Emerging regenerative strategies for spinal cord injury: exosome-derived mechanisms and therapeutic insights by Haixia Fan, Jie Gao, Qian Chen, Shuangshuang Sun, Jinshen Guo, Xiaodong Liu, Jinhu Li

“…Keyword analysis focuses on “mesenchymal stem cells,” “inflammation,” “cell therapy,” “axonal regeneration,” “functional recovery,” “neuroinflammation,” “neurodegeneration,” “ferroptosis,” “pyroptosis,” and “precision medicine” emphasizing cellular therapies for tissue repair. …”
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Correlation Between miR-27a-3p Polymorphisms and Peri-Implantitis Susceptibility: A Case-Control Study by Xiaojie Gao, Yanan Ha

“…Overlap genes were compiled by the Venn diagram. Functional enrichment analysis for target genes was performed via Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Protein-Protein Interaction (PPI) networks. …”
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ResGRU: A Novel Hybrid Deep Learning Model for Compound Fault Diagnosis in Photovoltaic Arrays Considering Dust Impact by Xi Liu, Hui Hwang Goh, Haonan Xie, Tingting He, Weng Kean Yew, Dongdong Zhang, Wei Dai, Tonni Agustiono Kurniawan

“…To further optimize inter-class separability and intra-class compactness, a center loss function is employed as an auxiliary loss to enhance the model’s discriminative capacity. …”
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MS-YOLOv8: multi-scale adaptive recognition and counting model for peanut seedlings under salt-alkali stress from remote sensing by Fan Zhang, Longgang Zhao, Longgang Zhao, Dongwei Wang, Jiasheng Wang, Igor Smirnov, Juan Li

“…Additionally, the module automatically adjusts the channel weights of each group based on their contribution, improving the feature fusion effect. …”
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Pavement Disease Visual Detection by Structure Perception and Feature Attention Network by Bin Lv, Shuo Zhang, Haixia Gong, Hongbo Zhang, Bin Dong, Jianzhu Wang, Cong Du, Jianqing Wu

“…To further improve robustness, the generalized intersection over union (GIoU) loss function is adopted, ensuring better stability across targets of varying shapes and sizes. …”
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Association of Platelet Binding to Lymphocytes with B Cell Abnormalities and Clinical Manifestations in Systemic Lupus Erythematosus by Carlos Zamora, Elide Toniolo, Cesar Diaz-Torné, Elisabet Cantó, Berta Magallares, Ma Angels Ortiz, Lidia Perea, Hector Corominas, Silvia Vidal

“…Immunological factors derived from platelets modulate B cell function in SLE disease. However, platelets do not only modify the immune system by soluble factors. …”
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Postoperative symptom network analysis in non-small cell lung cancer patients: a cross-sectional study by Sha Zhang, Yao Deng, Xiaorun Xiang, Qianfeng Xu, Lixin Hu, Mei Xia, Lei Liu

“…A symptom network was constructed with R software with the EBICgloss function and Spearman correlation analysis, and the centrality indicators were then calculated. …”
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Targeting the mTOR-Autophagy Axis: Unveiling Therapeutic Potentials in Osteoporosis by Rongjin Chen, Chenhui Yang, Fei Yang, Ao Yang, Hefang Xiao, Bo Peng, Changshun Chen, Bin Geng, Yayi Xia

“…Despite advances, significant gaps remain in understanding the detailed mechanisms of mTOR’s effects on autophagy and bone cell function, highlighting the need for comprehensive clinical trials to establish the efficacy and safety of mTOR inhibitors in OP management. …”
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The effects of candidate probiotic strains on the gut environment in dextran sulfate sodium-induced colitis mouse by Kung Ahn, Kyung-Wan Baek, Kyeongeui Yun, Yunseok Oh, Yong Sung Kim, Eunok Im, Yunna Lee, Jieun Choi, Eun-Ji Song, Yong-Soo Park, Dong Ho Lee, Wonsuk Lee, Do Yup Lee, Kyudong Han, Yong Ju Ahn

“…In this study, our primary objective was to determine whether ingestion of these strains alleviates colitis symptoms and, if so, to elucidate how they restored gut microbial balance and modulated microbial metabolic functions. In most probiotic-treated groups, colitis disease activity index scores were significantly improved and colon length was preserved, with strains CBA7106 and BBH exhibiting efficacy comparable to that of the Lactobacillus rhamnosus GG (used as a positive control). …”
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Identification of long noncoding RNAs (lncRNAs) and co-transcriptional analysis of mRNAs and lncRNAs in transcriptomes of Anopheles gambiae by Jiannong Xu, Kai Hu, Michelle M. Riehle, Vedbar S. Khadka

“…Co-expression networks constructed using weighted gene co-expression network analysis (WGCNA) highlighted the interconnections among lncRNAs and mRNAs, which provide potential functional networks in which these lncRNAs are involved. …”
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Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation by Jie Chen, Yiwei Zhao, Chongmai Zeng, Guoli Tian, Zhicai Feng, Yang Cao

“…Abstract Background Craniomaxillofacial sutures play a critical role in craniomaxillofacial development through continuous bone reconstruction and regeneration, processes modulated by mechanical tension. Bone suture stem cells (SuSCs) are central to these functions. …”
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A novel Fe/S catalyst approach used to successfully synthesize 2D hexagonal boron-nitride structures by Rodrigo Nunes de Souza, Mauro Francisco Pinheiro da Silva, Alysson Martins Almeida Silva, Alisson Mendes Rodrigues, Alexandre Silva Santos, Sebastião William da Silva, José Antonio Huamaní Coaquira, Wellington Marcos da Silva

“…Iron serves as the primary catalyst, whereas sulfur acts as a promoter, modulating the catalytic activity and selectivity of the process. …”
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The invasion phenotypes of glioblastoma depend on plastic and reprogrammable cell states by Milena Doroszko, Rebecka Stockgard, Irem Uppman, Josephine Heinold, Faidra Voukelatou, Hitesh Bhagavanbhai Mangukiya, Thomas O. Millner, Madeleine Skeppås, Mar Ballester Bravo, Ramy Elgendy, Maria Berglund, Ludmila Elfineh, Cecilia Krona, Soumi Kundu, Katarzyna Koltowska, Silvia Marino, Ida Larsson, Sven Nelander

“…Our results define a close association between GBM cell differentiation states and invasion routes, identify functional biomarkers of route-specific invasion, and point toward targeted modulation of specific invasive cell states as a therapeutic strategy in GBM.…”
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Evaluation of the Effect of Light Color on Albumins and Globulins Content During Bean Germination by Victor Manuel Rivera Aguilar, José Pedraza-Chaverri, David Julian Arias-Chávez, Ruth Jaimez, Edgar Flores-Soto, Isaías E. Garduño, Fernando S. Chiwo, Celia Sánchez Pérez, Ana del Carmen Susunaga Notario

“…These findings highlight the potential of controlled lighting conditions to enhance the nutritional quality of germinated beans, supporting their application as functional food ingredients. Additionally, this study underscores the importance of photobiological modulation in seed germination, opening new possibilities for optimizing plant-based protein sources. …”
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FECAL MICROBIOTA TRANSPLANTATION IN CRITICAL CONDITION PATIENTS IN HEMATOLOGICAL PRACTICE by O. V. GOLOSHCHAPOV, D. V. CHURAKINA, M. А. KUCHER, R. V. KLEMENTEVA, S. V. SIDORENKO, V. V. GOSTEV, V. Е. KAREV, М. А. SUVOROVA, I. V. SHLYK, А. B. CHUKHLOVIN, L. S. ZUBAROVSKAYA, B. V. AFANASYEV

“…According to literature data, fecal microbiota transplantation (FMT) may be applied to restore functional activity of microbiota and to overcome antibiotic resistance. …”
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Ion-Channel-Targeting Scorpion Recombinant Toxin as Novel Therapeutic Agent for Breast Cancer by Natalia Mata de los Rios, Argel Gastelum-Arellanez, Herlinda Clement, Karely Álvarez-Cruz, Diana Romero-Terrazas, Carolina Alvarado-González, Luis Carlos Hinojos-Gallardo, Gerardo Corzo, Gerardo Pável Espino-Solis

“…Through chromatographic separation, mass spectrometry, and functional assays, we assess their effects on cell viability, proliferation, and ion channel modulation. …”
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Preliminary findings from a retrospective comparative study on a novel hydrophobic C-loop monofocal intraocular lens by Youngsub Eom, Jeongmin Kim, Hungwon Tchah, Kyungmin Koh

“…The optical bench test measured the root mean square of the modulation transfer function (MTTRMS) of each IOL at defocus levels between +1.00 D and −2.50 D at intervals of 0.25 D at varying pupil sizes (2.0–5.0 mm) in 1.0 mm steps. …”
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Precision Weed Management for Straw-Mulched Maize Field: Advanced Weed Detection and Targeted Spraying Based on Enhanced YOLO v5s by Xiuhong Wang, Qingjie Wang, Yichen Qiao, Xinyue Zhang, Caiyun Lu, Chao Wang

“…Secondly, we proposed an improved YOLO v5s network, incorporating a Convolutional Block Attention Module (CBAM), FasterNet feature extraction network, and a loss function to optimize the network structure and training strategy. …”
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RMVAD-YOLO: A Robust Multi-View Aircraft Detection Model for Imbalanced and Similar Classes by Keda Li, Xiangyue Zheng, Jingxin Bi, Gang Zhang, Yi Cui, Tao Lei

“…Additionally, to further leverage background information and enhance the model’s adaptability to multi-scale target variations, we incorporate the LSK Module into the backbone network. Finally, we propose the WFMIoUv3 loss function, which strengthens the model’s focus on challenging samples and improves detection robustness. …”
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Transposon insertion in pmel17 rewired skin and muscle transcriptomes in Mozambique tilapia by Fei Sun, Le Wang, Gen Hua Yue

“…Furthermore, several DEGs associated with muscle function and mobility were up-regulated. Our study sheds light on how a single mutation in a gene can modulate multiple phenotypes by rewiring gene regulation networks. …”
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