Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy by Bo Huang, Bo Huang, Qihang Yuan, Jiaao Sun, Chao Wang, Dong Yang

“…Recent research has increasingly illuminated the diverse functions of TYMP. It is known to facilitate platelet activation, osteoclast differentiation, and angiogenesis. …”
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Effects of a single tDCS with mirror therapy stimulation on hand function in healthy individuals by Małgorzata Wójcik, Přemysl Vlček, Přemysl Vlček, Idzi Siatkowski, Marcela Grünerová-Lippertová, Marcela Grünerová-Lippertová

“…IntroductionTranscranial direct current stimulation (tDCS) is a non-invasive neuromodulatory technique that has garnered significant interest for its ability to modulate cortical excitability and brain function. …”
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allograft inflammatory factor 1 functions as a pro-inflammatory cytokine in the oyster, Crassostrea ariakensis. by Ting Xu, Jiasong Xie, Baojian Zhu, Xiao Liu, Xinzhong Wu

“…Therefore we investigated the functions of C. ariakensis AIF-1 (Ca-AIF1) and its antibody (anti-CaAIF1) in oyster RLO/LPS-induced disease and inflammation. …”
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The Spatial‐Temporal Alternative Splicing Profile Reveals the Functional Diversity of FXR1 Isoforms in Myogenesis by Wei Wang, Xinhao Fan, Weiwei Liu, Yuxin Huang, Shuhong Zhao, Yalan Yang, Zhonglin Tang

“…Collectively, these findings provide a comprehensive resource for AS studies in skeletal muscle development, underscoring the diverse functions and regulatory mechanisms governing distinct Fxr1 isoforms in myogenesis.…”
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Structural and functional insights of ZnT1 C-terminal domain as a regulator of zinc transport by Tomer Eli Ben Yosef, Itamar Kass, Anat Shahar, Ekaterina Eremenko, Alon Monsonego, Daniel Gitler, Arie Moran, Raz Zarivach

“…Abstract Zinc is an essential trace element vital for cellular function, and its homeostasis is tightly regulated. …”
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BMSCs-targeting piezoelectric stimulation and immunomodulatory dual-functional hydrogel for promoting diabetic bone regeneration by Jintao Dong, Wengang Dong, Huijie Ran, Dongxu Wu, Xinli Wang, Hongli Chen, Jiahao Cao, Xu Wang, Xinsen Lin, Wei Lei, Tianji Wang, Yafei Feng

“…This resulted in a dual-functional B-TNs@CMS composite hydrogel designed to combine targeted BMSC stimulation with immunomodulatory properties. …”
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Direct detection with an optimal transfer function: toward the electrical spectral efficiency of coherent homodyne detection by Xingfeng Li, Jingchi Li, Xiong Ni, Hudi Liu, Qunbi Zhuge, Haoshuo Chen, William Shieh, Yikai Su

“…This study derives the optimal DD receiver structure with an optimal transfer function to recover a quadrature amplitude modulation (QAM) signal with a near-zero guard band at the central frequency of the signal. …”
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Ferroportin 1 depletion in neural stem cells promotes hippocampal neurogenesis and cognitive function in mice by Yiqian Ding, Shanshan Yao, Shuxin Guo, Wei Meng, Jie Li, Fudi Wang, Jianhua Zhang, Yan-Zhong Chang, Guofen Gao

“…This study reveals that Fpn1 of NSCs and its regulated iron levels are key modulators of hippocampal neurogenesis through promoting the proliferation of NSCs and ultimately controlling hippocampal function. …”
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Single-cell transcriptomics reveals metabolic remodeling and functional specialization in the immune microenvironment of bone tumors by Jun Chen, Na Cui, Shao-Hui He, Chun-Yan Xia, Wei-Qing Li

“…Our findings highlight potential therapeutic targets for modulating immune cell function and offering new avenues to improve treatment outcomes for patients with bone tumors.…”
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Expansins in Salt and Drought Stress Adaptation: From Genome-Wide Identification to Functional Characterisation in Crops by Siarhei A. Dabravolski, Stanislav V. Isayenkov

“…This manuscript explores the functions of expansins in salt and drought stress responses across multiple plant species, highlighting their involvement in cell wall loosening, transcriptional regulation, ion and osmotic homeostasis, and phytohormone signalling. …”
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Impact of Biochar on Nitrogen-Cycling Functional Genes: A Comparative Study in Mollisol and Alkaline Soils by Junnan Ding, Shaopeng Yu

“…The results demonstrated that biochar significantly altered the microbial community structure by modulating the abundance of these functional genes. …”
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The RhoGEF trio functions in sculpting class specific dendrite morphogenesis in Drosophila sensory neurons. by Srividya Chandramouli Iyer, Dennis Wang, Dennis Wang, Eswar Prasad R Iyer, Sarah A Trunnell, Ramakrishna Meduri, Riaz Shinwari, Mikolaj J Sulkowski, Daniel N Cox

“…Moreover, the specification of class specific dendrite arborization is critically important in establishing neural connectivity and the formation of functional networks. Cytoskeletal modulation provides a key mechanism for establishing, as well as reorganizing, dendritic morphology among distinct neuronal subtypes. …”
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Is Autonomic Function Associated with (Central) Pain Processing in Individuals with Chronic Pain? A Systematic Review by Iris Meuwissen, Catharina Quaadvliet, Mira Meeus, Timo Meus, Michel GCAM Mertens

“…Weak evidence was found for the association between autonomic function (heart rate and blood pressure) and pain sensitivity to rectal distension in patients with IBS (P < 0.05); an inverse relation between plasma catecholamines and pressure pain thresholds (P = 0.042) in chronic pancreatitis; and lower heart rate variability in patients with chronic musculoskeletal pain and impaired conditioned pain modulation (P < 0.01). …”
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Understanding the impact of moxifloxacin on immune function: Findings from cytokine analyses and immunological assays in mice. by Mehmood Ahmad, Naeem Rasool, Rana Muhammad Zahid Mushtaq, Sammina Mahmood, Abdur Rauf Khalid, Waqas Ahmad, Bilal Mahmood Beg, Mostafa A Abdel Maksoud, Abdul Aziz Alamri, Adeel Sattar

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Genome-wide identification and functional characterization of NOD-like receptors (NLRs) in snakehead (Channa argus) by Xiaochen Zhu, Beibei Wang, Lu Zhang, Xiaoyan Zhang, Chao Li

“…This study offers robust evidence that enhances our understanding of the immune regulatory mechanisms and functional roles of NLR genes in snakehead.…”
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Plastic Responses of <i>Iris pumila</i> Functional and Mechanistic Leaf Traits to Experimental Warming by Katarina Hočevar, Ana Vuleta, Sanja Manitašević Jovanović

“…In particular, we investigated important functional and mechanistic leaf traits: specific leaf area (SLA), leaf dry matter content (LDMC), specific leaf water content (SLWC), stomatal density (SD), leaf thickness (LT), and chlorophyll content. …”
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Pharmacological Blocking of Adiponectin Receptors Induces Alzheimer’s Disease-like Neuropathology and Impairs Hippocampal Function by Hui-Hui Guo, Hai-Ning Ou, Jia-Sui Yu, Suk-Yu Yau, Hector Wing-Hong Tsang

“…<b>Conclusions</b>: These findings highlight the critical role of peripheral manipulation of adiponectin receptors in modulating cognitive function and adult neurogenesis, offering insights into potential therapeutic strategies for AD and related cognitive disorders.…”
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From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

“…Key health benefits include immune modulation, antioxidative effects, mental health support, ocular health preservation, and metabolic and cardiovascular regulation. …”
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Cannabidiol as a multifaceted therapeutic agent: mitigating Alzheimer's disease pathology and enhancing cognitive function by Iu Raïch, Jaume Lillo, Joan Biel Rebassa, Christian Griñán-Ferré, Aina Bellver-Sanchis, Irene Reyes-Resina, Rafael Franco, Mercè Pallàs, Gemma Navarro

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Functional diversification of the MADS-box gene family in fine-tuning the dimorphic transition of Talaromyces marneffei by Xueyan Hu, Yun Zhang, Juan Wang, Minghao Du, Yang Yang, James J. Cai, Ence Yang

“…In the current study, we elucidated the roles of the MADS-box family in fine-tuning the dimorphic transition in T. marneffei through functional diversification of members. Utilizing adaptive laboratory evolution, we identified an enrichment of MADS-box genes in mutants deficient in yeast-to-mycelium transition. …”
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