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10501
Strategic Doping for Precise Structural Control and Intense Photocurrents Under Visible Light in Ba<sub>2</sub>M<sub>0.4</sub>Bi<sub>1.6</sub>O<sub>6</sub> (M = La, Ce, Pr, Pb, Y)...
Published 2025-07-01“…Developing functional perovskites is important for advancing solar energy conversion technologies. …”
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10502
Modulatory Role of Hesperetin–Copper(II) on Gut Microbiota in Type 2 Diabetes Mellitus Mice
Published 2025-07-01“…Flavonoid–metal complexes have become one of the research hotspots in the field of health foods due to their unique structural and functional properties. Methods: In this study, the effect of hesperetin–copper(II) complex [Hsp–Cu(II)] on the gut microbiota of mice with T2DM was investigated by the 16S rRNA high-throughput sequencing. …”
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10503
In Vitro Neuroprotective Effects of a Mixed Extract of Bilberry, <i>Centella asiatica</i>, <i>Hericium erinaceus</i>, and Palmitoylethanolamide
Published 2025-07-01“…These findings suggest that this nutraceutical combination may support the cellular pathways involved in neuronal resilience and healthy brain ageing, offering potential as a functional food ingredient or dietary supplement.…”
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10504
Features of quantitative EEG in children with hyperkinetic disorder
Published 2022-04-01“…In the selected groups, the serotonin system plays an inhibitory and modulating role in relation to the catecholamine metabolism systems. …”
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10505
Green solvents assisted de-novo synthesis and defect-engineered UiO-66 for improved CO2 adsorption and kinetics- experimental and DFT approach
Published 2024-12-01“…Furthermore, through periodic Density Functional Theory (DFT) calculations, a variety of linker defects are engineered onto the UiO-66 structure to preserve more open metal sites. …”
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10506
The effect of protein intake levels on early postoperative outcomes following impacted mandibular third molar removal: a pilot study
Published 2025-06-01“…Conclusions Higher protein intake was associated with improved early wound healing and modulation of postoperative outcomes, including reduced pain severity and enhanced functional recovery following third molar surgery. …”
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10507
Genome-wide identification and classification of MYB superfamily genes in peach.
Published 2018-01-01“…This study laid the foundation for further functional analysis of MYB superfamily genes in peach and enriched the knowledge of MYB superfamily genes in plant species.…”
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10508
SAMHD1 enhances HIV-1-induced apoptosis in monocytic cells via the mitochondrial pathway
Published 2025-07-01“…In this study, we aim to bridge this knowledge gap by investigating the functional significance of SAMHD1 in regulating apoptosis during HIV-1 infection of immune cells. …”
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10509
Genome-Wide Identification of the <i>Eceriferum</i> Gene Family and Analysis of Gene Expression Patterns Under Different Treatments in Pepper (<i>Capsicum annuum</i> L.)
Published 2025-05-01“…Future work should employ gene editing and metabolomics to validate functional mechanisms and optimize breeding strategies.…”
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10510
β-cyclodextrin-based multifunctional carriers for colon-targeted drug delivery: advances in hydrogel systems and mucoadhesive strategies
Published 2025-08-01“…Abstract Oral drug delivery to the colon remains a formidable challenge due to the harsh conditions of the upper gastrointestinal tract, including variable pH, enzymatic degradation, and limited mucosal permeability. β-Cyclodextrin (β-CD), a cyclic oligosaccharide with a hydrophobic cavity and hydrophilic exterior, offers a promising approach to overcome these barriers by forming stable inclusion complexes that protect sensitive drugs and modulate their release profile. This review explores the use of native and chemically modified β-CDs as functional carriers for colonic drug delivery, with a focus on hydrogel-based systems, mucoadhesive derivatives, and microbiota-responsive formulations. …”
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10511
Quantitative proteomic analysis deciphers mechanisms of sheath blight resistance in novel rice landrace against Rhizoctonia solani
Published 2025-08-01“…The analysis unveiled 5133 differentially expressed proteins, with 118 significantly upregulated and 172 significantly downregulated at 0.05 p-value. Functional annotation revealed that the proteins associated with jasmonic acid-induced systemic resistance (JA-ISR), brassinosteroid (BR) signaling pathway, terpenoid biosynthesis, cell wall remodeling and carbohydrate metabolism showed significant upregulation in Nizam Shait upon ShB infection. …”
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10512
Identifying and Diagnosing Lytic Cell Death Genes in Atherosclerosis Using Machine Learning and Bioinformatics
Published 2025-07-01“…Two subtypes, C1 (non-immune subtype) and C2 (immune subtype), were delineated based on immune landscape analysis and gene set variation analysis functional enrichment. The chi-square test revealed that C1 was linked to early-stage (low-risk) atherosclerotic plaques, whereas C2 was associated with advanced-stage (high-risk) atherosclerotic plaques. …”
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10513
Predictive prioritization of genes significantly associated with biotic and abiotic stresses in maize using machine learning algorithms
Published 2025-06-01“…The top-ranked genes predicted to be key players in multiple stress resistance in maize need to be functional validated to ascertain their roles and further utilization in developing stress-resistant maize varieties.…”
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10514
Genome-Wide Identification and Cold Stress Response Mechanism of Barley Di19 Gene Family
Published 2025-05-01“…Under cold stress, different barley varieties exhibited distinct <i>HvDi19</i> gene expression profiles: for instance, <i>HvDi19-1</i> was downregulated in cold-tolerant varieties, whereas <i>HvDi19-7</i> showed increased expression in a cold-tolerant mutant, suggesting their potential roles in modulating cold response. These findings reveal the evolutionary conservation and cold-responsive expression characteristics of the <i>HvDi19</i> gene family, laying a foundation for future functional studies. …”
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10515
Elucidating the role of KCTD10 in coronary atherosclerosis: Harnessing bioinformatics and machine learning to advance understanding
Published 2025-03-01“…Among 10 DEGs linked with KCTD10, 13 were identified as hub genes through LASSO and SVM-RFE analyses. Functional assays highlighted KCTD10’s role in enhancing viral defense mechanisms, cytokine production, and immune cascades. …”
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10516
Identification and analysis of the endoplasmic reticulum stress hub genes in sepsis-associated ARDS
Published 2025-08-01“…A comprehensive evaluation was performed by integrating functional enrichment analysis, immune cell infiltration analysis, and weighted gene co-expression network analysis (WGCNA). …”
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10517
Efficacy and safety of the early implementation of a multimodal rehabilitation program in mechanically ventilated patients: A randomized clinical trial protocol.
Published 2025-01-01“…., active-assisted exercises and functional mobility activities). For patients with RASS ≥2, occupational therapy will focus on behavioral and environmental modulation, employing calming techniques, sensory stimuli, and cognitive tasks, with family education to support spatiotemporal orientation. …”
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10518
Macrophage polarization in sarcoidosis
Published 2021-03-01“…The macrophage population is characterized by plasticity and functional heterogeneity. In response to various signals from the microenvironment, macrophages are able to acquire certain phenotypes. …”
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10519
Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life.
Published 2014-01-01“…The expression levels of miR-15/16, miR-29 and miR-196 were positively correlated with the copy numbers of 16S rRNA gene of Bifidobacterium or Lactobacillus species or both (P<0.05). Functional analysis using Ingenuity Pathway Analysis identified the above mentioned differentially expressed miRNAs as potential regulators of gut tissue cell proliferation and differentiation. …”
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10520
Biofortified Calcium Phosphate Nanoparticles Elicit Secondary Metabolite Production in Carob Callus via Biosynthetic Pathway Activation
Published 2025-07-01“…To address this, we use biofortified calcium phosphate nanoparticles, which refer to CaP-NPs that have been enriched with bioactive compounds via green synthesis using Jania rubens extract, thereby enhancing their functional properties as elicitors in carob callus. …”
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