Research on Abnormal Ship Brightness Temperature Detection Based on Infrared Image Edge-Enhanced Segmentation Network by Xiaobin Hong, Guanqiao Chen, Yuanming Chen, Ruimou Cai

“…Finally, a specialized loss function with edge weights supervises the fusion features. …”
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Huanglian Jiedu Decoction Treats Ischemic Stroke by Regulating Pyroptosis: Insights from Multi-Omics and Drug–Target Relationship Analysis by Yixiao Gu, Zijin Sun, Tao Li, Xia Ding

“…<b>Results:</b> HLJD effectively mitigated IS-related damage, maintaining neurological function, reducing ischemic levels, protecting cellular morphology, inhibiting neuronal apoptosis, and preserving blood–brain barrier integrity. …”
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GAD2 on chromosome 10p12 is a candidate gene for human obesity. by Philippe Boutin, Christian Dina, Francis Vasseur, Séverine Dubois, Laetitia Corset, Karin Séron, Lynn Bekris, Janice Cabellon, Bernadette Neve, Valérie Vasseur-Delannoy, Mohamed Chikri, M Aline Charles, Karine Clement, Ake Lernmark, Philippe Froguel

“…SNP +83897 T>A was associated with lower fasting insulin and insulin secretion, as assessed by the HOMA-B% homeostasis model of beta-cell function (p = 0.009 and 0.01, respectively). These data support the hypothesis of the orexigenic effect of GABA in humans and of a contribution of genes involved in GABA metabolism in the modulation of food intake and in the development of morbid obesity.…”
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Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS. by Yunpeng Wang, Wesley K Thompson, Andrew J Schork, Dominic Holland, Chi-Hua Chen, Francesco Bettella, Rahul S Desikan, Wen Li, Aree Witoelar, Verena Zuber, Anna Devor, Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, Enhancing Neuro Imaging Genetics through Meta Analysis Consortium, Markus M Nöthen, Marcella Rietschel, Qiang Chen, Thomas Werge, Sven Cichon, Daniel R Weinberger, Srdjan Djurovic, Michael O'Donovan, Peter M Visscher, Ole A Andreassen, Anders M Dale

“…For each stratum of these relative enrichment scores, we obtain nonparametric estimates of posterior expected test statistics and replication probabilities as a function of discovery z-scores, using a resampling-based approach that repeatedly and randomly partitions meta-analysis sub-studies into training and replication samples. …”
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Natural and vaccine-mediated immunity to Salmonella Typhimurium is impaired by the helminth Nippostrongylus brasiliensis. by Saeeda Bobat, Matthew Darby, Dunja Mrdjen, Charlotte Cook, Erin Logan, Jennifer Auret, Elizabeth Jones, Elizabeth Jones, Corinna Schnoeller, Adriana Flores-Langarica, Ewan A Ross, Alykhan Vira, Constantino López-Macías, Constantino López-Macías, Ian R Henderson, James Alexander, Frank Brombacher, William G Horsnell, Adam F Cunningham

“…<h4>Background</h4>The impact of exposure to multiple pathogens concurrently or consecutively on immune function is unclear. Here, immune responses induced by combinations of the bacterium Salmonella Typhimurium (STm) and the helminth Nippostrongylus brasiliensis (Nb), which causes a murine hookworm infection and an experimental porin protein vaccine against STm, were examined.…”
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EMPIRICAL ASPECTS OF THE INFLUENCE OF THE COOPERATION OF FISCAL INSTITUTIONS ON PROPERTY TAX ADMINISTRATION by Oksana Desyatnyuk, Andriy Krysovatyy, Bohdana Shuliuk, Fedir Tkachyk, Vadym Maslii

“…Theoretical and methodical approaches to forecasting property tax revenues to local budgets of Ukraine have been further developed, taking into account fiscal policy trends under martial law and using the «forecasting» module of the SPSS statistics package. This approach made it possible to identify the limited fiscal impact of the real estate tax (excluding land), which does not align with global practices and indicates the incomplete fiscal and regulatory function of this tax in Ukraine. …”
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Identification of Resistance Loci to Avian Leukosis via Genome-Wide Association Analysis in Chengkou Mountain Chickens by Yuhang Li, Min Tan, Guang Yang, Qinwen Xu, Qigui Wang, Haiwei Wang, Xi Lan

“…This study is the first to identify ALV-J resistance-associated genetic markers in Chengkou mountain chickens, revealing key genes related to immune regulation, membrane function, and tumor development. The findings provide a foundational molecular basis for disease-resistant breeding in poultry.…”
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Temporal changes in ruminal microbiota composition and diversity in dairy cows supplemented with a lactobacilli-based DFM by Bronwyn E. Campbell, Mohammad Mahmudul Hassan, Robert J. Moore, Timothy Olchowy, Martin Soust, Rafat Al Jassim, John I. Alawneh, John I. Alawneh

“…The observed microbial shifts, including increases in beneficial bacterial taxa, highlight the potential of DFM as a nutritional strategy to modulate rumen function and improve dairy cow performance.…”
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Unveiling the Genomic Landscape of <i>Pseudorasbora parva</i>, the Most Invasive Freshwater Fish Worldwide: A Key Step Towards Understanding Invasion Dynamics by Marine Combe, Théo Deremarque, Justina Givens, Rodolphe Elie Gozlan

“…We identify candidate loci linked to immune function and provide insights into the evolutionary dynamics of co-introduction. …”
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Smoke and Fire-You Only Look Once: A Lightweight Deep Learning Model for Video Smoke and Flame Detection in Natural Scenes by Chenmeng Zhao, Like Zhao, Ka Zhang, Yinghua Ren, Hui Chen, Yehua Sheng

“…Then, a two-channel loss function (W-SIoU) based on dynamic tuning and intelligent focusing is designed to enhance loss computation in the boundary regions, thus improving the YOLOv11 model’s ability to recognize targets with ambiguous boundaries. …”
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Physical activity and health-related quality of life after lung cancer surgery– cross-sectional analyses 3 and 12 months postoperatively by Marcus Jonsson, Anita Hurtig-Wennlöf, Anders Ahlsson, Elisabeth Westerdahl

“…Patients who reached the recommended level of physical activity reported a better HRQoL, with better global health status and physical function as well as lower symptoms of fatigue, at both 3 and 12 months postoperatively. …”
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Enhanced Efficiency in SMEs Attendance Monitoring: Low Cost Artificial Intelligence Facial Recognition Mobile Application by Hong-Danh Thai, Yeong-Seok Seo, Jun-Ho Huh

“…Employees&#x2019; facial identities using the Resnet34 model integrated Additive Angular Margin Loss function to identify employees&#x2019; facial identities. …”
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DMF-YOLO: Dynamic Multi-Scale Feature Fusion Network-Driven Small Target Detection in UAV Aerial Images by Xiaojia Yan, Shiyan Sun, Huimin Zhu, Qingping Hu, Wenjian Ying, Yinglei Li

“…Finally, we propose an Expanded Window-based Bounding Box Regression Loss Function (EW-BBRLF), which optimizes localization accuracy through dynamic auxiliary bounding boxes, effectively reducing missed detections of small targets. …”
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Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. by Michael A Siuta, Sabrina D Robertson, Heidi Kocalis, Christine Saunders, Paul J Gresch, Vivek Khatri, Chiyo Shiota, J Philip Kennedy, Craig W Lindsley, Lynette C Daws, Daniel B Polley, Jeremy Veenstra-Vanderweele, Gregg D Stanwood, Mark A Magnuson, Kevin D Niswender, Aurelio Galli

“…Thus, we propose that amplified NET function in rictor KO mice enhances accumulation of both NE and DA within the noradrenergic neuron. …”
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The role of cyclic di-GMP in biomaterial-associated infections caused by commensal Escherichia coli. by Shanshan Li, Chengwei Bi, Bingquan Xiang, Zhonghui Wang, Hui Yang, Chaojiang Fu, Lianpu Chen, Ying Chen

“…The results also reiterate the canonical function of c-di-GMP, which is to reduce the motility of bacteria. …”
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A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10. by Jacopo Lucchetti, Marianna Marino, Simonetta Papa, Massimo Tortarolo, Giovanna Guiso, Silvia Pozzi, Valentina Bonetto, Silvio Caccia, Ettore Beghi, Caterina Bendotti, Marco Gobbi

“…Recently, the coenzyme-Q (CoQ) complex, a key component of mitochondrial function and redox-state modulator, has raised interest for ALS treatment. …”
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Safety and efficacy of remimazolam in mechanical ventilation in the ICU: a protocol for systematic evaluation and meta-analysis by Li Liu, Xuelian Yang, Yulian Yang, Gelan Miao, Chaobing Yang, Xianying Lei

“…Intensive care unit (ICU) patients frequently exhibit impaired liver and renal function as well as haemodynamic instability; thus, the pharmacokinetic properties of remimazolam may offer advantages for ICU sedation. …”
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Inflammation and cancer cell survival: TRAF2 as a key player by Adriana Albini, Luisa Di Paola, Giampiero Mei, Denisa Baci, Nicola Fusco, Giovanni Corso, Douglas Noonan

“…In the adaptive immune system, it represses effector B- and T-cell activity while sustaining regulatory T-cell function, thus promoting immune suppression. The lack of fine-tuning of TRAF2 activity leads to excessive NF-kB activation, driving chronic inflammation and autoimmunity. …”
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Exploring the anticonvulsant potential of Daucus carota L.: A combined in silico and in vivo study for epilepsy therapy development by Naznin Sarkar, Anil Kumar Venkategowda Kodihally, Akshay Shamnewadi

“…Conclusion: These findings suggest that phytoconstituents from Daucus carota L. possess significant therapeutic potential as adjunctive treatments for epilepsy through the modulation of GABAergic activity and calcium channel function. …”
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Variants of active assist robotic therapy: feasibility of virtual assistance and proprioceptive training as gauged by their effects on success and motivation during finger movement... by Andria J. Farrens, Dylan Reinsdorf, Luis Garcia-Fernandez, Raymond Diaz Rojas, Vicky Chan, Joel Perry, Eric T. Wolbrecht, David J. Reinkensmeyer

“…Baseline proprioceptive and motor function were assessed prior to training, and motivation for training was assessed using the Intrinsic Motivation Inventory. …”
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