li‐ion intercalation into the few‐layer MoS2 can induce structural evolution, thereby achieving high‐speed and controllable conductance modulation in HEMS. …”
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Integrative multi-omics analysis reveals the LncRNA 60967.1–PLCD4–ATRA axis as a key regulator of colorectal cancer progression and immune response by Yiyi Chen, Ningning Zhao, Lingna Xu, Xiya Jia, Fang Liu, Jian Huang, Xuhua Li, Yunfei Wang, Chuanxi Lai, Yanbin Shen, Fei Wang, Yiming Lv, Xuefeng Huang, Fan Zhang, Hongcang Gu, Sheng Dai

“…A significant interaction network comprising 22 lncRNAs, 14 mRNAs/proteins, and 9 metabolites was identified, among which lncRNA 60967.1 emerged as a pivotal regulator. Functional validation demonstrated that lncRNA 60967.1 is markedly downregulated in CRC cell lines and patient tissues. …”
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Acute gabapentin administration in healthy adults. A double-blind placebo-controlled study using transcranial magnetic stimulation and 7T 1H-MRS by Katherine Dyke, Sophia E. Pépés, Ben Babourina-Brooks, Chen Chen, Soyoung Kim, Hilmar P. Sigurdsson, Amelia Draper, Masud Husain, Parashkev Nachev, Penny Gowland, Peter G. Morris, Stephen R. Jackson

“…These findings have implications for the use of acute GBP dosing as a means to explore GABAergic function in health and disease.…”
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Oxytocin Protects PC12 Cells Against β-Amyloid-Induced Cell Injury by Mohammed Mufadhe Alanazi, Awatif B. Albaker, Lamia A. Alzaagi, Jawza F. Alsabhan, Fawaz Alasmari, Mohammed M. Almutairi, Metab S. Alharbi, Abdullah F. Alasmari, Faleh Alqahtani, Sary Alsanea

“…In this study, we aim to assess oxytocin’s protective effects on cell viability, oxidative stress, mitochondrial function, and apoptotic signaling. <b>Methods</b>: PC12 cells were treated with Aβ25–35 and pre-treated with varying oxytocin concentrations to assess cell viability, reactive oxygen species (ROS) generation, and mitochondrial membrane potential. …”
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Ta-YOLO: overcoming target blocked challenges in greenhouse tomato detection and counting by Yun Zhao, Yijia Chen, Xing Xu, Yong He, Hao Gan, Na Wu, Zhechen Wang, Xi Sun, Yali Wang, Petr Skobelev, Yanan Mi

“…Finally, we proposed the EWDIoU bounding box loss function, which leveraged a 2D Gaussian distribution to enhance the model’s accuracy and robustness. …”
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Spatiospectral dynamics of electroencephalography patterns during propofol-induced alterations of consciousness states by Xuan Li, Dezhao Liu, Zheng Li, Rui Wang, Xiaoli Li, Tianyi Zhou

“…We present an alpha modulation index which characterizes how these patterns track the transition from awake to sedation as a function of increasing dosage. …”
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Polysaccharide of Atractylodes macrocephala Koidz alleviate LPS-induced inflammatory liver injury by reducing pyroptosis of macrophage via regulating LncRNA GAS5/miR-223-3p/NLRP3 a... by Xiaoxiao Chen, Shuzhan Yang, Xin Long, Wanyan Li, Bingxin Li, Cheng Fu, Caoxue Zhen, Danning Xu, Xinliang Fu, Nan Cao

“…In RAW264.7 macrophages, dual-luciferase assays validated ceRNA interactions, while gain/loss-of-function experiments elucidated molecular mechanisms.ResultsIn this study, we found that PAMK alleviated LPS-induced inflammatory liver injury in mice and modulates macrophage pyroptosis through the lncRNA GAS5/miR-223/NLRP3 axis.ConclusionWe conclude that there is a ceRNA relationship between GAS5, miR-223-3p, and NLRP3; PAMK alleviates LPS-induced pyroptosis in macrophages through the lncRNA GAS5/miR-223-3p/NLRP3 axis; and PAMK intervention in the macrophage pyroptosis process subsequently alleviates liver inflammation.…”
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A biochemical screening platform to target chromatin states using condensates as a tool by Laura J. Hsieh, Tracy Lou, Muryam A. Gourdet, Emily Wong, Geeta J. Narlikar

“…Substantial previous work has indicated that the function of a given chromatin state is encoded in the context-dependent protein-protein interactions (PPIs) between the Intrinsically disordered regions (IDRs) and folded domains of the multiple constituents. …”
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High-throughput end-to-end aphid honeydew excretion behavior recognition method based on rapid adaptive motion-feature fusion by Zhongqiang Song, Jiahao Shen, Qiaoyi Liu, Wanyue Zhang, Ziqian Ren, Kaiwen Yang, Xinle Li, Jialei Liu, Fengming Yan, Wenqiang Li, Yuqing Xing, Lili Wu

“…Simultaneously, the RT-DETR detection model underwent deep optimization: a spline-based adaptive nonlinear activation function was introduced, and the Kolmogorov-Arnold network was integrated into the deep feature stage of the ResNet50 backbone network to form the RK50 module. …”
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Proteome of granulosa cells lipid droplets reveals mechanisms regulating lipid metabolism at hierarchical and pre-hierarchical follicle in goose by Xin Yuan, Xi Zhang, Yueyue Lin, Hengli Xie, Zhujun Wang, Xinyue Hu, Shenqiang Hu, Liang Li, Hehe Liu, Hua He, Chunchun Han, Xiang Gan, Ling Liao, Lu Xia, Jiwei Hu, Jiwen Wang

“…Following this, the potential functions of these DEPs were investigated through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis. …”
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Acupuncture regulates astrocyte neurotoxic polarization to protect blood–brain barrier integrity in delayed thrombolysis through mediating ERK1/2/Cx43 axis by Zhi-Hui Zhang, Yu Gu, Zheng Huang, Xin-Yu Liu, Wen-Tao Xu, Xin-Chang Zhang, Guang-Xia Ni

“…Results: Acupuncture reduced infarct volume, improved neurological function, and restored BBB integrity. Transcriptomic analysis revealed dynamic regulation of astrocyte neurotoxic polarization following acupuncture intervention. …”
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Viterbi-Viterbi Carrier Phase Estimation for Multi-Ring <inline-formula><tex-math notation="LaTeX">$M$</tex-math></inline-formula>-APSK With Wiener Carrier Phase Noise and Its Perf... by Qian Wang, Wenqiang Ma, Li Ping Qian, Xinwei Du, Changyuan Yu, Pooi-Yuen Kam

“…High-order modulations are currently widely used in optical communications to increase the data rate. …”
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Cosmetic Potential of <i>Haberlea rhodopensis</i> Extracts and Extracellular Vesicles in Human Fibroblast Cells by Milena Georgieva, Bela Vasileva, Penyo Ivanov, Kamelia Hristova-Panusheva, Tsvetelina Paunova-Krasteva, Ivan Lesov, Zlatina Gospodinova, Natalia Krasteva, George Miloshev, Vasil Georgiev

“…Emerging evidence suggests that plant-derived bioactive compounds and extracellular vesicles (EVs) play a crucial role in modulating cellular homeostasis, promoting tissue regeneration, and counteracting age-related morphological and functional changes. …”
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Probiotic <i>Lactobacillus johnsonii</i> Reduces Intestinal Inflammation and Rebalances Splenic Treg/Th17 Responses in Dextran Sulfate Sodium-Induced Colitis by Hao-Yu Liu, Shicheng Li, Kennedy Jerry Ogamune, Peng Yuan, Xinyu Shi, Wael Ennab, Abdelkareem A. Ahmed, In Ho Kim, Ping Hu, Demin Cai

“…Inflammatory bowel disease (IBD), a chronic inflammatory disorder of the gastrointestinal tract, is frequently complicated by extraintestinal manifestations such as functional hyposplenism. Increasing evidence highlights its pathogenesis as a multifactorial interplay of gut dysbiosis, intestinal barrier dysfunction, and dysregulated immune responses. …”
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Leukocyte-Rich Platelet-Rich Plasma’s Clinical Effectiveness in Arthroscopic Rotator Cuff Repair: A Meta-Analysis of Randomized Controlled Trials by Peiyuan Tang, Meihui Huang, Wenfeng Xiao, Ting Wen, Pavel Volotovsky, Mikhail Gerasimenko, Shiyao Chu, Shuguang Liu, Kai Zhang, Yusheng Li

“…<b>Conclusions</b>: Based on current evidence, the use of LR-PRP in arthroscopic rotator cuff repair could lessen postoperative pain and improve postoperative functional scores in individuals with rotator cuff injuries.…”
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Effects of Dietary Additives on Nitrogen Balance, Odor Emissions, and Yolk Corticosterone in Laying Hens Fed Low-Protein Diets by Ju-Yong Song, Yun-Ji Heo, Jina Park, Hyun-Kwan Lee, Yoo Bhin Kim, Byung-Yeon Kwon, Da-Hye Kim, Kyung-Woo Lee

“…Four commercially available functional feed additives (<i>Bacillus subtilis</i>, protease, saponin, and thyme-based essential oil) were selected for this study. …”
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Comparative transcriptomic and genomic analysis of tumor cells in the marginal and center regions of tumor nests in human hepatocellular carcinoma by Ziyi Li, Ziyi Li, Yikai Hu, Yikai Hu, Zhuotian He, Heyi Xu, Hongyang Wang, Hongyang Wang, Hongyang Wang, Yufei He

“…This center-margin functional division may inform rational design of therapeutics that simultaneously modulate metabolism and immune responses.…”
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Comparative genomic analysis of ten Elizabethkingia anophelis isolated from clinical patients in China by Fei Wu, Yan Wu, Miaomiao Zhang, Lijun Tian, Xue Li, Xi Luo, Yiquan Zhang, Renfei Lu

“…The virulence factors (VFs) in the 10 strains were classified into 13 functional categories, and the differences between strains were mainly in immune modulation and nutritional/metabolic factor. …”
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Identification and validation of key genes associated with cell senescence in acute myocardial infarction by Weidong Zhao, Guofu Zhu, Tianshu Chu, Liyong Wu, Hui Li, Qingwen Zhen, Rigui Wang

“…Besides, the expression of key genes were validated by quantitative real-time polymerase chain reaction (qRT-PCR).ResultsScreening for two key genes (ATP6V0B and DYNLL1) from 914 DEGs, and they were involved in functional pathways such as ‘mast cell activation’, ‘cytosolic ribosome’. …”
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Indirect improvement of pepino (Solanum muricatum) productivity via nitrogen fertilizer-mediated microbial and enzymatic stimulation by Bingbing Su, Bingbing Su, Huaidi Pei, Shiweng Li, Zhongming Ma, Yuliang Chen, Yubin Li, Liguang Wang, Minmin Zhang, Zhongwang Li

“…Moreover, the PLS analysis illustrated that nitrogen fertilization indirectly enhanced pepino productivity by stimulating urease and nitrate reductase activities, and enriching functional microbiota (Nitrosomonas, Opitutus, Ensifer, and Mesorhizobium) to facilitate soil nutrient mobilization (soil total nitrogen, available nitrogen and available potassium) for plant growth. …”
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