Effectiveness of dietary interventions in managing pediatric gastroesophageal reflux disease: a comprehensive systematic review by Abdulrahman A. Alnaim

“…Probiotics emerged as a promising intervention, reducing GERD symptoms by enhancing gut barrier function and modulating inflammation. However, the studies varied in design, and adherence to dietary interventions was identified as a key challenge, particularly in pediatric populations. …”
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Influence of Interleukin-8 and Neutrophil Extracellular Trap (NET) Formation in the Tumor Microenvironment: Is There a Pathogenic Role? by Manuela Gonzalez-Aparicio, Carlos Alfaro

“…However, the extent to which NETs affect the function of other cells of the immune system in the tumor context has not been directly demonstrated. …”
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Cloning and expression analysis of maize fucosyltransferase gene SPINDLY by LI Bowen, WANG Zhiqin, ZHU Xiaona, ZHU Zhenyu, GAO Xiaoxiao*

“…In order to explore the function of maize fucosyltransferase gene(ZmSPY), this study first analyzed the conserved domain, amino acid sequence and physicochemical properties of ZmSPY protein by bioinformatics means, and cloned the gene from maize root tissue to construct the GFP fusion protein expression vector. …”
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Methods of Extracorporeal Hemocorrection in Sepsis (Review) by V. A. Kovzel, L. A. Davydova, A. V. Karzin, S. V. Tsarenko, V. Yu. Baturova, A. A. Polupan, A. I. Gutnikov

“…Currently, EHC methods are increasingly used not only to support renal function, but also as pathogenetic therapy option for multiple organ support and immunomodulation by reducing the level of cir-culating inflammatory mediators. …”
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Exploring the Mechanism of Luteolin in Protecting Chickens from Ammonia Poisoning Based on Proteomic Technology by Yu Jin, Azi Shama, Haojinming Tang, Ting Zhao, Xinyu Zhang, Falong Yang, Dechun Chen

“…Results: Gene Ontology (GO) analysis showed DEPs enriched in molecular responses to interferons and the negative regulation of immune responses, mainly located extracellularly. Molecular function analysis revealed DEPs in antigen binding and synthase activity. …”
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Phosphodiesterase inhibition and Gucy2C activation enhance tyrosine hydroxylase Ser40 phosphorylation and improve 6-hydroxydopamine-induced motor deficits by Erik H. Douma, Jesse Stoop, Matthijs V. R. Lingl, Marten P. Smidt, Lars P. van der Heide

“…Conclusions This study underscores the therapeutic potential of enhancing tyrosine hydroxylase Ser40 phosphorylation to improve motor function in Parkinson’s disease. Both PDE inhibition and GUCY2C activation represent promising non-invasive strategies to modulate endogenous dopamine biosynthesis and address motor deficits. …”
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Sending the Signal to Bone: How Tumor-Derived EVs Orchestrate Pre-Metastatic Niche Formation and Skeletal Colonization by Alhomam Dabaliz, Hagar Mahmoud, Raffi AlMutawa, Khalid S. Mohammad

“…We then outline the sequential establishment of the pre-metastatic niche, driven by EV-mediated processes including fibronectin deposition, stromal cell reprogramming, angiogenesis, neurogenesis, metabolic reconfiguration, and immune modulation, specifically, the expansion of myeloid-derived suppressor cells and impaired lymphocyte function. …”
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Stem cell and CRISPR/Cas9 gene editing technology in Alzheimer’s disease therapy: from basic research to clinical innovation by Cong He, Baojiang Chen, Ciai Yan, Xiaoqing Zhou

“…The key findings suggest that gene-edited iPSCs can reduce abnormal Aβ and tau protein accumulation in AD models, improve cognitive function, and provide a platform for disease modeling and drug screening. …”
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A Lactobacillus consortium provides insights into the sleep-exercise-microbiome nexus in proof of concept studies of elite athletes and in the general population by Tindaro Bongiovanni, Marina Santiago, Kinga Zielinska, Jonathan Scheiman, Carolina Barsa, Ralf Jäger, Daniela Pinto, Fabio Rinaldi, Giammaria Giuliani, Tullio Senatore, Aleksandar D. Kostic

“…Multi-omics analyses revealed specific changes in microbiome composition and function, potentially providing mechanistic insights into these observed effects. …”
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Genetic Basis and Simulated Breeding Strategies for Enhancing Soybean Seed Protein Content Across Multiple Environments by Xu Sun, Bo Hu, Wen-Xia Li, Hai-Long Ning

“…Finally, simulated breeding was conducted using the B4L function in the In Silico Breeding (ISB) module of the Blib platform to determine optimal breeding strategies across diverse environments. …”
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Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. by Rahul C Deo, David Reich, Arti Tandon, Ermeg Akylbekova, Nick Patterson, Alicja Waliszewska, Sekar Kathiresan, Daniel Sarpong, Herman A Taylor, James G Wilson

“…Strikingly, the extensively studied "gain-of-function" S447X mutation at LPL, which has been hypothesized to be the major determinant of the LPL-TG genetic association and is in trials for human gene therapy, has a significantly diminished strength of biological effect when it is found on a background of African rather than European ancestry. …”
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Uteroplacental Insufficiency Alters the Retinoid Pathway and Lung Development in Newborn Rats by Liang-Ti Huang, Hsiu-Chu Chou, Chun-Mao Lin, Chung-Ming Chen

“…Intrauterine growth retardation (IUGR) is associated with reduced lung function during infancy and perhaps throughout adulthood. …”
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Divergent Molecular Responses to Heavy Water in <i>Arabidopsis thaliana</i> Compared to Bacteria and Yeast by Pengxi Wang, Jan Novák, Romana Kopecká, Petr Čičmanec, Martin Černý

“…Heavy water (D₂O) is scarce in nature, and despite its physical similarity to water, D₂O disrupts cellular function due to the isotope effect. While microbes can survive in nearly pure D₂O, eukaryotes such as <i>Arabidopsis thaliana</i> are more sensitive and are unable to survive higher concentrations of D₂O. …”
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YOLO-SAG: An improved wildlife object detection algorithm based on YOLOv8n by Lingli Chen, Gang Li, Shunkai Zhang, Wenjie Mao, Mei Zhang

“…Training stability is enhanced by introducing the Softplus activation function, which increases detection accuracy; incorporating the AIFI enhances intra-scale feature interaction, reducing missed and false detections. …”
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LePB-SA4RE: A Lexicon-Enhanced and Prompt-Tuning BERT Model for Evolving Requirements Elicitation from App Reviews by Zhiquan An, Hongyan Wan, Teng Xiong, Bangchao Wang

“…To mitigate these issues, this study introduces LePB-SA4RE, a novel ABSA model that integrates the Bidirectional Encoder Representations from Transformers (BERT) architecture with a hard template-based PT method and embeds a lexicon-enhanced dynamic modulation layer. Specifically, the activation function of this layer incorporates weights designed with sentiment-oriented dynamic parameters to enhance the sensitivity of the model to diverse sentiment inputs, and a sentiment lexicon containing three hundred thousand word–sentiment polarity pairs is embedded into the model as additional semantic cues to increase prediction accuracy. …”
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Critical Component Overheating Monitoring Algorithm Integrating Temperature-sensing Patches and Computer Vision Trains by SHU Dong, ZHANG Beijia, YANG Hongtai

“…A main-boundary separation module is embedded in the U-Net++ network architecture, and corresponding boundary supervision terms are added to the loss function, so that boundary segmentation performance could be enhanced and segmentation precision of temperature-sensing patches in the image be improved. …”
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BCSM-YOLO: An Improved Product Package Recognition Algorithm for Automated Retail Stores Based on YOLOv11 by Pingqing Hou, Shaoze Huang

“…Then, the Convolutional Block Attention Module (CBAM) screens the processed data, adaptively focuses on the key regions, and suppresses the background interference. …”
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Potassium Clearance in Optic Nerve: A Multidomain Model by Shanfeng Xiao, Huaxiong Huang, Robert Eisenberg, Zilong Song, Shixin Xu

“…Understanding the coordinated roles of glial cells and perivascular spaces in regulating ionic and fluid homeostasis is essential for interpreting neural function and dysfunction. …”
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Molecular Dynamics of Apolipoprotein Genotypes APOE4 and SNARE Family Proteins and Their Impact on Alzheimer’s Disease by Yuqing Wang, Xuefeng Liu, Pengtao Zheng, Qing Xie, Chenxiang Wang, Chaoyang Pang

“…This work highlights the perturbations in synaptic function mediated by APOE4, which may offer novel insights into the molecular underpinnings of AD. …”
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Seasonal Temperature Distributions and Variations in Salt Marshes: Field Investigation and Numerical Simulation by Xiayang Yu, Xinghua Xu, Lucheng Zhan, Haifeng Cheng, Pei Xin

“…A regression model incorporating a Gamma distribution function was developed to quantify the delayed and cumulative thermal effects of tidal water and air on shallow soil temperatures. …”
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